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Journal Articles

Targeting CD161 in B-cell malignancies

Matthew D. Blunt

Blood (2024) 143 (12): 1061–1062.

https://doi.org/10.1182/blood.2023023785

Published: 2024

Journal Articles

Selinexor Enhances Natural Killer Cell Function Against Multiple Myeloma Cells

Jack G Fisher, Amber DP Doyle, Lara V Graham, Francesco Forconi, Mark S Cragg, Christopher J Walker, Salim I Khakoo, Matthew D Blunt

Blood (2023) 142 (Supplement 1): 6599.

https://doi.org/10.1182/blood-2023-179744

Published: 2023

Journal Articles

Selinexor Enhances NK Cell Activation Against Lymphoma Cells Via Downregulation of HLA-E

Jack Fisher, Christopher J. Walker, Peter Johnson, Mark S Cragg, Francesco Forconi, Yosef Landesman, Salim I Khakoo, Matthew D Blunt

Blood (2021) 138 (Supplement 1): 2411.

https://doi.org/10.1182/blood-2021-144836

Published: 2021

Journal Articles

PI3Kδ/AKT Inhibition Augments 2-Phenylethynesulfonamide Induced Apoptosis Via the Unfolded Protein Response in Chronic Lymphocytic Leukemia

Matthew D Blunt, PhD, Lindsay D Smith, PhD, Adam Linley, PhD BSc, Jonathan C Strefford, PhD, Peter Johnson, Francesco Forconi, MD DM, PhD FRCPath, Freda K. Stevenson, DPhil, Graham Packham, PhD, Andrew J Steele, PhD

Blood (2017) 130 (Supplement 1): 4290.

https://doi.org/10.1182/blood.V130.Suppl_1.4290.4290

Published: 2017

Journal Articles

Regulation and Impact of BCR Induced Autophagy in Chronic Lymphocytic Leukemia

Lindsay D Smith, PhD, Laura I Karydis, PhD, Margaret Ashton-Key, MD, Jonathan C Strefford, PhD, Freda K. Stevenson, DPhil, Graham Packham, PhD, Mark Cragg, PhD, David A Tumbarello, PhD, Matthew D Blunt, PhD, Francesco Forconi, MD DM, PhD FRCPath, Andrew J Steele, PhD

Blood (2017) 130 (Supplement 1): 1717.

https://doi.org/10.1182/blood.V130.Suppl_1.1717.1717

Published: 2017

Journal Articles

Releasing the brakes on BTK-targeting miRNA

Matthew D. Blunt, Andrew J. Steele

Blood (2016) 128 (26): 3023–3024.

https://doi.org/10.1182/blood-2016-11-748145

Published: 2016

Journal Articles

Regulation of B-Cell Receptor Signalling By the Tumour Microenvironment in Chronic Lymphocytic Leukemia (CLL) and Its Impact on Adhesion and miRNA Expression

Matthew D Blunt, PhD, Rachel Dobson, BSc(Hons), Lindsay D Smith, PhD, Jonathan C. Strefford, Pamela B. Conley, PhD, Anjali Pandey, PhD, Andrew J Davies, FRCP PhD, Peter M Johnson, MA, MD, Graham Packham, PhD, Freda K Stevenson, DPhil, Francesco Forconi, MD DM, PhD FRCPath, Greg P Coffey, PhD, Andrew J Steele, PhD

Blood (2016) 128 (22): 351.

https://doi.org/10.1182/blood.V128.22.351.351

Published: 2016

Journal Articles

To BH3 profile or not to BH3 profile

Matthew D. Blunt, Andrew J. Steele

Blood (2016) 127 (25): 3111–3112.

https://doi.org/10.1182/blood-2016-04-711762

Published: 2016

Journal Articles

IL-4 enhances expression and function of surface IgM in CLL cells

Maria M. Aguilar-Hernandez, Matthew D. Blunt, Rachel Dobson, Alison Yeomans, Stephen Thirdborough, Marta Larrayoz, Lindsay D. Smith, Adam Linley, Jonathan C. Strefford, Andrew Davies, Peter M. W. Johnson, Natalia Savelyeva, Mark S. Cragg, Francesco Forconi, Graham Packham, Freda K. Stevenson, Andrew J. Steele

Blood (2016) 127 (24): 3015–3025.

https://doi.org/10.1182/blood-2015-11-682906

Published: 2016

Includes: Supplemental data

Journal Articles

Biological Significance of B Cell Receptor Mediated Regulation of Autophagy in Chronic Lymphocytic Leukemia

Lindsay Smith, PhD, Elizabeth Hogg, BSc(Hons), Angus Haynes, Jonathan C Strefford, PhD, Francesco Forconi, MD DM, PhD FRCPath, Freda K Stevenson, DPhil, Graham Packham, PhD, Mark S Cragg, PhD, David Tumbarello, Matthew D Blunt, PhD, Andrew J Steele, PhD

Blood (2015) 126 (23): 4130.

https://doi.org/10.1182/blood.V126.23.4130.4130

Published: 2015

Journal Articles

The Syk\Jak Inhibitor Cerdulatinib (PRT062070) Shows Promising Preclinical Activity in Chronic Lymphocytic Leukemia By Antagonising B Cell Receptor and Microenvironmental Signalling

Matthew D Blunt, PhD, Jack Parnell, BSc(hons), Marta Larrayoz, PhD, Lindsay Smith, PhD, Rachel Dobson, BSc(Hons), Jonathan C Strefford, PhD, Freda K Stevenson, DPhil, Francesco Forconi, MD DM, PhD FRCPath, Andrew J Davies, MRCP, Peter W Johnson, MD, Graham Packham, PhD, Greg P. Coffey, PhD, Mark S Cragg, PhD, Andrew J Steele, PhD

Blood (2015) 126 (23): 1716.

https://doi.org/10.1182/blood.V126.23.1716.1716

Published: 2015

Journal Articles

The PI3K/mTOR inhibitor PF-04691502 induces apoptosis and inhibits microenvironmental signaling in CLL and the Eµ-TCL1 mouse model

Matthew D. Blunt, Matthew J. Carter, Marta Larrayoz, Lindsay D. Smith, Maria Aguilar-Hernandez, Kerry L. Cox, Thomas Tipton, Mark Reynolds, Sarah Murphy, Elizabeth Lemm, Samantha Dias, Andrew Duncombe, Jonathan C. Strefford, Peter W. M. Johnson, Francesco Forconi, Freda K. Stevenson, Graham Packham, Mark S. Cragg, Andrew J. Steele

Blood (2015) 125 (26): 4032–4041.

https://doi.org/10.1182/blood-2014-11-610329

Published: 2015

Includes: Supplemental data

Journal Articles

The Dual PI3K/mTOR Inhibitor PF-04691502 Induces Substantial Apoptosis in Chronic Lymphocytic Leukemia Cells in Vitro and Prolongs Survival in the Eµ-TCL1 Mouse Model

Matthew D Blunt, PhD, Matthew J Carter, PhD, Marta Larrayoz, PhD, Maria Montserrat Aguilar, PhD, Sarah Murphy, Mark Reynolds, Thomas Tipton, Kerry Cox, Jonathan C Strefford, PhD, Freda K Stevenson, DPhil, Francesco Forconi, Graham Packham, PhD, Mark Cragg, PhD, Andrew J Steele, PhD

Blood (2014) 124 (21): 832.

https://doi.org/10.1182/blood.V124.21.832.832

Published: 2014

Journal Articles

IL-4 Exerts Opposing Effects on Surface-IgM and CXCR4 Mediated Signalling in Chronic Lymphocytic Leukaemia

Maria Montserrat Aguilar, PhD, Matthew D Blunt, PhD, Jonathan C Strefford, PhD, Francesco Forconi, MD DM, PhD FRCPath, Mark Cragg, PhD, Freda K Stevenson, DPhil, Graham Packham, PhD, Andrew J Steele, PhD

Blood (2014) 124 (21): 3299.

https://doi.org/10.1182/blood.V124.21.3299.3299

Published: 2014

Journal Articles

Modulation of B Cell Receptor Signalling By IL-4 In Chronic Lymphocytic Leukaemia

Maria Aguilar-Hernandez, PhD, Matthew D Blunt, PhD, Jonathan C Strefford, Andrew Duncombe, MD, Francesco Forconi, MD, PhD, Freda K. Stevenson, DPhil, Graham K Packham, PhD, Andrew J Steele, PhD

Blood (2013) 122 (21): 4125.

https://doi.org/10.1182/blood.V122.21.4125.4125

Published: 2013

NARROW

Targeting CD161 in B-cell malignancies

Selinexor Enhances Natural Killer Cell Function Against Multiple Myeloma Cells

Selinexor Enhances NK Cell Activation Against Lymphoma Cells Via Downregulation of HLA-E

PI3Kδ/AKT Inhibition Augments 2-Phenylethynesulfonamide Induced Apoptosis Via the Unfolded Protein Response in Chronic Lymphocytic Leukemia

Regulation and Impact of BCR Induced Autophagy in Chronic Lymphocytic Leukemia

Releasing the brakes on BTK-targeting miRNA

Regulation of B-Cell Receptor Signalling By the Tumour Microenvironment in Chronic Lymphocytic Leukemia (CLL) and Its Impact on Adhesion and miRNA Expression

To BH3 profile or not to BH3 profile

IL-4 enhances expression and function of surface IgM in CLL cells

Biological Significance of B Cell Receptor Mediated Regulation of Autophagy in Chronic Lymphocytic Leukemia

The Syk\Jak Inhibitor Cerdulatinib (PRT062070) Shows Promising Preclinical Activity in Chronic Lymphocytic Leukemia By Antagonising B Cell Receptor and Microenvironmental Signalling

The PI3K/mTOR inhibitor PF-04691502 induces apoptosis and inhibits microenvironmental signaling in CLL and the Eµ-TCL1 mouse model

The Dual PI3K/mTOR Inhibitor PF-04691502 Induces Substantial Apoptosis in Chronic Lymphocytic Leukemia Cells in Vitro and Prolongs Survival in the Eµ-TCL1 Mouse Model

IL-4 Exerts Opposing Effects on Surface-IgM and CXCR4 Mediated Signalling in Chronic Lymphocytic Leukaemia

Modulation of B Cell Receptor Signalling By IL-4 In Chronic Lymphocytic Leukaemia

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American Society of Hematology

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American Society of Hematology

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