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Journal Articles

Loss of De Novo DNA Methyltransferase DNMT3A Impacts Alternative Splicing in Hematopoietic Stem Cells

Raghav Ramabadran, BS, Jarey Wang, Anna Guzman, Sean Michael Cullen, MD PhD, Lorenzo Brunetti, MD, Michael Gundry, Sunny Chan, PhD, Michael Kyba, PhD, Thomas Westbrook, PhD, Margaret Goodell, PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 1.
https://doi.org/10.1182/blood.V130.Suppl_1.1.1
Published: 2017
Journal Articles

HoxA3 Controls Notch Pathway to Repress Blood Development

Valentina Sanghez, PhD, Dustin Kee, Steven Beuder, Danielle Rux, Mitsujiro Osawa, PhD, Joe Markson, PhD, Michael Elowitz, PhD, Michael Kyba, PhD, Michelina Iacovino, PhD
Journal: Blood
Blood (2014) 124 (21): 4338.
https://doi.org/10.1182/blood.V124.21.4338.4338
Published: 2014
Journal Articles

Conditional Expression of a Leukemogenic Fusion Oncogene in Murine Hematopoietic Stem Cells Results in Highly Invasive AML with Origin-Related Genetic Signatures of Prognostic Significance for the Human Disease

Vaia Stavropoulou, PhD, Susanne Kaspar, Laurent Brault, PhD, Sabine Juge, Alexander Tzankov, MD PhD, Mathijs A. Sanders, MSc, Michael Kyba, PhD, Peter J.M. Valk, PhD, Antoine H.F.M. Peters, PhD, Juerg Schwaller, MD
Journal: Blood
Blood (2014) 124 (21): 779.
https://doi.org/10.1182/blood.V124.21.779.779
Published: 2014
Journal Articles

Inducible Gata1 Suppression As a Novel Strategy to Expand Physiologic Megakaryocyte Production from Embryonic Stem Cells

Ji-Yoon Noh, PhD, Shilpa Gandre-Babbe, PhD, Yuhuan Wang, PhD, Vincent Hayes, BS, Yu Yao, Paul Gadue, PhD, Spencer Sullivan, MD, Stella T. Chou, MD, Vikram R Paralkar, MD, Kellie R Machlus, PhD, Joseph E. Italiano, PhD, Michael Kyba, PhD, Deborah L. French, PhD, Mortimer Poncz, MD, Mitchell J. Weiss, MD PhD
Journal: Blood
Blood (2014) 124 (21): 3846.
https://doi.org/10.1182/blood.V124.21.3846.3846
Published: 2014
Journal Articles

A Novel Conditional Mouse Model For MLL-ENL Induced Acute Leukemia

Vaia Stavropoulou, PhD, Sabine Juge, Alexander Tzankov, MD, PhD, Michael Kyba, PhD, Antoine H.F.M. Peters, PhD, Juerg Schwaller, MD
Journal: Blood
Blood (2013) 122 (21): 1277.
https://doi.org/10.1182/blood.V122.21.1277.1277
Published: 2013
Journal Articles

Cellular and Molecular Targets of MLL-AF9 in a Novel Conditional Mouse Model

Vaia Stavropoulou, PhD, Susanne Kaspar, Laurent Brault, PhD, Sabine Juge, Stefano Morettini, PhD, Alexander Tzankov, MD, Michael Kyba, PhD, Antoine H.F.M. Peters, PhD, Juerg Schwaller, MD
Journal: Blood
Blood (2012) 120 (21): 1280.
https://doi.org/10.1182/blood.V120.21.1280.1280
Published: 2012
Journal Articles

DNA Methylation Profile of Runx1 Regulatory Regions Is Correlated with Transition From Primitive to Definitive Hematopoietic Potential In Vitro and In Vivo

Beau Webber, Michelina Iacovino, Michael Kyba, PhD, Bruce R. Blazar, MD, Jakub Tolar, MD, PhD
Journal: Blood
Blood (2011) 118 (21): 389.
https://doi.org/10.1182/blood.V118.21.389.389
Published: 2011
Journal Articles

Modeling Megakaryopoiesis and Leukemogenesis Using Human and Murine Embryonic Stem Cells

Stephanie Ann Massaro, MD, MPH, Elenoe C Smith, Michelina Iacovino, PhD, Michael Kyba, PhD, Diane Krause, MD, PhD
Journal: Blood
Blood (2010) 116 (21): 2502.
https://doi.org/10.1182/blood.V116.21.2502.2502
Published: 2010
Journal Articles

HoxA2 Regulates Proliferation of an Embryonic Megakaryocyte Progenitor, Which Can Effectively Produce Platelets In Vitro .

Michelina Iacovino, PhD, Mitsujiro Osawa, PhD, Zhaohui Xu, Melissa G. Prather, Michael Kyba, PhD
Journal: Blood
Blood (2007) 110 (11): 1266.
https://doi.org/10.1182/blood.V110.11.1266.1266
Published: 2007
Journal Articles

Transgenes Targeted to the HPRT Locus and Expressed from a Tetracycline-Inducible Promoter Are Silenced during Embryonic Stem Cell Differentiation.

Laurie A. Milner, MD, Michael Kyba, PhD, George Q. Daley, MD, PhD, Marlene Balys, MS
Journal: Blood
Blood (2005) 106 (11): 3618.
https://doi.org/10.1182/blood.V106.11.3618.3618
Published: 2005