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Michael L Wang, MD
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Journal Articles

Clinical and Radiological Correlates of Neurotoxicity after Standard of Care Axicabtagene Ciloleucel in Patients with Relapsed/Refractory Large B-Cell Lymphoma

Paolo Strati, MD, Sudhakar Tummala, Loretta J. Nastoupil, MD MSc, Jason R. Westin, MD, Luis Fayad, MD, Sairah Ahmed, MD, Nathan H. Fowler, MD, F. B. Hagemeister, MD, Hun Ju Lee, MD, Swaminathan P. Iyer, MD, Ranjit Nair, MD, Simrit Parmar, MBBS, Maria Alma Rodriguez, MD, Felipe Samaniego, MD, Raphael Eric Steiner, MD, Michael L. Wang, MD, Chelsea Camille Pinnix, MD PhD, Sherry Adkins, ANP, Catherine M. Claussen, MS, Charles Martinez, Misha Hawkins, Nicole Johnson, Shirley George, Sattva S Neelapu, MD, Linda Chi, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 765.
https://doi.org/10.1182/blood-2019-125769
Published: 2019
Journal Articles

Non-Bcl2 Mutations Are Predominant in Patients (pts) with Venetoclax Resistant Mantle Cell Lymphoma (MCL) - Response and Clinical Outcomes in Ultra-Refractory MCL

Preetesh Jain, MBBS,MDDM,PhD, Shuangtao Zhao, PhD, Rashmi Kanagal-Shamanna, MD, Lucy Navsaria, MB BCh BAO, Holly Hill, Ankita Misra, Krystle Nomie, PhD, Changying Jiang, PhD, Yixin Yao, PhD, Liang Zhang, MD PhD, Loretta J. Nastoupil, MD MSc, F. B. Hagemeister, MD, Jason R. Westin, MD, Ranjit Nair, MD, Raphael Eric Steiner, MD, Onyeka Oriabure, Wendy Chen, Guilin Tang, MD, C. Cameron Yin, MD PhD, Keyur Patel, MD PhD, Jorge Enrique Romaguera, MD, Nathan H. Fowler, MD, Linghua Wang, PhD, Michael L. Wang, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2815.
https://doi.org/10.1182/blood-2019-126175
Published: 2019
Journal Articles

BI-1206, a Monoclonal Antibody Against Fcγriib, Showed Superior Anti-Tumor Activity in an Ibrutinib-Venetoclax Dual Resistant PDX Model in Mantle Cell Lymphoma

Changying Jiang, PhD, Yang Liu, MD, Joseph Mitchell McIntosh, Angela Leeming, Rongjia Zhang, William Lee, Krystle Nomie, PhD, Ingrid Karlsson, PhD, Linda Mårtensson, PhD, Mathilda Kovacek, Ingrid Teige, PhD, Björn Frendéus, PhD, Michael L. Wang, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2863.
https://doi.org/10.1182/blood-2019-126957
Published: 2019
Journal Articles

Results of a Phase II Study of Obinutuzumab in Combination with Lenalidomide in Previously Untreated, High Tumor Burden Follicular Lymphoma (FL)

Loretta J. Nastoupil, MD MSc, Jason R. Westin, MD, Fredrick B. Hagemeister, MD, Hun Ju Lee, Luis Fayad, MD, Felipe Samaniego, MD, Sairah Ahmed, MD, Linda Claret, Raphael E Steiner, MD, Ranjit Nair, MBBS,MD, Simrit Parmar, MBBS, Maria Alma Rodriguez, MD, Michael L. Wang, MD, Michael R Green, PhD, Eric Davis, MD, Sattva S Neelapu, MD, Nathan H Fowler, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 125.
https://doi.org/10.1182/blood-2019-129422
Published: 2019
Journal Articles

Results from a First-in-Human, Proof-of-Concept Phase 1 Trial in Pretreated B-Cell Malignancies for Loxo-305, a Next-Generation, Highly Selective, Non-Covalent BTK Inhibitor

Anthony R. Mato, MDMSCE, Ian W. Flinn, MD PhD, John M. Pagel, MD PhD DSc, Jennifer R. Brown, MD PhD, Chan Y. Cheah, Catherine C. Coombs, MD, Manish R. Patel, MD, S. Michael Rothenberg, MD PhD, Donald E. Tsai, MD PhD, Nora C. Ku, MD, Michael L. Wang, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 501.
https://doi.org/10.1182/blood-2019-127509
Published: 2019
Journal Articles

Consensus and Divergence in Practice Patterns Among Experts and Community Healthcare Providers for the Treatment of Patients with Mantle Cell Lymphoma

Kristen M Rosenthal, PhD, Stephen M Ansell, MD PhD, John P. Leonard, MD, Julie M Vose, MDMBA, Michael L. Wang, MD, Timothy A Quill, PhD, Kevin L Obholz, PhD, Christopher R. Flowers, MD MS
Journal: Blood
Blood (2019) 134 (Supplement_1): 410.
https://doi.org/10.1182/blood-2019-124519
Published: 2019
Journal Articles

Pivotal Safety and Efficacy Results from Transcend NHL 001, a Multicenter Phase 1 Study of Lisocabtagene Maraleucel (liso-cel) in Relapsed/Refractory (R/R) Large B Cell Lymphomas

Jeremy S. Abramson, MD MMSc, Maria Lia Palomba, MD, Leo I. Gordon, MD, Matthew A. Lunning, DO, FACP, Michael L. Wang, MD, Jon E. Arnason, MD, Amitkumar Mehta, MD, Enkhtsetseg Purev, MD PhD, David G. Maloney, MD PhD, Charalambos Andreadis, MD MSCE, Alison R. Sehgal, MD, Scott R. Solomon, MD, Nilanjan Ghosh, MD PhD, Tina Albertson, MD, Jacob Garcia, MD, Ana Kostic, Daniel Li, PhD, Yeonhee Kim, Tanya Siddiqi, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 241.
https://doi.org/10.1182/blood-2019-127508
Published: 2019
Journal Articles

Genetically Defined Metabolic Targets Overcome Ibrutinib Resistance in Mantle Cell Lymphoma

Liang Zhang, MD PhD, Hui Guo, PhD, Hui Zhang, Yixin Yao, PhD, Yang Liu, MD, Shaojun Zhang, PhD, Lixin Rui, PhD, Linghua Wang, PhD, Krystle Nomie, PhD, Michael L. Wang, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 395.
https://doi.org/10.1182/blood-2019-125934
Published: 2019
Journal Articles

Targeting PI3K and PLK1 to Overcome Ibrutinib-Venetoclax Resistance in Mantle Cell Lymphoma

Changying Jiang, PhD, Rongjia Zhang, Shaojun Zhang, PhD, William Lee, Shengjian Huang, PhD, Yang Liu, MD, Angela Leeming, Joseph Mitchell McIntosh, Preetesh Jain, MBBS,MDDM,PhD, Krystle Nomie, PhD, Linghua Wang, PhD, Michael L. Wang, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 4062.
https://doi.org/10.1182/blood-2019-128299
Published: 2019
Journal Articles

Overall Survival, Adverse Events, and Economic Burden in Medicare-Insured Patients with Mantle Cell Lymphoma Receiving Cancer-Directed Therapy

Shaum M Kabadi, PhD MPH, Ravi K Goyal, MS, Saurabh P Nagar, MS, Keith L Davis, MA, Hannah Le, PharmD, MPH, Xianglin L Du, MB, MS, PhD, Preetesh Jain, MBBS,MDDM,PhD, Michael L. Wang, MD, Jorge Enrique Romaguera, MD, James A Kaye, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 63.
https://doi.org/10.1182/blood-2019-122841
Published: 2019
Journal Articles

Frontline Treatment with Ibrutinib Plus Rituximab (IR) Followed By Short Course R-Hypercvad/MTX Is Extremely Potent and Safe in Patients (age ≤ 65 years) with Mantle Cell Lymphoma (MCL) - Results of Phase-II Window-1 Clinical Trial

Michael L. Wang, MD, Preetesh Jain, MBBS,MDDM,PhD, Hun Ju Lee, MD, F. B. Hagemeister, MD, Felipe Samaniego, MD, Jason R. Westin, MD, Loretta J. Nastoupil, MD MSc, Wendy Chen, Krystle Nomie, PhD, Shaojun Zhang, PhD, Omar Moghrabi, Shuangtao Zhao, PhD, Rashmi Kanagal-Shamanna, MD, Chi Young Ok, MD, Onyeka Oriabure, Graciela M. Nogueras González, MPH, Dayoung Jung, Lucy Navsaria, MB BCh BAO, Ann Uy, Archie Pedersen, Liang Zhang, MD PhD, Changying Jiang, PhD, Feng Lei, MS, Yixin Yao, PhD, Guofang Xu, MD, Nicolaus Wagner-Bartak, MD, Selvi Thirumurthi, David Santos, Guilin Tang, MD, Keyur Patel, MD PhD, C. Cameron Yin, MD PhD, Michelle Avellaneda, Maria Badillo, Luis Fayad, MD, Sattva S Neelapu, MD, Nathan H. Fowler, MD, Jorge Enrique Romaguera, MD, Linghua Wang, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3987.
https://doi.org/10.1182/blood-2019-126044
Published: 2019
Journal Articles

Frontline Treatment with Ibrutinib with Rituximab (IR) Combination Is Highly Effective in Elderly (≥65 years) Patients with Mantle Cell Lymphoma (MCL) - Results from a Phase II Trial

Preetesh Jain, MBBS,MDDM,PhD, Hun Ju Lee, MD, Raphael Eric Steiner, MD, F. B. Hagemeister, MD, Felipe Samaniego, MD, Jason R. Westin, MD, Loretta J. Nastoupil, MD MSc, Sairah Ahmed, MD, Swaminathan P. Iyer, MD, Jorge Enrique Romaguera, MD, Shuangtao Zhao, PhD, Krystle Nomie, PhD, Chi Young Ok, MD, Rashmi Kanagal-Shamanna, MD, Onyeka Oriabure, Guofang Xu, MD, Liang Zhang, MD PhD, Changying Jiang, PhD, Dayoung Jung, Lucy Navsaria, MB BCh BAO, Wendy Chen, Omar Moghrabi, Tayyaba Nizam, Chloe Marie McClain, Maria Badillo, Selvi Thirumurthi, David Santos, Guilin Tang, MD, Keyur Patel, MD PhD, Sattva S Neelapu, MD, Linghua Wang, PhD, Nathan H. Fowler, MD, Michael L. Wang, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3988.
https://doi.org/10.1182/blood-2019-125800
Published: 2019
Journal Articles

Transcriptomic Heterogeneity and Clonal Evolution Associated with Therapeutic Resistance in Mantle Cell Lymphoma Revealed By Single Cell RNA-Seq

Changying Jiang, PhD, Shaojun Zhang, PhD, Yuanxin Wang, Rongjia Zhang, Yang Liu, MD, Joseph Mitchell McIntosh, Guangchun Han, PhD, Ruiping Wang, PhD, David Santos, Maria Badillo, Angela Leeming, Zhihong Chen, Kimberly Hartig, John Bigcal, Hun Ju Lee, Raphael E Steiner, MD, Jorge Enrique Romaguera, MD, Preetesh Jain, MBBS, MDDM, PhD, Krystle Nomie, PhD, Andy Futreal, PhD, Linghua Wang, PhD, Michael L. Wang, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 5217.
https://doi.org/10.1182/blood-2019-129134
Published: 2019
Journal Articles

A Prospective Disease Registry of Patients with Mantle Cell Lymphoma Treated with Novel Agents: Treatment Patterns, Outcomes, and Patient-Reported Health-Related Quality of Life

Chaitra Ujjani, MD, Anthony R. Mato, MDMSCE, Jonathon B. Cohen, MDMS, Jakub Svoboda, MD, David Andorsky, MD, Andre Goy, MD, Michael L. Wang, MD, Anita Kumar, MD, Peggy Ann Torney, MS, Michelle Dawson, PhD, Cynthia Elesinmogun, PharmD, Shaum M Kabadi, PhDMPH, Brian Seal, MBA, PhD, John M. Pagel, MD PhD DSc, Scott D Ramsey, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 5892.
https://doi.org/10.1182/blood-2019-122845
Published: 2019
Journal Articles

Pdox Models Empower Preclinical Drug Evaluation and Mechanistic Studies Via Faithful Recapitulation of the Pathology, Complex Heterogeneity, Genetic-Transcriptomic Landscape, and Therapeutic Response of Mantle Cell Lymphoma

Changying Jiang, PhD, Shaojun Zhang, PhD, Shengjian Huang, PhD, Yang Liu, MD, Rongjia Zhang, Angela Leeming, Joseph Mitchell McIntosh, William Lee, Krystle Nomie, PhD, Linghua Wang, PhD, Michael L. Wang, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3974.
https://doi.org/10.1182/blood-2019-128810
Published: 2019
Journal Articles

Analysis of Factors Predictive of Risk of Transformation and Time to Transformation in Patients (pts) with Mantle Cell Lymphoma - Cohort Study of 369 Patients

Preetesh Jain, MBBS,MDDM,PhD, Rashmi Kanagal-Shamanna, MD, Chi Young Ok, MD, Gonzalez-Pagan Omarya, Lucy Navsaria, MB BCh BAO, Graciela M. Nogueras González, MPH, Shaojun Zhang, PhD, Guangchun Han, Ahmad Ghorab, Prajwal Boddu, MD, F. B. Hagemeister, MD, Hun Ju Lee, MD, Krystle Nomie, PhD, Changying Jiang, PhD, Luis Fayad, MD, Jason R. Westin, MD, Loretta J. Nastoupil, MD MSc, Sairah Ahmed, MD, Swaminathan P. Iyer, MD, Richard E. Champlin, MD, Sattva S Neelapu, MD, Jorge Enrique Romaguera, MD, Nathan H. Fowler, MD, Guilin Tang, MD, Shaoying Li, MD, Keyur Patel, MD PhD, Selvi Thirumurthi, Pan Tinsu, Guofang Xu, MD, Linghua Wang, PhD, Michael L. Wang, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1526.
https://doi.org/10.1182/blood-2019-125936
Published: 2019
Journal Articles

Predictive Factors of Response and Survival of Lenalidomide and Rituximab As Initial Treatment of Follicular Lymphoma

Paolo Strati, MD, Ralph J. Johnson, PhD, Sheryl G Forbes, Loretta J. Nastoupil, MD MSc, Felipe Samaniego, MD, Eric Davis, MD, Michael R Green, PhD, Luis Fayad, MD, F. B. Hagemeister, MD, Jason R. Westin, MD, Michael L. Wang, MD, Sattva S Neelapu, MD, Nathan H Fowler, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1533.
https://doi.org/10.1182/blood-2019-129311
Published: 2019
Journal Articles

Identify AMPK-Mediated Autophagy and Oxphos As a Novel Metabolic Vulnerability for Targeted Therapy in Mantle Cell Lymphoma

Yixin Yao, PhD, Yang Liu, MD, Hui Zhang, Angela Leeming, Joseph Mitchell McIntosh, Preetesh Jain, MBBS,MDDM,PhD, Liang Zhang, MD PhD, Krystle Nomie, PhD, Michael L. Wang, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1506.
https://doi.org/10.1182/blood-2019-126738
Published: 2019
Journal Articles

Long-Term Outcomes with Ibrutinib Versus the Prior Regimen: A Pooled Analysis in Relapsed/Refractory (R/R) Mantle Cell Lymphoma (MCL) with up to 7.5 Years of Extended Follow-up

Simon Rule, Martin H. Dreyling, MD PhD, Andre Goy, MD, Georg Hess, Rebecca Auer, MRCP, FRPath, PhD, Brad S. Kahl, MD, Jose Angel Hernandez-Rivas, MD PhD, Keqin Qi, PhD, Sanjay Deshpande, Lori Parisi, Michael L. Wang, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1538.
https://doi.org/10.1182/blood-2019-124691
Published: 2019
Journal Articles

KTE-X19, an Anti-CD19 Chimeric Antigen Receptor (CAR) T Cell Therapy, in Patients (Pts) With Relapsed/Refractory (R/R) Mantle Cell Lymphoma (MCL): Results of the Phase 2 ZUMA-2 Study

Michael L. Wang, MD, Javier Munoz, MD, Andre Goy, MD, Frederick L. Locke, MD, Caron A. Jacobson, MD MMSc, Brian T. Hill, MD, John M. Timmerman, MD, Houston Holmes, MD, Samantha Jaglowski, MDMPH, Ian W. Flinn, MD PhD, Peter A. McSweeney, MD, David B. Miklos, MD PhD, John M. Pagel, MD PhD DSc, Marie Jose Kersten, MD PhD, Weimin Peng, MS, Lianqing Zheng, PhD, John M. Rossi, MS, Rajul K. Jain, MD, Arati V. Rao, MD, Patrick M Reagan, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 754.
https://doi.org/10.1182/blood-2019-126064
Published: 2019