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Naoshi Sugimoto
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Journal Articles

iPLAT1: the first-in-human clinical trial of iPSC-derived platelets as a phase 1 autologous transfusion study

Clinical Trials & Observations
Naoshi Sugimoto, Junya Kanda, Sou Nakamura, Toshiyuki Kitano, Masakatsu Hishizawa, Tadakazu Kondo, Shin Shimizu, Akiko Shigemasa, Hideyo Hirai, Yasuyuki Arai, Manabu Minami, Harue Tada, Dai Momose, Ki-Ryang Koh, Masayuki Nogawa, Naohide Watanabe, Shinichiro Okamoto, Makoto Handa, Akira Sawaguchi, Nobuki Matsuyama, Mitsunobu Tanaka, Tomoya Hayashi, Akihiro Fuchizaki, Yoshihiko Tani, Akifumi Takaori-Kondo, Koji Eto
Journal: Blood
Blood (2022) 140 (22): 2398–2402.
https://doi.org/10.1182/blood.2022017296
Published: 2022
Includes: Supplemental data
Journal Articles

The First-in-Human Clinical Trial of iPSC-Derived Platelets (iPLAT1): Autologous Transfusion to an Aplastic Anemia Patient with Alloimmune Platelet Transfusion Refractoriness

Naoshi Sugimoto, Junya Kanda, Sou Nakamura, Toshiyuki Kitano, Masakatsu Hishizawa, Tadakazu Kondo, Shin Shimizu, Akiko Shigemasa, Hideyo Hirai, Harue Tada, Manabu Minami, Naohide Watanabe, Masayuki Nogawa, Makoto Handa, Yoshihiko Tani, Akifumi Takaori-Kondo, Koji Eto
Journal: Blood
Blood (2021) 138 (Supplement 1): 351.
https://doi.org/10.1182/blood-2021-145814
Published: 2021
Journal Articles

Oncolytic Virus Therapy with HSV-1 for Hematologic Malignancies

Ryo Ishino, Yumi Kawase, MD, Toshio Kitawaki, MD PhD, Naoshi Sugimoto, MD PhD, Maki Oku, MD, Shumpei Uchida, MD, Osamu Imataki, MD PhD, Akihito Matsuoka, MD PhD, Teruhisa Taoka, MD PhD, Kimihiro Kawakami, MD PhD, Tomoki Todo, MD PhD, Akifumi Takaori-Kondo, MD PhD, Norimitsu Kadowaki, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3242.
https://doi.org/10.1182/blood-2019-127754
Published: 2019
Journal Articles

α IIb β 3 changes gears in MKs and platelets

Naoshi Sugimoto, Koji Eto
Journal: Blood
Blood (2019) 133 (16): 1700–1701.
https://doi.org/10.1182/blood-2019-01-896092
Published: 2019
Journal Articles

Environmental Cell-Matrix Adhesion Modulates Pluripotent Stem Cell Fate Toward Definitive Hemogenic Endothelium and Hematopoietic Progenitor Cells

Akinori Yuzuriha, Sou Nakamura, PhD, Toshie Kusunoki, Takuya Matsumoto, PhD, Naoshi Sugimoto, MD PhD, Kiyotoshi Sekiguchi, PhD, Koji Eto, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 3845.
https://doi.org/10.1182/blood-2018-99-114505
Published: 2018
Journal Articles

Diagnostic Value of Flow Cytometry Technique By European Leukemianet for Idiopathic Cytopenia of Undetermined Significance

Shumpei Uchida, MD, Osamu Imataki, MD, Hiroyuki Kubo, MD, Shigeyuki Yokokura, MD PhD, Makiko Uemura, MD, Naoshi Sugimoto, MD PhD, Norimitsu Kadowaki, MD PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 1707.
https://doi.org/10.1182/blood.V130.Suppl_1.1707.1707
Published: 2017
Journal Articles

Clonal and Non-Clonal Chromosomal Aberrations in Cytopenic Patients without Hematological Malignancies

Shumpei Uchida, MD, Osamu Imataki, MD, Hiroyuki Kubo, MD, Shigeyuki Yokokura, MD PhD, Makiko Uemura, MD, Naoshi Sugimoto, Norimitsu Kadowaki, MD PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 5319.
https://doi.org/10.1182/blood.V130.Suppl_1.5319.5319
Published: 2017
Journal Articles

Synthetic miRNA Switch Technology Elucidates Heterogeneity in Regulation of Immortalized Megakaryocyte Cell Lines, Associated with Improvement of Platelet Generation Efficiency for Clinical Use

Kazuya Hashimoto, Satoshi Matsuura, Yoshihiko Fujita, Karin Hayashi, Naoshi Sugimoto, MD PhD, Takuya Yamamoto, Hirohide Saito, Koji Eto, MD PhD
Journal: Blood
Blood (2016) 128 (22): 3867.
https://doi.org/10.1182/blood.V128.22.3867.3867
Published: 2016
Journal Articles

Natural Killer Cell Activities Against iPSCs-Derived HLA-Knockout Platelets and Megakaryocytes Reveal Perfect Rejection Profiles for Allotransfusion

Daisuke Suzuki, Naoshi Sugimoto, MD PhD, Norihide Yoshikawa, Hiroshi Endo, Sou Nakamura, Akitsu Hotta, Koji Eto, MD PhD
Journal: Blood
Blood (2016) 128 (22): 3841.
https://doi.org/10.1182/blood.V128.22.3841.3841
Published: 2016
Journal Articles

High-Vorticity with Periodic Flow Enhances in Vitro Biogenesis of Healthy Platelets from iPSC-Derived-Megakaryocytes

Yukitaka Ito, Sou Nakamura, Tomohiro Shigemori, Naoshi Sugimoto, MD PhD, Yoshikazu Kato, Kazuya Hashimoto, Naohide Watanabe, Masayuki Nogawa, Makoto Handa, Satoshi Nishimura, Koji Eto
Journal: Blood
Blood (2016) 128 (22): 2181.
https://doi.org/10.1182/blood.V128.22.2181.2181
Published: 2016
Journal Articles

Expansion of Dysfunctional CD56-Negative NK Cells Is a Hallmark of NK Cell Activation in Ph + Leukemia Patients Treated with Dasatinib

Ken-ichi Ishiyama, MD, Toshio Kitawaki, MD PhD, Naoshi Sugimoto, MD PhD, Akifumi Takaori-Kondo, MD PhD, Norimitsu Kadowaki, MD PhD
Journal: Blood
Blood (2016) 128 (22): 1904.
https://doi.org/10.1182/blood.V128.22.1904.1904
Published: 2016
Journal Articles

DUSP4 Stabilizes FOXP3 Expression In Human Regulatory T Cells

Naoshi Sugimoto, MD, PhD, Yong-Jun Liu, MD, PhD
Journal: Blood
Blood (2013) 122 (21): 3473.
https://doi.org/10.1182/blood.V122.21.3473.3473
Published: 2013