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Nicolás Di Siervi
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Journal Articles

CDK7 enables adaptive gene transcription required by stromal cells to support distinct T-cell lymphoma phenotypes and represents a novel microenvironment-directed therapeutic target

Free
Khouloud Kouidri, Danilo Fiore, María Revuelta, Nicolás Di Siervi, Federico Ruiz Moreno, Subhashini Joshi, Clarisse Kayembe, Abigail Taylor, Giorgio Inghirami, Leandro Cerchietti, Nahuel Zamponi
Journal: Blood
Blood (2025) 146 (Supplement 1): 554.
https://doi.org/10.1182/blood-2025-554
Published: 2025
Journal Articles

Humanized PDX models reveal Lymphoma–Host interactions and enhanced T-cell therapies via epigenetic modulation

Free
Giovanni Medico, Giorgia Zanetti, Giorgio Bertolazzi, Francesco Vallania, Paul Zumbo, Maider Amiama, Doron Betel, Maria Cacciapuoti, Abigail Taylor, Clarisse Kayembe, Sanjay Patel, Jennifer Ziello, Arvin Ruiz, Jason Weirather, Gulpreet Kaur, Luca Cappelli, Luca Paruzzo, Marco Ruella, Zhenyuan Dong, Larry Kwak, Nicolás Di Siervi, María Revuelta, Claudio Tripodo, Leandro Cerchietti, Giorgio Inghirami
Journal: Blood
Blood (2025) 146 (Supplement 1): 350.
https://doi.org/10.1182/blood-2025-350
Published: 2025
Journal Articles

Qpctl Inhibition, By Targeting the Inflammatory Tumor Microenvironment, Constitutes a Novel Therapeutic Approach for Diffuse Large B-Cell Lymphoma

Free
Nicolas Di Siervi, Jasper Mullender, María Victoria Revuelta, Nahuel Zamponi, Eloisi Caldas-Lopes, Yusuke Isshiki, Wendy Béguelin, Marcel Scheepstra, Bastiaan Evers, Jens Wuerthner, Leandro Cerchietti
Journal: Blood
Blood (2023) 142 (Supplement 1): 49.
https://doi.org/10.1182/blood-2023-181264
Published: 2023
Journal Articles

FGFR1 Is a Novel Therapeutic Target in Relapsed/Refractory Diffuse Large B Cell Lymphoma (RR-DLBCL)

Free
Nicolas Di Siervi, Maria Victoria Revuelta, Maria Teresa Cacciapuoti, Nahuel Zamponi, Rossella Marullo, Ari Melnick, Giorgio Inghirami, Leandro Cerchietti
Journal: Blood
Blood (2022) 140 (Supplement 1): 1322.
https://doi.org/10.1182/blood-2022-169529
Published: 2022