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Journal Articles

A novel in-frame calreticulin mutation induces activation of JAK-STAT signaling and thrombocytosis

Abigail Runnels, Nicole Arellano, Ling Huang, Saveg Yadav, Maihi Skeen, William Heaton, Cameron Hoppensteadt, Molly Brakhane, Stephen Oh, Shannon Elf

Blood (2025) 146 (Supplement 1): 358.

https://doi.org/10.1182/blood-2025-358

Published: 2025

Journal Articles

Lactate export inhibition reveals a metabolic vulnerability in myelofibrosis

Nathan Krah, Nicole Arellano, William Heaton, Anton Rets, Srinivas Tantravahi, Juliette Pearce, Spencer Gygi, Abigail Runnels, Parker Bowden, Rebekka Schneider, Jared Rutter, Shannon Elf

Blood (2025) 146 (Supplement 1): 357.

https://doi.org/10.1182/blood-2025-357

Published: 2025

Journal Articles

Neutrophil extracellular traps drive myeloproliferation and immune dysfunction in chronic myelomonocytic leukemia

Saveg Yadav, Callie Brown, Mark Cody, Nicole Arellano, Parker Bowden, William Heaton, Maihi Skeen, Abigail Runnels, Cameron Hoppensteadt, Claudia de Araujo, Marco Marchetti, Robert Campbell, Christian Yost, Shannon Elf, Ami Patel

Blood (2025) 146 (Supplement 1): 2057.

https://doi.org/10.1182/blood-2025-2057

Published: 2025

Journal Articles

Glutamine Metabolism Is Altered in Myeloproliferative Neoplasms and Represents a Potential Novel Therapeutic Target

Chad Coen, Jizhi Yan, Caner Saygin, Nicole Arellano, Mirielle Nauman, Katarzyna Zawieracz, Daniele Vanni, Silvia Catricalà, Ilaria Carola Casetti, Oscar Borsani, Elisa Rumi, Daniela Pietra, Shannon Elf, Hunter Blaylock

Blood (2023) 142 (Supplement 1): 6350.

https://doi.org/10.1182/blood-2023-189731

Published: 2023

Journal Articles

BCL-Xl Represents a Novel Therapeutic Target in Type 2 Mutant Calr-Driven Myeloproliferative Neoplasms

Mirielle Nauman, Daniele Vanni, Nicole Arellano, Thao Trang Nguyen, James LaBelle, Caner Saygin, Silvia Catricalà, Ilaria Carola Casetti, Oscar Borsani, Elisa Rumi, Daniela Pietra, Shannon Elf

Blood (2023) 142 (Supplement 1): 3148.

https://doi.org/10.1182/blood-2023-190295

Published: 2023