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Journal Articles

Combination of Ibrutinib and Nivolumab Overcomes Ibrutinib Resistance in a Novel Patient-Derived Mantle Cell Lymphoma 3D Model

Ferran Araujo-Ayala, Cèlia Dobaño-López, Juan G Valero, Ferran Nadeu, Fabien Gava, Carla Faria, Marine Norlund, Renaud Morin, Pascale Bernes-Lasserre, Neus Serrat, Heribert Playa-Albinyana, Rubén Giménez, Elías Campo, Jean Michel Lagarde, Armando López-Guillermo, Eva Giné, Dolors Colomer, Christine Bezombes, Patricia Pérez-Galán

Blood (2022) 140 (Supplement 1): 1323–1324.

https://doi.org/10.1182/blood-2022-163381

Published: 2022

Journal Articles

Co-Transduced CD19/BCMA Dual-Targeting CAR-T Cells for the Treatment of Non-Hodgkin Lymphoma

Mireia Bachiller, Cèlia Dobaño-López, Alba Rodríguez-García, Joan Castellsagué, Marta Gimenez-Alejandre, Asier Antoñana-Vildosola, Beatriz Martin-Antonio, Julio Delgado, Patricia Pérez-Galán, Manel Juan, Álvaro Urbano-Ispizua, Sonia Guedan

Blood (2022) 140 (Supplement 1): 7386–7387.

https://doi.org/10.1182/blood-2022-168651

Published: 2022

Journal Articles

Immunocompetent 3D Follicular Lymphoma Model: A Preclinical Tool to Design Tailored Immunotherapies

Cèlia Dobaño-López, Juan G Valero, Ferran Araujo-Ayala, Ferran Nadeu, Fabien Gava, Carla Faria, Marine Norlund, Renaud Morin, Pascale Bernes-Lasserre, Neus Serrat, Heribert Playa-Albinyana, Andrea Rivero, Pablo Mozas, Elías Campo, Jean-Michel Lagarde, Armando López-Guillermo, Dolors Colomer, Christine Bezombes, Patricia Pérez-Galán

Blood (2022) 140 (Supplement 1): 9279–9280.

https://doi.org/10.1182/blood-2022-166131

Published: 2022

Journal Articles

Mutational Profile and Copy Number Alterations of Follicular Lymphoma Patients with Different Clinical Behavior

Blood (2020) 136 (Supplement 1): 7–8.

https://doi.org/10.1182/blood-2020-140430

Published: 2020

Journal Articles

Boosting Gamma Delta T Cells-Mediated ADCC By PD-1 Blockade in Follicular Lymphoma

Christine Bezombes, PhD, Cédric Rossi, MD, Pauline Gravelle, Julie Bordenave, Emilie Decaup, Mary Poupot, Marie Tosolini, Don-Marc Franchini, Camille Laurent, MD PhD, Renaud Morin, Jean-Michel Lagarde, Loic Ysebaert, MD PhD, Ariel Savina, Christian Klein, PhD, Patricia Perez-Galan, Jean-Jacques Fournié

Blood (2018) 132 (Supplement 1): 5381.

https://doi.org/10.1182/blood-2018-99-112404

Published: 2018

Journal Articles

The BET Inhibitor GS-626510 Converges with Idelalisib through the Inhibition of Tumor-Macrophage Crosstalk and Cytokine Production in Diffuse Large B-Cell Lymphoma

Juan G Valero, PhD, Aranzazu Chamorro-Jorganes, PhD, Katie Walker, PhD, Martina Guerrero-Hernandez, MSc, Vanina Rodriguez, Clara Recasens-Zorzo, MSc, Anna Esteve-Arenys, MSc, Eriong Lee-Verges, MSc, Alba Matas-Cespedes, PhD, Neus Serrat, PhD, Dolors Colomer, PhD, Armando Lopez-Guillermo, Stacey Tannheimer, PhD, Patricia Pérez-Galán, PhD, Gael Roue, PhD

Blood (2017) 130 (Supplement 1): 4108.

https://doi.org/10.1182/blood.V130.Suppl_1.4108.4108

Published: 2017

Journal Articles

Idelalisib Interferes with the Crosstalk of Follicular Lymphoma and Its Immune Microenvironment and Potentiates the Activity of ABT-199

Martina Guerrero-Hernandez, MSc, Alba Matas-Cespedes, PhD, Neus Serrat, PhD, Anella Yahiaoui, BS, Juan G Valero, PhD, Laura Magnano, MD, Alfredo Rivas-Delgado, MD, Dolors Colomer, PhD, Elias Campo, MD PhD, Armando Lopez-Guillermo, Gael Roue, PhD, Stacey Tannheimer, PhD, Patricia Pérez-Galán, PhD

Blood (2017) 130 (Supplement 1): 2813.

https://doi.org/10.1182/blood.V130.Suppl_1.2813.2813

Published: 2017

Journal Articles

BET Bromodomain Blockade Enhances Ikaros Inhibition By Lenalidomide Therapy Providing Additional Activity in I n Vitro and In Vivo Models of Multiple Myeloma

Carlos Fernández de Larrea, Tania Díaz, Vanina Rodriguez, Ester Lozano, Patricia Pérez-Galán, Mari-Pau Mena, Marcos Calderón, Laura Rosiñol, Antonio Martínez, MD PhD, Natalia Tovar, Gael Roue, Joan Bladé

Blood (2016) 128 (22): 308.

https://doi.org/10.1182/blood.V128.22.308.308

Published: 2016

Journal Articles

Daratumumab, a Novel Anti-CD38 Monoclonal Antibody Shows Anti-Tumor Activity in CLL and hampers Leukemia-Microenvironment Interactions

Alba Matas-Céspedes, MS, Anna Vidal-Crespo, MS, Vanina Rodriguez, Julio Delgado, MD PhD, Neus Villamor, MD PhD, Gael Roue, PhD, Elías Campo, MD PhD, Dolors Colomer, PhD, Parul Doshi, PhD, Adrian Wiestner, MD PhD, Paul W.H.I. Parren, PhD, Jeroen Lammerts van Bueren, PhD, Patricia Pérez-Galán, PhD

Blood (2014) 124 (21): 4680.

https://doi.org/10.1182/blood.V124.21.4680.4680

Published: 2014

Journal Articles

Daratumumab, a Novel Human Anti-CD38 Monoclonal antibody shows Anti-Tumor Activity In Mouse Models Of MCL, FL and CLL

Alba Matas-Céspedes, MS, Anna Vidal Crespo, MS, Vanina Rodriguez, Gael Roue, PhD, Armando Lopez-Guillermo, MD, PhD, Elias Campo, MD, PhD, Dolors Colomer, PhD, Jeroen Lammerts van Bueren, PhD, Joost M Bakker, PhD, Adrian Wiestner, MD, PhD, Paul W.H.I. Parren, PhD, Patricia Perez-Galan, PhD

Blood (2013) 122 (21): 378.

https://doi.org/10.1182/blood.V122.21.378.378

Published: 2013

Journal Articles

SOX11 regulates PAX5 expression and blocks terminal B-cell differentiation in aggressive mantle cell lymphoma

Maria Carmela Vegliante, Jara Palomero, Patricia Pérez-Galán, Gaël Roué, Giancarlo Castellano, Alba Navarro, Guillem Clot, Alexandra Moros, Helena Suárez-Cisneros, Sílvia Beà, Luis Hernández, Anna Enjuanes, Pedro Jares, Neus Villamor, Dolors Colomer, José Ignacio Martín-Subero, Elias Campo, Virginia Amador

Blood (2013) 121 (12): 2175–2185.

https://doi.org/10.1182/blood-2012-06-438937

Published: 2013

Includes: Supplemental data

Journal Articles

Phase I Study of On 01910.Na (rigosertib), a Multikinase PI3K Inhibitor in Relapsed/Refractory B-Cell Malignancies

Mark Roschewski, MD, Mohammed Farooqui, DO, Georg Aue, MD, Clifton C. Mo, MD, Janet Valdez, PA, Susan Soto, RN, Patricia Perez-Galan, PhD, Francois Wilhelm, MD, PhD., Adrian Wiestner, MD, PhD

Blood (2012) 120 (21): 1803.

https://doi.org/10.1182/blood.V120.21.1803.1803

Published: 2012

Journal Articles

The Multi-Kinase Inhibitor Sorafenib Blocks Migration, BCR Survival Signals, Protein Translation and Stroma-Mediated Bortezomib Resistance in Mantle Cell Lymphoma

Silvia Xargay-Torrent, BS, Monica López-Guerra, PhD, Ifigènia Saborit-Villarroya, PhD, Laia Rosich, BS, Alba Navarro, BS, Neus Villamor, MD, PhD, Marta Aymerich, MD, PhD, Patricia Perez-Galan, PhD, Gael Roue, PhD, Elias Campo, MD, PhD, Dolors Colomer, PhD

Blood (2012) 120 (21): 1647.

https://doi.org/10.1182/blood.V120.21.1647.1647

Published: 2012

Journal Articles

Daratumumab, a Novel Human Anti-CD38 Monoclonal Antibody for the Treatment of Chronic Lymphocytic Leukemia and B-Cell Non–Hodgkin Lymphoma

Alba Matas-Céspedes, BS, Anna Vidal-Crespo, BS, Vanina Rodriguez, Gael Roue, PhD, Elias Campo, MD, PhD, Dolors Colomer, PhD, Jeroen Lammerts van Bueren, PhD, Joost M Bakker, PhD, Adrian Wiestner, MD, PhD, Paul W.H.I. Parren, PhD, Patricia Perez-Galan, PhD

Blood (2012) 120 (21): 3935.

https://doi.org/10.1182/blood.V120.21.3935.3935

Published: 2012

Journal Articles

The NSG – Human CLL Xenograft Model Recapitulates the Human Lymph Node Microenvironment in Regards to B-Cell Activation and Tumor Proliferation

Xiameng Sun, BS, Sarah E. M. Herman, PhD, Matthew M. Hsieh, MD, John F. Tisdale, Jichun Chen, PhD, Georg Aue, M.D., Patricia Perez-Galan, PhD, Adrian Wiestner, MD, PhD

Blood (2011) 118 (21): 973.

https://doi.org/10.1182/blood.V118.21.973.973

Published: 2011

Journal Articles

The Bruton Tyrosine Kinase Inhibitor, PCI-32765, Inhibits Activation and Proliferation of Human Chronic Lymphocytic Leukemia Cells in the NSG Xenograph Mouse Model of the Tissue Microenvironment

Sarah E. M. Herman, PhD, Xiameng Sun, BS, Joseph J. Buggy, PhD, Georg Aue, M.D., Patricia Perez-Galan, PhD, Adrian Wiestner, MD, PhD

Blood (2011) 118 (21): 596.

https://doi.org/10.1182/blood.V118.21.596.596

Published: 2011

Journal Articles

The Hsp90 inhibitor IPI-504 overcomes bortezomib resistance in mantle cell lymphoma in vitro and in vivo by down-regulation of the prosurvival ER chaperone BiP/Grp78

Gaël Roué, Patricia Pérez-Galán, Ana Mozos, Mónica López-Guerra, Sílvia Xargay-Torrent, Laia Rosich, Ifigènia Saborit-Villarroya, Emmanuel Normant, Elias Campo, Dolors Colomer

Blood (2011) 117 (4): 1270–1279.

https://doi.org/10.1182/blood-2010-04-278853

Published: 2011

Includes: Supplemental data

Journal Articles

The lymph node microenvironment promotes B-cell receptor signaling, NF-κB activation, and tumor proliferation in chronic lymphocytic leukemia

Blood (2011) 117 (2): 563–574.

https://doi.org/10.1182/blood-2010-05-284984

Published: 2011

Includes: Supplemental data

Journal Articles

Bortezomib resistance in mantle cell lymphoma is associated with plasmacytic differentiation

Patricia Pérez-Galán, Helena Mora-Jensen, Marc A. Weniger, Arthur L. Shaffer, III, Edgar G. Rizzatti, Colby M. Chapman, Clifton C. Mo, Lawrence S. Stennett, Christoph Rader, Poching Liu, Nalini Raghavachari, Maryalice Stetler-Stevenson, Constance Yuan, Stefania Pittaluga, Irina Maric, Kieron M. Dunleavy, Wyndham H. Wilson, Louis M. Staudt, Adrian Wiestner

Blood (2011) 117 (2): 542–552.

https://doi.org/10.1182/blood-2010-02-269514

Published: 2011

Includes: Supplemental data

Journal Articles

Mantle cell lymphoma: biology, pathogenesis, and the molecular basis of treatment in the genomic era

Patricia Pérez-Galán, Martin Dreyling, Adrian Wiestner

Blood (2011) 117 (1): 26–38.

https://doi.org/10.1182/blood-2010-04-189977

Published: 2011

NARROW

Combination of Ibrutinib and Nivolumab Overcomes Ibrutinib Resistance in a Novel Patient-Derived Mantle Cell Lymphoma 3D Model

Co-Transduced CD19/BCMA Dual-Targeting CAR-T Cells for the Treatment of Non-Hodgkin Lymphoma

Immunocompetent 3D Follicular Lymphoma Model: A Preclinical Tool to Design Tailored Immunotherapies

Mutational Profile and Copy Number Alterations of Follicular Lymphoma Patients with Different Clinical Behavior

Boosting Gamma Delta T Cells-Mediated ADCC By PD-1 Blockade in Follicular Lymphoma

The BET Inhibitor GS-626510 Converges with Idelalisib through the Inhibition of Tumor-Macrophage Crosstalk and Cytokine Production in Diffuse Large B-Cell Lymphoma

Idelalisib Interferes with the Crosstalk of Follicular Lymphoma and Its Immune Microenvironment and Potentiates the Activity of ABT-199

BET Bromodomain Blockade Enhances Ikaros Inhibition By Lenalidomide Therapy Providing Additional Activity in I n Vitro and In Vivo Models of Multiple Myeloma

Daratumumab, a Novel Anti-CD38 Monoclonal Antibody Shows Anti-Tumor Activity in CLL and hampers Leukemia-Microenvironment Interactions

Daratumumab, a Novel Human Anti-CD38 Monoclonal antibody shows Anti-Tumor Activity In Mouse Models Of MCL, FL and CLL

SOX11 regulates PAX5 expression and blocks terminal B-cell differentiation in aggressive mantle cell lymphoma

Phase I Study of On 01910.Na (rigosertib), a Multikinase PI3K Inhibitor in Relapsed/Refractory B-Cell Malignancies

The Multi-Kinase Inhibitor Sorafenib Blocks Migration, BCR Survival Signals, Protein Translation and Stroma-Mediated Bortezomib Resistance in Mantle Cell Lymphoma

Daratumumab, a Novel Human Anti-CD38 Monoclonal Antibody for the Treatment of Chronic Lymphocytic Leukemia and B-Cell Non–Hodgkin Lymphoma

The NSG – Human CLL Xenograft Model Recapitulates the Human Lymph Node Microenvironment in Regards to B-Cell Activation and Tumor Proliferation

The Bruton Tyrosine Kinase Inhibitor, PCI-32765, Inhibits Activation and Proliferation of Human Chronic Lymphocytic Leukemia Cells in the NSG Xenograph Mouse Model of the Tissue Microenvironment

The Hsp90 inhibitor IPI-504 overcomes bortezomib resistance in mantle cell lymphoma in vitro and in vivo by down-regulation of the prosurvival ER chaperone BiP/Grp78

The lymph node microenvironment promotes B-cell receptor signaling, NF-κB activation, and tumor proliferation in chronic lymphocytic leukemia

Bortezomib resistance in mantle cell lymphoma is associated with plasmacytic differentiation

Mantle cell lymphoma: biology, pathogenesis, and the molecular basis of treatment in the genomic era

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American Society of Hematology

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American Society of Hematology

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