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Paulette van Strien
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Journal Articles

PML Plays a Key Role in Severe Congenital Neutropenia with Mutant ELANE Causing Neutrophil Elastase Protein Misfolding

Patricia Olofsen, MSc, Paulette van Strien, BSc, Onno Roovers, BSc, Hans De Looper, BSc, Remco Hoogenboezem, MSc, Dennis Bosch, BSc, Mehrnaz Ghazvini, PhD, Eric Bindels, PhD, Emma De Pater, PhD, Ivo Touw, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 213.
https://doi.org/10.1182/blood-2019-122423
Published: 2019
Journal Articles

A Leukemic Progression Model of Severe Congenital Neutropenia Uncovers a Novel Mechanism of AML Development Involving Elevated Inflammatory Responses, Mutation of CXXC4 and Decreased TET2 Levels

Patricia Olofsen, MSc, Szabolcs Fatrai, PhD, Paulette van Strien, BSc, Julia Obenauer, MSc, Remco Hoogenboezem, MSc, Claudia Erpelinck-Verschueren, B.Sc., Onno Roovers, BSc, Torsten Haferlach, MD, Peter Valk, PhD, Rebekka Schneider, MDPhD, Emma De Pater, PhD, Ivo Touw, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 540.
https://doi.org/10.1182/blood-2018-99-115914
Published: 2018
Journal Articles

Combinatorial CSF3R and RUNX1 Mutations Involved in the Leukemic Progression of Severe Congenital Neutropenia Confer a G-CSF-Dependent Premalignant State in Mice

Szabolcs Fatrai, PhD, Paulette van Strien, BSc, Julia Obenauer, MSc, BSc, M.M. Van den Heuvel-Eibrink, MD, Ivo Touw, PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 543.
https://doi.org/10.1182/blood.V130.Suppl_1.543.543
Published: 2017
Journal Articles

Multiple Myeloma with a Deletion of Chromosome 17p: TP53 Mutations Are Highly Prevalent and Negatively Affect Prognosis

Davine Hofste op Bruinink, MD MSc, Hoogenboezem Remco, MSc, Mathijs A. Sanders, PhD, Christopher P Wardell, PhD, Cody Ashby, PhD, Eric M.J. Bindels, PhD, Claudia Erpelinck-Verschueren, BSc, Paulette van Strien, BSc, Jasper Koenders, BSc, François G. Kavelaars, BSc, Jie He, PhD, Mark Bailey, MSc, Tariq I Mughal, MD FRCP, Kristine Misund, PhD, Berna Beverloo, PhD, Bronno van der Holt, PhD, Ivo Touw, PhD, Anders Waage, MDPhD, Hervé Avet-Loiseau, MD PhD, Graham H Jackson, MD PhD, Gareth J Morgan, MD PhD, Brian A Walker, PhD, Pieter Sonneveld, MDPhD
Journal: Blood
Blood (2016) 128 (22): 3271.
https://doi.org/10.1182/blood.V128.22.3271.3271
Published: 2016
Journal Articles

A Tissue-Specific Transcriptional Element for C/ebpa Is Required for HSC Maintenance and Neutrophil Development

Roberto Avellino, Marije Havermans, Claudia Erpelinck, Mathijs Sanders, Stefan Groeschel, Harmen Vandewerken, Remco M. Hoogenboezem, M.Sc., Elwin Rombouts, Kirsten Van Lom, Paulette Van Strien, Hans De Looper, Claudia Christine Gebhard, Michael Rehli, Dominik Beck, PhD, Julie A.I. Thoms, PhD, Stefan Erkeland, Ivo Touw, John E. Pimanda, MDPhD, Eric JM Bindels, Ruud Delwel
Journal: Blood
Blood (2015) 126 (23): 301.
https://doi.org/10.1182/blood.V126.23.301.301
Published: 2015
Journal Articles

Lineage-instructive function of C/EBPα in multipotent hematopoietic cells and early thymic progenitors

Albert Wölfler, Astrid A. Danen-van Oorschot, Jurgen R. Haanstra, Marijke Valkhof, Claudia Bodner, Eric Vroegindeweij, Paulette van Strien, Alexandra Novak, Tom Cupedo, Ivo P. Touw
Journal: Blood
Blood (2010) 116 (20): 4116–4125.
https://doi.org/10.1182/blood-2010-03-275404
Published: 2010
Includes: Supplemental data
Journal Articles

Lineage Instructive Function of C/EBPα in Multipotent Hematopoietic Progenitor Cells Revealed in a Novel Cebpa -Cre Knock-in Model

Albert Wolfler, Astrid A Danen-van Oorschot, Jurgen Haanstra, Marijke Valkhof, Paulette van Strien, Elwin Rombouts, Ivo P Touw
Journal: Blood
Blood (2008) 112 (11): 2458.
https://doi.org/10.1182/blood.V112.11.2458.2458
Published: 2008