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Journal Articles

Active STAT3 Prevents Selinexor-Induced Caspase-Independent Apoptosis in Multiple Myeloma

Ryan Michael Mack, Mark Sellin, Stephanie Berg, Rohit Thalla, Kanak Joshi, Lei Zhang, Shanhui Liu, Peter Breslin, Kevin Barton, Patrick Hagen, Jiwang Zhang

Blood (2023) 142 (Supplement 1): 6611.

https://doi.org/10.1182/blood-2023-190030

Published: 2023

Journal Articles

Caspase 8 Deletion Causes Infection/Inflammation-Induced MDS-like Bone Marrow Failure in Mice

Kanak Joshi, Shanhui Liu, Lei Zhang, Ryan Michael Mack, Austin Runde, Patrick Hagen, Kevin Barton, Peter Breslin, Ameet R. Kini, Jiwang Zhang

Blood (2023) 142 (Supplement 1): 1844.

https://doi.org/10.1182/blood-2023-190026

Published: 2023

Journal Articles

Identification of Pre-Gmps and Pre-Meps: Two Novel Types of Committed Progenitor Cells in Bone Marrow

Ryan Mack, Lei Zhang, Kanak Joshi, Shanhui Liu, Mark Sellin, Wei Wei, Peter Breslin, Jiwang Zhang

Blood (2021) 138 (Supplement 1): 3266.

https://doi.org/10.1182/blood-2021-153800

Published: 2021

Journal Articles

Ripk3 Signaling Restricts the Development of Peripheral T Cell Lymphoma in Tet2 Deficient Mice

Kanak Joshi, Ryan Mack, Lei Zhang, Shanhui Liu, Mark Sellin, Wei Wei, Peter Breslin, Ameet R Kini, Jiwang Zhang

Blood (2021) 138 (Supplement 1): 3318.

https://doi.org/10.1182/blood-2021-147896

Published: 2021

Journal Articles

Myc-Miz1 signaling promotes self-renewal of leukemia stem cells by repressing Cebpα and Cebpδ

Lei Zhang, Jing Li, Hui Xu, Xianyu Shao, Li Fu, Ye Hou, Caiqing Hao, Wenyan Li, Kanak Joshi, Wei Wei, Yan Xu, Feng Zhang, Shaojun Dai, Peter Breslin, Jiwang Zhang, Jun Zhang

Blood (2020) 135 (14): 1133–1145.

https://doi.org/10.1182/blood.2019001863

Published: 2020

Includes: Supplemental data

Journal Articles

Ripk3 Signaling Regulates Hematopoietic Stem Cell Number and Function during Stress

Lei Zhang, PhD, Huacheng Luo, PhD, Jing Li, Hong-Min Ni, Mark Sellin, Feng Zhang, Jun Zhang, Peter Breslin, PhD, Wei Wei, William Small, Jr., Wen-Xin Ding, Suming Huang, PhD, Jiwang Zhang, MD

Blood (2019) 134 (Supplement_1): 3714.

https://doi.org/10.1182/blood-2019-131332

Published: 2019

Journal Articles

The Splicing Modulator GEX1A Exhibits Potent Anti-Leukemic Activity Both in Vitro and In Vivo through Inducing an MCL1 Splice-Switch in Pre-Clinical Models of Acute Myeloid Leukemia

Mark Sellin, Ryan Mack, Matthew C. Rhodes, Lei Zhang, PhD, Wei Wei, Peter Breslin, PhD, Stephanie Berg, DO, Suming Huang, PhD, Richard Taylor, PhD, Jiwang Zhang, MD

Blood (2019) 134 (Supplement_1): 2666.

https://doi.org/10.1182/blood-2019-132030

Published: 2019

Journal Articles

Necroptosis of a Small Subset of Hematopoietic Progenitors Induces Autoimmune Bone Marrow Failure

Junping Xin, MD PhD, Ni Allen, Rafael Gutierrez, Haiyan Chen, MDPhD, Jing Li, Joseph Cannova, Grace Ng, Rachel Schmidt, Wei Wei, Peter Breslin, PhD, Paul C Kuo, MD, Patrick J. Stiff, MD, Jiwang Zhang, MD PhD

Blood (2015) 126 (23): 4784.

https://doi.org/10.1182/blood.V126.23.4784.4784

Published: 2015

Journal Articles

Blocking TNF and IL-1 Sensitizes AML Stem Cells to NF-κB Inhibitor Treatment

Volk Andrew, Jing Li, Jun Zhang, PhD, Joseph Cannova, Caiqin Hao, Chenglong Hu, Jiewen Sun, Yan Xu, Wei Wei, Peter Breslin, PhD, Jianjun Chen, PhD, Jiwang Zhang, MD PhD

Blood (2014) 124 (21): 2302.

https://doi.org/10.1182/blood.V124.21.2302.2302

Published: 2014

Journal Articles

Sensitizing Acute Myeloid Leukemia Cells to Interferon-Induced Differentiation By Inhibiting RIP1/RIP3 Necroptotic Pathway

Blood (2014) 124 (21): 3752.

https://doi.org/10.1182/blood.V124.21.3752.3752

Published: 2014

Journal Articles

AML Cells Utilize TNF-Driven JNK Signaling As a Critical NF-κB-Independent Survival Signal

Andrew Volk, Jing Li, PhD, Junping Xin, PhD, Dewen You, PhD, Jun Zhang, PhD, Peter Breslin, PhD, Zejuan Li, MD, PhD, Wei Wei, Rachel Schmidt, Xinyu Li, MD, Zhou Zhang, PhD, Paul C Kuo, MD, Sucha Nand, MD, Jianke Zhang, PhD, Jianjun Chen, PhD, Jiwang Zhang, MD, PhD

Blood (2013) 122 (21): 2890.

https://doi.org/10.1182/blood.V122.21.2890.2890

Published: 2013

Journal Articles

Sensitizing Leukemic Cells to NF-κB Inhibitor Treatment by Repressing TNFα-Mediated, NF-κB-Independent Survival Signaling

Andrew Volk, Yechen Xiao, PhD, Junping Xin, PhD, Dewen You, PhD, Rachel Schmidt, Shubin Zhang, Wei Wei, Peter Breslin, PhD, Sucha Nand, MD, Jiwang Zhang, MD, PhD

Blood (2012) 120 (21): 1878.

https://doi.org/10.1182/blood.V120.21.1878.1878

Published: 2012

Journal Articles

Focal Adhesion Kinase Inactivation Reduces the Development of Acute Leukemia and Partially Rescues Hematopoietic Stem Cell Defects in Pten -Knockout Mice

Dewen You, PhD, Andrew Volk, Clare Sun, MD, Junping Xin, MD, PhD, Geunhyoung Ha, PhD, Chunliu Pan, PhD, Rachel Schmidt, Patience Oladeinde, Wei Wei, Subing Zhang, MD, Eun-Kyoung Breuer, PhD, Peter Breslin, PhD, Jiwang Zhang, MD, PhD

Blood (2012) 120 (21): 864.

https://doi.org/10.1182/blood.V120.21.864.864

Published: 2012

Journal Articles

TNF-α/Fas-RIP-1–induced cell death signaling separates murine hematopoietic stem cells/progenitors into 2 distinct populations

Yechen Xiao, Hongling Li, Jun Zhang, Andrew Volk, Shubin Zhang, Wei Wei, Shanshan Zhang, Peter Breslin, Jiwang Zhang

Blood (2011) 118 (23): 6057–6067.

https://doi.org/10.1182/blood-2011-06-359448

Published: 2011

Includes: Supplemental data

Journal Articles

TNF-α/Fas-RIP-1-Induced Cell Death Signaling Separates Hematopoietic Stem Cells/Progenitors Into Two Distinct Populations

Yechen Xiao, Andrew Volk, Shubin Zhang, Wei Wei, Peter Breslin, Jiwang Zhang

Blood (2011) 118 (21): 393.

https://doi.org/10.1182/blood.V118.21.393.393

Published: 2011

Journal Articles

TNFα-Induced Apoptosis of Hematopoietic Progenitors Is the Major Cause of Bone Marrow Failure Observed In TAK-1 Knockout Mice.

Yechen Xiao, Hongling Li, Peter Breslin, Shubin Zhang, Wei Wei, Penelope Cadigan, Manuel O Diaz, Jiwang Zhang

Blood (2010) 116 (21): 1557.

https://doi.org/10.1182/blood.V116.21.1557.1557

Published: 2010

Journal Articles

An evolutionarily conserved PTEN-C/EBPα-CTNNA1 axis controls myeloid development and transformation

Blood (2010) 115 (23): 4715–4724.

https://doi.org/10.1182/blood-2009-11-255778

Published: 2010

Includes: Supplemental data

Journal Articles

C-Myc Is Required for Acute but Not for Chronic Hematopoietic Malignances in Pten-Null Mice.

Yinshi Guo, MD, PhD, Christopher Seet, MBBS, Chao Niu, MD, PhD, Peter Breslin, PhD, Shubin Zhang, MD, Wei Wei, BS, Manuel Diaz, MD, Patrick Stiff, MD, Jiwang Zhang, MD, PhD

Blood (2009) 114 (22): 1632.

https://doi.org/10.1182/blood.V114.22.1632.1632

Published: 2009

Journal Articles

c-Myc–mediated control of cell fate in megakaryocyte-erythrocyte progenitors

Yinshi Guo, Chao Niu, Peter Breslin, Minghui Tang, Shubin Zhang, Wei Wei, Ameet R. Kini, Gladell P. Paner, Serhan Alkan, Stephan W. Morris, Manuel Diaz, Patrick J. Stiff, Jiwang Zhang

Blood (2009) 114 (10): 2097–2106.

https://doi.org/10.1182/blood-2009-01-197947

Published: 2009

Includes: Supplemental data

Journal Articles

c-Myc is a target of RNA-binding motif protein 15 in the regulation of adult hematopoietic stem cell and megakaryocyte development

Chao Niu, Jiwang Zhang, Peter Breslin, Mihaela Onciu, Zhigui Ma, Stephan Wade Morris

Blood (2009) 114 (10): 2087–2096.

https://doi.org/10.1182/blood-2009-01-197921

Published: 2009

Includes: Supplemental data

NARROW

Active STAT3 Prevents Selinexor-Induced Caspase-Independent Apoptosis in Multiple Myeloma

Caspase 8 Deletion Causes Infection/Inflammation-Induced MDS-like Bone Marrow Failure in Mice

Identification of Pre-Gmps and Pre-Meps: Two Novel Types of Committed Progenitor Cells in Bone Marrow

Ripk3 Signaling Restricts the Development of Peripheral T Cell Lymphoma in Tet2 Deficient Mice

Myc-Miz1 signaling promotes self-renewal of leukemia stem cells by repressing Cebpα and Cebpδ

Ripk3 Signaling Regulates Hematopoietic Stem Cell Number and Function during Stress

The Splicing Modulator GEX1A Exhibits Potent Anti-Leukemic Activity Both in Vitro and In Vivo through Inducing an MCL1 Splice-Switch in Pre-Clinical Models of Acute Myeloid Leukemia

Necroptosis of a Small Subset of Hematopoietic Progenitors Induces Autoimmune Bone Marrow Failure

Blocking TNF and IL-1 Sensitizes AML Stem Cells to NF-κB Inhibitor Treatment

Sensitizing Acute Myeloid Leukemia Cells to Interferon-Induced Differentiation By Inhibiting RIP1/RIP3 Necroptotic Pathway

AML Cells Utilize TNF-Driven JNK Signaling As a Critical NF-κB-Independent Survival Signal

Sensitizing Leukemic Cells to NF-κB Inhibitor Treatment by Repressing TNFα-Mediated, NF-κB-Independent Survival Signaling

Focal Adhesion Kinase Inactivation Reduces the Development of Acute Leukemia and Partially Rescues Hematopoietic Stem Cell Defects in Pten -Knockout Mice

TNF-α/Fas-RIP-1–induced cell death signaling separates murine hematopoietic stem cells/progenitors into 2 distinct populations

TNF-α/Fas-RIP-1-Induced Cell Death Signaling Separates Hematopoietic Stem Cells/Progenitors Into Two Distinct Populations

TNFα-Induced Apoptosis of Hematopoietic Progenitors Is the Major Cause of Bone Marrow Failure Observed In TAK-1 Knockout Mice.

An evolutionarily conserved PTEN-C/EBPα-CTNNA1 axis controls myeloid development and transformation

C-Myc Is Required for Acute but Not for Chronic Hematopoietic Malignances in Pten-Null Mice.

c-Myc–mediated control of cell fate in megakaryocyte-erythrocyte progenitors

c-Myc is a target of RNA-binding motif protein 15 in the regulation of adult hematopoietic stem cell and megakaryocyte development

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American Society of Hematology

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ASH Publications

American Society of Hematology

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