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Journal Articles

Molecular Subgroups of T Cell Acute Lymphoblastic Leukemia in Adults Treated According to GMALL Protocols

Blood (2020) 136 (Supplement 1): 37–38.

https://doi.org/10.1182/blood-2020-141921

Published: 2020

Journal Articles

DNA Methylation Profiling of AML Reveals Epigenetic Subgroups with Distinct Clinical Outcome

Sebastian Vosberg, Paul Kerbs, MSc, Vindi Jurinovic, MSc, Klaus H. Metzeler, MD, Susanne Amler, PhD, Cristina Sauerland, Dennis Görlich, PhD, Wolfgang E. Berdel, MD, Jan Braess, MD, Wolfgang Hiddemann, MD PhD, Karsten Spiekermann, MD, Tobias Herold, MD, Philipp A. Greif, MD PD

Blood (2019) 134 (Supplement_1): 2715.

https://doi.org/10.1182/blood-2019-130047

Published: 2019

Journal Articles

Loss of ZBTB7A Enhances Glycolysis and Beta Oxidation in Myeloid Leukemia

Enric Redondo Monte, MSc, BSc, Anja Wilding, MSc, Georg Leubolt, MSc, Paul Kerbs, MSc, Johannes Bagnoli, Wolfgang Hiddemann, MD PhD, Wolfgang Enard, PhD, Sebastian Theurich, MD, Philipp A. Greif, MD PD

Blood (2019) 134 (Supplement_1): 1453.

https://doi.org/10.1182/blood-2019-128378

Published: 2019

Journal Articles

GATA2 Zinc Finger Mutations Influence Erythroid Differentiation and Chemotherapy Response

Georg Leubolt, MSc, Enric Redondo Monte, MSc, BSc, Anja Wilding, MSc, Paul Kerbs, MSc, Monica Cusan, MD, Johannes Bagnoli, Wolfgang Enard, PhD, Wolfgang Hiddemann, MD PhD, Christian Wichmann, MD, Gunnar Schotta, PhD, Philipp A. Greif, MD PD

Blood (2019) 134 (Supplement_1): 1459.

https://doi.org/10.1182/blood-2019-128218

Published: 2019

Journal Articles

Gene Fusion Detection By RNA-Seq in Acute Myeloid Leukemia (AML)

Paul Kerbs, MSc, Aarif Mohamed Nazeer Batcha, MSc, Sebastian Vosberg, Dirk Metzler, PhD, Tobias Herold, MD, Philipp A. Greif, MD PD

Blood (2019) 134 (Supplement_1): 4655.

https://doi.org/10.1182/blood-2019-125869

Published: 2019

Journal Articles

Loss of ZBTB7A Facilitates RUNX1/RUNX1T1-Dependent Clonal Expansion and Sensitizes for Metabolic Inhibition

Enric Redondo Monte, MSc, BSc, Anja Wilding, MSc, Georg Leubolt, MSc, Luise Hartmann, PhD, Sayantanee Dutta, PhD, Wolfgang Hiddemann, Lingping Chen-Wichmann, PhD, Christian Wichmann, MD, Philipp A. Greif, MD PD

Blood (2018) 132 (Supplement 1): 1499.

https://doi.org/10.1182/blood-2018-99-114789

Published: 2018

Journal Articles

Clonal Evolution of Relapsed CBFB/MYH11 Rearranged Acute Myeloid Leukemia (AML)

Sabrina Opatz, MD, Sebastian Vosberg, Bianka Ksienzyk, Sebastian Tschuri, Alexander Graf, Stefan Krebs, PhD, Helmut Blum, Dr., Stephanie Schneider, PhD, Martin Neumann, Claudia D. Baldus, MD, Christian Thiede, MD, Jan Moritz Middeke, MD, Friedrich Stoelzel, Stefan K. Bohlander, MD, Karsten Spiekermann, MD, Wolfgang Hiddemann, PhD, Klaus H. Metzeler, MD, Philipp A. Greif, MD PD

Blood (2018) 132 (Supplement 1): 2772.

https://doi.org/10.1182/blood-2018-99-115881

Published: 2018

Journal Articles

GATA2 Zinc Finger Mutations Affect DNA-Binding and Promote Granulopoietic Differentiation

Georg Leubolt, MSc, Belay Tizazu, Sayantanee Dutta, PhD, Monica Cusan, MD, Theresa Sippenauer, Rouzanna Istvanffy, PhD, Robert A.J. Oostendorp, PhD, Wolfgang Hiddemann, Philipp A. Greif, MD PD

Blood (2018) 132 (Supplement 1): 2779.

https://doi.org/10.1182/blood-2018-99-115976

Published: 2018

Journal Articles

Homocygous PAX5 Sequence Mutations Define a Novel Subtype of B Cell Precursor Acute Lymphoblastic Leukemia

Blood (2017) 130 (Supplement 1): 2713.

https://doi.org/10.1182/blood.V130.Suppl_1.2713.2713

Published: 2017

Journal Articles

Multi-Omics of Adult T Cell Acute Lymphoblastic Leukemia

Martin Neumann, Michael P Schroeder, PhD, Lorenz Bastian, Jutta Ortiz Tanchez, Cornelia Schlee, Konstandina Isaakidis, Alva Rani James, Lars R. Fransecky, Sebastian Vosberg, Stefan Krebs, PhD, Helmut Blum, PhD, Stefan Schwartz, MD, Thomas Burmeister, Dieter Hoelzer, MD PhD, Philipp A. Greif, MD, Monika Brüggemann, Nicola Goekbuget, MD, Claudia D. Baldus, MD

Blood (2017) 130 (Supplement 1): 2725.

https://doi.org/10.1182/blood.V130.Suppl_1.2725.2725

Published: 2017

Journal Articles

Evolutionary Patterns of Cytogenetically Normal Acute Myeloid Leukemia Correlate with Time to Relapse

Blood (2016) 128 (22): 288.

https://doi.org/10.1182/blood.V128.22.288.288

Published: 2016

Journal Articles

Clones with and without Sensitivity Towards Treatment In Vivo Co-Exist within the Tumor Cells of a Single Patient with ALL

Cornelia Finkenzeller, MSc, Michela Carlet, PhD, Sebastian Vosberg, Christoph Ziegenhain, MSc, Martin Neumann, MD, Kristoffer Riecken, PhD, Kerstin Cornils, PhD, Boris Fehse, PhD, Claudia D. Baldus, MD, Wolfgang Enard, Prof. Dr. rer. nat., Philipp A. Greif, MD, Irmela Jeremias, MD

Blood (2016) 128 (22): 456.

https://doi.org/10.1182/blood.V128.22.456.456

Published: 2016

Journal Articles

Comparison of FLT3-ITD Detection By High-Throughput Amplicon Sequencing to Routine Diagnostics - a Retrospective Analysis of AMLCG Study Patients

Katrin Reiter, MSc, Max Hubmann, MD, Egor Harin, Sebastian Vosberg, Kathrin Bräundl, Bianka Ksienzyk, Stephanie Schneider, PhD, Annika Maria Dufour, PhD, Evelyn Zellmeier, Stefan K. Bohlander, MD, Christina Sauerland, Dipl.-Math, Wolfgang E Berdel, MD, Bernhard J Wörmann, MD, Thomas Büchner, MD, Jan Braess, MD, Wolfgang Hiddemann, MD, Karsten Spiekermann, MD, Philipp A. Greif, MD

Blood (2016) 128 (22): 1682.

https://doi.org/10.1182/blood.V128.22.1682.1682

Published: 2016

Journal Articles

Tyrosin Kinase Inhibition Restores the Membrane Localization of FLT3-ITD

Katrin S. Reiter, Harald Polzer, PhD, Christina Krupka, Binje Vick, PhD, Andreas Maiser, Marion S. Subklewe, MD, Irmela Jeremias, MD, Heinrich Leonhardt, PhD, Karsten Spiekermann, MD, Philipp A. Greif, MD

Blood (2015) 126 (23): 1274.

https://doi.org/10.1182/blood.V126.23.1274.1274

Published: 2015

Journal Articles

Functional Diversity of Single Stem Cell Clones in Patients' Acute Lymphoblastic Leukemia Growing in Mice: An Adverse Subclone with Distinct DNA-Methylation Pattern, Slow Growth In Vivo and Drug Resistance

Cornelia Finkenzeller, M.Sc., Michela Carlet, PhD, Sebastian Vosberg, Philipp A. Greif, MD, Irmela Jeremias, MD

Blood (2015) 126 (23): 3062.

https://doi.org/10.1182/blood.V126.23.3062.3062

Published: 2015

Journal Articles

Molecular Alterations in Refractory Acute Myeloid Leukemia and Persistent Preleukemic Lesions Are Disclosed Using Mesenchymal Stromal Cells As Germline Control

Martin Neumann, MD, Sebastian Vosberg, Eva Kristin Von Der Heide, BSc, Cornelia Schlee, Jutta Ortiz Tanchez, Konstandina Isaakidis, Liliana H. Mochmann, BS,MSc, Lars R. Fransecky, Alexander Graf, PhD, Stefan Krebs, PhD, Helmut Blum, PhD, Philipp A. Greif, MD, Claudia D Baldus, MD

Blood (2015) 126 (23): 3843.

https://doi.org/10.1182/blood.V126.23.3843.3843

Published: 2015

Journal Articles

DNMT3A Mutations Associate with Shorter Survival and Modulate the Prognostic Impact of Mutated NPM1: an Analysis Based on Comprehensive Mutational Screening of 660 AML Patients Treated on German AML Cooperative Group (AMLCG) Trials

Blood (2015) 126 (23): 3815.

https://doi.org/10.1182/blood.V126.23.3815.3815

Published: 2015

Journal Articles

Detection of Chromosomal Aberrations in Acute Myeloid Leukemia By Copy Number Alteration Analysis of Exome Sequencing Data

Sebastian Vosberg, Luise Hartmann, MSc, Stephanie Schneider, PhD, Klaus H. Metzeler, MD, Bianka Ksienzyk, Kathrin Bräundl, Martin Neumann, MD, Claudia D Baldus, MD, Alexander Graf, PhD, Stefan Krebs, PhD, Helmut Blum, PhD, Karsten Spiekermann, MD, Stefan K. Bohlander, MD, Ulrich Mansmann, PhD, Philipp A. Greif, MD

Blood (2015) 126 (23): 3859.

https://doi.org/10.1182/blood.V126.23.3859.3859

Published: 2015

Journal Articles

Mutations of Genes Linked to Epigenetic Regulation Are Frequently Gained in Relapsed Cytogenetically Normal Acute Myeloid Leukemia

Luise Hartmann, MSc, Sebastian Vosberg, Klaus H. Metzeler, MD, Daniela Schumacher, Friederike Pastore, MD, Kathrin Bräundl, Evelyn Zellmeier, Bianka Ksienzyk, Nikola P Konstandin, PhD, Stephanie Schneider, PhD, Stefan Krebs, PhD, Alexander Graf, PhD, Helmut Blum, PhD, Martin Neumann, MD, Claudia D Baldus, MD, Stefan K. Bohlander, MD, Wolfgang Hiddemann, MD, Karsten Spiekermann, MD, Philipp A. Greif, MD

Blood (2015) 126 (23): 690.

https://doi.org/10.1182/blood.V126.23.690.690

Published: 2015

Journal Articles

Targeted, Deep Sequencing of Adult AML Patients Treated on the AMLCG-2008 Trial Detects Clonal Heterogeneity in 52% of Patients at Initial Diagnosis and Reveals Patterns of Clonal Evolution

Maja Rothenberg-Thurley, PhD, Stephanie Schneider, Dr. rer. nat., Tobias Herold, MD, Nikola P Konstandin, Annika Dufour, PhD, Kathrin Bräundl, Bianka Ksienzyk, Evelyn Zellmeier, Philipp A Greif, MD, Michael Fiegl, MD, Marion S. Subklewe, MD, Stefan K Bohlander, MD, Wolfgang Hiddemann, MD, Jan Braess, MD, Karsten Spiekermann, MD, Klaus H. Metzeler, MD

Blood (2014) 124 (21): 697.

https://doi.org/10.1182/blood.V124.21.697.697

Published: 2014

NARROW

Molecular Subgroups of T Cell Acute Lymphoblastic Leukemia in Adults Treated According to GMALL Protocols

DNA Methylation Profiling of AML Reveals Epigenetic Subgroups with Distinct Clinical Outcome

Loss of ZBTB7A Enhances Glycolysis and Beta Oxidation in Myeloid Leukemia

GATA2 Zinc Finger Mutations Influence Erythroid Differentiation and Chemotherapy Response

Gene Fusion Detection By RNA-Seq in Acute Myeloid Leukemia (AML)

Loss of ZBTB7A Facilitates RUNX1/RUNX1T1-Dependent Clonal Expansion and Sensitizes for Metabolic Inhibition

Clonal Evolution of Relapsed CBFB/MYH11 Rearranged Acute Myeloid Leukemia (AML)

GATA2 Zinc Finger Mutations Affect DNA-Binding and Promote Granulopoietic Differentiation

Homocygous PAX5 Sequence Mutations Define a Novel Subtype of B Cell Precursor Acute Lymphoblastic Leukemia

Multi-Omics of Adult T Cell Acute Lymphoblastic Leukemia

Evolutionary Patterns of Cytogenetically Normal Acute Myeloid Leukemia Correlate with Time to Relapse

Clones with and without Sensitivity Towards Treatment In Vivo Co-Exist within the Tumor Cells of a Single Patient with ALL

Comparison of FLT3-ITD Detection By High-Throughput Amplicon Sequencing to Routine Diagnostics - a Retrospective Analysis of AMLCG Study Patients

Tyrosin Kinase Inhibition Restores the Membrane Localization of FLT3-ITD

Functional Diversity of Single Stem Cell Clones in Patients' Acute Lymphoblastic Leukemia Growing in Mice: An Adverse Subclone with Distinct DNA-Methylation Pattern, Slow Growth In Vivo and Drug Resistance

Molecular Alterations in Refractory Acute Myeloid Leukemia and Persistent Preleukemic Lesions Are Disclosed Using Mesenchymal Stromal Cells As Germline Control

DNMT3A Mutations Associate with Shorter Survival and Modulate the Prognostic Impact of Mutated NPM1: an Analysis Based on Comprehensive Mutational Screening of 660 AML Patients Treated on German AML Cooperative Group (AMLCG) Trials

Detection of Chromosomal Aberrations in Acute Myeloid Leukemia By Copy Number Alteration Analysis of Exome Sequencing Data

Mutations of Genes Linked to Epigenetic Regulation Are Frequently Gained in Relapsed Cytogenetically Normal Acute Myeloid Leukemia

Targeted, Deep Sequencing of Adult AML Patients Treated on the AMLCG-2008 Trial Detects Clonal Heterogeneity in 52% of Patients at Initial Diagnosis and Reveals Patterns of Clonal Evolution

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American Society of Hematology

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ASH Publications

American Society of Hematology

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