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Philipp Sergeev
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Journal Articles

The Impact of the Peptide Drug Conjugate Melflufen on the Myeloma Tumour Microenvironment

Philipp Sergeev, Juho Jalmari Miettinen, Stefan Svensson Gelius, Klara Acs, Caroline A. Heckman
Journal: Blood
Blood (2023) 142 (Supplement 1): 5781.
https://doi.org/10.1182/blood-2023-188603
Published: 2023
Journal Articles

Label-Free High Dimensional Single Cell Morphological Profiling of Different Hematological Malignancies By Ghost Cytometry

Asako Tsubouchi, Juho Jalmari Miettinen, Keisuke Wagatsuma, Satoru Akai, Yuri An, Mika Uematsu, Philipp Sergeev, Dimitrios Tsallos, Markus Vaha-Koskela, Sadao Ota, Caroline A. Heckman
Journal: Blood
Blood (2023) 142 (Supplement 1): 5347.
https://doi.org/10.1182/blood-2023-188393
Published: 2023
Journal Articles

Combined Single Cell Flow Cytometry and Imaging Analyses Reveal Immunomodulatory Effects Exerted By Targeted Phospho-SYK Inhibitors with Elevated Sensitivity in NPM1 Mutated AML

Bridget A Robinson, Philipp Sergeev, Yoko Kosaka, Thomas Jacob, Andy Kaempf, Evan F. Lind, Cristina Tognon, Luis A. Carvajal, Jorge F. DiMartino, Caroline A. Heckman, Tania Q Vu
Journal: Blood
Blood (2023) 142 (Supplement 1): 5037.
https://doi.org/10.1182/blood-2023-186506
Published: 2023
Journal Articles

A Potential Role of NK Cells and ABCB9 in Modulating the Response to Melflufen in Multiple Myeloma

Philipp Sergeev, Sadiksha Adhikari, Juho J. Miettinen, Maiju-Emilia Huppunen, Minna Suvela, Ana Slipicevic, Nina N. Nupponen, Klara Acs, Fredrik Lehmann, Caroline A. Heckman
Journal: Blood
Blood (2022) 140 (Supplement 1): 6000–6001.
https://doi.org/10.1182/blood-2022-162182
Published: 2022
Journal Articles

Deep Immune Profiling in Multiple Myeloma at Diagnosis and Under Lenalidomide Maintenance Therapy

Raija Helena Silvennoinen, Komal Kumar Javarappa, Sini Luoma, Philipp Sergeev, Tiina J Öhman, Markku Varjosalo, Pekka Anttila, Marjaana Säily, Anu Partanen, Marja Sankelo, Caroline A. Heckman
Journal: Blood
Blood (2021) 138 (Supplement 1): 1597.
https://doi.org/10.1182/blood-2021-149090
Published: 2021
Journal Articles

Preclinical Activity of Selective SYK Inhibitors, Entospletinib and Lanraplenib, Alone or Combined with Targeted Agents in Ex Vivo AML Models with Diverse Mutational Backgrounds

Melinda A. L. Day, Philipp Sergeev, Caroline A. Heckman, Anna Schinzel, Nikolaus D. Obholzer, Charles Y. Lin, Pavan Kumar, Jorge DiMartino, Douglas C. Saffran
Journal: Blood
Blood (2021) 138 (Supplement 1): 3356.
https://doi.org/10.1182/blood-2021-146180
Published: 2021
Journal Articles

Single Cell RNA Sequencing Identifies Potential Molecular Indicators of Response to Melflufen in Multiple Myeloma

Philipp Sergeev, Sadiksha Adhikari, Juho J. Miettinen, Maiju-Emilia Huppunen, Minna Suvela, Ana Slipicevic, Nina N. Nupponen, Fredrik Lehmann, Caroline A. Heckman
Journal: Blood
Blood (2021) 138 (Supplement 1): 1194.
https://doi.org/10.1182/blood-2021-147191
Published: 2021