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PierAngelo Spedini
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Journal Articles

Progressive Down Regulation of JAK-STAT, Cell Cycle, and ABC Transporter Genes in CD34+/Lin- Cells of Chronic-Phase Chronic Myeloid Leukemia (CP-CML) Patients at Diagnosis Vs. 12 Months of Nilotinib Treatment Vs. Healthy Subjects

Alessandra Trojani, Ester Pungolino, Giuseppe Rossi, Mariella D'adda, Luca Emanuele Bossi, Giacomo Baruzzo, Barbara Di Camillo, Alessandra Perego, Mauro Turrini, Chiara Elena, MD, Lorenza Maria Borin, Alessandra Iurlo, MD PhD, Simona Malato, Francesco Spina, Maria Luisa Latargia, Pierangelo Spedini, Salvatore Artale, Michela Anghilieri, Maria Cristina Carraro, Cristina Bucelli, Gabriella De Canal, Enrica Morra, Roberto Cairoli, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 5034.
https://doi.org/10.1182/blood-2019-125595
Published: 2019
Journal Articles

Nilotinib Deregulates Cell Cycle Checkpoints, ABC Transporters Genes and JAK-STAT Signaling Pathway of CD34+/Lin- Cells in Chronic-Phase Chronic Myeloid Leukemia (CP-CML) Patients after 12 Months of Treatment

Alessandra Trojani, PhD, Ester Pungolino, Giuseppe Rossi, MD, Mariella D'adda, MD, Milena Lodola, PhD, Alessandra Dal Molin, PhD, Giacomo Baruzzo, PhD, Alessandra Perego, MD, Mauro Turrini, MD, Chiara Elena, MD, Lorenza Maria Borin, MDcal doctor, Alessandra Iurlo, Simona Malato, MD, Francesco Spina, MD, Maria Luisa Latargia, MD, Pierangelo Spedini, MD, Salvatore Artale, MD, Michela Anghilieri, MD, Carraro Maria Cristina, MD, Cristina Bucelli, MD, Gabriella De Canal, PhD, Enrica Morra, MD, Roberto Cairoli
Journal: Blood
Blood (2018) 132 (Supplement 1): 5122.
https://doi.org/10.1182/blood-2018-99-112188
Published: 2018
Journal Articles

Combining Imatinib-Following-Nilotinib Treatment in First Line Therapy for Chronic Phase Chronic Myeloid Leukemia. Update from the PhilosoPhi34 Study at 24 Months of Follow-up

Maria Luisa Pioltelli, MD, Ester Pungolino, Mariella D'adda, MD, Chiara Elena, MD, Lorenza Maria Borin, MDcal doctor, Alessandra Perego, MD, Alessandra Iurlo, Alessandra Trojani, PhD, Mauro Turrini, MD, Marianna Caramella, MD, Pierangelo Spedini, MD, Simona Malato, MD, Francesco Spina, MD, Salvatore Artale, MD, Mariacristina Carraro, Nicola Orofino, MD, Michela Anghilieri, MD, Mirko Farina, MD, Maria Luisa Latargia, MD, Giuseppe Rossi, MD, Enrica Morra, MD, Roberto Cairoli
Journal: Blood
Blood (2018) 132 (Supplement 1): 5435.
https://doi.org/10.1182/blood-2018-99-113496
Published: 2018
Journal Articles

Jak-2 and Nfkbia G ene Expression Play a Strategic Role in Chronic Myeloid Leukemia (CML) Molecular Response during Early Nilotinib Treatment: The PhilosoPhi34 Data

Ester Pungolino, Mariella D'adda, MD, Alessandra Trojani, PhD, Alessandra Perego, MD, Chiara Elena, MD, Alessandra Iurlo, Simona Malato, MD, Mauro Turrini, MD, Gabriella De Canal, PhD, Lorenza Borin, MD, Milena Lodola, PhD, Marianna Caramella, MD, Salvatore Artale, MD, Francesco Spina, MD, Maria Luisa Latargia, MD, Michela Anghilieri, MD, Pierangelo Spedini, MD, Mariacristina Carraro, Barbara Di Camillo, Doriana Gramegna, MD, Maria Luisa Pioltelli, MD, Giuseppe Rossi, MD, Enrica Morra, MD, Roberto Cairoli
Journal: Blood
Blood (2018) 132 (Supplement 1): 5118.
https://doi.org/10.1182/blood-2018-99-113273
Published: 2018
Journal Articles

Refining Hellström-Lindberg Score: Which Patients Could Benefit from Standard Dose EPO?

Marta Riva, MD, Gianluigi Reda, MD, Emanuele Ravano, MD, Ramona Cassin, MD, Mariarita Sciumè, MD, Pierangelo Spedini, MD, Giambattista Bertani, MD, Michele Nichelatti, PhD, Agostino Cortelezzi, Prof, Roberto Cairoli, MD, Alfredo Molteni, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 2981.
https://doi.org/10.1182/blood.V130.Suppl_1.2981.2981
Published: 2017
Journal Articles

Preliminary Experience of Imatinib after Nilotinib in the First Line Treatment of Chronic Myeloid Leukemia

Ester Pungolino, Mariella D'adda, Alessandra Perego, MD, Ester Maria Orlandi, MD, Mauro Turrini, MD, Lorenza Maria Borin, MD, Alessandra Iurlo, MD PhD, Salvatore Artale, Maria Luisa Latargia, MD, Michela Anghilieri, MD, Simona Malato, MD, Alessandra Trojani, Francesco Spina, MD, Carraro Maria Cristina, MD, Maria Luisa Pioltelli, MD, Chiara Elena, Cristina Bucelli, MD, Pierangelo Spedini, MD, Giuseppe Rossi, MD, Enrica Morra, MD, Roberto Cairoli, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 2889.
https://doi.org/10.1182/blood.V130.Suppl_1.2889.2889
Published: 2017
Journal Articles

Thrombosis History and Relationship With Low Thrombocytosis, Leukocytosis, and Other Characteristics At Diagnosis In 977 Essential Thrombocythemia Patients A Multivariate Analysis Of The Registro Italiano Trombocitemie (RIT)

Luigi Gugliotta, MD, Alessandra Iurlo, MD, Alessia Tieghi, MD, Gabriele Gugliotta, MD, Anna Candoni, MD, Elisa Rumi, MD, Elisabetta Antonioli, MD, Alessandra Ricco, Monica Lunghi, MD, Rosario Potito Scalzulli, MD, Anna Rita Scortechini, MD, Katia Codeluppi, Bruno Martino, MD, Alfredo Dragani, MD, Andrea Patriarca, MD, Vincenzo Martinelli, MD, Giorgia Battipaglia, MD, Maria Luigia Randi, MD, Elisabetta Cosi, MD, Anna Marina Liberati, MD, Viviana Appolloni, MD, Nilla Maschio, MD, Lucia Mastrullo, MD, Maria Rosaria Villa, MD, Maria Rosaria Esposito, MD, Nicola Cantore, MD, Fausto Palmieri, MD, Maria Langella, MD, Flavia Rivellini, MD, Maria Gabriella Mazzucconi, MD, Cristina Santoro, MD, Ercole De Biasi, MD, Angela Rago, MD, Nicola Polverelli, MD, Pierangelo Spedini, MD, Emma Cacciola, MD, Rossella R Cacciola, MD, Ivana Pierri, MD, Laura Mitsheunig, MD, Marzia Salvucci, Ferdinando Porretto, MD, Andrea Piccin, MD, Umberto Santoro, Gianluca Gaidano, Giuseppe Cimino, MD, Francesco Lanza, MD, Agostino Cortelezzi, MD, Giuseppe Tagariello, MD, Serena Rupoli, MD, Giorgina Specchia, Francesco Passamonti, MD, Alessandro M. Vannucchi, MD, Fabrizio Pane, Nicola Vianelli, MD, Rossella Miglio, Paola Monari
Journal: Blood
Blood (2013) 122 (21): 2829.
https://doi.org/10.1182/blood.V122.21.2829.2829
Published: 2013
Journal Articles

An open-label, pilot study of fludarabine, cyclophosphamide, and alemtuzumab in relapsed/refractory patients with B-cell chronic lymphocytic leukemia

Clinical Trials & Observations
Marco Montillo, Alessandra Tedeschi, Valeria Belsito Petrizzi, Francesca Ricci, Monica Crugnola, Mauro Spriano, Pierangelo Spedini, Fiorella Ilariucci, Lilj Uziel, Immacolata Attolico, Eleonora Vismara, Angelo De Blasio, Alfonso Zaccaria, Enrica Morra
Journal: Blood
Blood (2011) 118 (15): 4079–4085.
https://doi.org/10.1182/blood-2011-05-351833
Published: 2011
Journal Articles

Fludarabine, Cyclophosphamide, and Alemtuzumab (FCC) In Relapsed/Refractory Patients with B-Cell Chronic Lymphocytic Leukemia (CLL): Final Report of the Italian Study

Marco Montillo, MD, Alessandra Tedeschi, Francesca Ricci, Alfonso Zaccaria, Monica Crugnola, Mauro Spriano, PierAngelo Spedini, Fiorella Ilariucci, Lilj Uziel, Immacolata Attolico, Angelo De Blasio, Eleonora Vismara, Enrica Morra, Valeria Belsito Petrizzi
Journal: Blood
Blood (2010) 116 (21): 1384.
https://doi.org/10.1182/blood.V116.21.1384.1384
Published: 2010
Journal Articles

Azacitidine Low-Dose Schedule In Low-Risk Myelodysplastic Syndromes. Preliminary Results of a Multicenter Phase II Study

Carla Filì, MD, Carlo Finelli, MD, Marco Gobbi, MD, Giovanni Martinelli, MD, Ilaria Iacobucci, MD, Emanuela Ottaviani, MD, Lucio Cocco, MD, Matilde Follo, MD, Anna Candoni, Erika Simeone, Maurizio Miglino, MD, Francesco Lauria, MD, Monica Bocchia, MD, Marzia Defina, MD, Cristina Clissa, MD, Francesco Lanza, Antonio Curti, MD, Stefania Paolini, MD, PierAngelo Spedini, Cristina Skert, MD, Cesare Bergonzi, MD, Michele Malagola, MD, Annalisa Peli, MD, Alessandro Turra, MD, Federica Cattina, MD, Chiara Colombi, Domenico Russo, MD
Journal: Blood
Blood (2010) 116 (21): 4029.
https://doi.org/10.1182/blood.V116.21.4029.4029
Published: 2010
Journal Articles

A Recent Update of Three Consecutive Prospective Trials with High-Dose Therapy and Autograft, without or with Rituximab, as Primary Treatment for Advanced-Stage Follicular Lymphoma (FL) Shows a Sizeable Group of Patients Surviving in Continuous Complete Remission up to 16 Years After the End of Treatment: Should We Still Consider FL An Incurable Disease ?.

Corrado Tarella, Marco Ladetto, Fabio Benedetti, Umberto Vitolo, Alessandro Pulsoni, Caterina Patti, Vincenzo Callea, Alessandro Rambaldi, Andrea Piccin, Michele Magni, Maurizio Musso, Emilio Iannitto, Pierangelo Spedini, Anna Marina Liberati, Fabio Ciceri, Andrea Gallamini, Francesco Rodeghiero, Guido Gini, Alberto De Crescenzo, Francesco Di Raimondo, Alessandro Levis, Teodoro Chisesi, Tommasina Perrone, Delia Rota Scalabrini, Giuseppe Rossi, Angelo Michele Carella, Guido Parvis, Ignazio Majolino, Roberto Passera, Marco Ruella, Alessandro Pileri, Alessandro Gianni, Paolo Corradini
Journal: Blood
Blood (2009) 114 (22): 882.
https://doi.org/10.1182/blood.V114.22.882.882
Published: 2009
Journal Articles

Combined Fludarabine, Cyclophosphamide, and Alemtuzumab (FCC), an Active Regimen for Treated Patients with Chronic Lymphocytic Leukemia (CLL).

Marco Montillo, MD, Sara Miqueleiz, MD, Alessandra Tedeschi, MD, Francesca Ricci, MD, Eleonora Vismara, MD, Denis Ciapanna, MD, Valeria Belsito Petrizzi, MD, Monica Crugnola, MD, Mauro Spriano, MD, Lilj Uziel, MD, Angelo De Blasio, MD, Pierangelo Spedini, PhD, Enrica Morra, MD
Journal: Blood
Blood (2007) 110 (11): 3133.
https://doi.org/10.1182/blood.V110.11.3133.3133
Published: 2007