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Journal Articles

Andexanet Alfa Reverses Anticoagulation Effects of Enoxaparin and Associated Bleeding in a Rabbit Acute Hemorrhage Model

Polly Pine, PhD, Genmin Lu, PhD, Deogracias Canivel, Pratikhya Pratikhya, BS, MSc, Francis DeGuzman, PhD, Mark Karbarz, PhD, Kentaro Takeda, BS, John Malinowski, PhD, Janet M. Leeds, PhD, John T. Curnutte, MD PhD, Pamela B. Conley, PhD
Journal: Blood
Blood (2016) 128 (22): 1445.
https://doi.org/10.1182/blood.V128.22.1445.1445
Published: 2016
Journal Articles

R723, a selective JAK2 inhibitor, effectively treats JAK2V617F-induced murine myeloproliferative neoplasm

Kotaro Shide, Takuro Kameda, Vadim Markovtsov, Haruko K. Shimoda, Elizabeth Tonkin, Shuling Fang, Chian Liu, Marina Gelman, Wayne Lang, Jason Romero, John McLaughlin, Somasekhar Bhamidipati, Jeffrey Clough, Caroline Low, Andrea Reitsma, Stacey Siu, Polly Pine, Gary Park, Allan Torneros, Matt Duan, Rajinder Singh, Donald G. Payan, Takuya Matsunaga, Yasumichi Hitoshi, Kazuya Shimoda
Journal: Blood
Blood (2011) 117 (25): 6866–6875.
https://doi.org/10.1182/blood-2010-01-262535
Published: 2011
Includes: Supplemental data
Journal Articles

Rational Combinations Including a Novel Syk Inhibitor, Fostamatinib Disodium (FosD) in Diffuse Large B Cell Lymphoma.

Randall M Rossi, Valerie Grose, Polly Pine, Richard I Fisher, MD, Craig T. Jordan, PhD, Jonathan W. Friedberg, MD
Journal: Blood
Blood (2009) 114 (22): 283.
https://doi.org/10.1182/blood.V114.22.283.283
Published: 2009
Journal Articles

Role of Spleen Tyrosine Kinase Signaling in Early B Cell Acute Lymphoblastic Leukemia.

Tatiana Perova, MSc, Lauryl Nutter, PhD, Irina Matei, PhD, Ildiko Grandal, MSc, Polly Pine, Yasumichi Hitoshi, PhD, Johann K. Hitzler, MD, Cynthia J Guidos, PhD, Jayne S Danska, PhD
Journal: Blood
Blood (2009) 114 (22): 3092.
https://doi.org/10.1182/blood.V114.22.3092.3092
Published: 2009
Journal Articles

Mouse models of non-Hodgkin lymphoma reveal Syk as an important therapeutic target

Ryan M. Young, Ian R. Hardy, Raedun L. Clarke, Nicolai Lundy, Polly Pine, Brian C. Turner, Terry A. Potter, Yosef Refaeli
Journal: Blood
Blood (2009) 113 (11): 2508–2516.
https://doi.org/10.1182/blood-2008-05-158618
Published: 2009
Includes: Supplemental data
Journal Articles

In Vitro and in Vivo Inhibition of JAK2 Signaling by Potent and Selective JAK2 Inhibitor

Vadim Markovtsov, Elizabeth Tonkin, Shuling Fang, Chiang Liu, Marina Gelman, Wayne Lang, Jason Romero, John McLaughlin, Somasekhar Bhamidipati, Jeffrey Clough, Rajinder Singh, Caroline Low, Andrea Reitsma, Vanessa Taylor, Stacey Siu, Gary Park, David Sweeney, Polly Pine, Allan Torneros, George Clemens, Matt Duan, Ruby Daniel, Donald Payan, MD, Sacha Holland, Yasumichi Hitoshi, Ph.D.
Journal: Blood
Blood (2008) 112 (11): 3721.
https://doi.org/10.1182/blood.V112.11.3721.3721
Published: 2008
Journal Articles

Targeting Myeloproliferative Diseases with JAK2 Inhibitors.

Vadim Markovtsov, PhD, Diane Yu, Marina Gelman, PhD, Wayne Lang, Vanessa C. Taylor, PhD, Stacey Huynh, Roy Frances, Shuling Fang, John McLaughlin, Sohasekhar Bhamidipati, PhD, Jeffrey Clough, PhD, Rajinder Singh, PhD, Gary Park, PhD, David Sweeney, PhD, Elizabeth Tonkin, PhD, Rena Bahjat, PhD, Betty Chang, PhD, Polly Pine, PhD, Ruby Daniel, PhD, Donald G. Payan, PhD, Sacha Holland, PhD, Yasumichi Hitoshi, PhD
Journal: Blood
Blood (2007) 110 (11): 3550.
https://doi.org/10.1182/blood.V110.11.3550.3550
Published: 2007
Journal Articles

Inhibition of Immune Thrombocytopenic Purpura (ITP) by an Orally Bioavailable Inhibitor of Syk Kinase Activity.

Andrew R. Crow, BSc, Vinayakumar Siragam, PhD, John Freedman, MD, Elliott B. Grossbard, MD, Esteban S. Masuda, PhD, Polly Pine, PhD, Alan H. Lazarus, PhD
Journal: Blood
Blood (2005) 106 (11): 2165.
https://doi.org/10.1182/blood.V106.11.2165.2165
Published: 2005