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Journal Articles

Blockade of PD-L1/CD80 Interactions Augments Function of Activated Donor T Cells Results in Augmenting Gvhd Induced By Donor Naïve CD8 + t Cells and GVL Effect Mediated By Donor Memory CD8 + T Cells

Qingxiao Song, Yuankun Zhang, Kaniel Cassady, Qinjian Li, Paul J. Martin, Defu Zeng

Blood (2023) 142 (Supplement 1): 4793.

https://doi.org/10.1182/blood-2023-190733

Published: 2023

Journal Articles

Targeting Intestinal Epithelial Ceacam1 Expands Peripheral Tregs and Prevents Steroid-Refractory Acute Gut Graft-Versus-Host Disease

Qingxiao Song, Moqian Zheng, Qinjian Li, Xiwei Wu, Hanjun Qin, Tae Hyuk Kang, Yaqun Hong, Bixin Wang, Maciej Kujawski, Jack Shively, Ryotaro Nakamura, Paul J Martin, Defu Zeng

Blood (2022) 140 (Supplement 1): 10225–10226.

https://doi.org/10.1182/blood-2022-163572

Published: 2022

Journal Articles

Tolerogenic anti–IL-2 mAb prevents graft-versus-host disease while preserving strong graft-versus-leukemia activity

Qingxiao Song, Xiaoning Wang, Xiwei Wu, Hanjun Qin, Yingfei Li, Arthur D. Riggs, Paul J. Martin, Yuan-Zhong Chen, Defu Zeng

Blood (2021) 137 (16): 2243–2255.

https://doi.org/10.1182/blood.2020006345

Published: 2021

Includes: Supplemental data

Journal Articles

Expansion of Th/Tc17 T Cells and Loss of CX3CR1 + Macrophages Play a Critical Role in the Pathogenesis of Steroid-Refractory Acute Intestinal Gvhd

Qingxiao Song, MD PhD, Xiaoning Wang, MD, Paul J Martin, MD, Yuanzhong Chen, MD PhD, Defu Zeng, MD PhD

Blood (2019) 134 (Supplement_1): 1925.

https://doi.org/10.1182/blood-2019-126261

Published: 2019

Journal Articles

Stat3 -/- Alloreactive Donor T Cells Reduce FAO but Increase Leakage of ROS in Response to PD-1 Signaling Triggered By Host-Tissue PD-L1, Leading to Prevention of Gvhd While Preserving GVL Effect

Xiaoqi Wang, MD, Shijie Yang, PhD, Yating Wang, PhD, Xiwei Wu, PhD, Martha Salas, Qingxiao Song, MD PhD, Hanjun Qin, Ubaydah Nasri, Arthur D. Riggs, PhD, Paul J Martin, MD, Xi Zhang, Defu Zeng, MD PhD

Blood (2019) 134 (Supplement_1): 198.

https://doi.org/10.1182/blood-2019-127228

Published: 2019

Journal Articles

Combination Therapy of Allogeneic HSCT and In Vivo Activated iNKT Cells Prevents Acute Gvhd While Augmenting GVL Effect

Samuel Zeng, Qingxiao Song, MD PhD, Shanshan Tang, Xi Wang, PhD, Yuchen Wang, PhD, Defu Zeng, MD PhD, Lili Yang, PhD

Blood (2019) 134 (Supplement_1): 4439.

https://doi.org/10.1182/blood-2019-130826

Published: 2019

Journal Articles

Tissue-Resident PSGL1 lo CD4 + T Cells Interact with B Cells Via PD-1 and PD-L2 in Gvhd Target Tissues to Augment Autoimmune-like Chronic Gvhd

Xiaohui Kong, PhD, Deye Zeng, MD, Xiwei Wu, PhD, Shijie Yang, PhD, Bixin Wang, Qingxiao Song, MD PhD, Yongping Zhu, Martha Salas, Hanjun Qin, Ubaydah Nasri, Ryotaro Nakamura, MD, Paul J Martin, MD, Aimin Huang, Defu Zeng, MD PhD

Blood (2019) 134 (Supplement_1): 5607.

https://doi.org/10.1182/blood-2019-126315

Published: 2019

Journal Articles

Neutralizing IL-2 Early after HCT Specifically Prevents Expansion of Donor GM-CSF-Producing CD4 + T Cells That Initiate Acute Gut Gvhd

Qingxiao Song, MD, Xiaoning Wang, MD, Paul J Martin, MD, Yuanzhong Chen, MD PhD, Defu Zeng, MD

Blood (2018) 132 (Supplement 1): 2030.

https://doi.org/10.1182/blood-2018-99-119966

Published: 2018

Journal Articles

Stat3 Regulates Alloreactive T Cell Susceptibility Towards PD-L1-Mediated Tolerance Signaling, Gvhd and GVL Activity

Shijie Yang, PhD, Xiaoqi Wang, MD, Yuankun Zhang, PhD, Deye Zeng, MD, Qingxiao Song, MD, Paul J Martin, MD, Xi Zhang, Defu Zeng, MD

Blood (2018) 132 (Supplement 1): 3323.

https://doi.org/10.1182/blood-2018-99-119474

Published: 2018

Journal Articles

Antibodies from donor B cells perpetuate cutaneous chronic graft-versus-host disease in mice

Hua Jin, Xiong Ni, Ruishu Deng, Qingxiao Song, James Young, Kaniel Cassady, Mingfeng Zhang, Stephen Forman, Paul J. Martin, Qifa Liu, Defu Zeng

Blood (2016) 127 (18): 2249–2260.

https://doi.org/10.1182/blood-2015-09-668145

Published: 2016

Includes: Supplemental data

Journal Articles

Host Tissue PD-L1 Separates GVL Effect from Gvhd after Temporary Depletion of Donor CD4 + T Cells Early after HCT

Xiong Ni, MD, Qingxiao Song, MD, Ruishu Deng, MD PhD, Hua Jin, BS, Kaniel M. Cassady, BS, Mingfeng Zhang, PhD, Stephen J. Forman, MD, Paul J. Martin, MD, Jianmin Wang, MD PhD, Defu Zeng, MD

Blood (2015) 126 (23): 1882.

https://doi.org/10.1182/blood.V126.23.1882.1882

Published: 2015

NARROW

Blockade of PD-L1/CD80 Interactions Augments Function of Activated Donor T Cells Results in Augmenting Gvhd Induced By Donor Naïve CD8 + t Cells and GVL Effect Mediated By Donor Memory CD8 + T Cells

Targeting Intestinal Epithelial Ceacam1 Expands Peripheral Tregs and Prevents Steroid-Refractory Acute Gut Graft-Versus-Host Disease

Tolerogenic anti–IL-2 mAb prevents graft-versus-host disease while preserving strong graft-versus-leukemia activity

Expansion of Th/Tc17 T Cells and Loss of CX3CR1 + Macrophages Play a Critical Role in the Pathogenesis of Steroid-Refractory Acute Intestinal Gvhd

Stat3 -/- Alloreactive Donor T Cells Reduce FAO but Increase Leakage of ROS in Response to PD-1 Signaling Triggered By Host-Tissue PD-L1, Leading to Prevention of Gvhd While Preserving GVL Effect

Combination Therapy of Allogeneic HSCT and In Vivo Activated iNKT Cells Prevents Acute Gvhd While Augmenting GVL Effect

Tissue-Resident PSGL1 lo CD4 + T Cells Interact with B Cells Via PD-1 and PD-L2 in Gvhd Target Tissues to Augment Autoimmune-like Chronic Gvhd

Neutralizing IL-2 Early after HCT Specifically Prevents Expansion of Donor GM-CSF-Producing CD4 + T Cells That Initiate Acute Gut Gvhd

Stat3 Regulates Alloreactive T Cell Susceptibility Towards PD-L1-Mediated Tolerance Signaling, Gvhd and GVL Activity

Antibodies from donor B cells perpetuate cutaneous chronic graft-versus-host disease in mice

Host Tissue PD-L1 Separates GVL Effect from Gvhd after Temporary Depletion of Donor CD4 + T Cells Early after HCT

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American Society of Hematology

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ASH Publications

American Society of Hematology

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