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Raffaella Toso
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Journal Articles

Adeno-Associated Viral Vector Delivery of Optimized Human Factor VIII Achieves Therapeutic Factor VIII Levels in Non-Human Primates

Xavier M. Anguela, PhD, Liron Elkouby, PhD, Raffaella Toso, PhD, Marti DiPietro, MS, Robert J. Davidson, Katherine A. High, MD, Denise E. Sabatino, PhD
Journal: Blood
Blood (2015) 126 (23): 199.
https://doi.org/10.1182/blood.V126.23.199.199
Published: 2015
Journal Articles

Coagulation factor V mediates inhibition of tissue factor signaling by activated protein C in mice

Hai Po H. Liang, Edward J. Kerschen, Sreemanti Basu, Irene Hernandez, Mark Zogg, Shuang Jia, Martin J. Hessner, Raffaella Toso, Alireza R. Rezaie, José A. Fernández, Rodney M. Camire, Wolfram Ruf, John H. Griffin, Hartmut Weiler
Journal: Blood
Blood (2015) 126 (21): 2415–2423.
https://doi.org/10.1182/blood-2015-05-644401
Published: 2015
Includes: Supplemental data
Journal Articles

The C-Terminus Basic Region of TFPIα Dynamically Regulates FV(a) Function: Evaluation of FV-Short

Raffaella Toso, PhD, Matthew W Bunce, PhD, Rodney M. Camire, PhD
Journal: Blood
Blood (2014) 124 (21): 578.
https://doi.org/10.1182/blood.V124.21.578.578
Published: 2014
Journal Articles

Factor V Inhibits PAR2-Mediated Lethal Inflammation

Edward J Kerschen, PhD, Hai-Po Helena Liang, Jose A. Fernandez, MD, PhD, Raffaella Toso, PhD, Wolfram Ruf, MD, Rodney M. Camire, PhD, John H. Griffin, PhD, Hartmut Weiler, PhD
Journal: Blood
Blood (2012) 120 (21): 3360.
https://doi.org/10.1182/blood.V120.21.3360.3360
Published: 2012
Journal Articles

Mapping the Location of Autoinhibitory B-Domain Motifs within Factor V: New Insights Into How Factor V Activation Unfolds

Raffaella Toso, PhD, Matthew W. Bunce, PhD, Rodney M. Camire, PhD
Journal: Blood
Blood (2012) 120 (21): 495.
https://doi.org/10.1182/blood.V120.21.495.495
Published: 2012
Journal Articles

Zymogen-like factor Xa variants restore thrombin generation and effectively bypass the intrinsic pathway in vitro

Matthew W. Bunce, Raffaella Toso, Rodney M. Camire
Journal: Blood
Blood (2011) 117 (1): 290–298.
https://doi.org/10.1182/blood-2010-08-300756
Published: 2011
Journal Articles

The Development of Novel Hemostatic Bypassing Molecules.

Rodney M. Camire, PhD, Matthew Bunce, PhD, Lacramioara Ivanciu, PhD, Raffaella Toso, PhD, Harre D. Downey, Jian-Hua Liu, Valder R. Arruda, MD, PhD
Journal: Blood
Blood (2009) 114 (22): SCI-20.
https://doi.org/10.1182/blood.V114.22.SCI-20.SCI-20
Published: 2009
Journal Articles

Recombinant canine B-domain–deleted FVIII exhibits high specific activity and is safe in the canine hemophilia A model

Brief Report
Denise E. Sabatino, Christian Furlan Freguia, Raffaella Toso, Andrey Santos, Elizabeth P. Merricks, Haig H. Kazazian, Jr, Timothy C. Nichols, Rodney M. Camire, Valder R. Arruda
Journal: Blood
Blood (2009) 114 (20): 4562–4565.
https://doi.org/10.1182/blood-2009-05-220327
Published: 2009
Includes: Supplemental data
Journal Articles

Zymogen-Like Factor Xa Variants Restore Thrombin Generation and Effectively Bypass the Intrinsic Pathway in Vitro

Matthew W Bunce, Ph.D., Raffaella Toso, Ph.D., Valder R. Arruda, M.D., Ph.D., Rodney M. Camire, Ph.D.
Journal: Blood
Blood (2008) 112 (11): 240.
https://doi.org/10.1182/blood.V112.11.240.240
Published: 2008
Journal Articles

Factor Xa Variants as Novel Bypass Agents for the Treatment of Hemophilia in Murine Models

Lacramioara Ivanciu, Ph.D., Raffaella Toso, Ph.D., Alexander Schlachterman, M.D., Harre Downey, B.S., Jian-Hua Liu, B.S., Valder R. Arruda, M.D., Ph.D., Rodney M. Camire, Ph.D.
Journal: Blood
Blood (2008) 112 (11): 239.
https://doi.org/10.1182/blood.V112.11.239.239
Published: 2008
Journal Articles

Successful Production of Canine FVIII: Biochemical and Functional Characterization in Hemophilia A Dogs.

Christian Furlan Freguia, PhD, Denise E. Sabatino, PhD, Andrey Santos, BS, Amy Lange, BS, Raffaella Toso, PhD, Timothy C. Nichols, MD, Rodney M. Camire, PhD, Valder R. Arruda, MD, PhD
Journal: Blood
Blood (2007) 110 (11): 495.
https://doi.org/10.1182/blood.V110.11.495.495
Published: 2007
Journal Articles

Destabilization of the Factor V B-Domain Results in Procofactor Activation.

Rodney M. Camire, PhD, Hua Zhu, B.A., Mettine H.A. Bos, Ph.D., Raffaella Toso, Ph.D.
Journal: Blood
Blood (2006) 108 (11): 198.
https://doi.org/10.1182/blood.V108.11.198.198
Published: 2006
Journal Articles

Alteration of the Factor X Zymogen to Protease Transition Provides Evidence for Allosteric Linkage between the S1 and FVa Binding Sites.

Raffaella Toso, PhD, Hua Zhu, BS, Rodney M. Camire, PhD
Journal: Blood
Blood (2005) 106 (11): 30.
https://doi.org/10.1182/blood.V106.11.30.30
Published: 2005
Journal Articles

The Contribution of Hirudin-Like Acidic Sequences within the Factor Va Heavy Chain to Prothrombinase Function.

Raffaella Toso, PhD, Hua Zhu, BS, Rodney M. Camire, PhD
Journal: Blood
Blood (2004) 104 (11): 1714.
https://doi.org/10.1182/blood.V104.11.1714.1714
Published: 2004
Journal Articles

Modulation of factor VII levels by intron 7 polymorphisms: population and in vitro studies

Mirko Pinotti, Raffaella Toso, Domenico Girelli, Debora Bindini, Paolo Ferraresi, Maria L. Papa, Roberto Corrocher, Giovanna Marchetti, Francesco Bernardi
Journal: Blood
Blood (2000) 95 (11): 3423–3428.
https://doi.org/10.1182/blood.V95.11.3423
Published: 2000