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Journal Articles

Long-Term Real-World Experience of CPX-351 in Combined French-Italian Cohorts Identified High Rate of Negative Measurable Residual Disease (MRD) and Prolonged Overall Survival

Thomas Cluzeau, Fabio Guolo, Edmond Chiche, Paola Minetto, Ramy Rahmé, Sarah Bertoli, Livio Pagano, Jean-Baptiste Micol, Michele Gottardi, Pierre Peterlin, Sara Galimberti, Xavier Thomas, Giuliana Rizzuto, Mohamad Mohty, Michela Rondoni, Emmanuel Raffoux, Giambattista Bertani, Alexis Caulier, Michelina Dargenio, Caroline Bonmati, Atto Billio, Caroline Lejeune, Barbara Scappini, Arnaud Pigneux, Patrizia Zappasodi, Christian Recher, Norbert Vey, Francesco Grimaldi, Lionel Ades, Roberto Massimo Lemoli
Journal: Blood
Blood (2023) 142 (Supplement 1): 4255.
https://doi.org/10.1182/blood-2023-177951
Published: 2023
Journal Articles

Treatment of Adverse-Risk and Refractory/Relapsed Acute Myeloid Leukemia (AML) Patients with FLAG-IDA ± Venetoclax and CLAG-M: A Monocentric Experience

Ramy Rahmé, Valérie Vidal, Thomas Hueso, Lucie Le Meur, Marthe Rigal, Sarah Ivanoff, Sabine Brechignac, Regis Peffault De Latour, Claude Gardin, Thorsten Braun
Journal: Blood
Blood (2023) 142 (Supplement 1): 1520.
https://doi.org/10.1182/blood-2023-174356
Published: 2023
Journal Articles

Long Term Follow-up and Combined Phase 2 Results of Eprenetapopt (APR-246) and Azacitidine (AZA) in Patients with TP53 mutant Myelodysplastic Syndromes (MDS) and Oligoblastic Acute Myeloid Leukemia (AML)

David A. Sallman, Rami S. Komrokji, Amy E. DeZern, Marie Sebert, Guillermo Garcia-Manero, Ramy Rahmé, David P. Steensma, Jacqueline Lehmann che, Gail J. Roboz, Isabelle Madelaine, Mikkael A. Sekeres, Pierre Peterlin, Kendra Sweet, Odile Beyne Rauzy, Andrew T. Kuykendall, Christian Recher, Amy F McLemore, Aspasia Stamatoullas, Ling Zhang, Lise Willems, Qianxing Mo, Emmanuel Raffoux, Lisa Nardelli, Celine Berthon, Najla Al Ali, Bruno Quesnel, Eric Padron, Greg Korbel, Eyal C. Attar, Hagop Kantarjian, Alan F. List, Lionel Ades, Jeffrey E. Lancet, Pierre Fenaux, Thomas Cluzeau
Journal: Blood
Blood (2021) 138 (Supplement 1): 246.
https://doi.org/10.1182/blood-2021-153286
Published: 2021
Journal Articles

APR-246 Combined with Azacitidine (AZA) in TP53 Mutated Myelodysplastic Syndrome (MDS) and Acute Myeloid Leukemia (AML). a Phase 2 Study By the Groupe Francophone Des Myélodysplasies (GFM)

Thomas Cluzeau, MD PhD, Marie Sebert, MD, Ramy Rahmé, MD, Stefania Cuzzubbo, Anouk Walter-petrich, Jacqueline Lehmann che, Pierre Peterlin, Blandine Beve, Habiba Attalah, Fatiha Chermat, Elsa Miekoutima, Odile Beyne-Rauzy, Christian Recher, MD PhD, Aspasia Stamatoullas, MD, Lise Willems, MD, Emmanuel Raffoux, MD, Céline Berthon, MD PhD, Bruno Quesnel, Antoine Carpentier, David A Sallman, MD, Sylvie Chevret, MD PhD, Lionel Ades, MD PhD, Pierre Fenaux, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 677.
https://doi.org/10.1182/blood-2019-125579
Published: 2019
Journal Articles

CPX-351 Induces Deep Response and Suppress the Impact of Poor Prognosis Mutations ( TP53, ASXL1, RUNX1 and EVI1 ) Defined By ELN-2017 in t-AML and MRC AML: A Report from a Multicentric French Cohort

Edmond Chiche, Sarah Bertoli, MD PhD, Ramy Rahmé, MD, Jean Baptiste Micol, Florence Pasquier, MD PhD, Pierre Peterlin, Patrice Chevallier, MD, Xavier Thomas, MD PhD, Michael Loschi, MD PhD, Alexis Genthon, Olivier Legrand, MD PhD, Mohamad Mohty, MD PhD, Emmanuel Raffoux, MD, Patrick Auberger, PhD, Alexis Caulier, MD, Magalie Joris, MD, Caroline Bonmati, Gabrielle Roth Guepin, Mathieu Sauvezie, Caroline Lejeune, Arnaud Pigneux, Christian Recher, MD PhD, Lionel Ades, MD PhD, Thomas Cluzeau, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1355.
https://doi.org/10.1182/blood-2019-125623
Published: 2019
Journal Articles

Prognostic Impact of Clonal Diversity in Acute Myeloid Leukemia (AML) Treated with Intensive Chemotherapy (IC)

Marco Cerrano, MD, Marie Passet, PharmD, Loic Vasseur, MD, Pierre Hirsch, MD PhD, Xavier Thomas, MD PhD, Samuel Quentin, Justine Pasanisi, Florence Rabian, MD, Ramy Rahmé, MD, Etienne Lengline, MD, Emmanuel Raffoux, MD, Nathalie Dhedin, MD, Marie Sebert, MD, Odile Maarek, Anna Raimbault, PhD, Karine Celli-Lebras, CRA, Lionel Ades, MD PhD, Pierre Fenaux, MD PhD, Nicolas Boissel, MD PhD, Francois Delhommeau, MD PhD, Jean Soulier, MD PhD, Herve Dombret, MD PhD, Emmanuelle Clappier, PhD PharmD, Pierre Sujobert, MD PhD, Raphael Itzykson, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2700.
https://doi.org/10.1182/blood-2019-127475
Published: 2019
Journal Articles

Germline DDX41 mutations define a significant entity within adult MDS/AML patients

Brief Report
Marie Sébert, Marie Passet, Anna Raimbault, Ramy Rahmé, Emmanuel Raffoux, Flore Sicre de Fontbrune, Marco Cerrano, Samuel Quentin, Nadia Vasquez, Mélanie Da Costa, Nicolas Boissel, Hervé Dombret, Régis Peffault de Latour, Gérard Socié, Raphaël Itzykson, Pierre Fenaux, Jean Soulier, Lionel Adès, Emmanuelle Clappier
Journal: Blood
Blood (2019) 134 (17): 1441–1444.
https://doi.org/10.1182/blood.2019000909
Published: 2019
Includes: Supplemental data
Journal Articles

FLT3 -ITD impedes retinoic acid, but not arsenic, responses in murine acute promyelocytic leukemias

Cécile Esnault, Ramy Rahmé, Kim L. Rice, Caroline Berthier, Coline Gaillard, Samuel Quentin, Anne-Lise Maubert, Scott Kogan, Hugues de Thé
Journal: Blood
Blood (2019) 133 (13): 1495–1506.
https://doi.org/10.1182/blood-2018-07-866095
Published: 2019
Includes: Supplemental data
Journal Articles

Clinical and Molecular Characteristics of DDX41 -Mutated Patients in a Large Cohort of Sporadic MDS/AML

Marie Sebert, MD, Marie Passet, PharmD, Anna Raimbault, PhD, Samuel Quentin, Nadia Vasquez, Ramy Rahmé, Emmanuel Raffoux, Flore Sicre De Fontbrune, MD PhD, Regis Peffault De Latour, Raphael Itzykson, MD PhD, Pierre Fenaux, MD PhD, Jean Soulier, MDPhD, Lionel Ades, MD PhD, Emmanuelle Clappier, PhD PharmD
Journal: Blood
Blood (2018) 132 (Supplement 1): 797.
https://doi.org/10.1182/blood-2018-99-110668
Published: 2018
Journal Articles

Characteristics and Outcome of Older Patients with Acute Promyelocytic Leukemia Front-Line Treated with or without Arsenic Trioxide — an International Collaborative Study

Sabine Kayser, MD, Ramy Rahmé, David Martínez-Cuadron, MD, Gabriel Ghiaur, MD PhD, Xavier Thomas, MD, Marta Sobas, MD, Agnes Guerci Bresler, Salut Brunet, MD PhD, Arnaud Pigneux, MD PhD, Cristina Gil, MD, Emmanuel Raffoux, Mar Tormo, MD PhD, Norbert Vey, MD PhD, Javier de la Serna, MD, Olga Salamero, MD, Eva Lengfelder, MD, Mark J. Levis, MD, Pierre Fenaux, MD PhD, Miguel A. Sanz, MD, Richard F. Schlenk, MD, Uwe Platzbecker, Lionel Ades, MD PhD, Pau Montesinos, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 80.
https://doi.org/10.1182/blood-2018-99-111768
Published: 2018
Journal Articles

Intra-Tumor Heterogeneity in Acute Myeloid Leukemia (AML): Results from a Real Life Cohort

Marco Cerrano, Marie Passet, PharmD, Florence Rabian, MD, Ramy Rahmé, Etienne Lengline, MD, Emmanuel Raffoux, MD, Nathalie Dhedin, Aurelie Cabannes-Hamy, MD, Ilhem Rahal, Marie Sebert, MD, Wendy Cuccuini, Odile Maarek, Anna Raimbault, PhD, Stéphanie Mathis, Karine Celli-Lebras, CRA, Lionel Ades, MD PhD, Pierre Fenaux, MD PhD, Nicolas Boissel, MD PhD, Jean Soulier, Herve Dombret, MD, Emmanuelle Clappier, PhD PharmD, Raphael Itzykson, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 1537.
https://doi.org/10.1182/blood-2018-99-111288
Published: 2018