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Journal Articles

Favorable Progression-Free Survival Associated with Immune Bio-Markers Modulated By Pomalidomide in Relapsed/Refractory Multiple Myeloma: An Analysis of Phase III Study

Blood (2019) 134 (Supplement_1): 1784.

https://doi.org/10.1182/blood-2019-131257

Published: 2019

Journal Articles

Interleukin-6 Adversely Impacts Genomic Stability Via Targeting Multiple Pathways in Multiple Myeloma

Chaitanya Yenumula, MD, Srikanth Talluri, PhD, Tommaso Perini, MD, Subodh Kumar, PhD, Jialan Shi, MD PhD, Rao Prabhala, PhD, Masood A. Shammas, PhD, Nikhil Munshi, MD

Blood (2018) 132 (Supplement 1): 4467.

https://doi.org/10.1182/blood-2018-99-119346

Published: 2018

Journal Articles

Critical Role for Apobec and Its Interacting Partners in Mediating Mutations and Cell Growth in Multiple Myeloma (MM)

Srikanth Talluri, PhD, Mehmet Kemal Samur, PhD, Jialan Shi, MD PhD, Rao Prabhala, PhD, Hervé Avet-Loiseau, MD PhD, Masood A. Shammas, PhD, Nikhil Munshi, MD

Blood (2018) 132 (Supplement 1): 4462.

https://doi.org/10.1182/blood-2018-99-118441

Published: 2018

Journal Articles

Chromatin Accessibility Profiling Reveals Cis-Regulatory Heterogeneity and Novel Transcription Factor Dependencies in Multiple Myeloma

Christopher J. Ott, PhD, Raphael Szalat, MD, Matthew Lawlor, Mehmet Kemal Samur, PhD, Yan Xu, MD, Charles B Epstein, Charles Y Lin, PhD, Rao Prabhala, PhD, Nina Farrell, Lauren D Walter, Logan Schwartz, Kenneth Wen, BS, Yu-Tzu Tai, PhD, Mariateresa Fulciniti, PhD, Jinhua Wang, PhD, Nathanael Gray, PhD, Kenneth Anderson, MD, Richard A. Young, PhD, Nikhil Munshi, MD

Blood (2018) 132 (Supplement 1): 1313.

https://doi.org/10.1182/blood-2018-99-119941

Published: 2018

Journal Articles

Integrative Oncogenomic Analysis Combining Whole Genome, Transcriptome and Epigenome Identifies Altered Chromatin Accessibility Landscape in Multiple Myeloma

Raphael Szalat, MD, Mehmet Kemal Samur, PhD, Christopher J. Ott, PhD, Matthew Lawlor, Charles Epstein, Brian J Abraham, PhD, Charles Y Lin, PhD, Linying Zhang, Rao Prabhala, PhD, Nina Farrell, Kenneth Wes, Yu-Tzu Tai, PhD, Mariateresa Fulciniti, PhD, Giovanni Parmigiani, Richard A. Young, PhD, Kenneth C Anderson, MD, Nikhil Munshi, MD

Blood (2017) 130 (Supplement 1): 328.

https://doi.org/10.1182/blood.V130.Suppl_1.328.328

Published: 2017

Journal Articles

Perturbation in B Cell-Subsets Can Explain the Observed Suppression of Uninvolved Immunoglobulins and Their Impact on T Tell-Subsets As Well As Patients Outcome in Myeloma

Rao Prabhala, PhD, Shree Acharya, MS, Megan Stekla, BS, Srikanth Talluri, PhD, Raphael Szalat, MD, Puru Nanjappa, Michael A Lopez, BS, Kenneth Wen, BS, Chaitanya Yenumula, MD, Alexander Heubeck, BS, Yu-Tzu Tai, PhD, Ansh Mehta, MBBS, Mariateresa Fulciniti, PhD, Suzan Lazo-Kallanian, BS, John Daley, PhD, Paul G Richardson, MD, Kenneth C Anderson, MD, Nikhil Munshi, MD

Blood (2017) 130 (Supplement 1): 3049.

https://doi.org/10.1182/blood.V130.Suppl_1.3049.3049

Published: 2017

Journal Articles

Immune Microenvironment Contributes to Dysregulation of Aid/Apobec Expression and Genomic Instability in Multiple Myeloma

Srikanth Talluri, PhD, Mehmet Kemal Samur, PhD, Puru Nanjappa, Chaitanya Yenumula, MD, Rao Prabhala, PhD, Masood A. Shammas, PhD, Nikhil Munshi, MD

Blood (2017) 130 (Supplement 1): 4333.

https://doi.org/10.1182/blood.V130.Suppl_1.4333.4333

Published: 2017

Journal Articles

Apobec Family of Proteins Mediate Genomic Changes in Multiple Myeloma By Inducing DNA Damage and C>T Mutations

Srikanth Talluri, PhD, Mehmet Kemal Samur, PhD, Leutz Buon, Puru Nanjappa, Rao Prabhala, PhD, Masood A. Shammas, PhD, Nikhil Munshi, MD

Blood (2017) 130 (Supplement 1): 4334.

https://doi.org/10.1182/blood.V130.Suppl_1.4334.4334

Published: 2017

Journal Articles

Dysregulated Aid/Apobec Family Proteins Promote Genomic Instability in Multiple Myeloma

Srikanth Talluri, PhD, Mehmet Kemal Samur, PhD, Leutz Buon, Stekla A Megan, Purushothama Nanjappa, Rao Prabhala, PhD, Masood A. Shammas, PhD, Nikhil C. Munshi, MD

Blood (2016) 128 (22): 803.

https://doi.org/10.1182/blood.V128.22.803.803

Published: 2016

Journal Articles

Perturbation of Genomic Instability by Wortmannin in Myeloma.

Jagannath Pal, MBBS, PhD, Dheeraj Pelluru, PhD, Mariateresa Fulciniti, PhD, Samir B Amin, MBBS, Leutz Buon, PhD, Rao Prabhala, PhD, Kenneth C. Anderson, Masood A Shammas, PhD, Nikhil C. Munshi

Blood (2009) 114 (22): 1105.

https://doi.org/10.1182/blood.V114.22.1105.1105

Published: 2009

Journal Articles

Significant Biological Role of Sp1 Transactivation in Myeloma: Potential Therapeutic Application.

Mariateresa Fulciniti, PhD, Teru Hideshima, M.D., Ph.D., Puru Nanjappa, MS, Scott Rodig, M.D., Ph.D., Samir B Amin, MBBS, Dheeraj Pelluru, PhD, Jagannath Pal, Rao Prabhala, PhD, Masood A Shammas, PhD, Pierfrancesco Tassone, Scott Mohrland, Kenneth C. Anderson, MD, Nikhil C. Munshi

Blood (2009) 114 (22): 1841.

https://doi.org/10.1182/blood.V114.22.1841.1841

Published: 2009

Journal Articles

Gadolinium Containing Contrast Agent Promotes Multiple Myeloma Cell Growth: Implication for Clinical Use of MRI in Myeloma.

Mariateresa Fulciniti, PhD, Swaminathan Sundararaman, Puru Nanjappa, MS, Samir B Amin, MBBS, Prajwal Chevireddy, Neriman Gokden, PhD, Kim Hiatt, Whitney High, Masood A Shammas, PhD, Rao Prabhala, PhD, Teru Hideshima, M.D., Ph.D., Pierfrancesco Tassone, Kenneth C. Anderson, MD, Sudhir V. Shah, Nikhil C. Munshi, MD

Blood (2009) 114 (22): 1809.

https://doi.org/10.1182/blood.V114.22.1809.1809

Published: 2009

Journal Articles

TH17 Pathway Promotes Tumor Cell Growth and Suppresses Immune Function in Myeloma: Potential for Therapeutic Application

Rao Prabhala, PhD, Dheeraj Pelluru, Mariateresa Fulciniti, Puru Nanjappa, Harsha K. Prabhala, Nithya S. Prabhala, Constantine Mitsiades, Yu-Tzu Tai, Irene Ghobrial, Paul Richardson, Konstantinos Lefkimmiatis, John F. Daley, Yvonne A. Efebera, Kenneth C. Anderson, MD, Nikhil C. Munshi

Blood (2008) 112 (11): 2737.

https://doi.org/10.1182/blood.V112.11.2737.2737

Published: 2008

Journal Articles

OFD1-Mediated T Cell Responses in MGUS Patients: Implications for Immunotherapy.

Simona Blotta, MD, Rao Prabhala, PhD, Dheeraj Pelluru, PhD, Sasada Tetsuro, PhD, Brunella Franco, MD, PhD, Pierosandro Tagliaferri, MD, Pierfranceso Tassone, MD, Kenneth C. Anderson, MD, Nikhil C. Munshi, MD

Blood (2007) 110 (11): 1488.

https://doi.org/10.1182/blood.V110.11.1488.1488

Published: 2007

Journal Articles

Anti-DKK1 mAb (BHQ880) as a Potential Therapeutic for Multiple Myeloma.

Mariateresa Fulciniti, PhD, Pierfrancesco Tassone, MD, Teru Hideshima, MD, Sonia Vallet, MD, Seth Ettenberg, PhD, David Stover, PhD, Simona Blotta, MD, Zhenxin Shen, PhD, Maria Teresa Dimartino, PhD, Paola Neri, MD, Rao Prabhala, PhD, Raje Nopur, MD, Steven R. Goldring, MD, Kenneth C. Anderson, MD, Nikhil C. Munshi, MD

Blood (2007) 110 (11): 551.

https://doi.org/10.1182/blood.V110.11.551.551

Published: 2007

Journal Articles

Induction of UBC9 and the Sumoylation Pathway in Multiple Myeloma Promotes Plasma Cell Growth and Correlates with Decreased Patient Survival.

James J. Driscoll, MD, PhD, Konstantinos Lefkimmiatis, PhD, Mariateresa Fulciniti, PhD, Rao Prabhala, PhD, Dheeraj Pelluru, PhD, Philip R. Greipp, MD, Nikhil C. Munshi, MD

Blood (2007) 110 (11): 3516.

https://doi.org/10.1182/blood.V110.11.3516.3516

Published: 2007

Journal Articles

T H 17 Pathway and Associated Pro-Inflammatory Cytokines Promote Immune Dysfunction in Myeloma.

Rao Prabhala, PhD, Dheeraj Pelluru, PhD, Paola Neri, MD, Mariateresa Fulciniti, PhD, James J. Driscoll, MD, PhD, Song Weihua, MD, Simona Blotta, MD, Yu-Tzu Tai, PhD, Hiren Patel, BS, Yvonne A. Efebera, MD, Teru Hideshima, MD, PhD, Dhaminder Chauhan, PhD, John F. Daley, PhD, Kenneth C. Anderson, MD, Nikhil C. Munshi, MD

Blood (2007) 110 (11): 3517.

https://doi.org/10.1182/blood.V110.11.3517.3517

Published: 2007

Journal Articles

Hedgehog Pathway as a Potential Therapeutic Target in Multiple Myeloma.

Simona Blotta, MD, Joeseph Negri, Purushothama Nanjappa, Anne-Sophie Moreau, MD, Rao Prabhala, PhD, Masood Shammas, PhD, Dheeraj Pelluru, PhD, Douglas McMillin, PhD, Yu-Tzu Tai, PhD, Pierfrancesco Tassone, MD, Kenneth C. Anderson, MD, Constantine Mitsiades, MD, PhD, Nikhil C. Munshi, MD

Blood (2007) 110 (11): 672.

https://doi.org/10.1182/blood.V110.11.672.672

Published: 2007

Journal Articles

DNA Damage Induced Sumoylation of p53 in Multiple Myeloma: Implications for Cell Proliferation and Apoptosis.

James J. Driscoll, MD, PhD, Dheeraj Pelluru, PhD, Rao Prabhala, PhD, Konstantinos Lefkimmiatis, PhD, Mariateresa Fulciniti, PhD, Nikhil C. Munshi, MD

Blood (2007) 110 (11): 112.

https://doi.org/10.1182/blood.V110.11.112.112

Published: 2007

Journal Articles

Novel Murine Model To Study Modulation of Genes and Molecular Pathways Induced Following In Vivo Interaction between Multiple Myeloma Cells and Human BM Milieu.

Paola Neri, MD, Pierfrancesco Tassone, MD, Masood Shammas, PhD, Mariateresa Fulciniti, PhD, Yu-Tzu Tai, PhD, Simona Blotta, MD, Rao Prabhala, PhD, Mariateresa Di Martino, PhD, Laurence Catley, MD, Pierosandro Tagliaferri, MD, Salvatore Venuta, MD, Ruben Carrasco, MD, Kenneth C. Anderson, MD, Nikhil C. Munshi, MD

Blood (2006) 108 (11): 3409.

https://doi.org/10.1182/blood.V108.11.3409.3409

Published: 2006

NARROW

Favorable Progression-Free Survival Associated with Immune Bio-Markers Modulated By Pomalidomide in Relapsed/Refractory Multiple Myeloma: An Analysis of Phase III Study

Interleukin-6 Adversely Impacts Genomic Stability Via Targeting Multiple Pathways in Multiple Myeloma

Critical Role for Apobec and Its Interacting Partners in Mediating Mutations and Cell Growth in Multiple Myeloma (MM)

Chromatin Accessibility Profiling Reveals Cis-Regulatory Heterogeneity and Novel Transcription Factor Dependencies in Multiple Myeloma

Integrative Oncogenomic Analysis Combining Whole Genome, Transcriptome and Epigenome Identifies Altered Chromatin Accessibility Landscape in Multiple Myeloma

Perturbation in B Cell-Subsets Can Explain the Observed Suppression of Uninvolved Immunoglobulins and Their Impact on T Tell-Subsets As Well As Patients Outcome in Myeloma

Immune Microenvironment Contributes to Dysregulation of Aid/Apobec Expression and Genomic Instability in Multiple Myeloma

Apobec Family of Proteins Mediate Genomic Changes in Multiple Myeloma By Inducing DNA Damage and C>T Mutations

Dysregulated Aid/Apobec Family Proteins Promote Genomic Instability in Multiple Myeloma

Perturbation of Genomic Instability by Wortmannin in Myeloma.

Significant Biological Role of Sp1 Transactivation in Myeloma: Potential Therapeutic Application.

Gadolinium Containing Contrast Agent Promotes Multiple Myeloma Cell Growth: Implication for Clinical Use of MRI in Myeloma.

TH17 Pathway Promotes Tumor Cell Growth and Suppresses Immune Function in Myeloma: Potential for Therapeutic Application

OFD1-Mediated T Cell Responses in MGUS Patients: Implications for Immunotherapy.

Anti-DKK1 mAb (BHQ880) as a Potential Therapeutic for Multiple Myeloma.

Induction of UBC9 and the Sumoylation Pathway in Multiple Myeloma Promotes Plasma Cell Growth and Correlates with Decreased Patient Survival.

T H 17 Pathway and Associated Pro-Inflammatory Cytokines Promote Immune Dysfunction in Myeloma.

Hedgehog Pathway as a Potential Therapeutic Target in Multiple Myeloma.

DNA Damage Induced Sumoylation of p53 in Multiple Myeloma: Implications for Cell Proliferation and Apoptosis.

Novel Murine Model To Study Modulation of Genes and Molecular Pathways Induced Following In Vivo Interaction between Multiple Myeloma Cells and Human BM Milieu.

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American Society of Hematology

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American Society of Hematology

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