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Journal Articles

Multiple Myeloma Cells Express IL-17A Creating An Autocrine Loop: An Attractive Therapeutic Target

Rao H. Prabhala, Ph.D., Mariateresa Fulcinitti, PhD, Dheeraj Pelluru, PhD, Harsha K. Prabhala, MS, Naim Rashid, PhD, Adam Sperling, MD, PhD, Puru Nanjappa, MS, Saem Lee, B.A., Andreea Negroiu, MD, Suzan Lazo-Kallanian, BS, Aditya Munshi, MD, Paul G. Richardson, MD, John Daley, PhD, Kenneth C. Anderson, MD, Nikhil C. Munshi, MD

Blood (2013) 122 (21): 3113.

https://doi.org/10.1182/blood.V122.21.3113.3113

Published: 2013

Journal Articles

Interleukin-17 and T H 17 Pathway Supports Waldenstrom's Macroglobulinemia Cell-Growth: Potential Therapeutic Implications

Rao H Prabhala, Ph.D., Dheeraj Pelluru, PhD, Mariateresa Fulciniti, PhD, Puru Nanjappa, MS, Christine Pai, BS, Saem Lee, B.A., Nithya Prabhala, John Daley, PhD, Steven P. Treon, MD, PhD, Nikhil C. Munshi, MD

Blood (2010) 116 (21): 446.

https://doi.org/10.1182/blood.V116.21.446.446

Published: 2010

Journal Articles

Human Monoclonal Antibody Targeting IL-17A (AIN457) Down-Regulates MM Cell-Growth and Survival and Inhibits Osteoclast Development In Vitro and In Vivo: A Potential Novel Therapeutic Application In Myeloma

Rao H Prabhala, PH.D., Mariateresa Fulciniti, PhD, Dheeraj Pelluru, PhD, Puru Nanjappa, MS, Christine Pai, BS, Saem Lee, B.A., Nithya Prabhala, Weihua Song, MD, Constantine S. Mitsiades, MD, PhD, Konstantinos Lefkimmiatis, PhD, Yu-Tzu Tai, PhD, Irene Ghobrial, MD, Paul Richardson, MD, John Daley, Kenneth C. Anderson, MD, Seth Ettenberg, Franco Di Padova, Nikhil C. Munshi, MD

Blood (2010) 116 (21): 456.

https://doi.org/10.1182/blood.V116.21.456.456

Published: 2010

Journal Articles

Elevated IL-17 produced by Th17 cells promotes myeloma cell growth and inhibits immune function in multiple myeloma

Rao H. Prabhala, Dheeraj Pelluru, Mariateresa Fulciniti, Harsha K. Prabhala, Puru Nanjappa, Weihua Song, Christine Pai, Samir Amin, Yu-Tzu Tai, Paul G. Richardson, Irene M. Ghobrial, Steven P. Treon, John F. Daley, Kenneth C. Anderson, Jeffery L. Kutok, Nikhil C. Munshi

Blood (2010) 115 (26): 5385–5392.

https://doi.org/10.1182/blood-2009-10-246660

Published: 2010

Journal Articles

The sumoylation pathway is dysregulated in multiple myeloma and is associated with adverse patient outcome

James J. Driscoll, Dheeraj Pelluru, Konstantinos Lefkimmiatis, Mariateresa Fulciniti, Rao H. Prabhala, Philip R. Greipp, Bart Barlogie, Yu-Tzu Tai, Kenneth C. Anderson, John D. Shaughnessy, Jr, Christina M. Annunziata, Nikhil C. Munshi

Blood (2010) 115 (14): 2827–2834.

https://doi.org/10.1182/blood-2009-03-211045

Published: 2010

Includes: Supplemental data

Journal Articles

Significant Biological Role of Sp1 Transactivation in Myeloma: Potential Therapeutic Application.

Mariateresa Fulciniti, PhD, Teru Hideshima, M.D., Ph.D., Puru Nanjappa, MS, Scott Rodig, M.D., Ph.D., Samir B Amin, MBBS, Dheeraj Pelluru, PhD, Jagannath Pal, Rao Prabhala, PhD, Masood A Shammas, PhD, Pierfrancesco Tassone, Scott Mohrland, Kenneth C. Anderson, MD, Nikhil C. Munshi

Blood (2009) 114 (22): 1841.

https://doi.org/10.1182/blood.V114.22.1841.1841

Published: 2009

Journal Articles

Perturbation of Genomic Instability by Wortmannin in Myeloma.

Jagannath Pal, MBBS, PhD, Dheeraj Pelluru, PhD, Mariateresa Fulciniti, PhD, Samir B Amin, MBBS, Leutz Buon, PhD, Rao Prabhala, PhD, Kenneth C. Anderson, Masood A Shammas, PhD, Nikhil C. Munshi

Blood (2009) 114 (22): 1105.

https://doi.org/10.1182/blood.V114.22.1105.1105

Published: 2009

Journal Articles

Lack of Response to Vaccination in MGUS and Stable Myeloma.

Rao H Prabhala, PhD, Yvonne A Efebera, MD, Saem Lee, Andrew J Han, Dheeraj Pelluru, Puru Nanjappa, MS, Samir Amin, Christine Pai, Irene Ghobrial, M.D., Robert L Schlossman, M.D., Ph.D., Jacob Laubach, Mariateresa Fulciniti, Paul Richardson, M.D., Ph.D., Kenneth C. Anderson, MD, Nikhil C. Munshi, MD

Blood (2009) 114 (22): 1852.

https://doi.org/10.1182/blood.V114.22.1852.1852

Published: 2009

Journal Articles

TH17 Pathway Promotes Tumor Cell Growth and Suppresses Immune Function in Myeloma: Potential for Therapeutic Application

Rao Prabhala, PhD, Dheeraj Pelluru, Mariateresa Fulciniti, Puru Nanjappa, Harsha K. Prabhala, Nithya S. Prabhala, Constantine Mitsiades, Yu-Tzu Tai, Irene Ghobrial, Paul Richardson, Konstantinos Lefkimmiatis, John F. Daley, Yvonne A. Efebera, Kenneth C. Anderson, MD, Nikhil C. Munshi

Blood (2008) 112 (11): 2737.

https://doi.org/10.1182/blood.V112.11.2737.2737

Published: 2008

Journal Articles

Oncoprotein 18 (Op18) : A Differentially Expressed Gene Is a Novel Therapeutic Target in Multiple Myeloma

Dheeraj Pelluru, Jingyi Wang, Rao Prabhala, Mariateresa Fulciniti, Masood A. Shammas, Samirkumar B Amin, MBBS, Kenneth C. Anderson, Nikhil C. Munshi

Blood (2008) 112 (11): 2741.

https://doi.org/10.1182/blood.V112.11.2741.2741

Published: 2008

Journal Articles

Induction of UBC9 and the Sumoylation Pathway in Multiple Myeloma Promotes Plasma Cell Growth and Correlates with Decreased Patient Survival.

James J. Driscoll, MD, PhD, Konstantinos Lefkimmiatis, PhD, Mariateresa Fulciniti, PhD, Rao Prabhala, PhD, Dheeraj Pelluru, PhD, Philip R. Greipp, MD, Nikhil C. Munshi, MD

Blood (2007) 110 (11): 3516.

https://doi.org/10.1182/blood.V110.11.3516.3516

Published: 2007

Journal Articles

T H 17 Pathway and Associated Pro-Inflammatory Cytokines Promote Immune Dysfunction in Myeloma.

Rao Prabhala, PhD, Dheeraj Pelluru, PhD, Paola Neri, MD, Mariateresa Fulciniti, PhD, James J. Driscoll, MD, PhD, Song Weihua, MD, Simona Blotta, MD, Yu-Tzu Tai, PhD, Hiren Patel, BS, Yvonne A. Efebera, MD, Teru Hideshima, MD, PhD, Dhaminder Chauhan, PhD, John F. Daley, PhD, Kenneth C. Anderson, MD, Nikhil C. Munshi, MD

Blood (2007) 110 (11): 3517.

https://doi.org/10.1182/blood.V110.11.3517.3517

Published: 2007

Journal Articles

DNA Damage Induced Sumoylation of p53 in Multiple Myeloma: Implications for Cell Proliferation and Apoptosis.

James J. Driscoll, MD, PhD, Dheeraj Pelluru, PhD, Rao Prabhala, PhD, Konstantinos Lefkimmiatis, PhD, Mariateresa Fulciniti, PhD, Nikhil C. Munshi, MD

Blood (2007) 110 (11): 112.

https://doi.org/10.1182/blood.V110.11.112.112

Published: 2007

Journal Articles

OFD1-Mediated T Cell Responses in MGUS Patients: Implications for Immunotherapy.

Simona Blotta, MD, Rao Prabhala, PhD, Dheeraj Pelluru, PhD, Sasada Tetsuro, PhD, Brunella Franco, MD, PhD, Pierosandro Tagliaferri, MD, Pierfranceso Tassone, MD, Kenneth C. Anderson, MD, Nikhil C. Munshi, MD

Blood (2007) 110 (11): 1488.

https://doi.org/10.1182/blood.V110.11.1488.1488

Published: 2007

Journal Articles

Hedgehog Pathway as a Potential Therapeutic Target in Multiple Myeloma.

Simona Blotta, MD, Joeseph Negri, Purushothama Nanjappa, Anne-Sophie Moreau, MD, Rao Prabhala, PhD, Masood Shammas, PhD, Dheeraj Pelluru, PhD, Douglas McMillin, PhD, Yu-Tzu Tai, PhD, Pierfrancesco Tassone, MD, Kenneth C. Anderson, MD, Constantine Mitsiades, MD, PhD, Nikhil C. Munshi, MD

Blood (2007) 110 (11): 672.

https://doi.org/10.1182/blood.V110.11.672.672

Published: 2007

NARROW

Multiple Myeloma Cells Express IL-17A Creating An Autocrine Loop: An Attractive Therapeutic Target

Interleukin-17 and T H 17 Pathway Supports Waldenstrom's Macroglobulinemia Cell-Growth: Potential Therapeutic Implications

Human Monoclonal Antibody Targeting IL-17A (AIN457) Down-Regulates MM Cell-Growth and Survival and Inhibits Osteoclast Development In Vitro and In Vivo: A Potential Novel Therapeutic Application In Myeloma

Elevated IL-17 produced by Th17 cells promotes myeloma cell growth and inhibits immune function in multiple myeloma

The sumoylation pathway is dysregulated in multiple myeloma and is associated with adverse patient outcome

Significant Biological Role of Sp1 Transactivation in Myeloma: Potential Therapeutic Application.

Perturbation of Genomic Instability by Wortmannin in Myeloma.

Lack of Response to Vaccination in MGUS and Stable Myeloma.

TH17 Pathway Promotes Tumor Cell Growth and Suppresses Immune Function in Myeloma: Potential for Therapeutic Application

Oncoprotein 18 (Op18) : A Differentially Expressed Gene Is a Novel Therapeutic Target in Multiple Myeloma

Induction of UBC9 and the Sumoylation Pathway in Multiple Myeloma Promotes Plasma Cell Growth and Correlates with Decreased Patient Survival.

T H 17 Pathway and Associated Pro-Inflammatory Cytokines Promote Immune Dysfunction in Myeloma.

DNA Damage Induced Sumoylation of p53 in Multiple Myeloma: Implications for Cell Proliferation and Apoptosis.

OFD1-Mediated T Cell Responses in MGUS Patients: Implications for Immunotherapy.

Hedgehog Pathway as a Potential Therapeutic Target in Multiple Myeloma.

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American Society of Hematology

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American Society of Hematology

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