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Journal Articles

CXCL12 Knock-out Enhances Leukemia Stem Cell Response to Combination Chemotherapy Plus Tyrosine Kinase Inhibition in Flt3-ITD Acute Myeloid Leukemia

Nick R Anderson, BS, Hui Li, BS, Mason W Harris, Shaowei Qiu, MD, Amanda K Mullen, Andrew J Paterson, PhD, Ravi Bhatia, MD

Blood (2020) 136 (Supplement 1): 7–8.

https://doi.org/10.1182/blood-2020-142579

Published: 2020

Journal Articles

Pricing of First and Second Generation Tyrosine Kinase Inhibitors (TKIs) Pre- and Post-Transition of Imatinib to Generic Status

Kelly Kenzik, PhD, Ravi Bhatia, MD, Smita Bhatia, MDMPH

Blood (2019) 134 (Supplement_1): 2140.

https://doi.org/10.1182/blood-2019-123490

Published: 2019

Journal Articles

Role of Autophagy in Resistance of FLT3-ITD AML Stem Cells to FLT3 TKI Treatment

Shaowei Qiu, MD, Chengcheng Yan, MD, Andrew J Paterson, PhD, Hui Li, BS, Nick Anderson, BS, Ajay Abraham, PhD, Jianbo He, MD, Mansi Shah, PhD, Puneet Agarwal, Jing Yang, PhD, Min Xie, MD, Rui Lu, PhD, Rob S. Welner, PhD, Ravi Bhatia, MD

Blood (2019) 134 (Supplement_1): 2548.

https://doi.org/10.1182/blood-2019-124948

Published: 2019

Journal Articles

Preliminary Results from a Phase 1 First-in-Human Study of AMG 673, a Novel Half-Life Extended (HLE) Anti-CD33/CD3 BiTE ® (Bispecific T-Cell Engager) in Patients with Relapsed/Refractory (R/R) Acute Myeloid Leukemia (AML)

Marion Subklewe, MD, Anthony Stein, MD, Roland B. Walter, MD PhD MS, Ravi Bhatia, MD, Andrew H. Wei, PhD FRACP, FRCPA, MBBS, David Ritchie, MD PhD, Veit Bücklein, MD, Pankit Vachhani, MD, Tian Dai, PhD, Antreas Hindoyan, PhD, Suresh Agarwal, PhD, Abraham Anderson, Sophia Khaldoyanidi, MD PhD, Farhad Ravandi, MD

Blood (2019) 134 (Supplement_1): 833.

https://doi.org/10.1182/blood-2019-127977

Published: 2019

Journal Articles

An Epigenetic Screen Identifies PRMT5 As a Target for Inhibition of FLT3-ITD AML Cell Growth in Combination with Tyrosine Kinase Inhibitors

Aditi Dhir, MD, Andrew J Paterson, PhD, Shaowei Qiu, MD, Amanda K Mullen, Nick R Anderson, BS, Ravi Bhatia, MD

Blood (2019) 134 (Supplement_1): 2524.

https://doi.org/10.1182/blood-2019-125178

Published: 2019

Journal Articles

Identifying the Leukemia Stem Cell Niche Mediating Drug Resistance in Flt3-ITD Acute Myeloid Leukemia

Nick R Anderson, BS, Hui Li, BS, Mason W Harris, Shaowei Qiu, MD, Andrew J Paterson, PhD, Ravi Bhatia, MD

Blood (2019) 134 (Supplement_1): 909.

https://doi.org/10.1182/blood-2019-124379

Published: 2019

Journal Articles

TNF-α-Induced Bone Marrow Stromal Progenitor Alterations Enhance Leukemic Stem Cell Growth and Treatment Resistance Via Increased CXCL1-CXCR2 Signaling

Puneet Agarwal, Hui Li, BS, Kwangmin Choi, PhD, Robert S. Welner, PhD, Jianbo He, MD, Ravi Bhatia, MD

Blood (2018) 132 (Supplement 1): 875.

https://doi.org/10.1182/blood-2018-99-117801

Published: 2018

Journal Articles

SIRT1 Mediates Enhanced Mitochondrial Oxidative Phosphorylation in Chronic Myelogenous Leukemia Stem Cells

Ajay Abraham, PhD, Shaowei Qiu, MD, Balu K Chacko, PhD, Hui Li, BS, Andrew J Paterson, PhD, Jianbo He, MD, Puneet Agarwal, PhD, Mansi Shah, PhD, Robert S. Welner, PhD, Victor M Darley-Usmar, PhD, Ravi Bhatia, MD

Blood (2018) 132 (Supplement 1): 932.

https://doi.org/10.1182/blood-2018-99-115709

Published: 2018

Journal Articles

Health Care and out-of-Pocket (OOP) Costs Among Medicare Beneficiaries Diagnosed with Chronic Myeloid Leukemia (CML)

Kelly Kenzik, PhD, Ravi Bhatia, MD, Grant R Williams, Smita Bhatia, MD MPH

Blood (2018) 132 (Supplement 1): 4730.

https://doi.org/10.1182/blood-2018-99-110742

Published: 2018

Journal Articles

Role of Enhanced Autophagy in Resistance of FLT3-ITD AML Stem Cells to FLT3 TKI Treatment

Shaowei Qiu, MD, Andrew J Paterson, PhD, Ajay Abraham, PhD, Jianbo He, MD, Mansi Shah, PhD, Puneet Agarwal, PhD, Amanda K Mullen, Hui Li, BS, Mason W Harris, Nicholas R Anderson, Ravi Bhatia, MD

Blood (2018) 132 (Supplement 1): 1358.

https://doi.org/10.1182/blood-2018-99-115702

Published: 2018

Journal Articles

Standard Processing of Apheresis Products for HSCT Provides Significant Cost Savings over Automated Processing without Impact on Time or Product Quality

Lauren Bongo, MLS, Ravi Bhatia, MD, Lawrence S. Lamb, Jr., PhD

Blood (2018) 132 (Supplement 1): 5693.

https://doi.org/10.1182/blood-2018-99-119295

Published: 2018

Journal Articles

Characterization of Novel Subtypes in B Progenitor Acute Lymphoblastic Leukemia

Zhaohui Gu, PhD, Michelle L. Churchman, PhD, Kathryn G. Roberts, PhD, Ian Moore, MS, Xin Zhou, PhD, Joy Nakitandwe, PhD, Kohei Hagiwara, MD, Stephane Pelletier, PhD, Sebastian Gingras, PhD, Hartmut Berns, PhD, Debbie Payne-Turner, Ashley Hill, BS, Ilaria Iacobucci, PhD, Lei Shi, PhD, Stanley Pounds, PhD, Cheng Cheng, PhD, Deqing Pei, MS, Chunxu Qu, PhD, Meenakshi Devidas, PhD, Yunfeng Dai, PhD, Shalini C. Reshmi, PhD, Julie Gastier Foster, PhD, Elizabeth A. Raetz, MD, Michael J. Borowitz, MD PhD, Brent Wood, MD PhD, William L. Carroll, MD, Patrick Zweider McKay, MD PhD, Karen R. Rabin, MD PhD, Leonard A. Mattano, MD, Kelly W. Maloney, MD, Alessandro Rambaldi, MD PhD, Orietta Spinelli, PhD, Jerald Radich, MD, Mark D. Minden, MD PhD, Jacob M. Rowe, MD, Selina Luger, MD, Mark R. Litzow, MD, Martin S. Tallman, MD, Janis Recevskis, PhD, Yanming Zhang, Ravi Bhatia, MD, Jessica Kohlschmidt, PhD, Krzysztof Mrózek, MDPhD, Clara D. Bloomfield, MD, Wendy Stock, MD, Steven M. Kornblau, MD, Hagop M. Kantarjian, MD, Marina Y. Konopleva, MD PhD, William E. Evans, PharmD, Sima Jeha, MD, Ching-Hon Pui, MD, Jun J. Yang, PhD, Elisabeth M. Paietta, PhD, James R. Downing, MD, Mary V Relling, PharmD, Jinghui Zhang, Mignon L. Loh, MD, Stephen P. Hunger, MD, Charles G. Mullighan, MBBS, MD

Blood (2018) 132 (Supplement 1): 565.

https://doi.org/10.1182/blood-2018-99-111219

Published: 2018

Journal Articles

CXCR4 Has a CXCL12-Independent Essential Role in MLL-AF9 Driven Acute Myeloid Leukemia

Ramprasad Ramakrishnan, Pablo Peña-Martínez, Puneet Agarwal, PhD, Carl Högberg, PhD, Marion Chapellier, PhD, Mansi Shah, PhD, Björn Nilsson, MD PhD, Benjamin L. Ebert, MDPhD, Ravi Bhatia, MD, Marcus Järås, PhD

Blood (2018) 132 (Supplement 1): 774.

https://doi.org/10.1182/blood-2018-99-116137

Published: 2018

Journal Articles

Association of Gene Expression Patterns in Bone Marrow Cells with Likelihood of Treatment Free Remission after TKI Discontinuation

Jianbo He, MD, Sahee Park, Soo Young Choi, David Crossman, Bin Zhang, PhD, Puneet Agarwal, PhD, Andrew Zhang, Su Chu, MD, Dong-Wook Kim, MD PhD, Ravi Bhatia, MD

Blood (2018) 132 (Supplement 1): 1721.

https://doi.org/10.1182/blood-2018-99-114137

Published: 2018

Journal Articles

Genomic Determinants of Response to Blinatumomab in Relapsed/Refractory (R/R) B-Cell Precursor Acute Lymphoblastic Leukemia in Adults

Yaqi Zhao, MSc, Ibrahim Aldoss, MD, Chunxu Qu, PhD, Guido Marcucci, Anthony S. Stein, MD, Ravi Bhatia, MD, Charles G. Mullighan, MBBS, MD, Stephen J Forman, Kathryn G. Roberts, PhD

Blood (2018) 132 (Supplement 1): 1552.

https://doi.org/10.1182/blood-2018-99-113604

Published: 2018

Journal Articles

Activation of SIRT1 Deacetylase As a Therapeutic Approach for Myelodysplastic Syndromes By Restoring TET2 Function

Blood (2017) 130 (Supplement 1): 2497.

https://doi.org/10.1182/blood.V130.Suppl_1.2497.2497

Published: 2017

Journal Articles

Hoxa9 and Hoxa10 Induce CML Myeloid Blast Crisis Development through Activation of Myb Expression

Vijay Negi, PhD, Bandana Ajay Vishwakarma, BSc, MSc, PhD, Su Chu, MD, Kevin Oakley, Yufen Han, Ravi Bhatia, MD, Yang Du, PhD

Blood (2017) 130 (Supplement 1): 2865.

https://doi.org/10.1182/blood.V130.Suppl_1.2865.2865

Published: 2017

Journal Articles

Role of SCF-Expressing Bone Marrow Populations in Hematopoietic and Leukemic Stem Cell Regulation

Mansi Shah, PhD BSc, Hui Li, BS, Mason Harris, Jianbo He, MD, Andrew J Paterson, PhD, Ravi Bhatia, MD

Blood (2017) 130 (Supplement 1): 2439.

https://doi.org/10.1182/blood.V130.Suppl_1.2439.2439

Published: 2017

Journal Articles

CXCL12-Expressing Bone Marrow Niches Differentially Regulate CML Compared to Normal Stem Cells

Puneet Agarwal, Hui Li, BS, Andrew J Paterson, PhD, Jianbo He, MD, Takashi Nagasawa, MD PhD, Ravi Bhatia, MD

Blood (2017) 130 (Supplement 1): 1584.

https://doi.org/10.1182/blood.V130.Suppl_1.1584.1584

Published: 2017

Journal Articles

Decline in Late Mortality after Allogeneic Blood or Marrow Transplantation (alloBMT) Performed in Childhood: a Report from the BMT Survivor Study-2 (BMTSS-2)

Anna Sallfors Holmqvist, MD PhD, Yanjun Chen, MS, Jessica Wu, BA, Lindsey Hageman, MPH, Liton F. Francisco, BS, Mariel Parman, MPH, Michelle Kung, MA, Emily Ness, MPH, Kevin D. Battles, BS, Ravi Bhatia, MD, Donna Salzman, MD, Jeanette Falck Winther, MD DMSc, Stephen J. Forman, MD, Joseph Rosenthal, MD MS, Daniel J. Weisdorf, MD, Saro H. Armenian, DO,MPH, Mukta Arora, MD, Smita Bhatia, MDMPH

Blood (2017) 130 (Supplement 1): 672.

https://doi.org/10.1182/blood.V130.Suppl_1.672.672

Published: 2017

NARROW

CXCL12 Knock-out Enhances Leukemia Stem Cell Response to Combination Chemotherapy Plus Tyrosine Kinase Inhibition in Flt3-ITD Acute Myeloid Leukemia

Pricing of First and Second Generation Tyrosine Kinase Inhibitors (TKIs) Pre- and Post-Transition of Imatinib to Generic Status

Role of Autophagy in Resistance of FLT3-ITD AML Stem Cells to FLT3 TKI Treatment

Preliminary Results from a Phase 1 First-in-Human Study of AMG 673, a Novel Half-Life Extended (HLE) Anti-CD33/CD3 BiTE ® (Bispecific T-Cell Engager) in Patients with Relapsed/Refractory (R/R) Acute Myeloid Leukemia (AML)

An Epigenetic Screen Identifies PRMT5 As a Target for Inhibition of FLT3-ITD AML Cell Growth in Combination with Tyrosine Kinase Inhibitors

Identifying the Leukemia Stem Cell Niche Mediating Drug Resistance in Flt3-ITD Acute Myeloid Leukemia

TNF-α-Induced Bone Marrow Stromal Progenitor Alterations Enhance Leukemic Stem Cell Growth and Treatment Resistance Via Increased CXCL1-CXCR2 Signaling

SIRT1 Mediates Enhanced Mitochondrial Oxidative Phosphorylation in Chronic Myelogenous Leukemia Stem Cells

Health Care and out-of-Pocket (OOP) Costs Among Medicare Beneficiaries Diagnosed with Chronic Myeloid Leukemia (CML)

Role of Enhanced Autophagy in Resistance of FLT3-ITD AML Stem Cells to FLT3 TKI Treatment

Standard Processing of Apheresis Products for HSCT Provides Significant Cost Savings over Automated Processing without Impact on Time or Product Quality

Characterization of Novel Subtypes in B Progenitor Acute Lymphoblastic Leukemia

CXCR4 Has a CXCL12-Independent Essential Role in MLL-AF9 Driven Acute Myeloid Leukemia

Association of Gene Expression Patterns in Bone Marrow Cells with Likelihood of Treatment Free Remission after TKI Discontinuation

Genomic Determinants of Response to Blinatumomab in Relapsed/Refractory (R/R) B-Cell Precursor Acute Lymphoblastic Leukemia in Adults

Activation of SIRT1 Deacetylase As a Therapeutic Approach for Myelodysplastic Syndromes By Restoring TET2 Function

Hoxa9 and Hoxa10 Induce CML Myeloid Blast Crisis Development through Activation of Myb Expression

Role of SCF-Expressing Bone Marrow Populations in Hematopoietic and Leukemic Stem Cell Regulation

CXCL12-Expressing Bone Marrow Niches Differentially Regulate CML Compared to Normal Stem Cells

Decline in Late Mortality after Allogeneic Blood or Marrow Transplantation (alloBMT) Performed in Childhood: a Report from the BMT Survivor Study-2 (BMTSS-2)

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American Society of Hematology

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