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Journal Articles

Nuclear NPM-ALK Protects Myc from Proteosomal Degradation and Contributes to High Protein Expression in Cancer Stem-like Cells in ALK-Positive Anaplastic Large Cell Lymphoma

Chuquan Shang, Will Chen, Justine Lai, Moinul Haque, Peng Wang, Raymond Lai

Blood (2022) 140 (Supplement 1): 6452.

https://doi.org/10.1182/blood-2022-170670

Published: 2022

Journal Articles

The Application of the SORE6 Reporter in the Studies of Acute Myeloid Leukemia - a Novel Model for Disease Relapses

Justine Lai, Joseph Brandwein, Chuquan Shang, Will Chen, Michael P. Chu, Irwindeep Sandhu, Raymond Lai, Peng Wang

Blood (2022) 140 (Supplement 1): 9155.

https://doi.org/10.1182/blood-2022-159216

Published: 2022

Journal Articles

Epidemiology of Post-Transplant Lymphoproliferative Disorders in Children with Solid Organ Transplant over 34 Years of a Single Center Experience

Marta Rojas Vasquez, MD FRCPC, Anthea Peters, MSc, MD FRCPC, Raymond Lai, MD PhD FRCP, Curtis Mabilangan, MSc, Burton Catherine, MD FRCPC, Jutta Preiksaitis, MDFRCPC

Blood (2019) 134 (Supplement_1): 1602.

https://doi.org/10.1182/blood-2019-125344

Published: 2019

Journal Articles

The Identification of Novel Epigenetic Therapies for ALK-Driven Haematological Malignancies

Stephen P. Ducray, BSc, Ricky Trigg, PhD, Andrew J. Bannister, PhD, Raymond Lai, MD PhD FRCP, Gerda Egger, PhD, Olaf Merkel, PhD, Lukas Kenner, MD, Suzanne Turner, PhD

Blood (2019) 134 (Supplement_1): 1483.

https://doi.org/10.1182/blood-2019-125648

Published: 2019

Journal Articles

FOXM1 and the NPM-ALK/STAT3 Axis Form a Novel Positive Feedback Loop in Promoting the Oncogenesis of ALK-Positive Anaplastic Large Cell Lymphoma

Peng Wang, MD PhD, Moinul Haque, Jing Li, Yung-Hsing Huang, Meaad Almowaled, Carter Bargar, Adam Karpf, Will Chen, Suzanne Turner, Raymond Lai, PhD MD

Blood (2018) 132 (Supplement 1): 3921.

https://doi.org/10.1182/blood-2018-99-115743

Published: 2018

Journal Articles

Monomorphic Post Transplant Lymphoproliferative Disorder (Diffuse Large B Cell Lymphoma subtype) Successfully Treated without Chemotherapy after Solid Organ Transplant in Children

Marta Rojas Vasquez, MD FRCPC, Sunil J. Desai, MRCP, FRCPC, BM, BCh, Anthea Peters, MSc, MD FRCPC, Simon Urschel, MDFAKJ, Jason Yap, MDFRCPC, Raymond Lai, PhD MD, Catherine Morgan, MDFRCPC, Jutta Preiksaitis, MDFRCPC

Blood (2017) 130 (Supplement 1): 1579.

https://doi.org/10.1182/blood.V130.Suppl_1.1579.1579

Published: 2017

Journal Articles

CD3 T-Cell Infiltrates at Diagnosis Predicts Overall Survival in Solid Organ Transplant Recipients with Post-Transplant Lymphoproliferative Disorders (PTLD)

Ryan J. Stubbins, MD BSc, James Zhu, BSc, MD, Raymond Lai, MD PhD, Carolyn J. Owen, MD MDes(UK), FRCPC, Jutta Preiksaitis, MD FRCPC, Anthea C Peters, MD M.Sc., FRCPC

Blood (2016) 128 (22): 1873.

https://doi.org/10.1182/blood.V128.22.1873.1873

Published: 2016

Journal Articles

Morphologic Evolution in Post-Transplant Lymphoproliferative Disorders (PTLD): A Clinicopathologic Case Series

Ryan J. Stubbins, MD BSc, Anthea C Peters, MD M.Sc., FRCPC, Mabilang Curtis, BSc, Carolyn Owen, MD, Adnan Mansoor, MD FRCPC, Raymond Lai, MD PhD, Jutta Preiksaitis, MD FRCPC

Blood (2015) 126 (23): 5008.

https://doi.org/10.1182/blood.V126.23.5008.5008

Published: 2015

Journal Articles

STAT1 is phosphorylated and downregulated by the oncogenic tyrosine kinase NPM-ALK in ALK-positive anaplastic large-cell lymphoma

Chengsheng Wu, Ommoleila Molavi, Haifeng Zhang, Nidhi Gupta, Abdulraheem Alshareef, Kathleen M. Bone, Keshav Gopal, Fang Wu, Jamie T. Lewis, Donna N. Douglas, Norman M. Kneteman, Raymond Lai

Blood (2015) 126 (3): 336–345.

https://doi.org/10.1182/blood-2014-10-603738

Published: 2015

Includes: Supplemental data

Journal Articles

A 7-Gene Microrna Signature Characteristic of Mantle Cell Lymphoma Reveals Focal Adhesion and Integrin Signalling, Proteasome-Mediated Degradation, and the PI3K Signalling Cascade As Important to MCL Pathogenesis

Blood (2012) 120 (21): 1586.

https://doi.org/10.1182/blood.V120.21.1586.1586

Published: 2012

Journal Articles

Constitutive activation of metalloproteinase ADAM10 in mantle cell lymphoma promotes cell growth and activates the TNFα/NFκB pathway

Hanan Armanious, Pascal Gelebart, Mona Anand, Andrew Belch, Raymond Lai

Blood (2011) 117 (23): 6237–6246.

https://doi.org/10.1182/blood-2010-10-313940

Published: 2011

Includes: Supplemental data

Journal Articles

Comparing MicroRNA Expression In Aggressive and Indolent Non-Hodgkin Lymphomas Identifies a Prognostic Signature for Mantle Cell Lymphoma

Rashmi S. Goswami, BSc, MD, FRCPC, Levi Waldron, Ph.D., Patricia P Reis, Ph.D., Yali Xuan, Wei Xu, Ph.D., John Kuruvilla, David Good, MD, Denis Bailey, MD, Alanna Church, MD, Tara Baetz, MD, David LeBrun, MD, Raymond Lai, MD, Ph.D., Laurie Sehn, MD, MPH, Pedro Farinha, MD, Randy D. Gascoyne, MD, Michael Crump, MD, FRCPC, Igor Jurisica, Ph.D., Suzanne Kamel-Reid, Ph.D.

Blood (2010) 116 (21): 800.

https://doi.org/10.1182/blood.V116.21.800.800

Published: 2010

Journal Articles

Southwest Oncology Group Study S0530: A Phase 2 Trial of Clofarabine/ Cytarabine for Relapsed/ Refractory Acute Lymphocytic Leukemia.

Anjali Advani, MD, Holly Gundacker, MS, Olga Sala-Torra, MD, Jerald Radich, MD, Raymond Lai, MD, PhD, Marilyn L. Slovak, PhD, Jeffrey E Lancet, MD, Steve Coutre, MD, Robert K Stuart, MD, Martha P. Mims, MD, PhD, Patrick Stiff, MD, Frederick R. Appelbaum, MD

Blood (2009) 114 (22): 3094.

https://doi.org/10.1182/blood.V114.22.3094.3094

Published: 2009

Journal Articles

High Oct-2 Protein Expression Is Associated with Decreased Overall Survival, While High Bob-1 Protein Expression Is Associated with Improved Overall Survival in Myeloma Patients.

Inka Toman, M.Sc., Jonathan Loree, Alex Klimowicz, Ph.D., Nizar J Bahlis, MD, Raymond Lai, MD, PhD, Andrew Belch, MD, Linda M. Pilarski, PhD, Tony Reiman, MD

Blood (2009) 114 (22): 2822.

https://doi.org/10.1182/blood.V114.22.2822.2822

Published: 2009

Journal Articles

IGF-IR tyrosine kinase interacts with NPM-ALK oncogene to induce survival of T-cell ALK + anaplastic large-cell lymphoma cells

Ping Shi, Raymond Lai, Quan Lin, Abid S. Iqbal, Leah C. Young, Larry W. Kwak, Richard J. Ford, Hesham M. Amin

Blood (2009) 114 (2): 360–370.

https://doi.org/10.1182/blood-2007-11-125658

Published: 2009

Includes: Supplemental data

Journal Articles

Transformation of follicular lymphoma to diffuse large B-cell lymphoma may occur by divergent evolution from a common progenitor cell or by direct evolution from the follicular lymphoma clone

Emanuela Carlotti, David Wrench, Janet Matthews, Sameena Iqbal, Andrew Davies, Andrew Norton, Jason Hart, Raymond Lai, Silvia Montoto, John G. Gribben, T. Andrew Lister, Jude Fitzgibbon

Blood (2009) 113 (15): 3553–3557.

https://doi.org/10.1182/blood-2008-08-174839

Published: 2009

Includes: Supplemental data

Journal Articles

Constitutive activation of the Wnt canonical pathway in mantle cell lymphoma

Pascal Gelebart, Mona Anand, Hanan Armanious, Anthea C. Peters, Jennifer Dien Bard, Hesham M. Amin, Raymond Lai

Blood (2008) 112 (13): 5171–5179.

https://doi.org/10.1182/blood-2008-02-139212

Published: 2008

Journal Articles

Epigenetic Regulation of the WNT Canonical Pathway in Mantle Cell Lymphoma.

Anthea C Peters, MD, MSc, Randy Chung, MD, Charles S Wong, Leah C Young, PhD, Tony Reiman, MD, Raymond Lai, MD, PhD

Blood (2008) 112 (11): 3340.

https://doi.org/10.1182/blood.V112.11.3340.3340

Published: 2008

Journal Articles

Biologic Prognostic Markers in Diffuse Large B-Cell Lymphoma Patients Treated with Dose Adjusted EPOCH-R: a CALGB 50103 Correlative Science Study

Eric D Hsi, MD, Jonathan Said, Jeffrey L Johnson, Sinho Jung, Raymond Lai, MD, Dan Jones, MD, PhD, Amy Chadburn, MD, Bruce D. Cheson, MD, Wyndham H. Wilson

Blood (2008) 112 (11): 476.

https://doi.org/10.1182/blood.V112.11.476.476

Published: 2008

Journal Articles

Determining the Mechanism of Transformation of Follicular Lymphoma into Diffuse Large B Cell Lymphoma.

Emanuela Carlotti, PhD, David Wrench, MD, Sameena Iqbal, BSc, Derville O’Shea, MD, Andrew Davies, MD, PhD, Priya Virappane, BSc, Jason Hart, MD, Raymond Lai, MD, PhD, John G. Gribben, MD, DSc, Andrew T. Lister, MD, Jude Fitzgibbon, PhD

Blood (2007) 110 (11): 181.

https://doi.org/10.1182/blood.V110.11.181.181

Published: 2007

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Nuclear NPM-ALK Protects Myc from Proteosomal Degradation and Contributes to High Protein Expression in Cancer Stem-like Cells in ALK-Positive Anaplastic Large Cell Lymphoma

The Application of the SORE6 Reporter in the Studies of Acute Myeloid Leukemia - a Novel Model for Disease Relapses

Epidemiology of Post-Transplant Lymphoproliferative Disorders in Children with Solid Organ Transplant over 34 Years of a Single Center Experience

The Identification of Novel Epigenetic Therapies for ALK-Driven Haematological Malignancies

FOXM1 and the NPM-ALK/STAT3 Axis Form a Novel Positive Feedback Loop in Promoting the Oncogenesis of ALK-Positive Anaplastic Large Cell Lymphoma

Monomorphic Post Transplant Lymphoproliferative Disorder (Diffuse Large B Cell Lymphoma subtype) Successfully Treated without Chemotherapy after Solid Organ Transplant in Children

CD3 T-Cell Infiltrates at Diagnosis Predicts Overall Survival in Solid Organ Transplant Recipients with Post-Transplant Lymphoproliferative Disorders (PTLD)

Morphologic Evolution in Post-Transplant Lymphoproliferative Disorders (PTLD): A Clinicopathologic Case Series

STAT1 is phosphorylated and downregulated by the oncogenic tyrosine kinase NPM-ALK in ALK-positive anaplastic large-cell lymphoma

A 7-Gene Microrna Signature Characteristic of Mantle Cell Lymphoma Reveals Focal Adhesion and Integrin Signalling, Proteasome-Mediated Degradation, and the PI3K Signalling Cascade As Important to MCL Pathogenesis

Constitutive activation of metalloproteinase ADAM10 in mantle cell lymphoma promotes cell growth and activates the TNFα/NFκB pathway

Comparing MicroRNA Expression In Aggressive and Indolent Non-Hodgkin Lymphomas Identifies a Prognostic Signature for Mantle Cell Lymphoma

Southwest Oncology Group Study S0530: A Phase 2 Trial of Clofarabine/ Cytarabine for Relapsed/ Refractory Acute Lymphocytic Leukemia.

High Oct-2 Protein Expression Is Associated with Decreased Overall Survival, While High Bob-1 Protein Expression Is Associated with Improved Overall Survival in Myeloma Patients.

IGF-IR tyrosine kinase interacts with NPM-ALK oncogene to induce survival of T-cell ALK + anaplastic large-cell lymphoma cells

Transformation of follicular lymphoma to diffuse large B-cell lymphoma may occur by divergent evolution from a common progenitor cell or by direct evolution from the follicular lymphoma clone

Constitutive activation of the Wnt canonical pathway in mantle cell lymphoma

Epigenetic Regulation of the WNT Canonical Pathway in Mantle Cell Lymphoma.

Biologic Prognostic Markers in Diffuse Large B-Cell Lymphoma Patients Treated with Dose Adjusted EPOCH-R: a CALGB 50103 Correlative Science Study

Determining the Mechanism of Transformation of Follicular Lymphoma into Diffuse Large B Cell Lymphoma.

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