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Journal Articles

Preliminary Results of a Phase 1 Dose Escalation Study of the First-in-Class IgM Based Bispecific Antibody Igm-2323 (anti-CD20 x anti-CD3) in Patients with Advanced B-Cell Malignancies

Elizabeth Budde, MDPhD, Ajay K. Gopal, MD, Ian W. Flinn, MD PhD, Loretta J. Nastoupil, MD, Michael S. Gordon, MD, Ching-Fai Pang, PhD, Bruce Keyt, PhD, Steve Carroll, PhD, Maya Leabman, PhD, Genevive Hernandez, PhD, Iris Sison, Daniel Chen, MD PhD, Wayne Godfrey, MD, Philippe Armand, MD PhD

Blood (2020) 136 (Supplement 1): 45–46.

https://doi.org/10.1182/blood-2020-134983

Published: 2020

Journal Articles

Phase 1 Trial of Cobomarsen, an Inhibitor of Mir-155, in Cutaneous T Cell Lymphoma

Blood (2018) 132 (Supplement 1): 2903.

https://doi.org/10.1182/blood-2018-99-119861

Published: 2018

Journal Articles

Phase 1b Evaluation of the Safety and Efficacy of a 30-Minute IV Infusion of Carfilzomib In Patients with Relapsed and/or Refractory Multiple Myeloma

Kyriakos Papadopoulos, MD, David Samuel diCapua Siegel, MD, PhD, Seema B. Singhal, MD, Jeffrey R. Infante, MD, Edward A. Sausville, MD, PhD, Michael S. Gordon, MD, Michael Kauffman, MD, PhD, Tina Woo, Susan Lee, Lynne Bui, MD, Alison L. Hannah, MD, Peter Lee, MD, PhD

Blood (2010) 116 (21): 3024.

https://doi.org/10.1182/blood.V116.21.3024.3024

Published: 2010

Journal Articles

Results from the Phase I Portion of a Phase I/II Study of ATN-224 and Bortezomib for Patients with Multiple Myeloma Relapsed from or Refractory to Bortezomib

James R. Berenson, MD, Thomas Ervin, MD, Ralph V. Boccia, MD, Olcay Batuman, MD, Regina Swift, RN, Christina DiLauro Abaya, BA, Andrew P. Mazar, PhD, Gilad S. Gordon, MD, Steven D. Reich, MD, Jennifer A. Callahan, BA

Blood (2008) 112 (11): 5185.

https://doi.org/10.1182/blood.V112.11.5185.5185

Published: 2008

Journal Articles

Pleiotrophin is highly expressed by myeloma cells and promotes myeloma tumor growth

Haiming Chen, Melinda S. Gordon, Richard A. Campbell, Mingjie Li, Cathy S. Wang, Hee Jin Lee, Eric Sanchez, Steven J. Manyak, Dorina Gui, Dror Shalitin, Jonathan Said, Yunchao Chang, Thomas F. Deuel, Stavroula Baritaki, Benjamin Bonavida, James R. Berenson

Blood (2007) 110 (1): 287–295.

https://doi.org/10.1182/blood-2006-08-042374

Published: 2007

Journal Articles

Arsenic Trioxide Affects Early Stage Angiogenesis through Inhibition of CD14 Monocyte Transdifferentiation into Endothelial Cells Induced by Pleiotrophin and mCSF.

Haiming Chen, MD, PhD, Mingjie Li, Richard A. Campbell, Melinda S. Gordon, PhD, Dror Shalitin, PhD, Cathy S. Wang, Ariana M. Berenson, Jennifer Li, Hetty Wong, James Wang, Benjamin Bonavida, PhD, James R. Berenson, MD

Blood (2006) 108 (11): 1267.

https://doi.org/10.1182/blood.V108.11.1267.1267

Published: 2006

Journal Articles

Pleiotrophin Is Highly Produced by Myeloma and Breast Cancer and Transdifferentiates Human Monocytes into Endothelial Cells That Are Incorporated into Tumoral Blood Vessels.

Haiming Chen, MD, PhD, Richard A. Campbell, Mingjie Li, Melinda S. Gordon, PhD, Dror Shalitin, PhD, Cathy S. Wang, Ariana M. Berenson, Jennifer Li, Hetty Wong, Benjamin Bonavida, PhD, James R. Berenson, MD

Blood (2006) 108 (11): 1269.

https://doi.org/10.1182/blood.V108.11.1269.1269

Published: 2006

Journal Articles

PK11195, a Ligand of the Peripheral Benzodiazepine Receptor, Inhibits Myeloma Cell Growth In Vitro and Chemosensitizes Myeloma Cells In Vivo in SCID-hu Models of Human Multiple Myeloma.

Richard A. Campbell, Eric Sanchez, Haiming Chen, MD, PhD, Lauren Turker, Olivia Trac, Mingjie Li, Dror Shalitin, PhD, Melinda S. Gordon, PhD, Shen Pang, PhD, Benjamin Bonavida, PhD, Jonathan Said, MD, Ronald J. Berenson, MD, James R. Berenson, MD

Blood (2006) 108 (11): 3459.

https://doi.org/10.1182/blood.V108.11.3459.3459

Published: 2006

Journal Articles

ZIO-101, a Novel Organic Arsenic, Inhibits Human Myeloma Cell Growth in a SCID-hu Model.

Richard A. Campbell, Eric Sanchez, Haiming Chen, MD, PhD, Lauren Turker, Mingjie Li, Olivia Trac, Dror Shalitin, Melinda S. Gordon, PhD, Shen Pang, PhD, Benjamin Bonavida, PhD, Jonathan Said, MD, Barbara Wallner, PhD, Robert P. Gale, MD, PhD, James R. Berenson, MD

Blood (2006) 108 (11): 3462.

https://doi.org/10.1182/blood.V108.11.3462.3462

Published: 2006

Journal Articles

Blocking TRAF6 Function Domain by TRAF6 Dominant Negative (TRAF6dn) for Inhibition of Multiple Myeloma Cell Proliferative and Increase of Apoptosis through Regulation of NF-κB and JNK Pathways.

Haiming Chen, MD, PhD, Mingjie Li, Richard A. Campbell, Melinda S. Gordon, PhD, Dror Shalitin, Cathy S. Wang, Ariana M. Berenson, Jennifer Li, Charles B. Drucker, Benjamin Bonavida, PhD, James R. Berenson, MD

Blood (2006) 108 (11): 3434.

https://doi.org/10.1182/blood.V108.11.3434.3434

Published: 2006

Journal Articles

Effects of a Novel Histone Deacetylase Inhibitor, PXD101, When Used as Monotherapy or in Combination with Bortezomib on Tumor Growth in Mouse Models of Human Multiple Myeloma.

Blood (2006) 108 (11): 3483.

https://doi.org/10.1182/blood.V108.11.3483.3483

Published: 2006

Journal Articles

Pleiotrophin Promotes Myeloma Proliferation through the Activation of Known and Novel Receptors.

Melinda S. Gordon, PhD, Hee Jin Lee, Richard A. Campbell, Charles B. Drucker, Matthew Katz, Richard K. Leuchter, Benjamin Bonavida, Ph.D., James R. Berenson, M.D.

Blood (2006) 108 (11): 4354.

https://doi.org/10.1182/blood.V108.11.4354.4354

Published: 2006

Journal Articles

The Humanized Anti-CD40 Antibody SGN-40 Inhibits Tumor Growth in LAGκ-1A, a CD40 + Mouse Model of Human Multiple Myeloma.

Richard A. Campbell, Melinda S. Gordon, PhD, Eric Sanchez, Haiming Chen, MD, PhD, Lauren Turker, Olivia Trac, Mingjie Li, Shen Pang, PhD, Benjamin Bonavida, PhD, Jonathan Said, MD, Jonathan G. Drachman, MD, James R. Berenson, MD

Blood (2006) 108 (11): 3506.

https://doi.org/10.1182/blood.V108.11.3506.3506

Published: 2006

Journal Articles

Anti-VEGF Antibody Treatment Markedly Inhibits Tumor Growth in SCID-hu Models of Human Multiple Myeloma.

Blood (2006) 108 (11): 846.

https://doi.org/10.1182/blood.V108.11.846.846

Published: 2006

Journal Articles

Circulating Tie2-Expressing Cells Are Increased in Multiple Myeloma Patients, Correlate with Serum Pleiotrophin Levels and May Develop from This Myeloma Angiogenic and Growth Factor.

Haiming Chen, MD, PhD, Richard A. Campbell, Melinda S. Gordon, PhD, Steven J. Manyak, Cathy Wang, Mingjie Li, Hee Jin Lee, Jennifer Wei, Howard S. Yeh, MD, Benjamin Bonavida, PhD, James R. Berenson, MD

Blood (2005) 106 (11): 2494.

https://doi.org/10.1182/blood.V106.11.2494.2494

Published: 2005

Journal Articles

Identification of Novel Receptors on Myeloma Cells and Monocytes That Contribute to Myeloma Tumor Proliferation and Angiogenesis.

Melinda S. Gordon, PhD, Hee Jin Lee, BS, Richard A. Campbell, BS, Haiming Chen, MD, Ph.D, Benjamin Bonavida, PhD, James R. Berenson, MD

Blood (2005) 106 (11): 2507.

https://doi.org/10.1182/blood.V106.11.2507.2507

Published: 2005

Journal Articles

Overexpression and Preferential Nuclear Translocation of the Transcription Factor Yin Yang 1 (YY1) in Human Bone Marrow-Derived Multiple Myeloma.

Sara Huerta-Yepez, PhD, Stravoula Baritaki, PhD, Angeles Hernandez-Cuecto, MD, Yu-Mei Anguino-Hernandez, Mehran Neshat, PhD, Haiming Chen, MD, Richard A. Campbell, Melinda S. Gordon, PhD, James R. Berenson, PhD, Benjamin Bonavida, PhD

Blood (2005) 106 (11): 3394.

https://doi.org/10.1182/blood.V106.11.3394.3394

Published: 2005

Journal Articles

Serum Pleiotrophin Is a New Multiple Myeloma Tumor Marker That Also Predicts Clinical Status.

Howard S. Yeh, MD, Haiming Chen, MD, PhD, Steven J. Manyak, Regina A. Swift, RN, Richard A. Campbell, Cathy Wang, Mingjie Li, Hee Jin, Lee, Melinda S. Gordon, PhD, Benjamin Bonavida, PhD, James R. Berenson, MD

Blood (2005) 106 (11): 3417.

https://doi.org/10.1182/blood.V106.11.3417.3417

Published: 2005

Journal Articles

Transdifferentiation of Monocytes into Endothelial Cells by Pleiotrophin.

Haiming Chen, MD, PhD, Richard A. Campbell, Cathy Wang, Mingjie Li, Hee Jin Lee, Howard S. Yeh, MD, Dorina Gui, MD, PhD, Melinda S. Gordon, PhD, Jonathan Said, MD, Benjamin Bonavida, PhD, James R. Berenson, MD

Blood (2005) 106 (11): 391.

https://doi.org/10.1182/blood.V106.11.391.391

Published: 2005

Journal Articles

Differential Presence of Truncated Forms of Transcription Factor Yin Yang 1 (YY1) in Bone Marrow of Multiple Myeloma Patients.

Mehran S. Neshat, PhD, Haiming Chen, MD, PhD, Melinda S. Gordon, PhD, James R. Berenson, MD, Benjamin Bonavida, PhD

Blood (2005) 106 (11): 5083.

https://doi.org/10.1182/blood.V106.11.5083.5083

Published: 2005

NARROW

Preliminary Results of a Phase 1 Dose Escalation Study of the First-in-Class IgM Based Bispecific Antibody Igm-2323 (anti-CD20 x anti-CD3) in Patients with Advanced B-Cell Malignancies

Phase 1 Trial of Cobomarsen, an Inhibitor of Mir-155, in Cutaneous T Cell Lymphoma

Phase 1b Evaluation of the Safety and Efficacy of a 30-Minute IV Infusion of Carfilzomib In Patients with Relapsed and/or Refractory Multiple Myeloma

Results from the Phase I Portion of a Phase I/II Study of ATN-224 and Bortezomib for Patients with Multiple Myeloma Relapsed from or Refractory to Bortezomib

Pleiotrophin is highly expressed by myeloma cells and promotes myeloma tumor growth

Arsenic Trioxide Affects Early Stage Angiogenesis through Inhibition of CD14 Monocyte Transdifferentiation into Endothelial Cells Induced by Pleiotrophin and mCSF.

Pleiotrophin Is Highly Produced by Myeloma and Breast Cancer and Transdifferentiates Human Monocytes into Endothelial Cells That Are Incorporated into Tumoral Blood Vessels.

PK11195, a Ligand of the Peripheral Benzodiazepine Receptor, Inhibits Myeloma Cell Growth In Vitro and Chemosensitizes Myeloma Cells In Vivo in SCID-hu Models of Human Multiple Myeloma.

ZIO-101, a Novel Organic Arsenic, Inhibits Human Myeloma Cell Growth in a SCID-hu Model.

Blocking TRAF6 Function Domain by TRAF6 Dominant Negative (TRAF6dn) for Inhibition of Multiple Myeloma Cell Proliferative and Increase of Apoptosis through Regulation of NF-κB and JNK Pathways.

Effects of a Novel Histone Deacetylase Inhibitor, PXD101, When Used as Monotherapy or in Combination with Bortezomib on Tumor Growth in Mouse Models of Human Multiple Myeloma.

Pleiotrophin Promotes Myeloma Proliferation through the Activation of Known and Novel Receptors.

The Humanized Anti-CD40 Antibody SGN-40 Inhibits Tumor Growth in LAGκ-1A, a CD40 + Mouse Model of Human Multiple Myeloma.

Anti-VEGF Antibody Treatment Markedly Inhibits Tumor Growth in SCID-hu Models of Human Multiple Myeloma.

Circulating Tie2-Expressing Cells Are Increased in Multiple Myeloma Patients, Correlate with Serum Pleiotrophin Levels and May Develop from This Myeloma Angiogenic and Growth Factor.

Identification of Novel Receptors on Myeloma Cells and Monocytes That Contribute to Myeloma Tumor Proliferation and Angiogenesis.

Overexpression and Preferential Nuclear Translocation of the Transcription Factor Yin Yang 1 (YY1) in Human Bone Marrow-Derived Multiple Myeloma.

Serum Pleiotrophin Is a New Multiple Myeloma Tumor Marker That Also Predicts Clinical Status.

Transdifferentiation of Monocytes into Endothelial Cells by Pleiotrophin.

Differential Presence of Truncated Forms of Transcription Factor Yin Yang 1 (YY1) in Bone Marrow of Multiple Myeloma Patients.

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American Society of Hematology

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American Society of Hematology

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