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Sarah C Nabinger
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Journal Articles

Gain of Function Mutant p53 Drives Clonal Hematopoiesis and the Pathogenesis of Myelodysplastic Syndromes

Sisi Chen, Hao Yu, PhD, Rui Gao, PhD, Sarah C. Nabinger, PhD, Michihiro Kobayashi, MD PhD, Chonghua Yao, Linsey Mayo, PhD, Reuben Kapur, PhD, Mervin C. Yoder, MD, Hal E. Broxmeyer, PhD, Zhonghua Gao, Yan Liu, PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 2489.
https://doi.org/10.1182/blood.V130.Suppl_1.2489.2489
Published: 2017
Journal Articles

PRL2 Phosphatase Is a Key Mediator of Oncogenic Cytokine Signaling in Leukemia Stem Cells

Michihiro Kobayashi, MD PhD, Yunpeng Bai, PhD, Sisi Chen, BS, Sarah C Nabinger, PhD, Chonghua Yao, MD, Zhong-Yin Zhang, PhD, Yan Liu, PhD
Journal: Blood
Blood (2016) 128 (22): 724.
https://doi.org/10.1182/blood.V128.22.724.724
Published: 2016
Journal Articles

Mutant p53 Drives the Development of Pre-Leukemic Hematopoietic Stem Cells through Modulating Epigenetic Regulators

Sarah C Nabinger, PhD, Michihiro Kobayashi, MD PhD, Rui Gao, PhD, Sisi Chen, BS, Chonghua Yao, MD, Feng-Chun Yang, MD PhD, Yan Liu, PhD
Journal: Blood
Blood (2015) 126 (23): 307.
https://doi.org/10.1182/blood.V126.23.307.307
Published: 2015
Journal Articles

Macrophage NADPH Oxidase Activation and ROS Production Is Positively Regulated By Shp2 Phosphatase Function

XingJun Li, MD PhD, Charles Goodwin, BS, Zhenyun Yang, Sarah C Nabinger, PhD, Briana Richine, Gordon Chan, Helmut Hanenberg, Hiroaki Ohnishi, MD, Takashi Matozaki, MD PhD, Jamel El Benna, Gen-Sheng Feng, PhD, Benjamin Neel, MD PhD, Rebecca J. Chan, MD PhD
Journal: Blood
Blood (2014) 124 (21): 1397.
https://doi.org/10.1182/blood.V124.21.1397.1397
Published: 2014
Journal Articles

The Protein Tyrosine Phosphatase, Shp2, Positively Contributes to FLT3-ITD-Induced Malignant Disease in Vivo and Co-Localizes with Nuclear Phospho-STAT5 in FLT3-ITD-Expressing Leukemic Cells.

Sarah C Nabinger, PhD, Xing Jun Li, MD, PhD, Baskar Ramdas, Ph.D., Yantao He, PhD, Xian Zhang, Ph.D., Briana Richine, Joshua Bowling, Seiji Fukuda, MD, PhD, Shreevrat Goenka, Ph.D., Ziyue Liu, Ph.D., Gen-Sheng Feng, PhD, Menggang Yu, Ph.D., George Sandusky, MD, H. Scott Boswell, MD, Zhong-Yin Zhang, PhD, Reuben Kapur, PhD, Rebecca J. Chan, MD, PhD
Journal: Blood
Blood (2012) 120 (21): 2420.
https://doi.org/10.1182/blood.V120.21.2420.2420
Published: 2012
Journal Articles

Unraveling a Novel Mechanism of Stat5 Regulation by FAK and Rac1 in Flt3ITD Induced Leukemogenesis

Anindya Chatterjee, MS, PhD, Joydeep Ghosh, Baskar Ramdas, Ph.D., Sasidhar Vemula, PhD, Holly Martin, Raghuveer Mali, Ph.D., Sarah C Nabinger, PhD, Charles B Goodwin, H. Scott Boswell, MD, Rebecca J. Chan, MD, PhD, Reuben Kapur, PhD
Journal: Blood
Blood (2012) 120 (21): 858.
https://doi.org/10.1182/blood.V120.21.858.858
Published: 2012
Journal Articles

KIT Induced Myeloproliferative Disease Is Dependent on PI3Kinase and SHP2 Phosphatase: Identification of SHP2 As a Druggable Target for Treating MPD and AML

Peilin Ma, MD, PhD, Raghuveer Mali, Ph.D., Li-Fan Zeng, PhD, Holly Martin, Baskar Ramdas, Ph.D., Yantao He, PhD, Emily Sims, Joydeep Ghosh, Ph.D, Sarah C Nabinger, Shuo Li, Veerendra Munugalavadla, PhD, Anindya Chatterjee, PhD, George Sandusky, MD, Andrew Craig, PhD, Kevin D. Bunting, PhD, Gen-Sheng Feng, Rebecca J. Chan, MD, PhD, Zhong-Yin Zhang, PhD, Reuben Kapur, PhD
Journal: Blood
Blood (2011) 118 (21): 868.
https://doi.org/10.1182/blood.V118.21.868.868
Published: 2011
Journal Articles

Targeting the Protein Phosphatase, Shp2, Reduces FLT3-ITD-Induced Hyperproliferation of Murine Hematopoietic Progenitors.

Sarah C Nabinger, Yantao He, Fuqin Yin, Xian Zhang, Linda Senbanjo, Seiji Fukuda, MD, PhD, Menggang Yu, Gen-Sheng Feng, Zhong-Yin Zhang, Reuben Kapur, PhD, Rebecca J. Chan, MD, PhD
Journal: Blood
Blood (2009) 114 (22): 827.
https://doi.org/10.1182/blood.V114.22.827.827
Published: 2009
Journal Articles

The Role of Protein Tyrosine Phosphatase, Shp2, in FLT3-ITD-Induced Leukemogenesis.

Sarah C Nabinger, Seiji Fukuda, M.D., Reuben Kapur, PhD, Rebecca Chan, MD, PhD
Journal: Blood
Blood (2008) 112 (11): 1804.
https://doi.org/10.1182/blood.V112.11.1804.1804
Published: 2008
Journal Articles

Increased C-Jun and Reduced GATA2 Expression Promotes Aberrant Monocytic Differentiation and Expansion Induced by Activating PTPN11 Mutants

Zhenyun Yang, Takako Kondo, Ph.D., Cara s Voorhorst, MS, Sarah C Nabinger, Leila Ndong, Fuqin Yin, Edward m Chan, M.D., Oliver Wurstlin, Christian Kratz, Charlotte Marie Niemeyer, MD, Christian Flotho, MD, Eri Hashino, Rebecca Chan, MD, PhD
Journal: Blood
Blood (2008) 112 (11): 3720.
https://doi.org/10.1182/blood.V112.11.3720.3720
Published: 2008