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Sonali P. Barwe
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Journal Articles

Azacitidine and Panobinostat Overcome Bone Marrow Microenvironment-Induced Chemoprotection in KMT2A- rearranged Pediatric AML

Kara Lehner, Anilkumar Gopalakrishnapillai, E. Anders Kolb, Sonali P. Barwe
Journal: Blood
Blood (2022) 140 (Supplement 1): 5963–5964.
https://doi.org/10.1182/blood-2022-171114
Published: 2022
Journal Articles

Preclinical Validation of EZH2 and HDAC I Dual Inhibition As a Potent Therapy for Refractory Myeloid Leukemia Associated with Down Syndrome

Kader Cicek, Joshua R. Faust, Meredith Tavenner, E. Anders Kolb, Sonali P. Barwe, Anilkumar Gopalakrishnapillai
Journal: Blood
Blood (2022) 140 (Supplement 1): 5951–5952.
https://doi.org/10.1182/blood-2022-170549
Published: 2022
Journal Articles

A Bone Marrow Mimetic 3D Co-Culture Model for Ex Vivo drug Testing of Down Syndrome-Myeloid Leukemia Cells

Ishnoor Sidhu, Sonali P. Barwe, Kristi Lynn Kiick, E. Anders Kolb, Anilkumar Gopalakrishnapillai
Journal: Blood
Blood (2022) 140 (Supplement 1): 8805–8806.
https://doi.org/10.1182/blood-2022-170637
Published: 2022
Journal Articles

Selinexor Prolongs Survival in Patient-Derived Xenograft Models of Down Syndrome Myeloid Leukemia

Sonali P. Barwe, Yana Pikman, E. Anders Kolb, Anilkumar Gopalakrishnapillai
Journal: Blood
Blood (2022) 140 (Supplement 1): 8817–8818.
https://doi.org/10.1182/blood-2022-170441
Published: 2022
Journal Articles

The menin-MLL1 interaction is a molecular dependency in NUP98 -rearranged AML

Emily B. Heikamp, Jill A. Henrich, Florian Perner, Eric M. Wong, Charles Hatton, Yanhe Wen, Sonali P. Barwe, Anilkumar Gopalakrishnapillai, Haiming Xu, Hannah J. Uckelmann, Sumiko Takao, Yaniv Kazansky, Yana Pikman, Gerard M. McGeehan, Edward A. Kolb, Alex Kentsis, Scott A. Armstrong
Journal: Blood
Blood (2022) 139 (6): 894–906.
https://doi.org/10.1182/blood.2021012806
Published: 2022
Includes: Supplemental data
Journal Articles

Bcl2 Inhibitor and DNA Hypomethylating Agent Prolong Survival in Patient-Derived Xenograft Model of Down Syndrome Myeloid Leukemia By Synergistic Downregulation of Cytokine Signaling

Sonali P. Barwe, Erin Lynn Crowgey, Qinzhuo Zhang, E. Anders Kolb, Anilkumar Gopalakrishnapillai
Journal: Blood
Blood (2021) 138 (Supplement 1): 3452.
https://doi.org/10.1182/blood-2021-154391
Published: 2021
Journal Articles

Epigenetic Drug Combination Alters Methylation Patterns in Patient-Derived Xenograft Models of KMT2A -Rearranged Pediatric AML Treated In Vivo

Anilkumar Gopalakrishnapillai, Erin Lynn Crowgey, Adam Marsh, E. Anders Kolb, Sonali P. Barwe
Journal: Blood
Blood (2021) 138 (Supplement 1): 2376.
https://doi.org/10.1182/blood-2021-154456
Published: 2021
Journal Articles

T Cell Engaging Bispecific Antibodies Produce Durable Response in Mesothelin-Positive Patient-Derived Xenograft Models of Pediatric AML

Anilkumar Gopalakrishnapillai, Colin Correnti, Kristina Pilat, Ida Lin, Albe Man Kid Chan, Ashok D. Bandaranayake, Christopher Mehlin, Anne Kisielewski, Darcy Hamill, Allison Kaeding, Soheil Meshinchi, James Olson, E. Anders Kolb, Sonali P. Barwe
Journal: Blood
Blood (2021) 138 (Supplement 1): 1280.
https://doi.org/10.1182/blood-2021-151907
Published: 2021
Journal Articles

Imetelstat Significantly Reduces Leukemia Stem Cells in Patient-Derived Xenograft Models of Pediatric AML

Sonali P. Barwe, Fei Huang, E. Anders Kolb, Anilkumar Gopalakrishnapillai
Journal: Blood
Blood (2021) 138 (Supplement 1): 3352.
https://doi.org/10.1182/blood-2021-151607
Published: 2021
Journal Articles

Hydrogel-Based 3D Culture Model for Down Syndrome Associated Transient Myeloproliferative Disorder Using Customized Induced Pluripotent Stem Cells

Ishnoor Sidhu, Sonali P. Barwe, Kristi Lynn Kiick, E. Anders Kolb, Anilkumar Gopalakrishnapillai
Journal: Blood
Blood (2021) 138 (Supplement 1): 1137.
https://doi.org/10.1182/blood-2021-151274
Published: 2021
Journal Articles

Introduction of STAG2 Mutation in an iPSC Model of Transient Abnormal Myelopoiesis Mimics Down Syndrome Myeloid Leukemia

Ishnoor Sidhu, Sonali P. Barwe, E. Anders Kolb, Anilkumar Gopalakrishnapillai
Journal: Blood
Blood (2021) 138 (Supplement 1): 1138.
https://doi.org/10.1182/blood-2021-151875
Published: 2021
Journal Articles

Evaluating the Efficacy of PRMT5 Inhibitor C220 in Patient-Derived Xenograft Models of Pediatric Acute Myeloid Leukemia

Anilkumar Gopalakrishnapillai, Anne Kisielewski, Yang Zhang, Bruce Ruggeri, Peggy Scherle, E. Anders Kolb, Sonali P. Barwe
Journal: Blood
Blood (2021) 138 (Supplement 1): 1170.
https://doi.org/10.1182/blood-2021-151671
Published: 2021
Journal Articles

Combination Of Inhibitors Against DNA Methyltransferases and Histone Deacetylases Synergistically Suppresses Cell Viability In Acute Myeloid Cells In a p53-Dependent Manner

Anilkumar Gopalakrishnapillai, PhD, Sonali P Barwe, PhD, E. Anders Kolb, MD
Journal: Blood
Blood (2013) 122 (21): 4894.
https://doi.org/10.1182/blood.V122.21.4894.4894
Published: 2013