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Journal Articles

Incidence and Implications of Skin Cancers in Cancercare Manitoba Chronic Lymphocytic Leukemia (CLL) Clinic Patients

Sara Beiggi, PhD, Mohammad Pannu, Versha Banerji, MD FRCP, Dhali H.S. Dhaliwal, MD FRCP, Spencer B. Gibson, PhD, Marni Wiseman, MD FRCP, James B. Johnston, MD FRCP

Blood (2016) 128 (22): 4359.

https://doi.org/10.1182/blood.V128.22.4359.4359

Published: 2016

Journal Articles

High Cumulative Illness Rating Scale (CIRS) Score in CLL Correlates with Short CLL Telomere Length and Decreased Survival

Lin Yang, Sara Beiggi, PhD, Yunli Zhang, Sara Kost, Robert Schmidt, BSc, Gangimeg Ishdorj, Dhali H.S. Dhaliwal, MD FRCP, Versha Banerji, MD FRCP, Sabine Mai, PhD, Spencer B. Gibson, PhD, James B. Johnston, MD FRCP

Blood (2016) 128 (22): 4362.

https://doi.org/10.1182/blood.V128.22.4362.4362

Published: 2016

Journal Articles

An Phase 2 Study of Lenalidomide in Combination with Oral Dexamethasone in Previously Untreated, Symptomatic Patients with Chronic Lymphocytic Leukemia (CLL)

Christine I Chen, MD, Harminder Paul, Susi Snitzler, RN, Lisa W Le, MSc, Ellen Nong Wei, Anthea Lau, James B Johnston, MD, Spencer B. Gibson, PhD, Michelle L. Queau, B.Sc, Suzanne Trudel, MD

Blood (2015) 126 (23): 4163.

https://doi.org/10.1182/blood.V126.23.4163.4163

Published: 2015

Journal Articles

Lysosome Membrane Permeabilization Causes Cell Death in Primary Chronic Lymphocytic Leukemia Cells

Rebecca Dielschneider, BSc, Hannah Eisenstat, James B. Johnston, MD, Spencer B Gibson, PhD

Blood (2014) 124 (21): 930.

https://doi.org/10.1182/blood.V124.21.930.930

Published: 2014

Journal Articles

Clinical Impact of Telomere Shortening in Normal and Leukemia Cells in Chronic Lymphocytic Leukemia

Lin Yang, MD PhD, Sara Beiggi, PhD, Yunli Zhang, Robert Schmidt, Spencer B Gibson, PhD, James B. Johnston, MD

Blood (2014) 124 (21): 5641.

https://doi.org/10.1182/blood.V124.21.5641.5641

Published: 2014

Journal Articles

The Valproic Acid-Fludarabine Combination Induces a Synergistic Response in Chronic Lymphocytic Leukemia Via a Mechanism Involving the Lysosomal Protease Cathepsin B.

Ju-Yoon Yoon, David Szwajcer, MD, FRCPC, Ganchimeg Ishdorj, PhD, Pat Benjaminson, RN, CON(C), James B Johnston, MD, Spencer B Gibson, PhD

Blood (2012) 120 (21): 2892.

https://doi.org/10.1182/blood.V120.21.2892.2892

Published: 2012

Journal Articles

An Open-Label Phase 2 Study of Lenalidomide in Combination with Oral Dexamethasone in the Previously Untreated, Symptomatic Patients with Chronic Lymphocytic Leukemia (CLL).

Christine Chen, MD, Harminder Paul, Luisa Del Rizzo, Lisa W Le, MSc, Ellen Nong Wei, Anthea Lau, James B Johnston, MD, Spencer B Gibson, PhD, Michelle Brown, Suzanne Trudel, MD

Blood (2012) 120 (21): 2895.

https://doi.org/10.1182/blood.V120.21.2895.2895

Published: 2012

Journal Articles

Functional and Familial Risk of B Lineage Malignancies in Patients Carrying Single Nucleotide Polymorphisms (SNPs) in the Hyaluronan Synthase 1 Gene (HAS1),

Linda M. Pilarski, PhD, Hemalatha Kuppusamy, Jitra Kriangkum, PhD, Amanda Warkentin, Sunita Ghosh, PhD, Spencer B Gibson, PhD, Hlif Steingrimsdottir, MD, Vilhelmina Haraldsdottir, MD, James B Johnston, MD, FRCPC, Helga M Ogmundsdottir, MD, PhD, Andrew R Belch, MD

Blood (2011) 118 (21): 3930.

https://doi.org/10.1182/blood.V118.21.3930.3930

Published: 2011

Journal Articles

Effect of Valproic Acid (VPA) on Fludarabine Activity In Chronic Lymphocytic Leukemia (CLL) Patients

Ju-Yoon Yoon, MSc, HonBSc, David Szwajcer, MD, FRCP(C), Ganchimeg Ishdorj, PhD, Pat Benjaminson, RN, CON(C), Spencer B Gibson, PhD, James B Johnston, MD, FRCPC

Blood (2010) 116 (21): 4626.

https://doi.org/10.1182/blood.V116.21.4626.4626

Published: 2010

Journal Articles

TAPP2 links phosphoinositide 3-kinase signaling to B-cell adhesion through interaction with the cytoskeletal protein utrophin: expression of a novel cell adhesion-promoting complex in B-cell leukemia

Jennifer L. Costantini, Samuel M. S. Cheung, Sen Hou, Hongzhao Li, Sam K. Kung, James B. Johnston, John A. Wilkins, Spencer B. Gibson, Aaron J. Marshall

Blood (2009) 114 (21): 4703–4712.

https://doi.org/10.1182/blood-2009-03-213058

Published: 2009

Includes: Supplemental data

Journal Articles

Younger Patients with CLL/SLL Are Less Frequent and Have Favorable Survival in a Canadian Population Based Study: The Manitoba Cohort.

Versha Banerji, MD, FRCPC, Alain Demers, PhD, James B. Johnston, MD FRCPC, Marshall W. Pitz, MD FRCPC, Zoanne Nugent, PhD, Carmen Morales, MD, Salah Mahmud, MD MS, Donna Hewitt, RN, Spencer B. Gibson, PhD, Matthew D. Seftel, MD FRCPC

Blood (2006) 108 (11): 3335.

https://doi.org/10.1182/blood.V108.11.3335.3335

Published: 2006

Journal Articles

The Vascular Endothelial Growth Factor (VEGF) Autocrine Survival Signaling Pathway in Chronic Lymphocytic Leukemia (CLL) Is Regulated by Lysophosphatidic Acid (LPA).

Xiaojie Hu, MSC, Jinmie Sun, Ph.D., James B. Johnston, M.B., Spencer B. Gibson, PhD

Blood (2006) 108 (11): 2810.

https://doi.org/10.1182/blood.V108.11.2810.2810

Published: 2006

Journal Articles

The Induction of Apoptosis by Histone Deacetylase Inhibition in Chronic Lymphocytic Leukemia (CLL) Cells Is Mediated through the TNF-Related Apoptosis-Inducing Ligand (TRAIL) Pathway.

David Szwajcer, MD, Spencer B. Gibson, PhD, James B. Johnston, MD

Blood (2005) 106 (11): 2982.

https://doi.org/10.1182/blood.V106.11.2982.2982

Published: 2005

Journal Articles

The Role of Proteasome Inhibitors and the Trail Apoptotic Pathway in the Treatment of Chronic Lymphocytic Leukemia.

Kristin E. McCrea, BSc, Albert Kabore, Ph.D, James B. Johnston, MD, Spencer B. Gibson, Ph.D

Blood (2005) 106 (11): 5011.

https://doi.org/10.1182/blood.V106.11.5011.5011

Published: 2005

Journal Articles

The Role of Histone Acetylation and Death Receptor 5 (DR5) Expression in the Treatment of Chronic Lymphocytic Leukemia (CLL).

Bonnie A. Graham, BSc, Brenda Kuschak, M.Sc, James B. Johnston, MD, Spencer B. Gibson, Ph.D

Blood (2005) 106 (11): 5017.

https://doi.org/10.1182/blood.V106.11.5017.5017

Published: 2005

Journal Articles

Lysophosphatidic Acid (LPA) Protects Primary Chronic Lymphocytic Leukemia (CLL) Cells from Apoptosis: Role for LPA as a Survival Factor in CLL.

Spencer B. Gibson, Ph.D., Xiaojie Hu, M.S., Neil Haney, B.S., Albert F. Kabore, Ph.D., James B. Johnston, M.D.

Blood (2004) 104 (11): 4788.

https://doi.org/10.1182/blood.V104.11.4788.4788

Published: 2004

Journal Articles

Proteasome Inhibiters Up-Regulate TRAIL/Apo2L and Its Receptors Significantly Contributing to Proteasome Inhibitor-Induced Apoptosis in Primary Chronic Lymphocytic Leukemia (CLL) Cells.

Albert F. Kabore, Ph.D., Kristin McCrea, B.S., James B. Johnston, M.D., Spencer B. Gibson, Ph.D.

Blood (2004) 104 (11): 2810.

https://doi.org/10.1182/blood.V104.11.2810.2810

Published: 2004

NARROW

Incidence and Implications of Skin Cancers in Cancercare Manitoba Chronic Lymphocytic Leukemia (CLL) Clinic Patients

High Cumulative Illness Rating Scale (CIRS) Score in CLL Correlates with Short CLL Telomere Length and Decreased Survival

An Phase 2 Study of Lenalidomide in Combination with Oral Dexamethasone in Previously Untreated, Symptomatic Patients with Chronic Lymphocytic Leukemia (CLL)

Lysosome Membrane Permeabilization Causes Cell Death in Primary Chronic Lymphocytic Leukemia Cells

Clinical Impact of Telomere Shortening in Normal and Leukemia Cells in Chronic Lymphocytic Leukemia

The Valproic Acid-Fludarabine Combination Induces a Synergistic Response in Chronic Lymphocytic Leukemia Via a Mechanism Involving the Lysosomal Protease Cathepsin B.

An Open-Label Phase 2 Study of Lenalidomide in Combination with Oral Dexamethasone in the Previously Untreated, Symptomatic Patients with Chronic Lymphocytic Leukemia (CLL).

Functional and Familial Risk of B Lineage Malignancies in Patients Carrying Single Nucleotide Polymorphisms (SNPs) in the Hyaluronan Synthase 1 Gene (HAS1),

Effect of Valproic Acid (VPA) on Fludarabine Activity In Chronic Lymphocytic Leukemia (CLL) Patients

TAPP2 links phosphoinositide 3-kinase signaling to B-cell adhesion through interaction with the cytoskeletal protein utrophin: expression of a novel cell adhesion-promoting complex in B-cell leukemia

Younger Patients with CLL/SLL Are Less Frequent and Have Favorable Survival in a Canadian Population Based Study: The Manitoba Cohort.

The Vascular Endothelial Growth Factor (VEGF) Autocrine Survival Signaling Pathway in Chronic Lymphocytic Leukemia (CLL) Is Regulated by Lysophosphatidic Acid (LPA).

The Induction of Apoptosis by Histone Deacetylase Inhibition in Chronic Lymphocytic Leukemia (CLL) Cells Is Mediated through the TNF-Related Apoptosis-Inducing Ligand (TRAIL) Pathway.

The Role of Proteasome Inhibitors and the Trail Apoptotic Pathway in the Treatment of Chronic Lymphocytic Leukemia.

The Role of Histone Acetylation and Death Receptor 5 (DR5) Expression in the Treatment of Chronic Lymphocytic Leukemia (CLL).

Lysophosphatidic Acid (LPA) Protects Primary Chronic Lymphocytic Leukemia (CLL) Cells from Apoptosis: Role for LPA as a Survival Factor in CLL.

Proteasome Inhibiters Up-Regulate TRAIL/Apo2L and Its Receptors Significantly Contributing to Proteasome Inhibitor-Induced Apoptosis in Primary Chronic Lymphocytic Leukemia (CLL) Cells.

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American Society of Hematology

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American Society of Hematology

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