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Journal Articles

In Vivo Evidence That Ibrutininb Deregulates Chemokine Receptor CXCR4 Surface Membrane Expression and Signaling, Along with Inhibiting B Cell Antigen Receptor Signaling, As Causes for Defective Homing and Impaired Retention of CLL Cells in Tissues

Shih-Shih Chen, PhD, Betty Y. Chang, Stella Chang, Timothy Tong, Yong-Rui Zou, Barbara Sherry, PhD, Joseph J. Buggy, PhD, Jan A. Burger, MD PhD, Kanti R. Rai, MD, Nicholas Chiorazzi, MD
Journal: Blood
Blood (2014) 124 (21): 1948.
https://doi.org/10.1182/blood.V124.21.1948.1948
Published: 2014
Journal Articles

Ibrutinib inhibits BCR and NF-κB signaling and reduces tumor proliferation in tissue-resident cells of patients with CLL

Clinical Trials & Observations
Sarah E. M. Herman, Rashida Z. Mustafa, Jennifer A. Gyamfi, Stefania Pittaluga, Stella Chang, Betty Chang, Mohammed Farooqui, Adrian Wiestner
Journal: Blood
Blood (2014) 123 (21): 3286–3295.
https://doi.org/10.1182/blood-2014-02-548610
Published: 2014
Includes: Supplemental data
Journal Articles

Egress of CD19 + CD5 + cells into peripheral blood following treatment with the Bruton tyrosine kinase inhibitor ibrutinib in mantle cell lymphoma patients

Betty Y. Chang, Michelle Francesco, Martin F. M. De Rooij, Padmaja Magadala, Susanne M. Steggerda, Min Mei Huang, Annemieke Kuil, Sarah E. M. Herman, Stella Chang, Steven T. Pals, Wyndham Wilson, Adrian Wiestner, Marcel Spaargaren, Joseph J. Buggy, Laurence Elias
Journal: Blood
Blood (2013) 122 (14): 2412–2424.
https://doi.org/10.1182/blood-2013-02-482125
Published: 2013
Includes: Supplemental data
Journal Articles

Early Changes in Cytokines, Chemokines and Indices of Bone Metabolism in a Phase 2 Study of the Bruton Tyrosine Kinase (Btk) Inhibitor, Ibrutinib (PCI-32765) in Patients with Relapsed or Relapsed/Refractory Multiple Myeloma (MM)

Ravi Vij, MD, Betty Y. Chang, PhD, Jesus G. Berdeja, MD, Carol Ann Huff, M.D., Nikoletta Lendvai, MD PhD, Yu-Tzu Tai, PhD, Stella Chang, Davina Moussa, Joseph J. Buggy, PhD, Laurence Elias, MD, Paul G. Richardson, MD
Journal: Blood
Blood (2012) 120 (21): 4039.
https://doi.org/10.1182/blood.V120.21.4039.4039
Published: 2012
Journal Articles

Potent Anti-Leukemic Activity of a Cationic Lipid-DNA Complex.

Zachary Herse, BSc, Stella Chang, MSc, Denny Liggitt, DVM, PhD, Jeffery Fairman, PhD, David F. Claxton, MD
Journal: Blood
Blood (2007) 110 (11): 4891.
https://doi.org/10.1182/blood.V110.11.4891.4891
Published: 2007