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Susan K. Rathe
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Journal Articles

NRAS G12V oncogene facilitates self-renewal in a murine model of acute myelogenous leukemia

Zohar Sachs, Rebecca S. LaRue, Hanh T. Nguyen, Karen Sachs, Klara E. Noble, Nurul Azyan Mohd Hassan, Ernesto Diaz-Flores, Susan K. Rathe, Aaron L. Sarver, Sean C. Bendall, Ngoc A. Ha, Miechaleen D. Diers, Garry P. Nolan, Kevin M. Shannon, David A. Largaespada
Journal: Blood
Blood (2014) 124 (22): 3274–3283.
https://doi.org/10.1182/blood-2013-08-521708
Published: 2014
Includes: Supplemental data
Journal Articles

Ras-Pathway Inhibition With Targeted Therapies Abrogates Self-Renewal In Acute Myelogenous Leukemia

Rebecca S. LaRue, PhD, Hanh Nguyen, Karen Sachs, Nurul Azyan Mohd Hassan, Ernesto Diaz-Flores, PhD, Susan K. Rathe, Aaron G. Sarver, Ph.D., Sean C. Bendall, Ngoc A. Ha, Miechaleen D. Diers, B.S., Garry P. Nolan, PhD, Kevin Shannon, MD, Zohar Sachs, MD, PhD, David A. Largaespada, PhD
Journal: Blood
Blood (2013) 122 (21): 819.
https://doi.org/10.1182/blood.V122.21.819.819
Published: 2013
Journal Articles

Activated NRAS Mediates Self-Renewal Capacity in AML by Facilitating the Mll/AF9 -Specified Gene Expression Signature

Zohar Sachs, MD, PhD, Hanh Nguyen, Nurul Azyan Mohd Hassan, Susan K Rathe, Karen Sachs, Ph. D., Ernesto Diaz-Flores, PhD, Sean C Bendall, PhD, Miechaleen D Diers, Garry P. Nolan, Ph. D., Kevin M. Shannon, MD, David A. Largaespada, PhD
Journal: Blood
Blood (2012) 120 (21): 5116.
https://doi.org/10.1182/blood.V120.21.5116.5116
Published: 2012
Journal Articles

Delineating Critical Effectors of Remission Induction in a Mouse Model of AML

Zohar Sachs, MD, PhD, Susan K. Rathe, Ernesto Diaz-Flores, PhD, Miechaleen D Diers, Kevin M. Shannon, MD, David A. Largaespada, PhD
Journal: Blood
Blood (2011) 118 (21): 5232.
https://doi.org/10.1182/blood.V118.21.5232.5232
Published: 2011
Journal Articles

RNA-Sequencing of the Transcriptome of Ara-C Resistant Murine AML Cell Lines Identifies Potential Drug Targets

Susan K. Rathe, Christopher B. Stoltenberg, David A. Largaespada, PhD
Journal: Blood
Blood (2011) 118 (21): 2489.
https://doi.org/10.1182/blood.V118.21.2489.2489
Published: 2011
Journal Articles

Mechanisms of Relapse Following Targeted Therapy in An NRAS G12V and Mll-AF9 Driven Mouse Model of AML

Craig E. Eckfeldt, MD, PhD, Ernesto Diaz-Flores, PhD, Michaeleen D. Diers, Susan K. Rathe, Kevin M. Shannon, MD, David A. Largaespada, PhD
Journal: Blood
Blood (2011) 118 (21): 2620.
https://doi.org/10.1182/blood.V118.21.2620.2620
Published: 2011
Journal Articles

Oncogene Withdrawal Selectively Alters Phosphoprotein States and Shifts Differentiation Status In Myeloid Leukemia Subpopulations

Zohar Sachs, MD, PhD, Ernesto Diaz-Flores, PhD, Miechaleen D Diers, Karen Sachs, Sean C Bendall, PhD, Harris G Fienberg, Susan K Rathe, Garry P. Nolan, Ph.D., Kevin Shannon, MD, David Largaespada, PhD
Journal: Blood
Blood (2010) 116 (21): 3160.
https://doi.org/10.1182/blood.V116.21.3160.3160
Published: 2010
Journal Articles

A Screen for Drugs Showing Specific Co-Resistance or Hyper-Sensitivity Upon the Acquisition of Ara-C Resistance In AML

Susan K Rathe, David Largaespada, PhD
Journal: Blood
Blood (2010) 116 (21): 1844.
https://doi.org/10.1182/blood.V116.21.1844.1844
Published: 2010
Journal Articles

A Murine AML Model for the Development of Resistance to NRAS(G12V) Oncogene Repression and/or Ara-C Treatment in Vivo

Won-IL Kim, Ph.D., Susan K Rathe, Miechaleen D Diers, David A Largaespada, Ph.D
Journal: Blood
Blood (2008) 112 (11): 4030.
https://doi.org/10.1182/blood.V112.11.4030.4030
Published: 2008
Journal Articles

A Novel Microarray Gene Expression Analysis of Murine AML Cell Lines Provides Clues to the Development of Drug Resistance to Ara-C

Susan K Rathe, David Largaespada, PhD
Journal: Blood
Blood (2008) 112 (11): 5017.
https://doi.org/10.1182/blood.V112.11.5017.5017
Published: 2008
Journal Articles

Genetic Mechanisms of Cytarabine Resistance in Leukemia: Cell Culture and Mouse Transplantation Models.

Bin Yin, PhD, Miechaleen D. Diers, Bachelor, Susan K. Rathe, Bachelor, Scott W. Lowe, PhD, David A. Largaespada, PhD
Journal: Blood
Blood (2006) 108 (11): 4374.
https://doi.org/10.1182/blood.V108.11.4374.4374
Published: 2006