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Journal Articles

Establishment of Durable Chimerism with Minimal GvHD in Highly Mismatched Recipients Receiving an Investigational Facilitated Allo-HSCT

Joseph R. Leventhal, Nancy R. Krieger, Anat R Tambur, Kristi Schneider, Jordan Olsen, Suzanne T Ildstad

Blood (2021) 138 (Supplement 1): 911.

https://doi.org/10.1182/blood-2021-153231

Published: 2021

Journal Articles

Hematopoietic Mononuclear Cell Transplant with Minimal Gvhd in up to Completely Mismatched Unrelated Recipients

Suzanne T Ildstad, MD

Blood (2019) 134 (Supplement_1): 3243.

https://doi.org/10.1182/blood-2019-130943

Published: 2019

Journal Articles

Use of a Processed Hematopoietic Stem Cell Product (FCRx) in Unmatched Related and Unrelated Donor — Recipient Pairs Is Associated with High Levels of Donor Chimerism and Donor-Specific Tolerance to Kidney Allografts

Joseph R. Leventhal, MD PhD, John P. Galvin, MDMS,MPH, James Mathew, PhD, Lorenzo Gallon, MD, Kadiyala Ravindra, MD, Mitchell E. Horwitz, MD, Michael Abecassis, MD, MBA, Suzanne T Ildstad, MD

Blood (2018) 132 (Supplement 1): 202.

https://doi.org/10.1182/blood-2018-99-118832

Published: 2018

Journal Articles

Immune Reconstitution in Recipients of Living Donor Kidney/Hematopoietic Stem + Facilitating Cell Transplants

Joseph R. Leventhal, MD PhD, Mary J Elliott, Esma S. Yolcu, PhD, Larry D. Bozulic, PhD, David J Tollerud, MD MPH, James M Mathew, PhD, Iwona M Konieczna, Michael G Ison, MD, Mark Badder, Michael M I Abecassis, MD MBA, Joshua Miller, MD, Suzanne T. Ildstad, MD

Blood (2014) 124 (21): 191.

https://doi.org/10.1182/blood.V124.21.191.191

Published: 2014

Journal Articles

Human Facilitating Cells (FCs): Two Distinct, Complementary, and Synergistic CD56 Subpopulations That Uniquely Define FC Function

Yiming Huang, MD, Mary J Elliott, BS, Thomas O Miller, BS, Janina Ratajczak, MD PhD, Larry D Bozulic, PhD, Yujie Wen, MD PhD, Hong Xu, MD, Mariusz Z Ratajczak, MD PhD, Suzanne T. Ildstad, MD

Blood (2014) 124 (21): 1106.

https://doi.org/10.1182/blood.V124.21.1106.1106

Published: 2014

Journal Articles

CD8 + TCR - Bone Marrow Facilitating Cells Prime Migration and Enhance Homing of Hematopoietic Stem Cells

Yujie Wen, MD PhD, Yiming Huang, MD, Thomas O Miller, BS, Mariusz Z Ratajczak, MD PhD, Suzanne T Ildstad, MD

Blood (2014) 124 (21): 2412.

https://doi.org/10.1182/blood.V124.21.2412.2412

Published: 2014

Journal Articles

Evaluation Of Immunocompentence In Tolerant Chimeric Recipients Of Hematopoietic Stem Cell/Renal Transplants

Joseph Leventhal, MD, PhD, Larry D Bozulic, PhD, Mark D. Badder, MSc, Mary Jane Elliott, M.S., Michael N Issa, M.D., James Mathew, M.D., Iwona Konieczna, Suzanne T. Ildstad, MD

Blood (2013) 122 (21): 4483.

https://doi.org/10.1182/blood.V122.21.4483.4483

Published: 2013

Journal Articles

Chimerism and Tolerance Without Gvhd In Mismatched Recipients Of Combined Hematopoietic Stem Cell/Kidney Transplants: Donor-Specific Hyporeactivity Is Not a Reliable Biomarker For Tolerance

Joseph Leventhal, MD, PhD, Michael Abecassis, MD, Joshua Miller, MD, Lorenzo Gallon, MD, David J. Tollerud, MD, MPH, Mary Jane Elliott, M.S., Suzanne T. Ildstad, M.D.

Blood (2013) 122 (21): 912.

https://doi.org/10.1182/blood.V122.21.912.912

Published: 2013

Journal Articles

Update On Phase 2 Clinical Trial To Induce Tolerance In Mismatched Living Donor Renal Transplant Recipients

Joseph Leventhal, MD, PhD, Michael Abecassis, MD, Joshua Miller, MD, Lorenzo Gallon, MD, David J Tollerud, MD, MPH, Suzanne T. Ildstad, MD

Blood (2013) 122 (21): 4622.

https://doi.org/10.1182/blood.V122.21.4622.4622

Published: 2013

Journal Articles

The Early Rejection of Allogeneic BMC by Macrophages or NK Cells Is TRIF Signaling Dependent

Hong Xu, MD, Jun Yan, MD, PhD, Yiming Huang, MD, Suzanne T Ildstad

Blood (2012) 120 (21): 1883.

https://doi.org/10.1182/blood.V120.21.1883.1883

Published: 2012

Journal Articles

DOCK2 Is Critical for FC to Induce Regulatory T Cells

Yujie Wen, Mary J Elliott, Yiming Huang, Deborah R Corbin, Thomas O Miller, Suzanne T Ildstad

Blood (2012) 120 (21): 1885.

https://doi.org/10.1182/blood.V120.21.1885.1885

Published: 2012

Journal Articles

Human CD8 + / TCR − / CD56 dim / - Facilitating Cells Facilitate Homing and Engraftment of Human HSC in Vivo

Yiming Huang, MD, Mary J Elliott, Thomas Miller, Deborah R Corbin, Larry D. Bozulic, PhD, Hong Xu, MD, Yujie Wen, Maryam Jazayeri, PhD, Suzanne T. Ildstad, MD

Blood (2012) 120 (21): 4093.

https://doi.org/10.1182/blood.V120.21.4093.4093

Published: 2012

Journal Articles

The CXCR4 Antagonist AMD 3100 Induces Rapid Mobilization of Facilitating Cells and Hematopoietic Stem Cells in Mice

Hong Xu, MD, Ziqiang Zhu, MD, Yiming Huang, MD, Suzanne T. Ildstad, MD

Blood (2011) 118 (21): 4694.

https://doi.org/10.1182/blood.V118.21.4694.4694

Published: 2011

Journal Articles

Durable Chimerism, Absence of Graft-Versus-Host Disease and the Induction of Donor Specific Tolerance in Recipients of HLA Disparate Living Donor Kidney Transplants and Therapeutic Cell Transfer

Joseph Leventhal, Michael Abecassis, M.D., Joshua Miller, M.D., Lorenzo Gallon, M.D., Kadiyala Ravindra, M.D., David J Tollerud, MD, MPH, Bradley J King, Geoffrey Herzig, M.D., Roger Herzig, MD, Suzanne T Ildstad, MD

Blood (2011) 118 (21): 832.

https://doi.org/10.1182/blood.V118.21.832.832

Published: 2011

Journal Articles

Flt3-Ligand Plays a Critical Role in Development and Function of CD8 + /TCR − Facilitating Cells in Bone Marrow,

Yiming Huang, MD, Thomas Miller, Hong Xu, MD, Yujie Wen, M.D., Ph.D., Suzanne T Ildstad, MD

Blood (2011) 118 (21): 4003.

https://doi.org/10.1182/blood.V118.21.4003.4003

Published: 2011

Journal Articles

Chimerism, Lymphocyte Recovery, and the Absence of Graft-Versus-Host Disease in Recipients of Mismatched Unrelated Combined Kidney and HSC Transplants for Tolerance Induction

Joseph Leventhal, Paul A Cardenas, Mary J Elliott, Suzanne T Ildstad

Blood (2011) 118 (21): 1969.

https://doi.org/10.1182/blood.V118.21.1969.1969

Published: 2011

Journal Articles

Critical Role for DOCK2 in CD8 + /TCR − Graft Facilitating Cells Enhancing Engraftment of Hematopoietic Stem Cells

Yujie Wen, Mary J Elliott, Yiming Huang, Deborah R Corbin, Yoshinori Fukui, Mariusz Z Ratajczak, Suzanne T Ildstad

Blood (2011) 118 (21): 142.

https://doi.org/10.1182/blood.V118.21.142.142

Published: 2011

Journal Articles

CD8α + plasmacytoid precursor DCs induce antigen-specific regulatory T cells that enhance HSC engraftment in vivo

Yiming Huang, Larry D. Bozulic, Thomas Miller, Hong Xu, Lala-Rukh Hussain, Suzanne T. Ildstad

Blood (2011) 117 (8): 2494–2505.

https://doi.org/10.1182/blood-2010-06-291187

Published: 2011

Includes: Supplemental data

Journal Articles

Human CD8 + /TCR − /CD56 dim/− facilitating Cells Enhance Engraftment of HSC In NOD/SCID/IL2rγ null Recipients.

Yiming Huang, MD, Mary J Elliott, Deborah M Ramsey, Thomas Miller, Larry D Bozulic, Ashley A Ocker, Bradley J King, Suzanne T. Ildstad, MD

Blood (2010) 116 (21): 3709.

https://doi.org/10.1182/blood.V116.21.3709.3709

Published: 2010

Journal Articles

A Critical Role for Innate Immunity In Allogeneic Hematopoietic Cell Rejection Via the TLR4/TRIF Pathway

Hong Xu, MD, Jun Yan, MD, PhD, Ziqiang Zhu, MD, Yiming Huang, MD, Yujie Wen, MD, PhD, Larry D Bozulic, PhD, Suzanne T. Ildstad, MD

Blood (2010) 116 (21): 77.

https://doi.org/10.1182/blood.V116.21.77.77

Published: 2010

NARROW

Establishment of Durable Chimerism with Minimal GvHD in Highly Mismatched Recipients Receiving an Investigational Facilitated Allo-HSCT

Hematopoietic Mononuclear Cell Transplant with Minimal Gvhd in up to Completely Mismatched Unrelated Recipients

Use of a Processed Hematopoietic Stem Cell Product (FCRx) in Unmatched Related and Unrelated Donor — Recipient Pairs Is Associated with High Levels of Donor Chimerism and Donor-Specific Tolerance to Kidney Allografts

Immune Reconstitution in Recipients of Living Donor Kidney/Hematopoietic Stem + Facilitating Cell Transplants

Human Facilitating Cells (FCs): Two Distinct, Complementary, and Synergistic CD56 Subpopulations That Uniquely Define FC Function

CD8 + TCR - Bone Marrow Facilitating Cells Prime Migration and Enhance Homing of Hematopoietic Stem Cells

Evaluation Of Immunocompentence In Tolerant Chimeric Recipients Of Hematopoietic Stem Cell/Renal Transplants

Chimerism and Tolerance Without Gvhd In Mismatched Recipients Of Combined Hematopoietic Stem Cell/Kidney Transplants: Donor-Specific Hyporeactivity Is Not a Reliable Biomarker For Tolerance

Update On Phase 2 Clinical Trial To Induce Tolerance In Mismatched Living Donor Renal Transplant Recipients

The Early Rejection of Allogeneic BMC by Macrophages or NK Cells Is TRIF Signaling Dependent

DOCK2 Is Critical for FC to Induce Regulatory T Cells

Human CD8 + / TCR − / CD56 dim / - Facilitating Cells Facilitate Homing and Engraftment of Human HSC in Vivo

The CXCR4 Antagonist AMD 3100 Induces Rapid Mobilization of Facilitating Cells and Hematopoietic Stem Cells in Mice

Durable Chimerism, Absence of Graft-Versus-Host Disease and the Induction of Donor Specific Tolerance in Recipients of HLA Disparate Living Donor Kidney Transplants and Therapeutic Cell Transfer

Flt3-Ligand Plays a Critical Role in Development and Function of CD8 + /TCR − Facilitating Cells in Bone Marrow,

Chimerism, Lymphocyte Recovery, and the Absence of Graft-Versus-Host Disease in Recipients of Mismatched Unrelated Combined Kidney and HSC Transplants for Tolerance Induction

Critical Role for DOCK2 in CD8 + /TCR − Graft Facilitating Cells Enhancing Engraftment of Hematopoietic Stem Cells

CD8α + plasmacytoid precursor DCs induce antigen-specific regulatory T cells that enhance HSC engraftment in vivo

Human CD8 + /TCR − /CD56 dim/− facilitating Cells Enhance Engraftment of HSC In NOD/SCID/IL2rγ null Recipients.

A Critical Role for Innate Immunity In Allogeneic Hematopoietic Cell Rejection Via the TLR4/TRIF Pathway

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American Society of Hematology

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American Society of Hematology

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