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Journal Articles

Human Facilitating Cells (FCs): Two Distinct, Complementary, and Synergistic CD56 Subpopulations That Uniquely Define FC Function

Yiming Huang, MD, Mary J Elliott, BS, Thomas O Miller, BS, Janina Ratajczak, MD PhD, Larry D Bozulic, PhD, Yujie Wen, MD PhD, Hong Xu, MD, Mariusz Z Ratajczak, MD PhD, Suzanne T. Ildstad, MD

Blood (2014) 124 (21): 1106.

https://doi.org/10.1182/blood.V124.21.1106.1106

Published: 2014

Journal Articles

CD8 + TCR - Bone Marrow Facilitating Cells Prime Migration and Enhance Homing of Hematopoietic Stem Cells

Yujie Wen, MD PhD, Yiming Huang, MD, Thomas O Miller, BS, Mariusz Z Ratajczak, MD PhD, Suzanne T Ildstad, MD

Blood (2014) 124 (21): 2412.

https://doi.org/10.1182/blood.V124.21.2412.2412

Published: 2014

Journal Articles

The Early Rejection of Allogeneic BMC by Macrophages or NK Cells Is TRIF Signaling Dependent

Hong Xu, MD, Jun Yan, MD, PhD, Yiming Huang, MD, Suzanne T Ildstad

Blood (2012) 120 (21): 1883.

https://doi.org/10.1182/blood.V120.21.1883.1883

Published: 2012

Journal Articles

DOCK2 Is Critical for FC to Induce Regulatory T Cells

Yujie Wen, Mary J Elliott, Yiming Huang, Deborah R Corbin, Thomas O Miller, Suzanne T Ildstad

Blood (2012) 120 (21): 1885.

https://doi.org/10.1182/blood.V120.21.1885.1885

Published: 2012

Journal Articles

Human CD8 + / TCR − / CD56 dim / - Facilitating Cells Facilitate Homing and Engraftment of Human HSC in Vivo

Yiming Huang, MD, Mary J Elliott, Thomas Miller, Deborah R Corbin, Larry D. Bozulic, PhD, Hong Xu, MD, Yujie Wen, Maryam Jazayeri, PhD, Suzanne T. Ildstad, MD

Blood (2012) 120 (21): 4093.

https://doi.org/10.1182/blood.V120.21.4093.4093

Published: 2012

Journal Articles

The CXCR4 Antagonist AMD 3100 Induces Rapid Mobilization of Facilitating Cells and Hematopoietic Stem Cells in Mice

Hong Xu, MD, Ziqiang Zhu, MD, Yiming Huang, MD, Suzanne T. Ildstad, MD

Blood (2011) 118 (21): 4694.

https://doi.org/10.1182/blood.V118.21.4694.4694

Published: 2011

Journal Articles

Flt3-Ligand Plays a Critical Role in Development and Function of CD8 + /TCR − Facilitating Cells in Bone Marrow,

Yiming Huang, MD, Thomas Miller, Hong Xu, MD, Yujie Wen, M.D., Ph.D., Suzanne T Ildstad, MD

Blood (2011) 118 (21): 4003.

https://doi.org/10.1182/blood.V118.21.4003.4003

Published: 2011

Journal Articles

Critical Role for DOCK2 in CD8 + /TCR − Graft Facilitating Cells Enhancing Engraftment of Hematopoietic Stem Cells

Yujie Wen, Mary J Elliott, Yiming Huang, Deborah R Corbin, Yoshinori Fukui, Mariusz Z Ratajczak, Suzanne T Ildstad

Blood (2011) 118 (21): 142.

https://doi.org/10.1182/blood.V118.21.142.142

Published: 2011

Journal Articles

CD8α + plasmacytoid precursor DCs induce antigen-specific regulatory T cells that enhance HSC engraftment in vivo

Yiming Huang, Larry D. Bozulic, Thomas Miller, Hong Xu, Lala-Rukh Hussain, Suzanne T. Ildstad

Blood (2011) 117 (8): 2494–2505.

https://doi.org/10.1182/blood-2010-06-291187

Published: 2011

Includes: Supplemental data

Journal Articles

Human CD8 + /TCR − /CD56 dim/− facilitating Cells Enhance Engraftment of HSC In NOD/SCID/IL2rγ null Recipients.

Yiming Huang, MD, Mary J Elliott, Deborah M Ramsey, Thomas Miller, Larry D Bozulic, Ashley A Ocker, Bradley J King, Suzanne T. Ildstad, MD

Blood (2010) 116 (21): 3709.

https://doi.org/10.1182/blood.V116.21.3709.3709

Published: 2010

Journal Articles

A Critical Role for Innate Immunity In Allogeneic Hematopoietic Cell Rejection Via the TLR4/TRIF Pathway

Hong Xu, MD, Jun Yan, MD, PhD, Ziqiang Zhu, MD, Yiming Huang, MD, Yujie Wen, MD, PhD, Larry D Bozulic, PhD, Suzanne T. Ildstad, MD

Blood (2010) 116 (21): 77.

https://doi.org/10.1182/blood.V116.21.77.77

Published: 2010

Journal Articles

Chimeric Regulatory T cells Enhance HSC Engraftment in An Antigen-Specific Fashion.

Yiming Huang, M.D., Larry D Bozulic, Ph.D, Thomas Miller, B.S., Hong Xu, M.D., Yujie Wen, Ph.D, Lala-Rukh Hussain, B.S., Suzanne T Ildstad, M.D.

Blood (2009) 114 (22): 2424.

https://doi.org/10.1182/blood.V114.22.2424.2424

Published: 2009

Journal Articles

Innate Immunity Is Responsible for Early Allorejection of Donor Bone Marrow Cells.

Hong Xu, M.D., Jun Yan, Ziqiang Zhu, Lala-Rukh Hussain, B.S., Yiming Huang, M.D., Larry D. Bozulic, PhD, Suzanne T Ildstad

Blood (2009) 114 (22): 3523.

https://doi.org/10.1182/blood.V114.22.3523.3523

Published: 2009

Journal Articles

Bone Marrow Cell Rejection by Innate Immune Pathways Is Exclusively Dependent On the TRIF Pathway.

Hong Xu, M.D., Jun Yan, Ziqiang Zhu, Lala-Rukh Hussain, B.S., Yiming Huang, M.D., Yujie Wen, Ph.D, Suzanne T Ildstad

Blood (2009) 114 (22): 3526.

https://doi.org/10.1182/blood.V114.22.3526.3526

Published: 2009

Journal Articles

Sensitization to Minor Histocompatibility Antigens Poses a Barrier in Transplantation and Can Be Prevented by CD154:CD40 Co-Stimulatory Blockade.

Hong Xu, M.D., Yiming Huang, M.D., Lala-Rukh Hussain, B.S., Suzanne T Ildstad, M.D.

Blood (2008) 112 (11): 2317.

https://doi.org/10.1182/blood.V112.11.2317.2317

Published: 2008

Journal Articles

CD8 + /TCR − Facilitating Cells Induce Generation of Regulatory T cells in Vivo: Chimeric Regulatory T Cells are Antigen-Specific and Enhance Engraftment of Allogeneic HSC in Non-Obese Diabetic (NOD) Mice.

Yiming Huang, M.D., Larry D Bozulic, Ph.D, Thomas Miller, B.S., Hong Xu, M.D., Lala-Rukh Hussain, B.S., Suzanne T. Ildstad, MD

Blood (2008) 112 (11): 2318.

https://doi.org/10.1182/blood.V112.11.2318.2318

Published: 2008

Journal Articles

Costimulatory Blockade Enhances Engraftment and Prevents Anti-Donor Antibody Generation in Nonmyeloablative Conditioned Prediabetic NOD Mice

Larry D Bozulic, Ph.D, Hong Xu, M.D., Yiming Huang, M.D., Suzanne T Ildstad, M.D.

Blood (2008) 112 (11): 4597.

https://doi.org/10.1182/blood.V112.11.4597.4597

Published: 2008

Journal Articles

Costimulatory blockade of CD154-CD40 in combination with T-cell lymphodepletion results in prevention of allogeneic sensitization

Hong Xu, Jun Yan, Yiming Huang, Paula M. Chilton, Chuanlin Ding, Carrie L. Schanie, Li Wang, Suzanne T. Ildstad

Blood (2008) 111 (6): 3266–3275.

https://doi.org/10.1182/blood-2006-10-053801

Published: 2008

Includes: Supplemental data

Journal Articles

CD154 Blockade Prevents Allosensitization through Inhibiting Both T- and B-Cell Activation and Decreasing Expression of IFN-γ and IL-10 in T-Cells.

Hong Xu, MD, Jun Yan, MD PhD, Yiming Huang, MD, Paula M. Chilton, PhD, Michael K. Tanner, MS, Lala-Rukh Hussain, BS, Suzanne T. Ildstad, MD

Blood (2007) 110 (11): 1346.

https://doi.org/10.1182/blood.V110.11.1346.1346

Published: 2007

Journal Articles

Chimerism May Prolong Islet Allograft Acceptance through the Preservation of CD4 + CD25 + FoxP3 + T reg in Diabetic NOD Mice.

Larry D. Bozulic, PhD, Yiming Huang, M.D., Hong Xu, M.D., Safinur Atay, M.S., Suzanne T. Ildstad, M.D.

Blood (2007) 110 (11): 3257.

https://doi.org/10.1182/blood.V110.11.3257.3257

Published: 2007

NARROW

Human Facilitating Cells (FCs): Two Distinct, Complementary, and Synergistic CD56 Subpopulations That Uniquely Define FC Function

CD8 + TCR - Bone Marrow Facilitating Cells Prime Migration and Enhance Homing of Hematopoietic Stem Cells

The Early Rejection of Allogeneic BMC by Macrophages or NK Cells Is TRIF Signaling Dependent

DOCK2 Is Critical for FC to Induce Regulatory T Cells

Human CD8 + / TCR − / CD56 dim / - Facilitating Cells Facilitate Homing and Engraftment of Human HSC in Vivo

The CXCR4 Antagonist AMD 3100 Induces Rapid Mobilization of Facilitating Cells and Hematopoietic Stem Cells in Mice

Flt3-Ligand Plays a Critical Role in Development and Function of CD8 + /TCR − Facilitating Cells in Bone Marrow,

Critical Role for DOCK2 in CD8 + /TCR − Graft Facilitating Cells Enhancing Engraftment of Hematopoietic Stem Cells

CD8α + plasmacytoid precursor DCs induce antigen-specific regulatory T cells that enhance HSC engraftment in vivo

Human CD8 + /TCR − /CD56 dim/− facilitating Cells Enhance Engraftment of HSC In NOD/SCID/IL2rγ null Recipients.

A Critical Role for Innate Immunity In Allogeneic Hematopoietic Cell Rejection Via the TLR4/TRIF Pathway

Chimeric Regulatory T cells Enhance HSC Engraftment in An Antigen-Specific Fashion.

Innate Immunity Is Responsible for Early Allorejection of Donor Bone Marrow Cells.

Bone Marrow Cell Rejection by Innate Immune Pathways Is Exclusively Dependent On the TRIF Pathway.

Sensitization to Minor Histocompatibility Antigens Poses a Barrier in Transplantation and Can Be Prevented by CD154:CD40 Co-Stimulatory Blockade.

CD8 + /TCR − Facilitating Cells Induce Generation of Regulatory T cells in Vivo: Chimeric Regulatory T Cells are Antigen-Specific and Enhance Engraftment of Allogeneic HSC in Non-Obese Diabetic (NOD) Mice.

Costimulatory Blockade Enhances Engraftment and Prevents Anti-Donor Antibody Generation in Nonmyeloablative Conditioned Prediabetic NOD Mice

Costimulatory blockade of CD154-CD40 in combination with T-cell lymphodepletion results in prevention of allogeneic sensitization

CD154 Blockade Prevents Allosensitization through Inhibiting Both T- and B-Cell Activation and Decreasing Expression of IFN-γ and IL-10 in T-Cells.

Chimerism May Prolong Islet Allograft Acceptance through the Preservation of CD4 + CD25 + FoxP3 + T reg in Diabetic NOD Mice.

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American Society of Hematology

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American Society of Hematology

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