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Journal Articles

Whole Exome Sequencing Analysis of Diffuse Large B-Cell Lymphoma That Progressed to Central Nervous System

Tomotaka Suzuki, Rui Yokomori, Takaomi Sanda, Hiroki Yano, Takaki Kikuchi, Takashi Kanamori, Atsushi Inagaki, Takashi Yoshida, Satoshi Kayukawa, Yoshiko Oshima, Hirokazu Sasaki, Shiori Kinoshita, Tomoko Narita, Ayako Masaki, Masaki Ri, Shigeru Kusumoto, Hirokazu Komatsu, Hiroshi Inagaki, Shinsuke Iida

Blood (2023) 142 (Supplement 1): 1632.

https://doi.org/10.1182/blood-2023-174341

Published: 2023

Journal Articles

Acute Anemic Stress Is Modulated By Intercellular Mitochondria Transport from Erythroblastic Island Macrophages to Early Erythroblasts Via CD47-Sirpα Interactions

Chong Yang, Rui Yokomori, Lee Hui Chua, Takaomi Sanda, Toshio Suda

Blood (2022) 140 (Supplement 1): 2424.

https://doi.org/10.1182/blood-2022-157480

Published: 2022

Journal Articles

Roles of the SWI/SNF Chromatin Remodelling Factors in Sustaining Oncogenic Transcription Program in T-Cell Acute Lymphoblastic Leukaemia

Hyoju Kim, Tze King Tan, Xiao Zi Huang, Jolynn Ong, Rui Yokomori, Allen Eng Juh Yeoh, Takaomi Sanda, Shi Hao Tan

Blood (2022) 140 (Supplement 1): 5896–5897.

https://doi.org/10.1182/blood-2022-162528

Published: 2022

Journal Articles

Super-Enhancer-Driven PPP1R15B As an Oncogenic and Potential Therapeutic Target in Multiple Myeloma

Sinan Xiong, Jianbiao Zhou, Tze King Tan, Sabrina Hui-Min Toh, Kalpnaa Balan, Yunlu Jia, Tae-Hoon Chung, Takaomi Sanda, Wee Joo Chng

Blood (2021) 138 (Supplement 1): 2209.

https://doi.org/10.1182/blood-2021-149006

Published: 2021

Journal Articles

Super-Enhancer-Driven TOX2 Mediates Oncogenesis in Natural Killer/T Cell Lymphoma

Jianbiao Zhou, MDPhD, Sabrina Hui Min Toh, BSc, Kalpnaa Balan, BSc, Tze King Tan, PhD, Yunlu Jia, MD, Jing Quan Lim, PhD, Choon Kiat Ong, PhDBSc, Soon Thye Lim, MBBS, MRCP, Tuan Zea Tan, Siok-Bian Ng, Takaomi Sanda, MD PhD, Wee-Joo Chng, MBBS, PhD FRCPath, FRCP

Blood (2020) 136 (Supplement 1): 17.

https://doi.org/10.1182/blood-2020-136244

Published: 2020

Journal Articles

Feed-forward regulatory loop driven by IRF4 and NF-κB in adult T-cell leukemia/lymphoma

Regina Wan Ju Wong, Tze King Tan, Stella Amanda, Phuong Cao Thi Ngoc, Wei Zhong Leong, Shi Hao Tan, Kaori Asamitsu, Yurina Hibi, Ryuzo Ueda, Takashi Okamoto, Takashi Ishida, Shinsuke Iida, Takaomi Sanda

Blood (2020) 135 (12): 934–947.

https://doi.org/10.1182/blood.2019002639

Published: 2020

Includes: Supplemental data

Journal Articles

Development of the First Transgenic Animal Model for IRF4-Induced Lymphoid Malignancy

Stella Amanda, MSc, BSc, Regina Wong, Tze King Tan, PhD, Muhammad Zulfaqar Ali, MSc, BSc, Yan Li, PhD, Zhi Yuan Gong, PhD, Shinsuke Iida, MD PhD, Takaomi Sanda, MD PhD

Blood (2019) 134 (Supplement_1): 1242.

https://doi.org/10.1182/blood-2019-129714

Published: 2019

Journal Articles

Super-Enhancer Profiling Identifies Novel Oncogenes and Therapeutic Targets in Multiple Myeloma

Jianbiao Zhou, MD PhD, Yunlu Jia, MD, Tze King Tan, PhD, Tae-Hoon Chung, PhD, Takaomi Sanda, MD PhD, Wee Joo Chng, MB ChB, PhD FRCP(UK), FRCPath, FAMS

Blood (2019) 134 (Supplement_1): 362.

https://doi.org/10.1182/blood-2019-124252

Published: 2019

Journal Articles

The enhancer RNA ARIEL activates the oncogenic transcriptional program in T-cell acute lymphoblastic leukemia

Shi Hao Tan, Wei Zhong Leong, Phuong Cao Thi Ngoc, Tze King Tan, Fatima Carla Bertulfo, Mei Chee Lim, Omer An, Zhenhua Li, Allen Eng Juh Yeoh, Melissa J. Fullwood, Daniel G. Tenen, Takaomi Sanda

Blood (2019) 134 (3): 239–251.

https://doi.org/10.1182/blood.2018874503

Published: 2019

Includes: Supplemental data

Journal Articles

Identification of Long Non-Coding RNAs Regulated By the TAL1 Complex in T-Cell Acute Lymphoblastic Leukemia

Shi Hao Tan, PhD, Phuong Cao Thi Ngoc, PhD, Wei Zhong Leong, BSc, Daniel G. Tenen, MD, Takaomi Sanda, MD PhD

Blood (2017) 130 (Supplement 1): 1201.

https://doi.org/10.1182/blood.V130.Suppl_1.1201.1201

Published: 2017

Journal Articles

ARID5B Activates the TAL1-Induced Core Regulatory Circuit and the MYC Oncogene in T-Cell Acute Lymphoblastic Leukemia

Wei Zhong Leong, BSc, Shi Hao Tan, PhD, Phuong Cao Thi Ngoc, PhD, Stella Amanda, Alice Wei Yee Yam, Wei-Siang Liau, Zhiyuan Gong, Lee N. Lawton, PhD, Daniel G. Tenen, MD, Takaomi Sanda, MD PhD

Blood (2017) 130 (Supplement 1): 2502.

https://doi.org/10.1182/blood.V130.Suppl_1.2502.2502

Published: 2017

Journal Articles

Enhancer profiling identifies critical cancer genes and characterizes cell identity in adult T-cell leukemia

Regina Wan Ju Wong, Phuong Cao Thi Ngoc, Wei Zhong Leong, Alice Wei Yee Yam, Tinghu Zhang, Kaori Asamitsu, Shinsuke Iida, Takashi Okamoto, Ryuzo Ueda, Nathanael S. Gray, Takashi Ishida, Takaomi Sanda

Blood (2017) 130 (21): 2326–2338.

https://doi.org/10.1182/blood-2017-06-792184

Published: 2017

Includes: Supplemental data

Journal Articles

RUNX1 in T-ALL: tumor suppressive or oncogenic?

Takaomi Sanda

Blood (2017) 130 (15): 1686–1688.

https://doi.org/10.1182/blood-2017-08-802181

Published: 2017

Journal Articles

Identification of Super-Enhancer-Associated Cancer Genes Provides Novel Therapeutic Targets in Adult T-Cell Leukemia/Lymphoma

Regina Wan Ju Wong, BSc, Phuong Thi Ngoc Cao, PhD, Wei Zhong Leong, BSc, Alice Wei Yee Yam, Bsc, Tinghu Zhang, PhD, Shinsuke Iida, MD PhD, Takashi Okamoto, MD PhD, Ryuzo Ueda, MD PhD, Nathanael S. Grey, PhD, Takashi Ishida, MD PhD, Takaomi Sanda, MD PhD

Blood (2016) 128 (22): 2720.

https://doi.org/10.1182/blood.V128.22.2720.2720

Published: 2016

Journal Articles

Anti-Leukemic Activity of the TYK2 Selective Inhibitor Ndi-031301 in T-Cell Acute Lymphoblastic Leukemia

Koshi Akahane, MD PhD, Zhaodong Li, PhD, Julia Etchin, PhD, Alla Berezovskaya, Evisa Gjini, PhD, Craig E Masse, PhD, Wenyan Miao, PhD, Jennifer Rocnik, PhD, Rosana Kapeller, MD PhD, Jeremy R Greenwood, PhD, Hong Tiv, Takaomi Sanda, MD PhD, David M Weinstock, MD, A. Thomas Look, MD

Blood (2016) 128 (22): 1596.

https://doi.org/10.1182/blood.V128.22.1596.1596

Published: 2016

Journal Articles

The KDM3A-KLF2-IRF4 Axis Maintains Myeloma Cell Survival

Hiroto Ohguchi, MD PhD, Teru Hideshima, MDPhD, Manoj Bhasin, PhD, Gullu Gorgun, PhD, Loredana Santo, MD, Michele Cea, MD, Naoya Mimura, MD PhD, Rikio Suzuki, MDPhD, Yu-Tzu Tai, PhD, Ruben D. Carrasco, MD PhD, Noopur S. Raje, MD, Paul G. Richardson, MD, Hideo Harigae, MD PhD, Takaomi Sanda, MD PhD, Kenneth C. Anderson, MD

Blood (2015) 126 (23): 3633.

https://doi.org/10.1182/blood.V126.23.3633.3633

Published: 2015

Journal Articles

HSP90 Inhibition Has Potent Activity Against T-Cell Acute Lymphoblastic Leukemia (T-ALL) Through Degradation Of TYK2 Kinase

Koshi Akahane, Takaomi Sanda, PhD, Marc R. Mansour, MD PhD FRCPath, Julia Etchin, PhD, Ng Cherry, David M. Weinstock, MD, Anthony Letai, MD, PhD, Daniel J. DeAngelo, MD, Ph.D, A. Thomas Look, MD

Blood (2013) 122 (21): 2528.

https://doi.org/10.1182/blood.V122.21.2528.2528

Published: 2013

Journal Articles

A Genetic Screen In Zebrafish Identified Dlst As a Potential Therapeutic Target For Human Acute T-Lymphoblastic Leukemia

Nicole M Anderson, PhD, Hongling Peng, MD, Daniel Helman, BS, Itrat Harrold, PhD, Takaomi Sanda, PhD, Trevor Grant, MS, Nicholas Nagykery, BS, Yasmina Samaha, Meng Le, PhD, Adam Amsterdam, PhD, Donna Neuberg, ScD, Marc R. Mansour, MD PhD FRCPath, Travis Denton, PhD, John Kanki, PhD, Anurag Singh, PhD, A. Thomas Look, MD, Hui Feng, PhD

Blood (2013) 122 (21): 1273.

https://doi.org/10.1182/blood.V122.21.1273.1273

Published: 2013

Journal Articles

The TAL1 Complex Represses the FBXW7 Tumor Suppressor Through Mir-223 in Human T-Cell Acute Lymphoblastic Leukemia

Marc R Mansour, MD FRCPath, Takaomi Sanda, MD, PhD, Lee N Lawton, PhD, Xiaoyu Li, MD, PhD, Taras Kreslavsky, PhD, Carl Novina, MD PhD, Harald von Boehmer, MD PhD, Richard Young, PhD, A. Thomas Look, M.D.

Blood (2012) 120 (21): 1296.

https://doi.org/10.1182/blood.V120.21.1296.1296

Published: 2012

Journal Articles

TYK2-STAT1 Pathway Positively Regulates BCL2 Gene Expression in T-Cell Acute Lymphoblastic Leukemia

Blood (2012) 120 (21): 1470.

https://doi.org/10.1182/blood.V120.21.1470.1470

Published: 2012

NARROW

Whole Exome Sequencing Analysis of Diffuse Large B-Cell Lymphoma That Progressed to Central Nervous System

Acute Anemic Stress Is Modulated By Intercellular Mitochondria Transport from Erythroblastic Island Macrophages to Early Erythroblasts Via CD47-Sirpα Interactions

Roles of the SWI/SNF Chromatin Remodelling Factors in Sustaining Oncogenic Transcription Program in T-Cell Acute Lymphoblastic Leukaemia

Super-Enhancer-Driven PPP1R15B As an Oncogenic and Potential Therapeutic Target in Multiple Myeloma

Super-Enhancer-Driven TOX2 Mediates Oncogenesis in Natural Killer/T Cell Lymphoma

Feed-forward regulatory loop driven by IRF4 and NF-κB in adult T-cell leukemia/lymphoma

Development of the First Transgenic Animal Model for IRF4-Induced Lymphoid Malignancy

Super-Enhancer Profiling Identifies Novel Oncogenes and Therapeutic Targets in Multiple Myeloma

The enhancer RNA ARIEL activates the oncogenic transcriptional program in T-cell acute lymphoblastic leukemia

Identification of Long Non-Coding RNAs Regulated By the TAL1 Complex in T-Cell Acute Lymphoblastic Leukemia

ARID5B Activates the TAL1-Induced Core Regulatory Circuit and the MYC Oncogene in T-Cell Acute Lymphoblastic Leukemia

Enhancer profiling identifies critical cancer genes and characterizes cell identity in adult T-cell leukemia

RUNX1 in T-ALL: tumor suppressive or oncogenic?

Identification of Super-Enhancer-Associated Cancer Genes Provides Novel Therapeutic Targets in Adult T-Cell Leukemia/Lymphoma

Anti-Leukemic Activity of the TYK2 Selective Inhibitor Ndi-031301 in T-Cell Acute Lymphoblastic Leukemia

The KDM3A-KLF2-IRF4 Axis Maintains Myeloma Cell Survival

HSP90 Inhibition Has Potent Activity Against T-Cell Acute Lymphoblastic Leukemia (T-ALL) Through Degradation Of TYK2 Kinase

A Genetic Screen In Zebrafish Identified Dlst As a Potential Therapeutic Target For Human Acute T-Lymphoblastic Leukemia

The TAL1 Complex Represses the FBXW7 Tumor Suppressor Through Mir-223 in Human T-Cell Acute Lymphoblastic Leukemia

TYK2-STAT1 Pathway Positively Regulates BCL2 Gene Expression in T-Cell Acute Lymphoblastic Leukemia

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American Society of Hematology

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ASH Publications

American Society of Hematology

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