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Journal Articles

The histone methyltransferase MLL1/KMT2A in monocytes drives coronavirus-associated coagulopathy and inflammation

Sriganesh B. Sharma, William J. Melvin, Christopher O. Audu, Monica Bame, Nicole Rhoads, Weisheng Wu, Yogendra Kanthi, Jason S. Knight, Reheman Adili, Michael A. Holinstat, Thomas W. Wakefield, Peter K. Henke, Bethany B. Moore, Katherine A. Gallagher, Andrea T. Obi

Blood (2023) 141 (7): 725–742.

https://doi.org/10.1182/blood.2022015917

Published: 2023

Includes: Supplemental data

Journal Articles

Calf muscle pump dysfunction and VTE risk

Andrea T. Obi, Thomas W. Wakefield

Blood (2021) 137 (23): 3161–3162.

https://doi.org/10.1182/blood.2021011145

Published: 2021

Journal Articles

E-Selectin Antagonist GMI-1271 Shows a Favorable Safety, PK and Bleeding Profile in Phase I Studies of Healthy Volunteers

Dana E. Angelini, MD, Sumana Devata, MD, Angela E. Hawley, Susan A. Blackburn, RN, MBA, Satwinder Grewal, Martina V Hemmer, MA, Henry Flanner, MS, William Kramer, PhD, William E Parker, Yu-Ling Li, MS, MD, Daniel Durant Myers, DVM, MPH, James B. Froehlich, MD MPH, John L Magnani, PhD, Helen M. Thackray, MD, Thomas W. Wakefield, MD, Suman L. Sood, MD MSCE

Blood (2016) 128 (22): 3826.

https://doi.org/10.1182/blood.V128.22.3826.3826

Published: 2016

Journal Articles

Biomarkers and Clinical Prediction Rules in the Diagnosis of Suspected Deep Vein Thrombosis: A Comparison of Cancer and Non-Cancer Patients

Jordan K. Schaefer, MD, Dana E. Angelini, MD, Angela Hawley, MS, Susan A. Blackburn, RN, MBA, Elizabeth Lusk, Thomas M. Braun, PhD, Thomas W. Wakefield, MD, Suman L. Sood, MD MSCE

Blood (2016) 128 (22): 3804.

https://doi.org/10.1182/blood.V128.22.3804.3804

Published: 2016

Journal Articles

First in Human Phase 1 Single Dose Escalation Studies of the E-Selectin Antagonist GMI-1271 Show a Favorable Safety, Pharmacokinetic, and Biomarker Profile

Sumana Devata, MD, Suman L. Sood, MD, Martina V Hemmer, MA, Henry Flanner, MS, William Kramer, PhD, Christine Nietubicz, Angela Hawley, Dana E Angelini, MD, Daniel Durant Myers, DVM, MPH, Susan Blackburn, James Froehlich, MD, Thomas W. Wakefield, MD, John L. Magnani, PhD, Helen M. Thackray, MD

Blood (2015) 126 (23): 1004.

https://doi.org/10.1182/blood.V126.23.1004.1004

Published: 2015

Journal Articles

The role of galectin-3 and galectin-3–binding protein in venous thrombosis

Elise P. DeRoo, Shirley K. Wrobleski, Evelyn M. Shea, Ramsey K. Al-Khalil, Angela E. Hawley, Peter K. Henke, Daniel D. Myers, Jr, Thomas W. Wakefield, Jose A. Diaz

Blood (2015) 125 (11): 1813–1821.

https://doi.org/10.1182/blood-2014-04-569939

Published: 2015

Includes: Supplemental data

Journal Articles

Neutrophils in Deep Venous Thrombosis

Thomas W. Wakefield, MD

Blood (2014) 124 (21): SCI-29.

https://doi.org/10.1182/blood.V124.21.SCI-29.SCI-29

Published: 2014

Journal Articles

Soluble P-Selectin and Age Adjusted D-Dimer As Predictive Biomarkers of Venous Thrombosis

Dana E Angelini, MD, Cathy Stabler, R.N., Angela E. Hawley, Kenneth E. Guire, M.S., Daniel Durant Myers, DVM,MPH, Susan Blackburn, R.N., Thomas W. Wakefield, MD, Suman L. Sood, MD

Blood (2014) 124 (21): 2863.

https://doi.org/10.1182/blood.V124.21.2863.2863

Published: 2014

Journal Articles

E-Selectin Inhibitor GMI-1271 Works in Combination with Low-Molecular Weight Heparin to Decrease Venous Thrombosis and Bleeding Risk in a Mouse Model

Daniel Durant Myers, DVM,MPH, Shirely K. Wrobleski, BS, Krus Kelsey, Diana Farris, Diaz A. Jose, MD, Henke K. Peter, MD, Suman L. Sood, MD, Thomas W. Wakefield, MD, John L. Magnani, PhD

Blood (2014) 124 (21): 593.

https://doi.org/10.1182/blood.V124.21.593.593

Published: 2014

Journal Articles

Biomarkers and Clinical Characteristics Of Patients With and Without DVT In The Intensive Care Unit (ICU)

Suman L. Sood, MD, Cathy Stabler, R.N., Angela E. Hawley, MS, Kenneth E. Guire, M.S., Susan Blackburn, R.N., Molly Oberdoerster, B.A., Mariam Khan, Jose A. Diaz, MD, Thomas W. Wakefield, MD

Blood (2013) 122 (21): 1124.

https://doi.org/10.1182/blood.V122.21.1124.1124

Published: 2013

Journal Articles

Prediction of Venous Thromboembolism (VTE) in Patients with Pancreatic Cancer Using Clinical Data, Biomarkers, and VTE Risk Models

Joshua M Ruch, MD, Emily Bellile, MS, Angela E. Hawley, MS, Michelle A. Anderson, MD, Thomas W. Wakefield, MD, Suman L. Sood, MD

Blood (2012) 120 (21): 3398.

https://doi.org/10.1182/blood.V120.21.3398.3398

Published: 2012

Journal Articles

Soluble P-Selectin for the Diagnosis of Deep Vein Thrombosis (DVT) in Cancer Patients

Suman L. Sood, MD, Cathy Stabler, R.N., Mariam Khan, Angela E. Hawley, Kenneth E. Guire, M.S., Thomas W. Wakefield, MD

Blood (2012) 120 (21): 3406.

https://doi.org/10.1182/blood.V120.21.3406.3406

Published: 2012

Journal Articles

Novel E-Selectin Antagonist GMI-1271 Decreases Venous Thrombosis without Increased Bleeding Potential in a Mouse Model

Daniel Durant Myers, Jr., DVM, MPH, Dorian L Culmer, DVM, Jose A. Diaz, MD, Angela E. Hawley, MS, Peter K. Henke, MD, Suman L. Sood, MD, Robert E Sigler, DVM, PhD, Andrea T Obi, MD, John T. Patton, PhD, Thomas W. Wakefield, MD, John L. Magnani, PhD

Blood (2012) 120 (21): 3422.

https://doi.org/10.1182/blood.V120.21.3422.3422

Published: 2012

Journal Articles

Pan-Selectin Antagonist, GMI-1070 Decreases Venous Thrombosis in a Mouse Model,

Daniel Durant Myers, Jr., DVM, MPH, Peter K. Henke, MD, Jose A. Diaz, MD, Shirley K. Wrobleski, BS, Angela E. Hawley, MS, Dallas Slack, BS, Thomas W. Wakefield, MD, John T. Patton, PhD, John L. Magnani

Blood (2011) 118 (21): 3273.

https://doi.org/10.1182/blood.V118.21.3273.3273

Published: 2011

Journal Articles

von Willebrand factor–mediated platelet adhesion is critical for deep vein thrombosis in mouse models

Alexander Brill, Tobias A. Fuchs, Anil K. Chauhan, Janie J. Yang, Simon F. De Meyer, Maria Köllnberger, Thomas W. Wakefield, Bernhard Lämmle, Steffen Massberg, Denisa D. Wagner

Blood (2011) 117 (4): 1400–1407.

https://doi.org/10.1182/blood-2010-05-287623

Published: 2011

Journal Articles

Neutrophil Extracellular Traps Induce Platelet Adhesion and Thrombus Formation.

Tobias Fuchs, PhD, Alexander Brill, MD, PhD, Daniel Dürschmied, MD, Daphne Schatzberg, John H. Hartwig, PhD, Daniel Myers, DVM, MPH, DACLAM, Thomas W. Wakefield, MD, Denisa D. Wagner, PhD

Blood (2009) 114 (22): 1345.

https://doi.org/10.1182/blood.V114.22.1345.1345

Published: 2009

Journal Articles

Evaluation of a Novel Anti-P-Selectin Aptamer ARC5690 On Venous Inflammation Following Acute Venous Thrombosis.

Jose Antonio Diaz, MD, Patrick A Lester, DVM, Jeffrey C Kurz, PhD, Shirley K Wrobleski, BS, LVT, Angela E Hawley, BS, Robert E Sigler, DVM, PhD, Thomas W Wakefield, MD, Robert G Schaub, PhD, Daniel Myers, DVM, MPH, DACLAM

Blood (2009) 114 (22): 3599.

https://doi.org/10.1182/blood.V114.22.3599.3599

Published: 2009

Journal Articles

Macrovascular thrombosis is driven by tissue factor derived primarily from the blood vessel wall

Sharlene M. Day, Jennifer L. Reeve, Brian Pedersen, Diana M Farris, Daniel D. Myers, Michael Im, Thomas W. Wakefield, Nigel Mackman, William P. Fay

Blood (2005) 105 (1): 192–198.

https://doi.org/10.1182/blood-2004-06-2225

Published: 2005

Journal Articles

Risk Factors Associated with Venous Thromboembolic Events in Patients with Malignancy.

Jules Lin, MD, Hang Li, BA, Thomas W. Wakefield, MD, Peter K. Henke, MD

Blood (2004) 104 (11): 2592.

https://doi.org/10.1182/blood.V104.11.2592.2592

Published: 2004

Journal Articles

D-Dimer, P-Selectin, and Microparticles: Novel Markers To Predict Deep Venous Thrombosis.

John E. Rectenwald, MD, Daniel D. Myers, DVM, MPH, Angela E. Hawley, BS, Marisa J. Linn, BGS, Chathen R. Gangireddy, BS, Peter K. Henke, MD, Kenneth E. Guire, MS, Alvin H. Schmaier, MD, Thomas W. Wakefield, MD

Blood (2004) 104 (11): 2607.

https://doi.org/10.1182/blood.V104.11.2607.2607

Published: 2004

NARROW

The histone methyltransferase MLL1/KMT2A in monocytes drives coronavirus-associated coagulopathy and inflammation

Calf muscle pump dysfunction and VTE risk

E-Selectin Antagonist GMI-1271 Shows a Favorable Safety, PK and Bleeding Profile in Phase I Studies of Healthy Volunteers

Biomarkers and Clinical Prediction Rules in the Diagnosis of Suspected Deep Vein Thrombosis: A Comparison of Cancer and Non-Cancer Patients

First in Human Phase 1 Single Dose Escalation Studies of the E-Selectin Antagonist GMI-1271 Show a Favorable Safety, Pharmacokinetic, and Biomarker Profile

The role of galectin-3 and galectin-3–binding protein in venous thrombosis

Neutrophils in Deep Venous Thrombosis

Soluble P-Selectin and Age Adjusted D-Dimer As Predictive Biomarkers of Venous Thrombosis

E-Selectin Inhibitor GMI-1271 Works in Combination with Low-Molecular Weight Heparin to Decrease Venous Thrombosis and Bleeding Risk in a Mouse Model

Biomarkers and Clinical Characteristics Of Patients With and Without DVT In The Intensive Care Unit (ICU)

Prediction of Venous Thromboembolism (VTE) in Patients with Pancreatic Cancer Using Clinical Data, Biomarkers, and VTE Risk Models

Soluble P-Selectin for the Diagnosis of Deep Vein Thrombosis (DVT) in Cancer Patients

Novel E-Selectin Antagonist GMI-1271 Decreases Venous Thrombosis without Increased Bleeding Potential in a Mouse Model

Pan-Selectin Antagonist, GMI-1070 Decreases Venous Thrombosis in a Mouse Model,

von Willebrand factor–mediated platelet adhesion is critical for deep vein thrombosis in mouse models

Neutrophil Extracellular Traps Induce Platelet Adhesion and Thrombus Formation.

Evaluation of a Novel Anti-P-Selectin Aptamer ARC5690 On Venous Inflammation Following Acute Venous Thrombosis.

Macrovascular thrombosis is driven by tissue factor derived primarily from the blood vessel wall

Risk Factors Associated with Venous Thromboembolic Events in Patients with Malignancy.

D-Dimer, P-Selectin, and Microparticles: Novel Markers To Predict Deep Venous Thrombosis.

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American Society of Hematology

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ASH Publications

American Society of Hematology

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