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Journal Articles

Phase I Study of Ixazomib Added to Chemotherapy in the Treatment of Acute Lymphoblastic Leukemia in Older Adults

Blood (2020) 136 (Supplement 1): 41–42.

https://doi.org/10.1182/blood-2020-139661

Published: 2020

Journal Articles

Redirecting T-Cells Against AML in a Multidimensional Targeting Space Using T-Cell Engaging Antibody Circuits (TEAC)

Eleanor Minogue, BSc, David Millar, PhD, Yan Chuan, PhD, Songfa Zhang, MD PhD, Korneel Grauwet, PhD, Mei Guo, Adam Langenbucher, Cyril H Benes, James Heather, PhD, Jeremy Minshull, PhD, Michael S. Lawrence, PhD, Rupa Narayan, David M. Langenau, PhD, Timothy A. Graubert, MD, Mark Cobbold

Blood (2019) 134 (Supplement_1): 2653.

https://doi.org/10.1182/blood-2019-127634

Published: 2019

Journal Articles

Potential Barriers to Clinical Trials of New Therapeutics for Myelodysplastic Syndromes: Wide Variation in Risk Definitions and Trial Enrollment Criteria

Andrew M. Brunner, MD, Jacqueline S. Garcia, R. Coleman Lindsley, MD, PhD, Gregory A. Abel, MD MPH, Donna S Neuberg, ScD, Richard M. Stone, MD, Timothy A. Graubert, MD, David P. Steensma, MD

Blood (2018) 132 (Supplement 1): 4378.

https://doi.org/10.1182/blood-2018-99-114356

Published: 2018

Journal Articles

Clinical Outcomes Following Frontline Chemotherapy for Patients with Myeloid Malignancies Harboring Splicing Factor Mutations

Evan C. Chen, MD, Gabriela S. Hobbs, MD, Philip C. Amrein, MD, Timothy A. Graubert, MD, Amir T. Fathi, MD, Andrew M. Brunner, MD

Blood (2018) 132 (Supplement 1): 4364.

https://doi.org/10.1182/blood-2018-99-111982

Published: 2018

Journal Articles

Single-Cell RNA-Seq Reveals AML Cellular Hierarchies Relevant to Clinical Outcomes and Immunity

Peter Van Galen, PhD, Volker Hovestadt, PhD, Marc Wadsworth II, Travis Hughes, Gabriel Kenneth Griffin, MD, Julia A. Verga, Jason Stephansky, Timothy J. Pastika, Jennifer Lombardi Story, Geraldine S. Pinkus, MD, Olga Pozdnyakova, MD PhD, Ilene Galinsky, Richard M. Stone, MD, Timothy A. Graubert, MD, Alex K. Shalek, PhD, Jon C. Aster, MD PhD, Andrew A. Lane, MD PhD, Bradley E. Bernstein, MD PhD

Blood (2018) 132 (Supplement 1): 542.

https://doi.org/10.1182/blood-2018-99-113502

Published: 2018

Journal Articles

Phase II Clinical Trial of Alisertib, an Aurora a Kinase Inhibitor, in Combination with Induction Chemotherapy in High-Risk, Untreated Patients with Acute Myeloid Leukemia

Blood (2018) 132 (Supplement 1): 766.

https://doi.org/10.1182/blood-2018-99-115145

Published: 2018

Journal Articles

Expression of B Cell Maturation Antigen (BCMA) and Transmembrane Activator and Caml Interactor (TACI) Are Correlated and Can be Targeted at Multiple Points during the Course of Multiple Myeloma

Allison O. Taylor, Matthew J. Frigault, MD, Felipe Bedoya, PhD, Michelle E. DeLelys, Alexandra J. Shay, Rachel T. Nicholson, Noopur Raje, MD, Fredric I. Preffer, PhD, Timothy A. Graubert, MD, Marcela V. Maus, MD PhD

Blood (2017) 130 (Supplement 1): 5363.

https://doi.org/10.1182/blood.V130.Suppl_1.5363.5363

Published: 2017

Journal Articles

Spliceosomal Mutations Induce R Loop-Associated ATR Signaling

Wan Yee Leong, PhD, Hai Dang Nguyen, PhD, Weiling Li, PhD, Matthew J. Walter, MD, Lee Zou, PhD, Timothy A. Graubert, MD

Blood (2017) 130 (Supplement 1): 116.

https://doi.org/10.1182/blood.V130.Suppl_1.116.116

Published: 2017

Journal Articles

Cellular Stressors Contribute to the Expansion of Multiple Hematopoietic Clones of Varying Leukemic Potential

Blood (2017) 130 (Supplement 1): 469.

https://doi.org/10.1182/blood.V130.Suppl_1.469.469

Published: 2017

Journal Articles

Preclinical Rationale for the Use of Regorafenib in Myeloid Malignancies

Gabriela S. Hobbs, MD, Andrew M. Brunner, MD, Timothy A. Graubert, MD, Cyril H Benes, Gabriel Daniel Duda, DMD, PhD, Yi-Bin Chen, MD

Blood (2017) 130 (Supplement 1): 2643.

https://doi.org/10.1182/blood.V130.Suppl_1.2643.2643

Published: 2017

Journal Articles

Dynamic Changes in MDS Clonal Architecture Following Allogeneic Stem Cell Transplant

Meagan A. Jacoby, MD PhD, Eric J. Duncavage, MD, Gue Su Chang, PhD, Christopher A. Miller, PhD, Jin Shao, Kevin Elliott, Robert S. Fulton, PhD, Catrina Fronick, Michelle O'Laughlin, Daniel C. Link, MD, John F DiPersio, MD PhD, Peter Westervelt, MD PhD, Timothy J. Ley, MD, Timothy A. Graubert, MD, Matthew J. Walter, MD, Richard K Wilson, PhD

Blood (2016) 128 (22): 5506.

https://doi.org/10.1182/blood.V128.22.5506.5506

Published: 2016

Journal Articles

Rare Pre-Existing MDS Subclones Contribute to Secondary AML Progression

Eric J. Duncavage, MD, Meagan A. Jacoby, MD PhD, Chris Miller, PhD, Gue Su Chang, PhD, Jin Shao, Kevin Elliot, Catrina Fronick, Michelle O'Laughlin, Robert Fulton, PhD, Richard K Wilson, PhD, Timothy A. Graubert, MD, Matthew J. Walter, MD

Blood (2016) 128 (22): 959.

https://doi.org/10.1182/blood.V128.22.959.959

Published: 2016

Journal Articles

Clinical Implications of Spliceosome Mutations: Epidemiology, Clonal Hematopoiesis, and Potential Therapeutic Strategies

Matthew J. Walter, MD, Timothy A. Graubert, MD

Blood (2016) 128 (22): SCI-19.

https://doi.org/10.1182/blood.V128.22.SCI-19.SCI-19

Published: 2016

Journal Articles

Somatic Mutations in MDS Patients Are Associated with Clinical Features and Predict Prognosis Independent of the IPSS-R: Analysis of Combined Datasets from the International Working Group for Prognosis in MDS-Molecular Committee

Blood (2015) 126 (23): 907.

https://doi.org/10.1182/blood.V126.23.907.907

Published: 2015

Journal Articles

Preclinical Activity of Splicing Modulators in U2AF1 Mutant MDS/AML

Cara Lunn Shirai, PhD, Manorama Tripathi, PhD, James N Ley, Matthew Ndonwi, PhD, Brian S White, PhD, Roberto Tapia, Borja Saez, PhD, Amy Bertino, PhD, Jin Shao, Sanghyun Kim, Thomas R Webb, PhD, Timothy A. Graubert, MD, Matthew J. Walter, MD

Blood (2015) 126 (23): 1653.

https://doi.org/10.1182/blood.V126.23.1653.1653

Published: 2015

Journal Articles

Dynamic Changes in the Clonal Structure of MDS and AML in Response to Epigenetic Therapy

Blood (2015) 126 (23): 610.

https://doi.org/10.1182/blood.V126.23.610.610

Published: 2015

Journal Articles

TP53 Mutation Status Divides MDS Patients with Complex Karyotypes into Distinct Prognostic Risk Groups: Analysis of Combined Datasets from the International Working Group for MDS-Molecular Prognosis Committee

Blood (2014) 124 (21): 532.

https://doi.org/10.1182/blood.V124.21.532.532

Published: 2014

Journal Articles

Functional Dissection of Chromosome 7q Loss and Haploinsufficient Gene Discovery Using iPSC Models of MDS

Andriana Kotini, PhD, Jeffrey J Delrow, PhD, Timothy A. Graubert, MD, Stephen Nimer, MD, Eirini P Papapetrou, MD PhD

Blood (2014) 124 (21): 524.

https://doi.org/10.1182/blood.V124.21.524.524

Published: 2014

Journal Articles

Prognostic Understanding, Quality of Life, and Mood in Patients Undergoing Hematopoietic Stem Cell Transplantation

Areej El-Jawahri, MD, Lara Traeger, PhD, Kailyn Kuzmuk, B.A., Justin Eusebio, B.S., Harry Vandusen, B.S., Jennifer Shin, MD, Emily Gallagher, RN, Joseph Greer, PhD, William Pirl, MD, Vicki Jackson, MD, Karen K. Ballen, MD, Thomas R. Spitzer, MD, Timothy A. Graubert, MD, Steven L. McAfee, MD, Bimalangshu R. Dey, MD PhD, Yi-Bin Chen, MD, Jennifer S. Temel, MD

Blood (2014) 124 (21): 1296.

https://doi.org/10.1182/blood.V124.21.1296.1296

Published: 2014

Journal Articles

A Phase I Study of the Aurora a Kinase Inhibitor Alisertib in Combination with 7+3 Induction Chemotherapy in Patients with Acute Myeloid Leukemia

Amir T. Fathi, MD, Seth A. Wander, MD PhD, Traci M. Blonquist, Karen K. Ballen, MD, Eyal C. Attar, MD, Steven L. McAfee, MD, Yi-Bin Chen, MD, Timothy A. Graubert, MD, Andrew M. Brunner, MD, Christelle Joseph, Ashley M. Perry, Meghan Burke, Regina Silver, Aura Y. Ramos, Christine Connolly, Donna S. Neuberg, ScD, Philip C. Amrein, MD

Blood (2014) 124 (21): 119.

https://doi.org/10.1182/blood.V124.21.119.119

Published: 2014

NARROW

Phase I Study of Ixazomib Added to Chemotherapy in the Treatment of Acute Lymphoblastic Leukemia in Older Adults

Redirecting T-Cells Against AML in a Multidimensional Targeting Space Using T-Cell Engaging Antibody Circuits (TEAC)

Potential Barriers to Clinical Trials of New Therapeutics for Myelodysplastic Syndromes: Wide Variation in Risk Definitions and Trial Enrollment Criteria

Clinical Outcomes Following Frontline Chemotherapy for Patients with Myeloid Malignancies Harboring Splicing Factor Mutations

Single-Cell RNA-Seq Reveals AML Cellular Hierarchies Relevant to Clinical Outcomes and Immunity

Phase II Clinical Trial of Alisertib, an Aurora a Kinase Inhibitor, in Combination with Induction Chemotherapy in High-Risk, Untreated Patients with Acute Myeloid Leukemia

Expression of B Cell Maturation Antigen (BCMA) and Transmembrane Activator and Caml Interactor (TACI) Are Correlated and Can be Targeted at Multiple Points during the Course of Multiple Myeloma

Spliceosomal Mutations Induce R Loop-Associated ATR Signaling

Cellular Stressors Contribute to the Expansion of Multiple Hematopoietic Clones of Varying Leukemic Potential

Preclinical Rationale for the Use of Regorafenib in Myeloid Malignancies

Dynamic Changes in MDS Clonal Architecture Following Allogeneic Stem Cell Transplant

Rare Pre-Existing MDS Subclones Contribute to Secondary AML Progression

Clinical Implications of Spliceosome Mutations: Epidemiology, Clonal Hematopoiesis, and Potential Therapeutic Strategies

Somatic Mutations in MDS Patients Are Associated with Clinical Features and Predict Prognosis Independent of the IPSS-R: Analysis of Combined Datasets from the International Working Group for Prognosis in MDS-Molecular Committee

Preclinical Activity of Splicing Modulators in U2AF1 Mutant MDS/AML

Dynamic Changes in the Clonal Structure of MDS and AML in Response to Epigenetic Therapy

TP53 Mutation Status Divides MDS Patients with Complex Karyotypes into Distinct Prognostic Risk Groups: Analysis of Combined Datasets from the International Working Group for MDS-Molecular Prognosis Committee

Functional Dissection of Chromosome 7q Loss and Haploinsufficient Gene Discovery Using iPSC Models of MDS

Prognostic Understanding, Quality of Life, and Mood in Patients Undergoing Hematopoietic Stem Cell Transplantation

A Phase I Study of the Aurora a Kinase Inhibitor Alisertib in Combination with 7+3 Induction Chemotherapy in Patients with Acute Myeloid Leukemia

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American Society of Hematology

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American Society of Hematology

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