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Journal Articles

Expression and Immunomodulatory Function of RANKL in Leukemia

Benjamin J Schmiedel, Tina Baessler, Miyuki Azuma, Lothar Kanz, MD, Helmut R. Salih, MD

Blood (2011) 118 (21): 245.

https://doi.org/10.1182/blood.V118.21.245.245

Published: 2011

Journal Articles

4-1BB Ligand Mediates a “Vicious Cycle” of Immune Evasion Upon Reciprocal Interaction of Chronic Lymphocytic Leukemia and NK Cells

Corina Buechele, Tina Baessler, Benjamin J Schmiedel, Lothar Kanz, MD, Helmut R. Salih, MD

Blood (2010) 116 (21): 2416.

https://doi.org/10.1182/blood.V116.21.2416.2416

Published: 2010

Journal Articles

NKG2D and Its Ligands In Leukemia: Comprehensive Analysis of Expression, Release and Modulation of NK Cell Reactivity.

Julia Hilpert, Maria Zeiser, Lothar Kanz, MD, Tina Baessler, Alexander Steinle, PhD, Helmut R. Salih, MD

Blood (2010) 116 (21): 1686.

https://doi.org/10.1182/blood.V116.21.1686.1686

Published: 2010

Journal Articles

RANKL Expressed by Acute Myeloid Leukemia Cells Impairs NK Cell-Mediated Immune Surveillance

Benjamin J Schmiedel, Constantin M Wende, Tina Baessler, Carolin Scheible, Stefan Wirths, Miyuki Azuma, Pascal Schneider, Ludger Grosse-Hovest, Lothar Kanz, Helmut R Salih

Blood (2010) 116 (21): 2164.

https://doi.org/10.1182/blood.V116.21.2164.2164

Published: 2010

Journal Articles

Generation, Functional Characterization and Clinical Application of a Novel Fc-Optimized Anti-FLT3 Antibody for the Treatment of Acute Myeloid Leukemia

Helmut R. Salih, MD, Tina Baessler, Martin Hofmann, Ludger Grosse-Hovest, Maximilian Bamberg, Steffen Aulwurm, Hans-Joerg Buehring, Lothar Kanz, MD, Gundram Jung

Blood (2010) 116 (21): 2187.

https://doi.org/10.1182/blood.V116.21.2187.2187

Published: 2010

Journal Articles

Fc-Engineered RANK-Fc Fusion Proteins for Neutralization of Soluble RANKL and Induction of Antibody-Dependent Cellular Cytotoxicity (ADCC) Against Multiple Myeloma

Benjamin J Schmiedel, Carolin Scheible, Tina Baessler, Constantin M Wende, Stefan Wirths, Miyuki Azuma, Pascal Schneider, Ludger Grosse-Hovest, Lothar Kanz, Helmut R Salih

Blood (2010) 116 (21): 3039.

https://doi.org/10.1182/blood.V116.21.3039.3039

Published: 2010

Journal Articles

CD137 ligand mediates opposite effects in human and mouse NK cells and impairs NK-cell reactivity against human acute myeloid leukemia cells

Tina Baessler, Jean Enno Charton, Benjamin Joachim Schmiedel, Frank Grünebach, Matthias Krusch, Alexander Wacker, Hans-Georg Rammensee, Helmut Rainer Salih

Blood (2010) 115 (15): 3058–3069.

https://doi.org/10.1182/blood-2009-06-227934

Published: 2010

Journal Articles

Consequences of 4-1BB-4-1BB Ligand Interaction for NK Cell Anti-Tumor Immunity: Opposite Effects of Seemingly Analogue Molecules in Mice and Men.

Tina Baessler, Jean E Charton, Corina Buechele, Benjamin J Schmiedel, Frank Gruenebach, Matthias Krusch, MD, Alexander Wacker, Lothar Kanz, MD, Helmut R Salih, MD

Blood (2009) 114 (22): 279.

https://doi.org/10.1182/blood.V114.22.279.279

Published: 2009

Journal Articles

A Fc-Engineered RANK-Fc Fusion Protein Neutralizes Soluble RANK Ligand and Targets Malignant Hematopoietic Cells for NK Cell Reactivity.

Benjamin J Schmiedel, Tina Baessler, Carolin Scheible, Constantin M Wende, Miyuki Azuma, Pascal Schneider, Lothar Kanz, MD, Ludger Grosse-Hovest, Helmut R Salih, MD

Blood (2009) 114 (22): 411.

https://doi.org/10.1182/blood.V114.22.411.411

Published: 2009

Journal Articles

Glucocorticoid-Induced TNFR-Related Protein (GITR) Ligand Mediates Tumor Immunoediting in Chronic Lymphocytic Leukemia and Impairs Direct and Rituximab-Induced NK Cell Anti-Leukemia Reactivity.

Corina Buechele, Tina Baessler, Benjamin J Schmiedel, Lothar Kanz, MD, Helmut R Salih, MD

Blood (2009) 114 (22): 4403.

https://doi.org/10.1182/blood.V114.22.4403.4403

Published: 2009

Journal Articles

The Role of CD137 and Its Ligand in Chronic Lymphocytic Leukemia (CLL)

Tina Baessler, Corina Buechele, Matthias Krusch, Benjamin J Schmiedel, Lothar Kanz, Helmut R Salih

Blood (2008) 112 (11): 3130.

https://doi.org/10.1182/blood.V112.11.3130.3130

Published: 2008

Journal Articles

The Role of Activation-Induced C-Type Lectin (AICL) in NK Cell Reactivity against Acute Leukemia

Tina Baessler, Sabrina Kuttfruff, Matthias Krusch, Lothar Kanz, Alexander Steinle, Helmut R Salih

Blood (2008) 112 (11): 2517.

https://doi.org/10.1182/blood.V112.11.2517.2517

Published: 2008

Journal Articles

NK Cell Anti-Tumor Immune Responses Are Impaired by Sorafenib but Not by Sunitinib

Matthias Krusch, MD, Manuela Schlicke, Julia Salih, Tina Baessler, Lothar Kanz, MD, Helmut Salih, MD

Blood (2008) 112 (11): 2632.

https://doi.org/10.1182/blood.V112.11.2632.2632

Published: 2008

Journal Articles

Neutralization of tumor-derived soluble Glucocorticoid-Induced TNFR-Related Protein ligand increases NK cell anti-tumor reactivity

Katrin M. Baltz, Matthias Krusch, Tina Baessler, Benjamin J. Schmiedel, Anita Bringmann, Peter Brossart, Helmut R. Salih

Blood (2008) 112 (9): 3735–3743.

https://doi.org/10.1182/blood-2008-03-143016

Published: 2008

Includes: Supplemental data

Journal Articles

The Kinase Inhibitors Sunitinib (Sutent®) and Sorafenib (Nexavar®) Differentially Affect Reactivity of NK Cells Against Renal Cell Cancer.

Schlicke Manuela, Krusch Matthias, MD, Tina Baessler, Lothar Kanz, MD, Helmut R. Salih, MD

Blood (2007) 110 (11): 4182.

https://doi.org/10.1182/blood.V110.11.4182.4182

Published: 2007

Journal Articles

Neutralization of Tumor-Derived Soluble Glucocorticoid-Induced TNF-Related Protein (GITR) Ligand Present in Cancer Patient Sera Increases Anti-Tumor Reactivity of NK Cells.

Katrin M. Baltz, Matthias Krusch, MD, Tina Baessler, Anita Bringmann, Lothar Kanz, MD, Peter Brossart, MD, Helmut R. Salih, MD

Blood (2007) 110 (11): 314.

https://doi.org/10.1182/blood.V110.11.314.314

Published: 2007

Journal Articles

Toll-Like Receptor-Induced Expression of the NKG2D Ligand MICA on Monocytes Modulates Their Interaction with NK Cells.

Mercedes Kloss, Patrice Decker, PhD, Matthias Krusch, MD, Katrin M. Baltz, Tina Baessler, Lothar Kanz, MD, Alexander Steinle, PhD, Helmut R. Salih, MD

Blood (2007) 110 (11): 2415.

https://doi.org/10.1182/blood.V110.11.2415.2415

Published: 2007

Journal Articles

Role of Glucocorticoid-Induced TNF-Related Protein (GITR) Ligand in the Interaction of Acute Myeloid Leukemia with NK Cells.

Matthias Krusch, MD, Katrin M. Baltz, Tina Baessler, Lothar Kanz, MD, Helmut R. Salih, MD

Blood (2007) 110 (11): 18.

https://doi.org/10.1182/blood.V110.11.18.18

Published: 2007

Journal Articles

Role of CD137/4-1BB and Its Ligand in the NK Cell Mediated Immune Surveillance of Acute Myeloid Leukemia.

Tina Baessler, Matthias Krusch, MD, Katrin M. Baltz, Benjamin J. Schmiedel, Helga M. Schmetzer, PhD, Lothar Kanz, MD, Helmut R. Salih, MD

Blood (2007) 110 (11): 880.

https://doi.org/10.1182/blood.V110.11.880.880

Published: 2007

Journal Articles

Expression of Glucocorticoid-Induced TNF Receptor Ligand on Acute Myeloid Leukemia Cells Mediates the Release of Immunosuppressive Cytokines and Impairs NK Cell-Mediated Immune Surveillance.

Matthias Krusch, MD, Katrin M. Baltz, Tina Baessler, Mercedes Kloss, Ingrid Kumbier, Andrea Peterfi, Lothar Kanz, MD, Helmut R. Salih, MD

Blood (2006) 108 (11): 1941.

https://doi.org/10.1182/blood.V108.11.1941.1941

Published: 2006

NARROW

Expression and Immunomodulatory Function of RANKL in Leukemia

4-1BB Ligand Mediates a “Vicious Cycle” of Immune Evasion Upon Reciprocal Interaction of Chronic Lymphocytic Leukemia and NK Cells

NKG2D and Its Ligands In Leukemia: Comprehensive Analysis of Expression, Release and Modulation of NK Cell Reactivity.

RANKL Expressed by Acute Myeloid Leukemia Cells Impairs NK Cell-Mediated Immune Surveillance

Generation, Functional Characterization and Clinical Application of a Novel Fc-Optimized Anti-FLT3 Antibody for the Treatment of Acute Myeloid Leukemia

Fc-Engineered RANK-Fc Fusion Proteins for Neutralization of Soluble RANKL and Induction of Antibody-Dependent Cellular Cytotoxicity (ADCC) Against Multiple Myeloma

CD137 ligand mediates opposite effects in human and mouse NK cells and impairs NK-cell reactivity against human acute myeloid leukemia cells

Consequences of 4-1BB-4-1BB Ligand Interaction for NK Cell Anti-Tumor Immunity: Opposite Effects of Seemingly Analogue Molecules in Mice and Men.

A Fc-Engineered RANK-Fc Fusion Protein Neutralizes Soluble RANK Ligand and Targets Malignant Hematopoietic Cells for NK Cell Reactivity.

Glucocorticoid-Induced TNFR-Related Protein (GITR) Ligand Mediates Tumor Immunoediting in Chronic Lymphocytic Leukemia and Impairs Direct and Rituximab-Induced NK Cell Anti-Leukemia Reactivity.

The Role of CD137 and Its Ligand in Chronic Lymphocytic Leukemia (CLL)

The Role of Activation-Induced C-Type Lectin (AICL) in NK Cell Reactivity against Acute Leukemia

NK Cell Anti-Tumor Immune Responses Are Impaired by Sorafenib but Not by Sunitinib

Neutralization of tumor-derived soluble Glucocorticoid-Induced TNFR-Related Protein ligand increases NK cell anti-tumor reactivity

The Kinase Inhibitors Sunitinib (Sutent®) and Sorafenib (Nexavar®) Differentially Affect Reactivity of NK Cells Against Renal Cell Cancer.

Neutralization of Tumor-Derived Soluble Glucocorticoid-Induced TNF-Related Protein (GITR) Ligand Present in Cancer Patient Sera Increases Anti-Tumor Reactivity of NK Cells.

Toll-Like Receptor-Induced Expression of the NKG2D Ligand MICA on Monocytes Modulates Their Interaction with NK Cells.

Role of Glucocorticoid-Induced TNF-Related Protein (GITR) Ligand in the Interaction of Acute Myeloid Leukemia with NK Cells.

Role of CD137/4-1BB and Its Ligand in the NK Cell Mediated Immune Surveillance of Acute Myeloid Leukemia.

Expression of Glucocorticoid-Induced TNF Receptor Ligand on Acute Myeloid Leukemia Cells Mediates the Release of Immunosuppressive Cytokines and Impairs NK Cell-Mediated Immune Surveillance.

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American Society of Hematology

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ASH Publications

American Society of Hematology

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