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Journal Articles

Minimal residual disease negativity using deep sequencing is a major prognostic factor in multiple myeloma

Clinical Trials & Observations
Aurore Perrot, Valerie Lauwers-Cances, Jill Corre, Nelly Robillard, Cyrille Hulin, Marie-Lorraine Chretien, Thomas Dejoie, Sabrina Maheo, Anne-Marie Stoppa, Brigitte Pegourie, Lionel Karlin, Laurent Garderet, Bertrand Arnulf, Chantal Doyen, Nathalie Meuleman, Bruno Royer, Jean-Richard Eveillard, Lotfi Benboubker, Mamoun Dib, Olivier Decaux, Arnaud Jaccard, Karim Belhadj, Sabine Brechignac, Brigitte Kolb, Cecile Fohrer, Mohamad Mohty, Margaret Macro, Paul G. Richardson, Victoria Carlton, Martin Moorhead, Tom Willis, Malek Faham, Kenneth C. Anderson, Jean-Luc Harousseau, Xavier Leleu, Thierry Facon, Philippe Moreau, Michel Attal, Hervé Avet-Loiseau, Nikhil Munshi
Journal: Blood
Blood (2018) 132 (23): 2456–2464.
https://doi.org/10.1182/blood-2018-06-858613
Published: 2018
Includes: Supplemental data
Journal Articles

Next Generation Sequencing (NGS) Based Minimal Residual Disease (MRD) Testing Is Highly Predictive of Overall and Progression Free Survival in the Total Therapy Trials and Shows Different Prognostic Implications in High Vs Standard Risk Multiple Myeloma

Carolina Schinke, MD, Shayu Deshpande, PhD, Hongwei Wang, Victoria Carlton, PhD, Katherine A. Kong, PhD, Martin Moorhead, PhD, Tom Willis, Purvi Patel, Sharmilan Thanendrarajan, MD, Meera Mohan, MD, Pankaj Mathur, MD, Sandra Susanibar, MD, Shadiqul Hoque, MD, Muthukumar Radhakrishnan, MD, Ruslana Tytarenko, Owen W Stephens, Leo Rasche, MD, Frits van Rhee, MD PhD, Maurizio Zangari, MD, Nathan Petty, MS, Daisy V. Alapat, MD, Sarah K. Johnson, PhD, Joshua Epstein, DSc, Bart Barlogie, MD PhD, Faith E Davies, MD, Antje Hoering, PhD, Niels Weinhold, PhD, Gareth J Morgan, MD PhD
Journal: Blood
Blood (2016) 128 (22): 2064.
https://doi.org/10.1182/blood.V128.22.2064.2064
Published: 2016
Journal Articles

DNA Sequencing-Based Monitoring Of Serum Predicts Clinical Relapse Before CT Imaging in Diffuse Large B-Cell Lymphoma

Mark Roschewski, MD, Stefania Pittaluga, MD, Kieron Dunleavy, MD, Katherine Kong, MS, Margaret Shovlin, RN, Elaine S. Jaffe, MD, Louis M. Staudt, MD, PhD, Jianbiao Zheng, PhD, Tom Willis, PhD, Malek Faham, MD, PhD, Wyndham H Wilson, MD, PhD
Journal: Blood
Blood (2013) 122 (21): 1767.
https://doi.org/10.1182/blood.V122.21.1767.1767
Published: 2013
Journal Articles

Minimal Residual Disease Quantification in Acute Lymphoblastic Leukemia Using High-Throughput Sequencing of Multiple Immunoreceptor Genes Predicts Relapse and Survival After Allogeneic Hematopoietic Cell Transplantation.

Aaron C. Logan, MD, PhD, Nikita Vashi, BS, Malek Faham, MD, PhD, Victoria Carlton, PhD, Ismael Buno, PhD, Jianbiao Zheng, PhD, Martin Moorhead, PhD, Mark Klinger, PhD, Tom Willis, PhD, Bing Zhang, MD, Amna Waqar, BS, James L. Zehnder, David B Miklos, MD, PhD
Journal: Blood
Blood (2012) 120 (21): 2512.
https://doi.org/10.1182/blood.V120.21.2512.2512
Published: 2012
Journal Articles

Highly Sensitive Detection of Minimal Residual Disease in Acute Lymphoblastic Leukemia Using Next-Generation Sequencing of Immunoglobulin Heavy Chain Variable Region

Malek Faham, MD, PhD, Tom Willis, PhD, Martin Moorhead, PhD, Victoria Carlton, PhD, Jianbiao Zheng, PhD, Dario Campana, MD, PhD
Journal: Blood
Blood (2011) 118 (21): 2540.
https://doi.org/10.1182/blood.V118.21.2540.2540
Published: 2011
Journal Articles

High-Throughput Immunoglobulin Gene Sequencing Quantifies Minimal Residual Disease in CLL with 10e-6 Sensitivity and Strongly Predicts Relapse After Allogeneic Hematopoietic Cell Transplantation

Aaron C. Logan, MD, PhD, Malek Faham, MD, PhD, Victoria Carlton, PhD, Jianbiao Zheng, PhD, Martin Moorhead, PhD, Tom Willis, PhD, Carol D. Jones, Melody B. Zhang, PhD, Amna N. Waqar, James L. Zehnder, MD, David B. Miklos, MD, PhD
Journal: Blood
Blood (2011) 118 (21): 2542.
https://doi.org/10.1182/blood.V118.21.2542.2542
Published: 2011
Journal Articles

Next-Generation Sequencing of Immunoglobulin Heavy Chain Variable Region in Diagnostic Samples of Pediatric Acute Lymphoblastic Leukemia Identifies Hundreds of Clonal Subpopulations with Multiple Immunophenotypes

Charles Gawad, MD, Malek Faham, MD, PhD, Tom Willis, PhD, Martin Moorhead, PhD, Victoria Carlton, PhD, Jianbiao Zheng, PhD, Mark Klinger, Gary V Dahl, MD, Norman J. Lacayo, MD
Journal: Blood
Blood (2011) 118 (21): 1436.
https://doi.org/10.1182/blood.V118.21.1436.1436
Published: 2011
Journal Articles

Massively Parallel Immunoglobulin Gene Sequencing Provides Ultra-Sensitive Minimal Residual Disease Detection and Predicts Post-Transplant Relapse in Acute Lymphoblastic Leukemia by Three to Six Months,

Aaron C. Logan, MD, PhD, Nikita Vashi, BS, Malek Faham, MD, PhD, Victoria Carlton, PhD, Ismael Buno, MD, Jianbiao Zheng, PhD, Martin Moorhead, PhD, Mark Klinger, PhD, Tom Willis, PhD, Melody B. Zhang, PhD, Amna Waqar, James L. Zehnder, MD, David B. Miklos, MD, PhD
Journal: Blood
Blood (2011) 118 (21): 4104.
https://doi.org/10.1182/blood.V118.21.4104.4104
Published: 2011