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Journal Articles

Examination of Phosphoprotein Targets in Timed Samples from Patients with RAS -Mutated AML during Concurrent Treatment with Alpelisib and Binimetinib on the Phase Ib Clinical Trial CMEK162X2109

Kira Gritsman, MD PhD, Robert P. Hasserjian, MD, Taneisha Sinclair, David M. Weinstock, MD, Britta Will, PhD, Ulrich Steidl, MD PhD, Karen K. Ballen, MD, Amir T. Fathi, MD, Amit Verma, MD, Dejan Juric, MD, Philip C. Amrein, MD

Blood (2016) 128 (22): 2749.

https://doi.org/10.1182/blood.V128.22.2749.2749

Published: 2016

Journal Articles

Hispanic Ethnicity Is Associated with Younger Age at Presentation and Worse Survival in AML

Karine Antonovna Darbinyan, MD, Daniel Helbig, MDcal Student, Junaid Saleh Esa, College student, Anjali Budhathoki, MD, Swati Goel, MD, Aditi Shastri, MD, Murali Janakiram, MD, Noah Kornblum, MD, Olga Derman, MD, Kira Gritsman, MD PhD, Ulrich Steidl, MD PhD, Amit Verma, MD, Ira Braunschweig, MD, Ioannis Mantzaris, MD

Blood (2016) 128 (22): 3600.

https://doi.org/10.1182/blood.V128.22.3600.3600

Published: 2016

Journal Articles

CITED2 Cooperates with Low PU.1 and DNMT3A to Maintain Self-Renewal in Hematopoietic Stem Cells

Hein Schepers, PhD, Patrick Korthuis, MSc, Marjan Geugien, MSc, Jennifer Jaques, MSc, Tihomira I. Todorova, MSc, Ulrich Steidl, MD PhD, Jan Jacob Schuringa, PhD, Edo Vellenga, MD PhD

Blood (2015) 126 (23): 309.

https://doi.org/10.1182/blood.V126.23.309.309

Published: 2015

Journal Articles

Interleukin-1 Drives Precocious Myeloid Differentiation of Hematopoietic Stem Cells at the Expense of Self-Renewal

Eric Martin Pietras, PhD, Cristina Mirantes-Barbeito, PhD, Sarah Fong, Dirk Loffler, PhD, Larisa Vladimirovna Kovtonyuk, Ranjani Lakshminarashimhan, Chih Peng Chin, Jose-Marc Techner, Britta Will, PhD, Claus Nerlov, PhD, Ulrich Steidl, MD PhD, Markus Manz, MD, Timm Schroeder, PhD, Emmanuelle Passegue, PhD

Blood (2015) 126 (23): 778.

https://doi.org/10.1182/blood.V126.23.778.778

Published: 2015

Journal Articles

PAK1 Is a Therapeutic Target in Acute Myeloid Leukemia and Myelodysplastic Syndrome

Robert Stanley, Ashley Pandolfi, M.Sc., Amit Verma, MD, Ulrich Steidl, MD PhD, Jonathan Chernoff, MD PhD, Yiting Yu, PhD, Jacqueline Boultwood

Blood (2014) 124 (21): 4614.

https://doi.org/10.1182/blood.V124.21.4614.4614

Published: 2014

Journal Articles

Efficacy of Dual Inhibition of p38 Mitogen Activated Protein Kinase (MAPK) and Tie-2 Kinase in Myelodysplastic Syndromes (MDS) and Acute Myeloid Leukemia (AML)

Blood (2014) 124 (21): 4628.

https://doi.org/10.1182/blood.V124.21.4628.4628

Published: 2014

Journal Articles

Myelodysplastic Syndrome Marrow Stroma Shows Widespread Aberrant Hypermethylation That Is Abrogated By Treatment with Dnmt Inhibitors

Tushar D Bhagat, PhD, Matthias Bartenstein, MD, Yiting Yu, PhD, A. Mario Q. Marcondes, MD PhD, Britta Will, PhD, Orsolya Giricz, PhD, Davendra P. Sohal, MD MPH, Ioannis Mantzaris, MD, Amittha Wickrema, PhD, Christine Mcmahon, MD, Yeung Cecilia, MD, John Greally, MB, PhD, Siddhartha Mukherjee, MD PhD, Ulrich Steidl, MD PhD, H. Joachim Deeg, MD, Amit Verma, MD

Blood (2014) 124 (21): 4379.

https://doi.org/10.1182/blood.V124.21.4379.4379

Published: 2014

Journal Articles

Molecular and Functional Characterization Of The Novel Protein-Coding Gene Tihl (Translocated in Hodgkin’s Lymphoma) in Hematopoiesis

Ujunwa Cynthia Okoye-Okafor, M.Sc., Laura Barreyro, M.Sc., Heng Rui Wang, M.Sc., Boris Bartholdy, Ph.D., Britta Will, PhD, Tihomira I Todorova, B.A., Swathi-Rao Narayanagari, M.Sc., Mario Pujato, M.Sc., Masahiro Kawahara, MD, PhD, Bruce W. Woolcock, MSc, Randy D. Gascoyne, MD, Christian Steidl, MD, Ulrich Steidl, MD PhD

Blood (2013) 122 (21): 3680.

https://doi.org/10.1182/blood.V122.21.3680.3680

Published: 2013

Journal Articles

H2.0-Like Homeobox (HLX) Causes Pre-Leukemic Myeloid Expansion and Initiates AML In Cooperation With FLT3-ITD

Ashley Pandolfi, M.Sc., Boris Bartholdy, Ph.D., Britta Will, PhD, Robert Stanley, Tihomira I Todorova, B.A., Christine McMahon, MD, Ulrich Steidl, MD PhD

Blood (2013) 122 (21): 4201.

https://doi.org/10.1182/blood.V122.21.4201.4201

Published: 2013

Journal Articles

Epigenetic Profiling Of Leukemia Stem Cells In a Model Of TET2/FLT3-Mutant AML

Alan H. Shih, MD PhD, Yanwen Jiang, PhD, Kaitlyn Shank, Suveg Pandey, Agnes Viale, PhD, Yongming Sun, PhD, Nicholas Socci, PhD, Alexander Robertson, PhD, Elisa de Stanchina, PhD, Todd Hricik, Franck Rapaport, PhD, Brittany Woods, Luisa Cimmino, PhD, Laura Barreyro, M.Sc., Ulrich Steidl, MD PhD, Iannis Aifantis, PhD, Ari Melnick, MD, Ross L. Levine, MD

Blood (2013) 122 (21): 476.

https://doi.org/10.1182/blood.V122.21.476.476

Published: 2013

Journal Articles

Inhibition Of CXCR2 As a Therapeutic Strategy In AML and MDS

Carolina Schinke, Orsolya Giricz, Shanisha A. K. Gordon, Laura Barreyro, M.Sc., Tushar D. Bhagat, Andrea Pellagatti, Jacqueline Boultwood, Yiting Yu, Ulrich Steidl, MD PhD, Amit Verma

Blood (2013) 122 (21): 484.

https://doi.org/10.1182/blood.V122.21.484.484

Published: 2013

Journal Articles

Identification of a Novel Protein-Coding Gene ( TIHL) and Its Functional Relevance in Myeloid Cells.

Ujunwa Cynthia Okoye-Okafor, M.Sc., Boris Bartholdy, Ph.D., Bruce Woolcock, M.Sc., Masahiro Kawahara, MD, PhD, Tihomira I Todorova, B.A., Randy D. Gascoyne, MD, Christian Steidl, MD, Ulrich Steidl, MD, PhD

Blood (2012) 120 (21): 2333.

https://doi.org/10.1182/blood.V120.21.2333.2333

Published: 2012

Journal Articles

Metastasis Suppressor 1 Is Downregulated in CML Stem Cells and Overexpression Impairs Early Leukemic Cell Propagation.

Mirle Schemionek, PhD, Ulrich Steidl, MD, PhD, Albrecht Schwab, MD, Daniel G Tenen, MD, Copland Mhairi, PhD, Tessa L. Holyoake, PhD, FRCP, FRCPath, Christian Preisinger, PhD, Carsten Mueller-Tidow, MD, Tim H Brümmendorf, Steffen Koschmieder, MD

Blood (2012) 120 (21): 2776.

https://doi.org/10.1182/blood.V120.21.2776.2776

Published: 2012

Journal Articles

Parallel Transcriptional Analysis of Multiple Stem and Progenitor Populations Identifies Novel Commonly Dysregulated and Functionally Relevant Targets in AML

Blood (2012) 120 (21): 1875.

https://doi.org/10.1182/blood.V120.21.1875.1875

Published: 2012

Journal Articles

PU.1 and p53 Double Mutant Mice Develop Aggressive AML with Dysplastic Features

Petra Vlckova, MSc., Libor Stanek, MSc., Pavel Burda, PhD, Karin Vargova, MSc., Filipp Savvulidi, Martina Kapalova, MSc., Ulrich Steidl, MD, PhD, Tomas Stopka, MD, PhD

Blood (2012) 120 (21): 769.

https://doi.org/10.1182/blood.V120.21.769.769

Published: 2012

Journal Articles

H2.0-Like Homeobox (HLX) Induces Unlimited Clonogenicity, Blocks Differentiation, and Cooperates with FLT3-ITD in the Induction of Acute Myeloid Leukemia

Ashley Pandolfi, M.Sc., Boris Bartholdy, Ph.D., Masahiro Kawahara, MD, Laura Barreyro, Britta Will, PhD, Robert Stanley, Roth Michael, MD, Ujunwa Cynthia Okoye-Okafor, M.Sc., Tihomira I Todorova, B.A., Maria E. Figueroa, MD, Ari Melnick, MD, Constantine S. Mitsiades, MD, PhD, Ulrich Steidl, MD, PhD

Blood (2012) 120 (21): 651.

https://doi.org/10.1182/blood.V120.21.651.651

Published: 2012

Journal Articles

Neuropeptides Orexin A and B Are Funktionally Aktive in CD34+ Hematopoietic Stem and Progenitor Cells.

Ron-Patrick Cadeddu, Akos G. Czibere, MD, Sebastian Büst, Johannes C Fischer, Ulrich Steidl, MD, PhD, Ralf Kronenwett, Guido Kobbe, MD, Rainer Haas, Ingmar Bruns, MD, PhD

Blood (2009) 114 (22): 4593.

https://doi.org/10.1182/blood.V114.22.4593.4593

Published: 2009

Journal Articles

Dysregulation of TGF-Beta Stimulated Smad Signaling Is Seen in Myelodysplasia and Points to the Potential Therapeutic Efficacy of TGF-Beta Receptor I Kinase Inhibition in Low Grade Disease.

Blood (2009) 114 (22): 737.

https://doi.org/10.1182/blood.V114.22.737.737

Published: 2009

Journal Articles

Mtss1 Suppresses BCR-ABL Induced Cell Migration and Is Downregulated in CML Stem Cells.

Mirle Schemionek, Shuchi Agrawal, PhD, Martin Stehling, PhD, Daniel G. Tenen, MD, Ashley Hamilton, Tessa Holyoake, MD, PhD, Ulrich Steidl, MD, PhD, Wolfgang E. Berdel, MD, Albrecht Schwab, MD, Carsten Müller-Tidow, MD, Steffen Koschmieder, MD

Blood (2008) 112 (11): 1077.

https://doi.org/10.1182/blood.V112.11.1077.1077

Published: 2008

Journal Articles

Hematopoiesis in Chronic Phase CML emerges from Hematopoietic Stem Cells with a Transcriptional Phenotype Resembling Normal Myeloid Progenitor Cells.

Ingmar Bruns, MD, PhD, Akos Czibere, MD, PhD, Patrick Cadeddu, Frederik Roels, Johannes C Fischer, Sebastian Büst, Daniela Brünnert, Ulrich Steidl, MD, PhD, Benedict Brors, Norbert Gattermann, MD, Ralf Kronenwett, Rainer Haas

Blood (2008) 112 (11): 3365.

https://doi.org/10.1182/blood.V112.11.3365.3365

Published: 2008

NARROW

Examination of Phosphoprotein Targets in Timed Samples from Patients with RAS -Mutated AML during Concurrent Treatment with Alpelisib and Binimetinib on the Phase Ib Clinical Trial CMEK162X2109

Hispanic Ethnicity Is Associated with Younger Age at Presentation and Worse Survival in AML

CITED2 Cooperates with Low PU.1 and DNMT3A to Maintain Self-Renewal in Hematopoietic Stem Cells

Interleukin-1 Drives Precocious Myeloid Differentiation of Hematopoietic Stem Cells at the Expense of Self-Renewal

PAK1 Is a Therapeutic Target in Acute Myeloid Leukemia and Myelodysplastic Syndrome

Efficacy of Dual Inhibition of p38 Mitogen Activated Protein Kinase (MAPK) and Tie-2 Kinase in Myelodysplastic Syndromes (MDS) and Acute Myeloid Leukemia (AML)

Myelodysplastic Syndrome Marrow Stroma Shows Widespread Aberrant Hypermethylation That Is Abrogated By Treatment with Dnmt Inhibitors

Molecular and Functional Characterization Of The Novel Protein-Coding Gene Tihl (Translocated in Hodgkin’s Lymphoma) in Hematopoiesis

H2.0-Like Homeobox (HLX) Causes Pre-Leukemic Myeloid Expansion and Initiates AML In Cooperation With FLT3-ITD

Epigenetic Profiling Of Leukemia Stem Cells In a Model Of TET2/FLT3-Mutant AML

Inhibition Of CXCR2 As a Therapeutic Strategy In AML and MDS

Identification of a Novel Protein-Coding Gene ( TIHL) and Its Functional Relevance in Myeloid Cells.

Metastasis Suppressor 1 Is Downregulated in CML Stem Cells and Overexpression Impairs Early Leukemic Cell Propagation.

Parallel Transcriptional Analysis of Multiple Stem and Progenitor Populations Identifies Novel Commonly Dysregulated and Functionally Relevant Targets in AML

PU.1 and p53 Double Mutant Mice Develop Aggressive AML with Dysplastic Features

H2.0-Like Homeobox (HLX) Induces Unlimited Clonogenicity, Blocks Differentiation, and Cooperates with FLT3-ITD in the Induction of Acute Myeloid Leukemia

Neuropeptides Orexin A and B Are Funktionally Aktive in CD34+ Hematopoietic Stem and Progenitor Cells.

Dysregulation of TGF-Beta Stimulated Smad Signaling Is Seen in Myelodysplasia and Points to the Potential Therapeutic Efficacy of TGF-Beta Receptor I Kinase Inhibition in Low Grade Disease.

Mtss1 Suppresses BCR-ABL Induced Cell Migration and Is Downregulated in CML Stem Cells.

Hematopoiesis in Chronic Phase CML emerges from Hematopoietic Stem Cells with a Transcriptional Phenotype Resembling Normal Myeloid Progenitor Cells.

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American Society of Hematology

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American Society of Hematology

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