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Wolfgang R Sperr, M.D.
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Journal Articles

Imatinib Inhibits SCF-Induced Development Of Human Mast Cells In Vitro and Induces Profound and Selective Mast Cell Deficiency In Patients With Ph+ CML

Sabine Cerny-Reiterer, D.V.M, Anja Rabenhorst, Msc, Ph.D., Gabriele Stefanzl, Msc, Susanne Herndlhofer, Katharina Blatt, MSc, Ph.D., Gregor Hoermann, M.D., Ph.D., Leonhard Muellauer, M.D., Sigrid Baumgartner, M.D., Christine Beham-Schmid, M.D., Wolfgang R Sperr, M.D., Werner Linkesch, M.D., Christine Mannhalter, M.D., Michel Arock, PharmD, Ph.D, Karin Hartmann, M.D., Peter Valent
Journal: Blood
Blood (2013) 122 (21): 3988.
https://doi.org/10.1182/blood.V122.21.3988.3988
Published: 2013
Journal Articles

Bromodomain-Containing Protein 4 (BRD4): A Novel Marker and Drug Target Expressed In Neoplastic Cells In Advanced Mast Cell Neoplasms

Ghaith Wedeh, Emir Hadzijusufovic, DVM, Sabine Cerny-Reiterer, D.V.M, Harald Herrmann, M.D., Katharina Blatt, MSc, Ph.D., Gregor Eisenwort, M.D., Ph.D, Gregor Hoermann, M.D., Ph.D., Wolfgang R Sperr, M.D., Leonhard Müllauer, M.D., Christopher R. Vakoc, M.D., Ph.D., James E Bradner, MD, Hans-Peter Horny, MD, Michael Willmann, D.V.M., Johannes Zuber, MD, Michel Arock, PharmD, Ph.D, Peter Valent
Journal: Blood
Blood (2013) 122 (21): 3747.
https://doi.org/10.1182/blood.V122.21.3747.3747
Published: 2013
Journal Articles

Allogeneic Hematopoietic Cell Transplantation Is Effective In Patients With Advanced Systemic Mastocytosis: A Multicenter Retrospective Analysis

Celalettin Ustun, Andreas Reiter, Bart L Scott, MD, Ryotaro Nakamura, Damaj Gandhi, Sebastian Kreil, Ryan Shanley, William J Hogan, MD, Miguel-Angel Perales, MD, Tsiporah B. Shore, Herrad Baurmann, Robert K Stuart, Bernd Gruhn, Michael Doubek, Jack W Hsu, Eleni Tholouli, Tanja Gromke, Lucy A Godley, Livio Pagano, MD, Andrew Gilman, Eva Maria Wagner, MD, Tor Shwayder, Martin Bornhaeuser, Esperanza B Papadopoulos, M.D., Alexandra Boehm, Gregory M Vercellotti, Maria Theresa Van Lint, Christoph Schmid, Werner Rabitsch, MD, Vinod Pullarkat, MD, A. John Barrett, MD, Olivier Hermine, MD, PhD, Hans Gustaf Hagglund, Wolfgang R Sperr, M.D., Uday R Popat, MD, Steven M. Devine, MD, H. Joachim Deeg, MD, Daniel J. Weisdorf, MD, Cem Akin, Peter Valent
Journal: Blood
Blood (2013) 122 (21): 2145.
https://doi.org/10.1182/blood.V122.21.2145.2145
Published: 2013
Journal Articles

Phenotyping Of Leukemic Stem Cells In Ph+ ALL and Ph- ALL Reveals Unique Profiles Of Markers and Targets In Distinct Disease Variants

Sabine Cerny-Reiterer, D.V.M, Katharina Blatt, MSc, Ph.D., Harald Herrmann, M.D., Gregor Eisenwort, M.D., Ph.D, Susanne Herndlhofer, Heinz Sill, M.D., Werner Rabitsch, MD, Christine Mannhalter, M.D., Alexander Hauswirth, M.D., Wolfgang R Sperr, M.D., Ulrich Jaeger, Peter Valent
Journal: Blood
Blood (2013) 122 (21): 1654.
https://doi.org/10.1182/blood.V122.21.1654.1654
Published: 2013
Journal Articles

Abnormal Expression Of The Major Coxsackie-Adenovirus Receptor CAR On Immature Dysplastic CD105+ Erythroid Progenitor Cells In Patients With MDS and Related Bone Marrow Neoplasms

Sigrid Machherndl-Spandl, MD, Susanne Suessner, Martin Danzer, Johannes Proell, Christian Gabriel, MD, Jeroen Lauf, Gregor Eisenwort, Wolfgang R Sperr, M.D., Peter Valent, Hans-Ulrich Klein, PhD, Marie-Christine Bene, PharmSciD, PhD, Ulrich Germing, MD, Uwe Platzbecker, MD, PhD, Ansgar Weltermann, MD, Otto Zach, PhD, Peter Bettelheim, MD
Journal: Blood
Blood (2013) 122 (21): 2818.
https://doi.org/10.1182/blood.V122.21.2818.2818
Published: 2013
Journal Articles

KIT D816V Mutation Burden Predicts Prognosis and Survival In Patients With Mastocytosis and Correlates With The WHO Type Of The Disease

Gregor Hoermann, M.D., Ph.D., Karoline V. Gleixner, M.D., Graziella E. Dinu, B.Sc., Georg Greiner, Friedrich Wimazal, M.D., Emir Hadzijusufovic, DVM, Gerlinde Mitterbauer, M.D., Christine Mannhalter, Ph.D., Peter Valent, Wolfgang R Sperr, M.D.
Journal: Blood
Blood (2013) 122 (21): 4052.
https://doi.org/10.1182/blood.V122.21.4052.4052
Published: 2013
Journal Articles

The Oncogenic Transcription Factor STAT5 Triggers Aberrant Expression Of CD25 (IL-2RA) In Neoplastic Stem Cells In Ph + CML

Irina Sadovnik, M.Sc., Harald Herrmann, M.D., Sabine Cerny-Reiterer, D.V.M, Wolfgang Warsch, Ph.D., Andrea Hoelbl, Ph.D., Katharina Blatt, MSc, Ph.D., Barbara Peter, D.V.M., Gabriele Stefanzl, Msc, Gregor Hoermann, M.D., Ph.D., Susanne Herndlhofer, Berthold Streubel, M.D., Wolfgang R Sperr, M.D., Christine Mannhalter, Ph.D., Veronika Sexl, MD, Peter Valent
Journal: Blood
Blood (2013) 122 (21): 3979.
https://doi.org/10.1182/blood.V122.21.3979.3979
Published: 2013
Journal Articles

Nilotinib Exerts Direct Pro-Atherogenic and Anti-Angiogenic Effects On Vascular Endothelial Cells: A Potential Explanation For Drug-Induced Vasculopathy In CML

Hadzijusufovic Emir, DVM, Karin Albrecht-Schgoer, PhD, Kilian Huber, PhD, Florian Grebien, PhD, Gregor Eisenwort, MD, PhD, Wilfried Schgoer, MD, PhD, Christoph Kaun, Susanne Herndlhofer, Markus Theurl, PhD, Sabine Cerny-Reiterer, D.V.M., Gregor Hoermann, M.D., Ph.D., Wolfgang R Sperr, M.D., Rix Uwe, PhD, Johann Wojta, PhD, Dominik Wolf, MD, Giulio Superti-Furga, PhD, Rudolf Kirchmair, MD, Peter Valent
Journal: Blood
Blood (2013) 122 (21): 257.
https://doi.org/10.1182/blood.V122.21.257.257
Published: 2013
Journal Articles

Serum Tryptase Is a Strong Predictive Biomarker That Improves Prognostication in Ph+ Chronic Myeloid Leukemia.

Wolfgang R. Sperr, M.D., Thomas Pfeiffer, Michael Kundi, MD, Christian Sillaber, MD, Susanne Herndlhofer, Peter Valent, MD
Journal: Blood
Blood (2012) 120 (21): 2783.
https://doi.org/10.1182/blood.V120.21.2783.2783
Published: 2012
Journal Articles

Expression of the CAMPATH-1 Antigen (CD52) on CD34+/CD38- Progenitor Cells in Patients with 5q- MDS and in a Subset of AML

Katharina Blatt, M.Sc., Harald Herrmann, M.D., Sabine Cerny-Reiterer, D.V.M., Susanne Herndlhofer, Wolfgang R. Sperr, M.D., Peter Valent, M.D.
Journal: Blood
Blood (2011) 118 (21): 1728.
https://doi.org/10.1182/blood.V118.21.1728.1728
Published: 2011
Journal Articles

The Leukemic Stem Cell (LSC) in Ph + CML Is a CD34 + /CD38 − /Lin − Cell That Co-Expresses Dipeptidylpeptidase IV (CD26) and Disrupts LSC-Niche Interactions by Degrading the CXCR4 Ligand SDF-1α

Harald Herrmann, M.D., Irina Sadovnik, M.Sc., Sabine Cerny-Reiterer, D.V.M., Katharina Blatt, M.Sc., Viviane Ghanim, M.D., Susanne Herndlhofer, Gregor Hoermann, M.D., Thomas Rülicke, D.V.M., Michael Willmann, D.V.M., Gerlinde Mitterbauer-Hohendanner, M.D., Matthias Mayerhofer, M.D., Wolfgang R. Sperr, M.D., Peter Valent, M.D.
Journal: Blood
Blood (2011) 118 (21): 961.
https://doi.org/10.1182/blood.V118.21.961.961
Published: 2011
Journal Articles

Small-Molecule Inhibition of BRD4 Is a Novel Promising Approach to Therapeutically Target Leukemia Stem Cells in AML,

Harald Herrmann, M.D., Katharina Blatt, M.Sc., Junwei Shi, Amy R. Rappaport, Karoline V. Gleixner, M.D., Sabine Cerny-Reiterer, D.V.M., Barbara Peter, D.V.M., Eric Wang, Wolfgang R. Sperr, M.D., James E. Bradner, MD, Scott W. Lowe, Ph.D., Christopher R. Vakoc, M.D., Ph.D., Johannes Zuber, M.D., Peter Valent, M.D.
Journal: Blood
Blood (2011) 118 (21): 3484.
https://doi.org/10.1182/blood.V118.21.3484.3484
Published: 2011
Journal Articles

BCR/ABL+ CML Stem Cells (CD34+/CD38-) Express High Levels of CD33 and Are Responsive to a CD33-Targeting Drug: a New Potential Concept for Eradication of CML Stem Cells.

Harald Herrmann, M.D., Sabine Cerny-Reiterer, D.V.M., Karoline V. Gleixner, M.D., Katharina Blatt, M.Sc., Susanne Herndlhofer, Hermine Agis, M.D., Werner Rabitsch, M.D., Berthold Streubel, M.D., Gerlinde Mitterbauer-Hohendanner, M.D., Wolfgang R. Sperr, M.D., Christian Sillaber, M.D., Peter Valent, M.D.
Journal: Blood
Blood (2010) 116 (21): 3382.
https://doi.org/10.1182/blood.V116.21.3382.3382
Published: 2010
Journal Articles

Identification of Novel Surface Markers and Targets In Neoplastic Stem Cells In AML and CML: a Flow-Gene-Flow Screen Approach.

Harald Herrmann, M.D., Sabine Cerny-Reiterer, D.V.M., Irina Sadovnik, M.Sc., Viviane Winter, M.D., Katharina Blatt, M.Sc., Werner Rabitsch, M.D., Wolfgang R. Sperr, M.D., Elena De Angelis, Ph.D., Steve Holmes, Ph.D., Peter Valent, M.D.
Journal: Blood
Blood (2010) 116 (21): 1575.
https://doi.org/10.1182/blood.V116.21.1575.1575
Published: 2010