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Journal Articles

Systems medicine dissection of chr1q-amp reveals a novel PBX1-FOXM1 axis for targeted therapy in multiple myeloma

Nikolaos Trasanidis, Alexia Katsarou, Kanagaraju Ponnusamy, Yao-An Shen, Ioannis V. Kostopoulos, Bien Bergonia, Keren Keren, Paudel Reema, Xiaolin Xiao, Richard M. Szydlo, Pierangela M. R. Sabbattini, Irene A. G. Roberts, Holger W. Auner, Kikkeri N. Naresh, Aristeidis Chaidos, Tian-Li Wang, Luca Magnani, Valentina S. Caputo, Anastasios Karadimitris
Journal: Blood
Blood (2022) 139 (13): 1939–1953.
https://doi.org/10.1182/blood.2021014391
Published: 2022
Includes: Supplemental data
Journal Articles

Myc and Bet Proteins Orchestrate the Early Regulatory Genome Changes Required for Osteoclast Lineage Commitment

Valentina S Caputo, Nikolaos Trasanidis, Xiaolin Xiao, Mark E Robinson, Alexia Katsarou, Kanagaraju Ponnusamy, Aristeidis Chaidos, Holger W Auner, MD PhD, Irene Roberts, Anastasios Karadimitris
Journal: Blood
Blood (2019) 134 (Supplement_1): 4329.
https://doi.org/10.1182/blood-2019-125047
Published: 2019
Journal Articles

Oncogenic MAF in Co-Operation with IRF4 Confers Extensive Chromatin Re-Arrangement in Plasma Cells and Generates 'Neo-Enhancers' That Regulate Genes Critical for Myeloma Biology

Alexia Katsarou, Nikolaos Trasanidis, Jaime Alvarez-Benayas, Foteini Papaleonidopoulou, Keren Keren, Ioannis V. Kostopoulos, Kanagaraju Ponnusamy, Xiaolin Xiao, Niklas Feldhahn, Irene Roberts, Evdoxia Hatjiharissi, Maria Papaioannou, Ian Sudbery, Aristeidis Chaidos, Valentina S Caputo, Anastasios Karadimitris
Journal: Blood
Blood (2019) 134 (Supplement_1): 3783.
https://doi.org/10.1182/blood-2019-122371
Published: 2019
Journal Articles

PBX1 Co-Operates with FOXM1 to Regulate Myeloma Cell Proliferation and to Define an Ultra High-Risk chr1q Gain Myeloma Patient Subgroup

Nikolaos Trasanidis, Alexia Katsarou, Bien Bergonia, Keren Keren, Ioannis V. Kostopoulos, Kanagaraju Ponnusamy, Reema Paudel, Xiaolin Xiao, Holger W Auner, MD PhD, Irene Roberts, Kikkeri Naresh, MD, Aristeidis Chaidos, Luca Magnani, Valentina S Caputo, Anastasios Karadimitris
Journal: Blood
Blood (2019) 134 (Supplement_1): 3760.
https://doi.org/10.1182/blood-2019-124109
Published: 2019
Journal Articles

Novel ZBP1-IRF3 Dependency in Multiple Myeloma Mediated By IRF3-Driven Regulation of Cell Cycle Genes

Kanagaraju Ponnusamy, Maria-Myrsini Tzioni, MS, Murshida Begum, MS, Mark E Robinson, Valentina S Caputo, Alexia Katsarou, Nikolaos Trasanidis, Xiaolin Xiao, Ioannis V. Kostopoulos, Deena Iskander, MD, Irene Roberts, Pritesh Trivedi, MSc, Holger W Auner, MD PhD, Kikkeri Naresh, MD, Aristeidis Chaidos, Anastasios Karadimitris
Journal: Blood
Blood (2019) 134 (Supplement_1): 2521.
https://doi.org/10.1182/blood-2019-125768
Published: 2019
Journal Articles

Distinct Chromatin Accessibility Changes, Aberrant Transcription Factor Networks Combined with Novel Oncogenic Enhancers Characterise Myeloma-Initiating Genetic Events

Nikolaos Trasanidis, Jaime Alvarez-Benayas, Alexia Katsarou, Aristeidis Chaidos, Philippa C May, Kanagaraju Ponnusamy, Xiaolin Xiao, Marco Bua, MD, Maria Atta, MD, Irene Roberts, Holger W Auner, MD PhD, Evdoxia Hatjiharissi, Maria Papaioannou, Valentina S Caputo, Ian Sudbery, Anastasios Karadimitris
Journal: Blood
Blood (2019) 134 (Supplement_1): 1769.
https://doi.org/10.1182/blood-2019-124761
Published: 2019
Journal Articles

Myeloma Cell Addiction to the Transcription Factor TCF11

Valentina Caputo, PhD, Katerina Goudevenou, PhD, Nikolaos Trasanidis, BSc, MSc, Kyriaki Petevi, MD, Xiaolin Xiao, PhD, Kanagaraju Ponnusamy, PhD, Deena Iskander, MD, David Pitcher, PhD, Antonia Rotolo, MD, Holger W. Auner, MD PhD, Aristeidis Chaidos, MD PhD, Anastasios Karadimitris, PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 1194.
https://doi.org/10.1182/blood.V130.Suppl_1.1194.1194
Published: 2017