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Journal Articles

T Cell Landscape of Immune Aplastic Anemia Reveals a Convergent Antigen-Specific Signature

Jani Huuhtanen, BMed, Sofie Lundgren, BMed, Mikko A Keränen, MD PhD, Xingmin Feng, PhD, Cassandra M Kerr, MS, Emmi Jokinen, MSc, Markus Heinonen, PhD, Paula Savola, MD PhD, Tiina Kelkka, PhD, Freja Ebeling, MD PhD, Georgina L Ryland, Lucy Fox, Piers Blombery, MBBS, Eva Hellstrom Lindberg, MD PhD, Neal S. Young, MD, Jaroslaw P. Maciejewski, MD PhD, Harri Lähdesmäki, PhD, Satu Mustjoki, MD PhD

Blood (2019) 134 (Supplement_1): 108.

https://doi.org/10.1182/blood-2019-127790

Published: 2019

Journal Articles

Single-Cell RNA Sequencing of Healthy Human Marrow Hematopoietic Cells

Xin Zhao, MD PhD, Shouguo Gao, PhD, Sachiko Kajigaya, PhD, Qingguo Liu, MD PhD, Zhijie Wu, MD, Xingmin Feng, PhD, Fengkui Zhang, MD, Neal S. Young, MD

Blood (2019) 134 (Supplement_1): 4997.

https://doi.org/10.1182/blood-2019-123249

Published: 2019

Journal Articles

Comparative Single Cell Transcriptomic Analysis of the Hematopoietic System between Human and Mouse

Shouguo Gao, PhD, Zhijie Wu, MD, Xingmin Feng, PhD, Jichun Chen, PhD, Sachiko Kajigaya, PhD, Neal S. Young, MD

Blood (2019) 134 (Supplement_1): 3706.

https://doi.org/10.1182/blood-2019-123204

Published: 2019

Journal Articles

Spectrum and Clinical Significance of HLA Class I Alleles and Their Somatic Mutations in Immune Aplastic Anemia

Yoshitaka Zaimoku, MD PhD, Sharon D. Adams, MT, CHS (ABHI), Bhavisha A Patel, MD, Audrey Ai Chin Lee, MS, CHT (ABHI), Sachiko Kajigaya, PhD, Xingmin Feng, PhD, Olga Rios, RN, Holly DiFebo, RN, Lemlem Alemu, BS, Diego Quinones Raffo, MSc, Emma M. Groarke, MD, Willy A. Flegel, MD, Neal S. Young, MD

Blood (2019) 134 (Supplement_1): 3738.

https://doi.org/10.1182/blood-2019-127359

Published: 2019

Journal Articles

Deficit of Circulating CD19 + CD24 hi CD38 hi Regulatory B Cells in Severe Aplastic Anemia

Yoshitaka Zaimoku, MD PhD, Bhavisha A Patel, MD, Sachiko Kajigaya, PhD, Xingmin Feng, PhD, Lemlem Alemu, BS, Diego Quinones Raffo, MSc, Emma M. Groarke, MD, Neal S. Young, MD

Blood (2019) 134 (Supplement_1): 1219.

https://doi.org/10.1182/blood-2019-127053

Published: 2019

Journal Articles

Sirolimus Augments Hematopoietic Stem and Progenitor Cell Recovery from Hematopoietic Stress

Xingmin Feng, PhD, Zenghua Lin, MD, Maile K. Hollinger, BA, Wanling Sun, MD PhD, Zhijie Wu, MD PhD, Kaylind Batey, BS, Keyvan Keyvanfar, BS, Jichun Chen, PhD, Neal S. Young, MD

Blood (2018) 132 (Supplement 1): 1310.

https://doi.org/10.1182/blood-2018-99-113488

Published: 2018

Journal Articles

Tumor Necrosis Factor-α in Target Cells but Not in Effector Cells Plays Critical Roles in Development of Murine Immune-Mediated Bone Marrow Failure

Xingmin Feng, PhD, Wanling Sun, MD PhD, Zhijie Wu, MD PhD, Zenghua Lin, MD, Maile K Hollinger, BA, Jichun Chen, PhD, Neal S. Young, MD

Blood (2017) 130 (Supplement 1): 778.

https://doi.org/10.1182/blood.V130.Suppl_1.778.778

Published: 2017

Journal Articles

T Cells Trafficking to Bone Marrow Have Different Characteristics from Those to Other Organs in an Immune-Mediated Bone Marrow Failure Mouse Model

Zenghua Lin, MD, Xingmin Feng, PhD, Wanling Sun, MD PhD, Zhijie Wu, MD PhD, Maile K Hollinger, BA, Jichun Chen, PhD, Hong Liu, MD PhD, Neal S. Young, MD

Blood (2017) 130 (Supplement 1): 2455.

https://doi.org/10.1182/blood.V130.Suppl_1.2455.2455

Published: 2017

Journal Articles

Single-Cell RNA-Seq Reveals the Differentiation Hierarchy of Normal Human Bone Marrow and a Distinct Transcriptome Signature of Monosomy 7 Cells

Xin Zhao, MD PhD, Shouguo Gao, PhD, Xingmin Feng, PhD, Delong Liu, PhD, Sachiko Kajigaya, PhD, Zhijie Wu, MD, Qingguo Liu, MD, Keyvan Keyvanfar, BS, Marie J. Desierto, BS, Danielle M. Townsley, MD, Xujing Wang, PhD, Neal S. Young, MD

Blood (2016) 128 (22): 574.

https://doi.org/10.1182/blood.V128.22.574.574

Published: 2016

Journal Articles

T Cell Transcriptomes from Paroxysmal Nocturnal Hemoglobinuria Patients Reveal Novel Signaling Pathways

Kohei Hosokawa, MDPhD, Sachiko Kajigaya, PhD, Keyvan Keyvanfar, BS, Qiao Wangmin, BS, Yanling Xie, MS, Olga Rios, RN, Barbara Weinstein, RN, Maria del Pilar Fernandez Ibanez, BS, Danielle M. Townsley, MD, Xingmin Feng, PhD, Neal S. Young, MD

Blood (2016) 128 (22): 1042.

https://doi.org/10.1182/blood.V128.22.1042.1042

Published: 2016

Journal Articles

Heterozygous RTEL1 variants in Patients with Bone Marrow Failure Associate with Telomere Dysfunction in the Absence of Telomere Shortening

Fernanda Gutierrez-Rodrigues, MSc, PharmD, Sachiko Kajigaya, PhD, Xingmin Feng, PhD, Maria del Pilar Fernandez Ibanez, MS, Marie J. Desierto, BS, Keyvan Keyvanfar, BS, Zejuan Li, MD PhD, Soma Das, PhD, Rodrigo T. Calado, MD PhD, Danielle M. Townsley, MD, Neal S. Young

Blood (2016) 128 (22): 1044.

https://doi.org/10.1182/blood.V128.22.1044.1044

Published: 2016

Journal Articles

Oligoclonal Expansion of Effector Memory CD8+CD57+ T Cells May Sustain Bone Marrow Destruction in Aplastic Anemia

Valentina Giudice, MD, Xingmin Feng, PhD, Lin Zenghua, MD, Maria del Pilar Fernandez Ibanez, MS, Keyvan Keyvanfar, BS, Carmine Selleri, MD, Neal S. Young, MD

Blood (2016) 128 (22): 3898.

https://doi.org/10.1182/blood.V128.22.3898.3898

Published: 2016

Journal Articles

Fluorescent Cell Barcoding As New Flow Cytometric Technique for Multiplexed Phenotyping and Signaling Profiling in Hematologic Patients

Valentina Giudice, MD, Xingmin Feng, PhD, Sachiko Kajigaya, PhD, Angelique Biancotto, PhD, Neal S. Young

Blood (2016) 128 (22): 5033.

https://doi.org/10.1182/blood.V128.22.5033.5033

Published: 2016

Journal Articles

A Plasma microRNA Signature As a Biomarker for Acquired Aplastic Anemia

Kohei Hosokawa, MD PhD, Sachiko Kajigaya, PhD, Xingmin Feng, PhD, Marie J. Desierto, BS, Maria del Pilar Fernandez Ibanez, BS, Olga Rios, RN, Barbara Weinstein, RN, Phillip Scheinberg, MD, Danielle M. Townsley, MD, Neal S. Young, MD

Blood (2016) 128 (22): 728.

https://doi.org/10.1182/blood.V128.22.728.728

Published: 2016

Journal Articles

Rapamycin Is Highly Effective in a Mouse Model of Immune-Mediated Bone Marrow Failure By Mechanisms Distinct from Cyclosporine

Xingmin Feng, PhD, Zenghua Lin, MD PhD, Marie Desierto, Keyvan Keyvanfar, BS, Daniela Malide, PhD, Jichun Chen, PhD, Neal S. Young, MD

Blood (2015) 126 (23): 1202.

https://doi.org/10.1182/blood.V126.23.1202.1202

Published: 2015

Journal Articles

Activity of the Telomerase Inhibitor GRN163L (Imetelstat) on Acute Myeloblastic Leukemia Blasts Is Enhanced By DNA Methyltransferase Inhibitors Irrespective of TERT Promoter Methylation Status

Caroline R Cantilena, BA, Xin Zhao, MD PhD, Sachiko Kajigaya, PhD, Neil Dunavin, MD, Xin Tian, PhD, Stephen A. Strickland, MD, Bipin N. Savani, MD, Sanjay R. Mohan, MD, Katayoun Rezvani, MDPhD, Xingmin Feng, PhD, Danielle M. Townsley, MD, Minoo Battiwalla, MDMS, Sawa Ito, MD, Austin John Barrett, MDFRCP,FRCPath

Blood (2015) 126 (23): 1267.

https://doi.org/10.1182/blood.V126.23.1267.1267

Published: 2015

Journal Articles

Whole Transcriptome Sequencing Identifies Novel Pathways Associated with Paroxysmal Nocturnal Hemoglobinuria- Increased CXCR2 Expression in PNH Granulocytes

Kohei Hosokawa, MDPhD, Sachiko Kajigaya, PhD, Keyvan Keyvanfar, BS, Danielle M. Townsley, MD, Bogdan Dumitriu, MD, Marie Desierto, Olga Rios, Barbara Weinstein, Xingmin Feng, PhD, Neal S. Young, MD

Blood (2015) 126 (23): 3608.

https://doi.org/10.1182/blood.V126.23.3608.3608

Published: 2015

Journal Articles

Persistent Elevation of Plasma Thrombopoietin Levels in Severe Aplastic Anemia, Even with Hematologic Recovery

Xin Zhao, MD PhD, Xingmin Feng, PhD, Danielle M. Townsley, MD, Thomas Winkler, MD, Ronan Desmond, MD, Matthew J. Olnes, MD PhD, Harshraj Leuva, Bogdan Dumitriu, MD, Cynthia E. Dunbar, MD, Neal S. Young, MD

Blood (2015) 126 (23): 3609.

https://doi.org/10.1182/blood.V126.23.3609.3609

Published: 2015

Journal Articles

High Frequency of Circulating CD8 + Memory Stem T Cells in Acquired Aplastic Anemia

Kohei Hosokawa, MDPhD, Pawel Muranski, MD, Xingmin Feng, PhD, Danielle M. Townsley, MD, Baoying Liu, PhD, Jared Knickelbein, MD, Keyvan Keyvanfar, BS, Bogdan Dumitriu, MD, Sawa Ito, MD, Sachiko Kajigaya, PhD, James G. Taylor, MD, Mariana J. Kaplan, MD, Robert B. Nussenblatt, MD, Austin John Barrett, MDFRCP,FRCPath, John O'Shea, MD, Neal S. Young, MD

Blood (2015) 126 (23): 3613.

https://doi.org/10.1182/blood.V126.23.3613.3613

Published: 2015

Journal Articles

Eltrombopag Added to Standard Immunosuppression for Aplastic Anemia Accelerates Count Recovery and Increases Response Rates

Danielle M. Townsley, MD, Bogdan Dumitriu, MD, Phillip Scheinberg, MD, Ronan Desmond, MD, FRCPath, Xingmin Feng, PhD, Olga Rios, RN, Barbara Weinstein, RN, Janet Valdez, PA-C, Thomas Winkler, MD, Marie Desierto, BS, Harshraj Leuva, MBBS, Colin Wu, PhD, Katherine R. Calvo, MD, PhD, Andre Larochelle, MD, PhD, Cynthia E. Dunbar, MD, Neal S. Young, MD

Blood (2015) 126 (23): LBA-2.

https://doi.org/10.1182/blood.V126.23.LBA-2.LBA-2

Published: 2015

NARROW

T Cell Landscape of Immune Aplastic Anemia Reveals a Convergent Antigen-Specific Signature

Single-Cell RNA Sequencing of Healthy Human Marrow Hematopoietic Cells

Comparative Single Cell Transcriptomic Analysis of the Hematopoietic System between Human and Mouse

Spectrum and Clinical Significance of HLA Class I Alleles and Their Somatic Mutations in Immune Aplastic Anemia

Deficit of Circulating CD19 + CD24 hi CD38 hi Regulatory B Cells in Severe Aplastic Anemia

Sirolimus Augments Hematopoietic Stem and Progenitor Cell Recovery from Hematopoietic Stress

Tumor Necrosis Factor-α in Target Cells but Not in Effector Cells Plays Critical Roles in Development of Murine Immune-Mediated Bone Marrow Failure

T Cells Trafficking to Bone Marrow Have Different Characteristics from Those to Other Organs in an Immune-Mediated Bone Marrow Failure Mouse Model

Single-Cell RNA-Seq Reveals the Differentiation Hierarchy of Normal Human Bone Marrow and a Distinct Transcriptome Signature of Monosomy 7 Cells

T Cell Transcriptomes from Paroxysmal Nocturnal Hemoglobinuria Patients Reveal Novel Signaling Pathways

Heterozygous RTEL1 variants in Patients with Bone Marrow Failure Associate with Telomere Dysfunction in the Absence of Telomere Shortening

Oligoclonal Expansion of Effector Memory CD8+CD57+ T Cells May Sustain Bone Marrow Destruction in Aplastic Anemia

Fluorescent Cell Barcoding As New Flow Cytometric Technique for Multiplexed Phenotyping and Signaling Profiling in Hematologic Patients

A Plasma microRNA Signature As a Biomarker for Acquired Aplastic Anemia

Rapamycin Is Highly Effective in a Mouse Model of Immune-Mediated Bone Marrow Failure By Mechanisms Distinct from Cyclosporine

Activity of the Telomerase Inhibitor GRN163L (Imetelstat) on Acute Myeloblastic Leukemia Blasts Is Enhanced By DNA Methyltransferase Inhibitors Irrespective of TERT Promoter Methylation Status

Whole Transcriptome Sequencing Identifies Novel Pathways Associated with Paroxysmal Nocturnal Hemoglobinuria- Increased CXCR2 Expression in PNH Granulocytes

Persistent Elevation of Plasma Thrombopoietin Levels in Severe Aplastic Anemia, Even with Hematologic Recovery

High Frequency of Circulating CD8 + Memory Stem T Cells in Acquired Aplastic Anemia

Eltrombopag Added to Standard Immunosuppression for Aplastic Anemia Accelerates Count Recovery and Increases Response Rates

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American Society of Hematology

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ASH Publications

American Society of Hematology

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