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Xuejie Chen
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Journal Articles

γ-Glutamyl carboxylase mutations differentially affect the biological function of vitamin K–dependent proteins

Zhenyu Hao, Da-Yun Jin, Xuejie Chen, Leon J. Schurgers, Darrel W. Stafford, Jian-Ke Tie
Journal: Blood
Blood (2021) 137 (4): 533–543.
https://doi.org/10.1182/blood.2020006329
Published: 2021
Includes: Supplemental data
Journal Articles

A cell-based high-throughput screen identifies drugs that cause bleeding disorders by off-targeting the vitamin K cycle

Xuejie Chen, Caihong Li, Da-Yun Jin, Brian Ingram, Zhenyu Hao, Xue Bai, Darrel W. Stafford, Keping Hu, Jian-Ke Tie
Journal: Blood
Blood (2020) 136 (7): 898–908.
https://doi.org/10.1182/blood.2019004234
Published: 2020
Includes: Supplemental data
Journal Articles

Evaluation of oral anticoagulants with vitamin K epoxide reductase in its native milieu

Xuejie Chen, Da-Yun Jin, Darrel W. Stafford, Jian-Ke Tie
Journal: Blood
Blood (2018) 132 (18): 1974–1984.
https://doi.org/10.1182/blood-2018-05-846592
Published: 2018
Includes: Supplemental data
Journal Articles

Warfarin and vitamin K epoxide reductase: a molecular accounting for observed inhibition

Sangwook Wu, Xuejie Chen, Da-Yun Jin, Darrel W. Stafford, Lee G. Pedersen, Jian-Ke Tie
Journal: Blood
Blood (2018) 132 (6): 647–657.
https://doi.org/10.1182/blood-2018-01-830901
Published: 2018
Includes: Multimedia, Supplemental data