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Journal Articles

Impact of HLA Evolutionary Divergence on Clinical Features of Patients with Aplastic Anemia and Paroxysmal Nocturnal Hemoglobinuria

Simona Pagliuca, MD, Carmelo Gurnari, MD, Diego Chowell, PhD, Chirag Krishna, Bhumika J. Patel, MD, Hassan Awada, MD, Cassandra M Kerr, MS, Sunisa Kongkiatkamon, MD, Ashwin Kishtagari, MBBS, Thomas Laframboise, PhD, Yogenthiran Saunthararajah, MD, Babal K. Jha, PhD, Valeria Visconte, PhD, Timothy Chan, MD PhD, Jaroslaw Maciejewski, PhD

Blood (2020) 136 (Supplement 1): 2–3.

https://doi.org/10.1182/blood-2020-142693

Published: 2020

Journal Articles

The Application of Machine Learning to Improve the Subclassification and Prognostication of Acute Myeloid Leukemia

Blood (2020) 136 (Supplement 1): 28.

https://doi.org/10.1182/blood-2020-139013

Published: 2020

Journal Articles

Role of Oligoadenylate Synthetases in Myeloid Neoplasia

Metis Hasipek, PhD, Yihong Guan, PhD, Dale Grabowski, BS, Xiaorong Gu, PhD, Yogenthiran Saunthararajah, MD, Robert Silverman, PhD, George R Stark, PhD, Jaroslaw Maciejewski, PhD, Babal K. Jha, PhD

Blood (2020) 136 (Supplement 1): 29–30.

https://doi.org/10.1182/blood-2020-142457

Published: 2020

Journal Articles

Double Genetic Hits and Subclonal Mosaicism in the Ras Signaling Pathway in Myeloid Neoplasia

Sunisa Kongkiatkamon, MD, Yasunobu Nagata, MD PhD, Vera Adema, PhD, Hassan Awada, MD, Misam Zawit, MD, Laila Terkawi, Simona Pagliuca, MD, Carmelo Gurnari, MD, Cassandra M Kerr, MS, Mikkael A. Sekeres, MD MS, Hetty E. Carraway, MD MBA, Yogenthiran Saunthararajah, MD, Bhumika J. Patel, MD, Jaroslaw P. Maciejewski, MD PhD, Valeria Visconte, PhD

Blood (2020) 136 (Supplement 1): 34–35.

https://doi.org/10.1182/blood-2020-143210

Published: 2020

Journal Articles

Venetoclax Inhibition of Pyrimidine Synthesis Guides Methods for Integration with Decitabine or 5-Azacytidine That Are Non-Myelosuppressive

Xiaorong Gu, PhD, Rita Tohme, PhD, Mendel Goldfinger, MD, Benjamin K. Tomlinson, MD, Nneha Sakre, PhD, Shannon Hanmer, Babal K. Jha, PhD, Jaroslaw P. Maciejewski, MD PhD, Amit Verma, MBBS, Yogenthiran Saunthararajah, MD

Blood (2020) 136 (Supplement 1): 26–27.

https://doi.org/10.1182/blood-2020-143200

Published: 2020

Journal Articles

Inhibition of Critical DNA Dioxygenase Activity in IDH1/2 Mutant Myeloid Neoplasms

Simona Pagliuca, MD, Yihong Guan, PhD, Anand D. Tiwari, PhD, Dale Grabowski, BS, Carmelo Gurnari, MD, Cassandra M Kerr, MS, Sunisa Kongkiatkamon, MD, Metis Hasipek, PhD, Laila Terkawi, Misam Zawit, MBBS, Hassan Awada, MD, Valeria Visconte, PhD, Yogenthiran Saunthararajah, MD, James G Phillips, PhD, Jaroslaw P. Maciejewski, MD PhD, Babal K. Jha, PhD

Blood (2020) 136 (Supplement 1): 28.

https://doi.org/10.1182/blood-2020-143094

Published: 2020

Journal Articles

TET2 Inhibitory Effects of Eltrombopag Contribute Its Hematopoietic Activity

Yihong Guan, PhD, Metis Hasipek, PhD, Bhumika J. Patel, MD, Dale Grabowski, BS, Anand D. Tiwari, PhD, Sunisa Kongkiatkamon, MD, Cassandra M Kerr, MS, Aziz Nazha, MD, Yogenthiran Saunthararajah, MD, Mikkael A. Sekeres, MD MS, Jaroslaw P. Maciejewski, MD PhD, Babal K. Jha, PhD

Blood (2020) 136 (Supplement 1): 2–3.

https://doi.org/10.1182/blood-2020-142875

Published: 2020

Journal Articles

Combinatorial Administration of Pharmacological Inhibitors Targeting DNMT1 and KDM1A Produces Synergistic and Additive Increases in F Retiulocytes and γ-Globin Expression in Normal Baboons

Vinzon Ibanez, B.S., Kestis Vaitkus, Robert E. Molokie, MD, Yogenthiran Saunthararajah, MD, Donald Lavelle, PhD

Blood (2020) 136 (Supplement 1): 5.

https://doi.org/10.1182/blood-2020-136599

Published: 2020

Journal Articles

Effect of Nicotinamide, 1-Methylnicotinamide, and N'-Methylnicotinamide on Erythroid Colony Formation and γ-Globin Expression in Cultured Baboon CD34+ Cells

Donald Lavelle, PhD, Vinzon Ibanez, B.S., Kestis Vaitkus, Yogenthiran Saunthararajah, MD, Robert E. Molokie, MD

Blood (2020) 136 (Supplement 1): 4–5.

https://doi.org/10.1182/blood-2020-133974

Published: 2020

Journal Articles

Feedback Responses of the Pyrimidine Metabolism Network Mediate Resistance to Decitabine and 5-Azacytidine

Xiaorong Gu, PhD, Rita Tohme, PhD, Benjamin K. Tomlinson, MD, Lisa Durkin, Caroline Schuerger, Asmaa M Zidan, MB, BCh, Tomas Radivoyevitch, PhD, Hetty E. Carraway, MD MBA, Ronald Sobecks, MD, Betty K. Hamilton, MD, Alan Lichtin, MD, Jaroslaw P. Maciejewski, MD PhD, Yogenthiran Saunthararajah, MD

Blood (2019) 134 (Supplement_1): 537.

https://doi.org/10.1182/blood-2019-125823

Published: 2019

Journal Articles

FA Gene Carrier Status Predisposes to Myeloid Neoplasms and Bone Marrow Failure in Adults

Jibran Durrani, Hassan Awada, MD, Wenyi Shen, MD, Cassandra M Kerr, MS, Vera Adema, PhD, Sunisa Kongkiatkamon, Ashwin Kishtagari, MBBS, Samuel Li, Yasunobu Nagata, MD PhD, Sanghee Hong, MD, Aziz Nazha, MD, Bhumika J. Patel, MD, Yogenthiran Saunthararajah, MD, Hetty E. Carraway, MD MBA, Valeria Visconte, PhD, Seth J. Corey, MD, Mikkael A. Sekeres, MD MS, Thomas Laframboise, PhD, Jaroslaw P. Maciejewski, MD PhD

Blood (2019) 134 (Supplement_1): 452.

https://doi.org/10.1182/blood-2019-130142

Published: 2019

Journal Articles

Eltrombopag Creates a Transient Chemical Phenocopy of TET2 Loss of Function That Contributes to Hematopoietic Precursor Expansion

Yihong Guan, PhD, Bhumika J. Patel, MD, Metis Hasipek, PhD, Dale Grabowski, BS, Hassan Awada, MD, Cassandra M Kerr, MS, Valeria Visconte, PhD, Aziz Nazha, MD, Yogenthiran Saunthararajah, MD, Mikkael A. Sekeres, MD MS, Jaroslaw P. Maciejewski, MD PhD, Babal K. Jha, PhD

Blood (2019) 134 (Supplement_1): 453.

https://doi.org/10.1182/blood-2019-131525

Published: 2019

Journal Articles

CUL1: Novel Therapeutic Target in Myeloid Neoplasms Harboring -7/Del(7q)

Blood (2019) 134 (Supplement_1): 1281.

https://doi.org/10.1182/blood-2019-129196

Published: 2019

Journal Articles

Large Granular Lymphocytic Leukemia Coexists with Clonal Hematopoiesis of Indeterminate Potential

Jibran Durrani, Hassan Awada, Ashwin Kishtagari, MBBS, Cassandra M Kerr, MS, Vera Adema, PhD, Yasunobu Nagata, MD PhD, Teodora Kuzmanovic, Sanghee Hong, MD, Sunisa Kongkiatkamon, Alan Lichtin, MD, Aziz Nazha, MD, Bhumika J. Patel, MD, Yogenthiran Saunthararajah, MD, Hetty E. Carraway, MD MBA, Valeria Visconte, PhD, Mikkael A. Sekeres, MD MS, Jaroslaw P. Maciejewski, MD PhD

Blood (2019) 134 (Supplement_1): 3743.

https://doi.org/10.1182/blood-2019-129330

Published: 2019

Journal Articles

A Single Arm, Phase II Study of Eltrombopag to Enhance Platelet Count Recovery in Older Patients with Acute Myeloid Leukemia (AML) Undergoing Remission Induction Therapy

Sudipto Mukherjee, MD PhD MPH, Hong Li, Brian P. Hobbs, PhD, Aaron T. Gerds, MD MS, Anjali S. Advani, MD, Hetty E. Carraway, MD MBA, Aziz Nazha, MD, Samjhana Bogati, RN, Eric Parsons, RN, Benjamin Pannell, Matt Kalaycio, MD, Yogenthiran Saunthararajah, MD, Jaroslaw P. Maciejewski, MD PhD, Mikkael A. Sekeres, MD MS

Blood (2019) 134 (Supplement_1): 2595.

https://doi.org/10.1182/blood-2019-132178

Published: 2019

Journal Articles

Iron Catalyzed Hydrogen Sulfide and Its Prevalence during Oxidative Events in Sickle Cell Disease

Jie Yang, PhD, Nazmin Bithi, B.Sc, Christopher Link, B.Sc, Yogenthiran Saunthararajah, MD, Christopher Hine, PhD

Blood (2019) 134 (Supplement_1): 3534.

https://doi.org/10.1182/blood-2019-122985

Published: 2019

Journal Articles

Integrated Analysis of Copy-Number Alterations and Gene Mutations in 2,000 Patients with Myeloid Neoplasms

Ryunosuke Saiki, Yusuke Shiozawa, MD PhD, Tetsuichi Yoshizato, MD PhD, Yasuhito Nannya, MD PhD, June Takeda, MD, Kenichi Yoshida, MD PhD, Yuichi Shiraishi, PhD, Hiroko Tanaka, BA, Kenichi Chiba, PhD, Yoshiko Atsuta, MD PhD, Makoto Onizuka, MD PhD, Hidehiro Itonaga, MD PhD, Masashi Sanada, MD, Yoshinobu Kanda, MD PhD, Bartlomiej Przychodzen, Mikkael A. Sekeres, MD MS, Kathryn Guinta, Yogenthiran Saunthararajah, MD, Lee-Yung Shih, MD, Shuichi Miyawaki, MD PhD, Tsuyoshi Nakamaki, MD PhD, Masataka Taguchi, Shigeo Fuji, MD PhD, Nana Sasaki, MD, Nobuhiko Uoshima, MD PhD, Yasunori Ueda, MD PhD, Yasushi Miyazaki, MD PhD, Kensuke Usuki, MD PhD, Kazunori Imada, MD PhD, Akifumi Takaori-Kondo, MD PhD, Shigeru Chiba, MD PhD, Senji Kasahara, MD PhD, Toru Kiguchi, MD PhD, Hisashi Tsurumi, MD PhD, Luca Malcovati, MD, Mario Cazzola, MD, Takayuki Ishikawa, MD PhD, Satoru Miyano, PhD, Jaroslaw P. Maciejewski, MD PhD, Hideki Makishima, MD PhD, Seishi Ogawa, MD PhD

Blood (2019) 134 (Supplement_1): 4216.

https://doi.org/10.1182/blood-2019-132174

Published: 2019

Journal Articles

Extended Experience with a Very Low Dose, Metronomic, Subcutaneous Decitabine Regimen Intended to Deplete DNMT1 without Cytotoxicity

Ashwin Kishtagari, MBBS, Hassan Awada, Reda Z. Mahfouz, MD PhD, Teodora Kuzmanovic, Jibran Durrani, Cassandra M Kerr, MS, Bhumika J. Patel, MD, Valeria Visconte, PhD, Tomas Radivoyevitch, PhD, Alan Lichtin, MD, Hetty E. Carraway, MD MBA, Jaroslaw P. Maciejewski, MD PhD, Yogenthiran Saunthararajah, MD

Blood (2019) 134 (Supplement_1): 1279.

https://doi.org/10.1182/blood-2019-130579

Published: 2019

Journal Articles

BRCA1 & BRCA2 Germline Variants Are Enriched in MDS/AML and Portend Higher Average Mutational Burden

Louis Williams, MD MBA, Teodora Kuzmanovic, BA, Cassandra M. Hirsch, Bartlomiej P. Przychodzen, Yogenthiran Saunthararajah, MD, Hassan Awada, MD, Vera Adema, PhD, Amy C Graham, BS, MS, Tomas Radivoyevitch, PhD, Hetty E. Carraway, MD MBA, Aziz Nazha, Mikkael A. Sekeres, MD MS, Jaroslaw P. Maciejewski

Blood (2018) 132 (Supplement 1): 4352.

https://doi.org/10.1182/blood-2018-99-116802

Published: 2018

Journal Articles

Targeting NAD + Modulating Enzymes to Improve HSC Function in Aging and Bone Marrow Failure

Phillip J Maciejewski, Yihong Guan, Metis Hasipek, PhD, Anand D. Tiwari, PhD, Dale Grabowski, BS, James G Phillips, PhD, Yogenthiran Saunthararajah, MD, Jaroslaw P. Maciejewski, Babal K. Jha

Blood (2018) 132 (Supplement 1): 3840.

https://doi.org/10.1182/blood-2018-99-119300

Published: 2018

NARROW

Impact of HLA Evolutionary Divergence on Clinical Features of Patients with Aplastic Anemia and Paroxysmal Nocturnal Hemoglobinuria

The Application of Machine Learning to Improve the Subclassification and Prognostication of Acute Myeloid Leukemia

Role of Oligoadenylate Synthetases in Myeloid Neoplasia

Double Genetic Hits and Subclonal Mosaicism in the Ras Signaling Pathway in Myeloid Neoplasia

Venetoclax Inhibition of Pyrimidine Synthesis Guides Methods for Integration with Decitabine or 5-Azacytidine That Are Non-Myelosuppressive

Inhibition of Critical DNA Dioxygenase Activity in IDH1/2 Mutant Myeloid Neoplasms

TET2 Inhibitory Effects of Eltrombopag Contribute Its Hematopoietic Activity

Combinatorial Administration of Pharmacological Inhibitors Targeting DNMT1 and KDM1A Produces Synergistic and Additive Increases in F Retiulocytes and γ-Globin Expression in Normal Baboons

Effect of Nicotinamide, 1-Methylnicotinamide, and N'-Methylnicotinamide on Erythroid Colony Formation and γ-Globin Expression in Cultured Baboon CD34+ Cells

Feedback Responses of the Pyrimidine Metabolism Network Mediate Resistance to Decitabine and 5-Azacytidine

FA Gene Carrier Status Predisposes to Myeloid Neoplasms and Bone Marrow Failure in Adults

Eltrombopag Creates a Transient Chemical Phenocopy of TET2 Loss of Function That Contributes to Hematopoietic Precursor Expansion

CUL1: Novel Therapeutic Target in Myeloid Neoplasms Harboring -7/Del(7q)

Large Granular Lymphocytic Leukemia Coexists with Clonal Hematopoiesis of Indeterminate Potential

A Single Arm, Phase II Study of Eltrombopag to Enhance Platelet Count Recovery in Older Patients with Acute Myeloid Leukemia (AML) Undergoing Remission Induction Therapy

Iron Catalyzed Hydrogen Sulfide and Its Prevalence during Oxidative Events in Sickle Cell Disease

Integrated Analysis of Copy-Number Alterations and Gene Mutations in 2,000 Patients with Myeloid Neoplasms

Extended Experience with a Very Low Dose, Metronomic, Subcutaneous Decitabine Regimen Intended to Deplete DNMT1 without Cytotoxicity

BRCA1 & BRCA2 Germline Variants Are Enriched in MDS/AML and Portend Higher Average Mutational Burden

Targeting NAD + Modulating Enzymes to Improve HSC Function in Aging and Bone Marrow Failure

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American Society of Hematology

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ASH Publications

American Society of Hematology

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