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Journal Articles

Mutated Nucleophosmin 1 (NPM1) Is an Immunogenic Target and Patients with NPM1 mut Acute Myeloid Leukemia (AML) Showed High Expression of Different Leukemia-Associated Antigens (LAAs)

Susanne Hofmann, Vanessa Schneider, Lars Bullinger, Yoko Ono, Anita Schmitt, Lu Zhang, Marlies Götz, Konstanze Döhner, MD, Ph.D, Joannis Mytilineos, Markus Wiesneth, Hartmut Döhner, MD, Michael Schmitt, Jochen Greiner, MD
Journal: Blood
Blood (2012) 120 (21): 3592.
https://doi.org/10.1182/blood.V120.21.3592.3592
Published: 2012
Journal Articles

Mutated regions of nucleophosmin 1 elicit both CD4 + and CD8 + T-cell responses in patients with acute myeloid leukemia

Jochen Greiner, Yoko Ono, Susanne Hofmann, Anita Schmitt, Elmar Mehring, Marlies Götz, Philippe Guillaume, Konstanze Döhner, Joannis Mytilineos, Hartmut Döhner, Michael Schmitt
Journal: Blood
Blood (2012) 120 (6): 1282–1289.
https://doi.org/10.1182/blood-2011-11-394395
Published: 2012
Journal Articles

The Mutated Region of Cytoplasmatic Nucleophosmine 1 (NPM1) Elicits Both CD4+ and CD8+ T Cell Responses

Jochen Greiner, MD, Yoko Ono, Susanne Hofmann, Vanessa Schneider, Anita Schmitt, Lu Zhang, Elmar Mehring, Marlies Götz, Konstanze Döhner, Joannis Mytilineos, Markus Wiesneth, Hartmut Döhner, MD, Michael Schmitt, MD, PhD
Journal: Blood
Blood (2011) 118 (21): 2569.
https://doi.org/10.1182/blood.V118.21.2569.2569
Published: 2011
Journal Articles

Peripheral Tolerance to PR1 Is Maintained After Uptake of Soluble Proteinas-3 and Neutrophil Elastase

Gheath Alatrash, DO, PhD, Yoko Ono, MD, Anna Sergeeva, PhD, Pariya Sukhumalchandra, BS, Mao Zhang, MPH, Kathryn Quintanilla, MS, Paul Armistead, MD, PhD, Hong He, MD, Tania Rodriguez-Cruz, BS, Karen Clise-Dwyer, PhD, Eric Wieder, PhD, Greg Lizee, PhD, Sijie Lu, PhD, Jeffrey J. Molldrem, MD
Journal: Blood
Blood (2010) 116 (21): 4301.
https://doi.org/10.1182/blood.V116.21.4301.4301
Published: 2010
Journal Articles

Levofloxacine Prophylaxis Decreases the Incidence of BK Polyoma Virus-Induced Hemorrhagic Cystitis in Patients after Allogeneic Hematopoietic Stem Cell Trans-Plantation

Yoko Ono, Manja Lache, Florian Jacob, Dominik Schneidawind, Anita Schmitt, Detlef Michel, Thomas Mertens, Hartmut Döhner, Donald Bunjes, Michael Schmitt
Journal: Blood
Blood (2008) 112 (11): 4343.
https://doi.org/10.1182/blood.V112.11.4343.4343
Published: 2008
Journal Articles

Aberrant Subcellular Localization of Azurophil Granule Proteins in Myeloid Leukemia Favors Peptide Antigen Presentation on MHC-I and Susceptibility to Killing by Cytotoxic T Lymphocytes.

Gheath Alatrash, DO, PhD, Yoko Ono, Ph.D., Sijie Lu, Ph.D., Anna Sergeeva, Ph.D., Changqing Wang, M.D., Eric Wieder, Ph.D., Jeffrey J. Molldrem, M.D.
Journal: Blood
Blood (2007) 110 (11): 4900.
https://doi.org/10.1182/blood.V110.11.4900.4900
Published: 2007
Journal Articles

Elevated Serum Neutrophil Elastase but Not Proteinase 3 Is Present in Patients with Myeloid Leukemia.

Anna Sergeeva, PhD, Yoko Ono, MD, Jeffrey J. Molldrem, MD
Journal: Blood
Blood (2006) 108 (11): 4430.
https://doi.org/10.1182/blood.V108.11.4430.4430
Published: 2006
Journal Articles

Pre-Existing Anti-GM-CSF Autoantibodies in Patients with AML, CML and MDS Are Associated with Compromised Immune Response to PR1 Peptide Vaccination.

Anna Sergeeva, PhD, Eric Wieder, PhD, Nancy Milam, Yoko Ono, MD, Rosa Rios, Jeffrey J. Molldrem, MD
Journal: Blood
Blood (2005) 106 (11): 3257.
https://doi.org/10.1182/blood.V106.11.3257.3257
Published: 2005
Journal Articles

PR1 Leukemia-Associated Antigen Is Cross-Presented by B Cells from Soluble Serum Proteases.

Yoko Ono, MD, Sijie Lu, PhD, Anna Sergeeva, PhD, Changqing Wang, Eric Wieder, PhD, Jeffrey J. Molldrem, MD
Journal: Blood
Blood (2005) 106 (11): 2397.
https://doi.org/10.1182/blood.V106.11.2397.2397
Published: 2005
Journal Articles

Antigen Cross-Presentation Allows the PR1 Leukemia-Associated Antigen To Be Processed from Both Proteinase 3 and Neutrophil Elastase to Prime T Cells.

Yoko Ono, M.D., Yukio Kondo, M.D., Anna Sergeeva, Ph.D., Olanike Akande, Pariya Sukhmalchandra, Sijie Lu, Ph.D., Eric Wieder, Ph.D., Jeffrey J. Molldrem, M.D.
Journal: Blood
Blood (2004) 104 (11): 3245.
https://doi.org/10.1182/blood.V104.11.3245.3245
Published: 2004
Journal Articles

IgG, IgA and IgM Autoantibodies to GM-CSF Are Present in AML, CML and MDS Patients and IgG Titer Is Associated with Disease Progression.

Anna Sergeeva, Ph.D., Yoko Ono, M.D., Rosa Rios, Jeffrey J. Molldrem, M.D.
Journal: Blood
Blood (2004) 104 (11): 1071.
https://doi.org/10.1182/blood.V104.11.1071.1071
Published: 2004