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Journal Articles

3-Phosphoinositide-Dependent Protein Kinase 1 (PDPK1) Is a Pivotal Cell Signaling Mediator in Multiple Myeloma

Yoshiaki Chinen, MD, Junya Kuroda, MD PhD, Yuji Shimura, MD PhD, Hisao Nagoshi, MD PhD, Miki Kiyota, MD PhD, Mio Yamamoto-Sugitani, MD PhD, Shinsuke Mizutani, MD, Natsumi Sakamoto, Masaki Ri, MD PhD, Eri Kawata, MD PhD, Tsutomu Kobayashi, MD PhD, Yosuke Matsumoto, MD PhD, Shigeo Horiike, MD PhD, Shinsuke Iida, Masafumi Taniwaki, MD PhD

Blood (2014) 124 (21): 4728.

https://doi.org/10.1182/blood.V124.21.4728.4728

Published: 2014

Journal Articles

Novel Fusion Transcripts PVT1-NSMCE2 and BF104016-NSMCE2 Resulting In Depletion Of NSMCE2 Protein In Acute Myeloid Leukemia Harboring 8q24 Amplicons

Yoshiaki Chinen, MD, Natsumi Sakamoto, Hisao Nagoshi, MD, PhD, Tomohiko Taki, MD, PhD, Satoru Kobayashi, Kazuhiro Nishida, MD, PhD, Saori Maegawa, MD, Ryuko Nakayama, MD, Miki Kiyota, MD, Shinsuke Mizutani, MD, Yuji Shimura, MD, PhD, Mio Yamamoto-Sugitani, MD, PhD, Tsutomu Kobayashi, MD, PhD, Yosuke Matsumoto, MD, PhD, Shohei Yokota, MD, PhD, Shigeo Horiike, MD, PhD, Junya Kuroda, MD, PhD, Masafumi Taniwaki, MD, PhD

Blood (2013) 122 (21): 3726.

https://doi.org/10.1182/blood.V122.21.3726.3726

Published: 2013

Journal Articles

Identification of the Novel Chimeric Gene, PVT1-WWOX , in Multiple Myeloma with 8q24 Abnormality

Hisao Nagoshi, MD, Tomohiko Taki, MD, PhD, Kazuhiro Nishida, MD, PhD, Junya Kuroda, MD, PhD, Yoshiaki Chinen, MD, Satoru Kobayashi, Yuichi Yokokawa, MD, Mio Yamamoto-Sugitani, MD, PhD, Tsutomu Kobayashi, MD, PhD, Yosuke Matsumoto, MD, PhD, Shigeo Horiike, MD, PhD, Masafumi Taniwaki, MD, PhD

Blood (2012) 120 (21): 1823.

https://doi.org/10.1182/blood.V120.21.1823.1823

Published: 2012

Journal Articles

Fingolimod (FTY720) Overcomes the Resistance to Tyrosine Kinase Inhibitors Via Dual Activation of BIM and BID in Chronic Myelogenous Leukemia

Miki Kiyota, MD, Junya Kuroda, MD, PhD, Mio Yamamoto-Sugitani, MD, PhD, Yuji Shimura, MD, Ryuko Nakayama, MD, Hisao Nagoshi, MD, Shinsuke Mizutani, MD, Yoshiaki Chinen, MD, Natsumi Sakamoto, Tsutomu Kobayashi, MD, PhD, Yosuke Matsumoto, MD, PhD, Shigeo Horiike, MD, PhD, Tomohiko Taki, MD, PhD, Masafumi Taniwaki, MD, PhD

Blood (2012) 120 (21): 3744.

https://doi.org/10.1182/blood.V120.21.3744.3744

Published: 2012

Journal Articles

Identification of Novel Fusion Genes with 28S Ribosomal DNA in Hematologic Malignancies

Satoru Kobayashi, Tomohiko Taki, MD, PhD, Hisao Nagoshi, MD, Yoshiaki Chinen, MD, Yuichi Yokokawa, MD, Hirokazu Kanegane, MD, PhD, Yosuke Matsumoto, MD, PhD, Junya Kuroda, MD, PhD, Shigeo Horiike, MD, PhD, Kazuhiro Nishida, MD, PhD, Masafumi Taniwaki, MD, PhD

Blood (2012) 120 (21): 4418.

https://doi.org/10.1182/blood.V120.21.4418.4418

Published: 2012

Journal Articles

RSK2 Ser227 Is a Therapeutic Target of Myeloma Cells Regardless of Upstream Signalings.

Yuji Shimura, MD, Junya Kuroda, MD, PhD, Hisao Nagoshi, MD, Mio Yamamoto-Sugitani, MD, PhD, Tsutomu Kobayashi, MD, PhD, Miki Kiyota, MD, Ryuko Nakayama, MD, Shinsuke Mizutani, MD, Yoshiaki Chinen, MD, Natsumi Sakamoto, Yosuke Matsumoto, MD, PhD, Shigeo Horiike, MD, PhD, Masaki Ri, MD, PhD, Yukimasa Shiotsu, PhD, Shinsuke Iida, MD, PhD, Tomohiko Taki, MD, PhD, Masafumi Taniwaki, MD, PhD

Blood (2012) 120 (21): 2945.

https://doi.org/10.1182/blood.V120.21.2945.2945

Published: 2012

Journal Articles

Leukemia Microenvironment-Specific Galectin-3 Expression of Leukemic Cells Promotes Malignant Niche Formation and Bone Marrow Lodgment of Leukemic Cells in Chronic Myelogenous Leukemia

Junya Kuroda, MD, PhD, Mio Yamamoto, Eishi Ashihara, MD, PhD, Hisao Nagoshi, MD, Tsutomu Kobayashi, MD, PhD, Yosuke Matsumoto, MD, PhD, Nasa Sasaki, Yuji Shimura, Miki Kiyota, Ryuko Nakayama, Shigeo Horiike, Taira Maekawa, MD, PhD, Masafumi Taniwaki

Blood (2011) 118 (21): 1678.

https://doi.org/10.1182/blood.V118.21.1678.1678

Published: 2011

Journal Articles

Frequent Involvement of PVT1 in Multiple Myeloma Carrying 8q24 Rearrangement and Identification of Novel PVT1-NBEA Chimeric Gene,

Hisao Nagoshi, MD, Tomohiko Taki, MD, PhD, Ichiro Hanamura, MD, PhD, Masakazu Nitta, MD, PhD, Takemi Otsuki, MD, PhD, Kazuhiro Nishida, MD, PhD, Keiko Okuda, MD, PhD, Natsumi Sakamoto, Satoru Kobayashi, Mio Yamamoto, MD, Yasuhiko Tsutsumi, MD, Tsutomu Kobayashi, MD, PhD, Yosuke Matsumoto, MD, PhD, Shigeo Horiike, MD, PhD, Junya Kuroda, MD, PhD, Masafumi Taniwaki, MD, PhD

Blood (2011) 118 (21): 3917.

https://doi.org/10.1182/blood.V118.21.3917.3917

Published: 2011

Journal Articles

Identification and Functional Significance of Novel Type of Structurally Aberrant Transcripts of DCC In B-Cell Malignancies.

Hisao Nagoshi, MD, Tomohiko Taki, MD, PhD, Junya Kuroda, MD, PhD, Kazuhiro Nishida, MD, PhD, Minako Gotoh, Keiko Okuda, MD, PhD, Satoru Kobayashi, Mio Yamamoto, MD, Yasuhiko Tsutsumi, MD, Tsutomu Kobayashi, MD, Yosuke Matsumoto, MD, PhD, Shigeo Horiike, MD, PhD, Takemi Otsuki, MD, PhD, Masafumi Taniwaki, MD, PhD

Blood (2010) 116 (21): 3623.

https://doi.org/10.1182/blood.V116.21.3623.3623

Published: 2010

Journal Articles

Identification of a Novel IGHCδ-BACH2 Fusion Transcript In B-Cell Lymphoma/Leukemia and the Expression Analysis of BACH2 Related with Other B-Cell Differentiation-Associated Genes In B-Cell Malignancies

Satoru Kobayashi, Tomohiko Taki, MD, PhD, Yoshiaki Chinen, MD, Yasuhiko Tsutsumi, MD, Muneo Ohshiro, MD, Tsutomu Kobayashi, MD, Yosuke Matsumoto, MD, PhD, Junya Kuroda, MD, PhD, Shigeo Horiike, MD, PhD, Kazuhiro Nishida, MD, PhD, Masafumi Taniwaki, MD, PhD

Blood (2010) 116 (21): 4450.

https://doi.org/10.1182/blood.V116.21.4450.4450

Published: 2010

Journal Articles

Anti-Myeloma Activity of Modified Galectin-9 through JNK and p38 MAPK Pathways.

Tsutomu Kobayashi, Junya Kuroda, MD, PhD, Eishi Ashihara, MD, PhD, Yasuhito Terui, MD, PhD, Souichi Oomizu, Mio Yamamoto, Akiko Taniyama, Yosuke Matsumoto, Shigeo Horiike, Kiyohiko Hatake, MD, PhD, Akira Yamauchi, MD, PhD, Mitsuomi Hirashima, MD, PhD, Masafumi Taniwaki, MD, PhD

Blood (2009) 114 (22): 952.

https://doi.org/10.1182/blood.V114.22.952.952

Published: 2009

Journal Articles

Alterations of DCC Gene in B-Cell Malignancies.

Hisao Nagoshi, Tomohiko Taki, Kazuhiro Nishida, Minako Goto, Satoru Kobayashi, Yasuhiko Tsutsumi, Yosuke Matsumoto, Junya Kuroda, Shigeo Horiike, Takemi Otsuki, Masafumi Taniwaki

Blood (2009) 114 (22): 4428.

https://doi.org/10.1182/blood.V114.22.4428.4428

Published: 2009

Journal Articles

Expression of Master Regulators of Helper T-Cell Differentiation in Peripheral T-Cell Lymphoma, Not Otherwise Specified by Immunohistochemical Analysis.

Yosuke Matsumoto, MD, PhD, Shigeo Horiike, MD, PhD, Muneo Ohshiro, MD, Mio Yamamoto, MD, Nana Sasaki, MD, Yasuhiko Tsutsumi, MD, Tsutomu Kobayashi, MD, Daisuke Shimizu, MD, PhD, Hitoji Uchiyama, MD, Junya Kuroda, MD, PhD, Kenichi Nomura, MD, PhD, Chihiro Shimazaki, MD, PhD, Masafumi Taniwaki, MD, PhD

Blood (2009) 114 (22): 5004.

https://doi.org/10.1182/blood.V114.22.5004.5004

Published: 2009

Journal Articles

Mutational Analysis of NOTCH1 Gene in Mature T-Cell Leukemia/Lymphoma.

Daisuke Shimizu, MD, Tomohiko Taki, MD, Atae Utsunomiya, MD, Hitoshi Nakagawa, MD, Kenichi Nomura, MD, Yosuke Matsumoto, MD, Kazuhiro Nishida, MD, Shigeo Horiike, MD, Masafumi Taniwaki, MD

Blood (2006) 108 (11): 4656.

https://doi.org/10.1182/blood.V108.11.4656.4656

Published: 2006

Journal Articles

Clinicopathological and Chromosomal Analysis of Small Intestinal Malignant Lymphoma using Fluorescence in situ Hybridization on Paraffin-Embedded Tissue Sections.

Naohisa Yoshida, M.D., Kenichi Nomura, M.D., Ph.D., Yosuke Matsumoto, M.D., Hideyuki Konishi, M.D., Ph.D., Shoji Mitsufuji, M.D., Ph.D., Shigeo Horiike, M.D., Ph.D., Tomohiko Taki, M.D., Ph.D., Masuji Morita, M.D., Ph.D., Kazuhiro Nishida, M.D., Ph.D., Takeshi Okanoue, M.D., Ph.D., Shigeo Nakamura, M.D., Ph.D., Masafumi Taniwaki, M.D., Ph.D.

Blood (2004) 104 (11): 4277.

https://doi.org/10.1182/blood.V104.11.4277.4277

Published: 2004

NARROW

3-Phosphoinositide-Dependent Protein Kinase 1 (PDPK1) Is a Pivotal Cell Signaling Mediator in Multiple Myeloma

Novel Fusion Transcripts PVT1-NSMCE2 and BF104016-NSMCE2 Resulting In Depletion Of NSMCE2 Protein In Acute Myeloid Leukemia Harboring 8q24 Amplicons

Identification of the Novel Chimeric Gene, PVT1-WWOX , in Multiple Myeloma with 8q24 Abnormality

Fingolimod (FTY720) Overcomes the Resistance to Tyrosine Kinase Inhibitors Via Dual Activation of BIM and BID in Chronic Myelogenous Leukemia

Identification of Novel Fusion Genes with 28S Ribosomal DNA in Hematologic Malignancies

RSK2 Ser227 Is a Therapeutic Target of Myeloma Cells Regardless of Upstream Signalings.

Leukemia Microenvironment-Specific Galectin-3 Expression of Leukemic Cells Promotes Malignant Niche Formation and Bone Marrow Lodgment of Leukemic Cells in Chronic Myelogenous Leukemia

Frequent Involvement of PVT1 in Multiple Myeloma Carrying 8q24 Rearrangement and Identification of Novel PVT1-NBEA Chimeric Gene,

Identification and Functional Significance of Novel Type of Structurally Aberrant Transcripts of DCC In B-Cell Malignancies.

Identification of a Novel IGHCδ-BACH2 Fusion Transcript In B-Cell Lymphoma/Leukemia and the Expression Analysis of BACH2 Related with Other B-Cell Differentiation-Associated Genes In B-Cell Malignancies

Anti-Myeloma Activity of Modified Galectin-9 through JNK and p38 MAPK Pathways.

Alterations of DCC Gene in B-Cell Malignancies.

Expression of Master Regulators of Helper T-Cell Differentiation in Peripheral T-Cell Lymphoma, Not Otherwise Specified by Immunohistochemical Analysis.

Mutational Analysis of NOTCH1 Gene in Mature T-Cell Leukemia/Lymphoma.

Clinicopathological and Chromosomal Analysis of Small Intestinal Malignant Lymphoma using Fluorescence in situ Hybridization on Paraffin-Embedded Tissue Sections.

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American Society of Hematology

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American Society of Hematology

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