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Journal Articles

Incorporating Hemoglobin Levels to Map Leukostasis Risk in Acute Leukemia Using Microvasculature-on-Chip Technologies

Jamie Oakley, MD, Evelyn K. Williams, BS, Christina Caruso, MD, Yumiko Sakurai, MSc, Reginald Tran, PhD, Glen Lew, MD, Wilbur A. Lam, MDPhD

Blood (2020) 136 (Supplement 1): 9–10.

https://doi.org/10.1182/blood-2020-137804

Published: 2020

Journal Articles

Monitoring the "Lifetime" of a Thrombus over Long Timescales By Leveraging a Novel Microvasculature-on-Chip Thrombosis Resolution Assay

Yongzhi Qiu, PhD, Yumiko Sakurai, MSc, Wilbur A. Lam, MD PhD

Blood (2019) 134 (Supplement_1): 441.

https://doi.org/10.1182/blood-2019-128718

Published: 2019

Journal Articles

Stiff Erythrocyte Subpopulations Biomechanically Induce Endothelial Inflammation in Sickle Cell Disease

Christina Caruso, MD, Xiao Zhang, BS, Yumiko Sakurai, MSc, Wei Li, MD, Meredith E. Fay, BS, Marcus A. Carden, MD, David R. Myers, PhD, Robert G. Mannino, PhD, Clinton H. Joiner, MD PhD, Michael D. Graham, PhD, Wilbur A. Lam, MD PhD

Blood (2019) 134 (Supplement_1): 3560.

https://doi.org/10.1182/blood-2019-125408

Published: 2019

Journal Articles

A Comparative Medicine Study of Platelet Biophysics Among Hemostasis Models of Different Species

Renee Copeland, BS, Oluwamayokun T. Oshinowo, Yumiko Sakurai, MSc, Meredith Ellen Fay, BS, Brian G. Petrich, PhD, Benjamin Brainard, VMD, Dipl ACVAA, ACVECC, Wilbur A Lam, MD PhD, David R. Myers, PhD

Blood (2018) 132 (Supplement 1): 869.

https://doi.org/10.1182/blood-2018-99-113107

Published: 2018

Journal Articles

Mitochondrial Uncoupling Prevents Procoagulant Platelet Formation Resulting in Decreased Thrombus Stability

Andaleb Kholmukhamedov, MD, Yumiko Sakurai, MSc, Elaissa L. Hardy, PhD, Wilbur A Lam, MD PhD, Shawn M. Jobe, MD PhD

Blood (2018) 132 (Supplement 1): 2421.

https://doi.org/10.1182/blood-2018-99-117004

Published: 2018

Journal Articles

Leveraging the Contractile Force of Platelets for Targeted Factor VIII Delivery in Hemophilia with Inhibitors

Caroline E. Hansen, BS, David R Myers, PhD, Yumiko Sakurai, MSc, Wallace Hunter Baldwin, BS, Shannon L. Meeks, MD, L. Andrew Lyon, PhD, Wilbur A Lam, MD PhD

Blood (2016) 128 (22): 81.

https://doi.org/10.1182/blood.V128.22.81.81

Published: 2016

Journal Articles

Engineering a "Self-Healing" Hydrogel-Based Microvasculature-on-a-Chip for Investigating the Effects of Cellular and Biomolecular Interactions on Endothelial Permeability in Sickle Cell Disease

Yongzhi Qiu, PhD, Byungwook Ahn, PhD, Yumiko Sakurai, MSc, Caroline Hansen, BS, Clinton H. Joiner, MD PhD, Solomon Fiifi Ofori-Acquah, PhD, Wilbur A Lam, MD PhD

Blood (2015) 126 (23): 240.

https://doi.org/10.1182/blood.V126.23.240.240

Published: 2015

Journal Articles

Characterizing Cellular Interactions Contributing to Vaso-Occlusion in Patients with Sickle Cell Disease Utilizing a Novel Endothelialized Microfluidic Device

Margo Renee Rollins, MD, Byungwook Ahn, PhD, Yumiko Sakurai, MSc, Wilbur A Lam, MD PhD

Blood (2015) 126 (23): 3381.

https://doi.org/10.1182/blood.V126.23.3381.3381

Published: 2015

Journal Articles

Improving Lentiviral Transduction Efficiency with Microfluidic Systems

Reginald Tran, BS, David R Myers, PhD, Jordan E Shields, MS, Byungwook Ahn, PhD, Yongzhi Qiu, PhD, Caroline Hansen, BS, Yumiko Sakurai, MSc, Robert Moot, BS, H. Trent Spencer, PhD, Christopher B Doering, PhD, Wilbur A Lam, MD PhD

Blood (2015) 126 (23): 4415.

https://doi.org/10.1182/blood.V126.23.4415.4415

Published: 2015

Journal Articles

Engineering a Valve-Regulated Endothelialized Microfluidic Device As an " in Vitro " Bleeding Time for Assessing Global Hemostasis

Yumiko Sakurai, MSc, Elaissa T. Hardy, PhD, Byungwook Ahn, PhD, Shannon L. Meeks, MD, W. Hunter Baldwin, BS, Shawn M Jobe, MD PhD, Wilbur A Lam, MD PhD

Blood (2015) 126 (23): 3485.

https://doi.org/10.1182/blood.V126.23.3485.3485

Published: 2015

Journal Articles

Commonly Used Clinical Intravenous Fluid Formulations Differentially Affect Sickle Red Blood Cell Stiffness and Transit Time

Marcus A Carden, MD, Meredith Ellen Fay, BS, Yumiko Sakurai, MSc, Robert G Mannino, BS, Jordan Ciciliano, BS, Reginald Tran, BS, Wilbur A Lam, MD PhD

Blood (2015) 126 (23): 2164.

https://doi.org/10.1182/blood.V126.23.2164.2164

Published: 2015

Journal Articles

Investigating Platelet Interactions in Sickle Cell Disease Using a Novel Multi-Shear "Endothelialized" Microfluidic System

Margo Renee Rollins, MD, Byungwook Ahn, PhD, Yumiko Sakurai, MSc, Jordan C Ciciliano, BS, Wilbur A Lam, MD PhD

Blood (2014) 124 (21): 4155.

https://doi.org/10.1182/blood.V124.21.4155.4155

Published: 2014

Journal Articles

“Self-Deposition” of Matrix Proteins from Platelet α-Granules Enable Extended Adhesion and Spreading on Micron/Submicron-Scale Fibrinogen and Collagen Substrates.

Yumiko Sakurai, MSc, Jennifer L Fitch-Tewfik, PhD, Yongzhi Qiu, PhD, David R Myers, PhD, Byungwook Ahn, PhD, Robert Flaumenhaft, MD/ PhD, Wilbur A Lam, MD PhD

Blood (2014) 124 (21): 2764.

https://doi.org/10.1182/blood.V124.21.2764.2764

Published: 2014

Journal Articles

Platelet Mechanosensing of Collagen Matrices

Matthew F Kee, Yongzhi Qiu, PhD, David R Myers, PhD, Yumiko Sakurai, MSc, Wilbur A Lam, MD PhD

Blood (2014) 124 (21): 1437.

https://doi.org/10.1182/blood.V124.21.1437.1437

Published: 2014

Journal Articles

Platelet Adhesion, Spreading and Activation Are Mediated By Mechanosensing of Matrix Stiffness

Yongzhi Qiu, PhD, Ashley C Brown, PhD, David R Myers, PhD, Yumiko Sakurai, MSc, Robert Mannino, BS, Reginald Tran, BS, Byungwook Ahn, PhD, Elaissa Hardy, PhD, Matthew F Kee, Sanjay Kumar, MD, PhD, Gang Bao, PhD, Thomas H Barker, PhD, Wilbur A Lam, MD PhD

Blood (2014) 124 (21): 1438.

https://doi.org/10.1182/blood.V124.21.1438.1438

Published: 2014

Journal Articles

New Insights Into The Mechanisms Of Ferric Chloride-Induced Thrombosis: a Reductionist Microfluidic Approach

Jordan C Ciciliano, BS, David R Myers, PhD, Meredith E Fay, Yumiko Sakurai, MSc, Renhao Li, PhD, Andrew Lyon, PhD, Wilbur A Lam, MD, PhD

Blood (2013) 122 (21): 2308.

https://doi.org/10.1182/blood.V122.21.2308.2308

Published: 2013

Journal Articles

An “Endothelialized” Microfluidic System That Distinguishes Procoagulant Mechanisms in Arterial and Venous Thrombosis

Byungwook Ahn, PhD, Yumiko Sakurai, MSc, David R Myers, PhD, Yongzhi Qiu, PhD, Elaissa Hardy, PhD, Reginald Tran, BS, Robert Mannino, Alisa S. Wolberg, PhD, Wilbur Lam, MD, PhD

Blood (2012) 120 (21): 1071.

https://doi.org/10.1182/blood.V120.21.1071.1071

Published: 2012

Journal Articles

Spatial Regulation of Platelet Aggregation and Physiology Under Flow

Reginald Tran, BS, Byungwook AHN, PhD, David R Myers, PhD, Yongzhi Qiu, PhD, Yumiko Sakurai, MSc

Blood (2012) 120 (21): 3300.

https://doi.org/10.1182/blood.V120.21.3300.3300

Published: 2012

Journal Articles

Platelet α-Granule Secretion and Cytoskeletal Rearrangements Are Spatially Regulated At the Micro/Nanoscale.

Yumiko Sakurai, MSc, Yongzhi Qiu, PhD, Byungwook Ahn, PhD, Wilbur Lam, MD, PhD

Blood (2012) 120 (21): 2163.

https://doi.org/10.1182/blood.V120.21.2163.2163

Published: 2012

Journal Articles

High-Throughput Nanomechanical Platelet Contraction Measurements Using Patterned Hydrogels.

David R Myers, PhD, Ashley C Brown, PhD, Yongzhi Qiu, PhD, Yumiko Sakurai, MSc, Reginald Tran, BS, Byungwook Ahn, PhD, Robert Mannino, Todd Sulchek, PhD, Andew Lyon, PhD, Thomas H Barker, PhD, Wilbur Lam, MD, PhD

Blood (2012) 120 (21): 2172.

https://doi.org/10.1182/blood.V120.21.2172.2172

Published: 2012

NARROW

Incorporating Hemoglobin Levels to Map Leukostasis Risk in Acute Leukemia Using Microvasculature-on-Chip Technologies

Monitoring the "Lifetime" of a Thrombus over Long Timescales By Leveraging a Novel Microvasculature-on-Chip Thrombosis Resolution Assay

Stiff Erythrocyte Subpopulations Biomechanically Induce Endothelial Inflammation in Sickle Cell Disease

A Comparative Medicine Study of Platelet Biophysics Among Hemostasis Models of Different Species

Mitochondrial Uncoupling Prevents Procoagulant Platelet Formation Resulting in Decreased Thrombus Stability

Leveraging the Contractile Force of Platelets for Targeted Factor VIII Delivery in Hemophilia with Inhibitors

Engineering a "Self-Healing" Hydrogel-Based Microvasculature-on-a-Chip for Investigating the Effects of Cellular and Biomolecular Interactions on Endothelial Permeability in Sickle Cell Disease

Characterizing Cellular Interactions Contributing to Vaso-Occlusion in Patients with Sickle Cell Disease Utilizing a Novel Endothelialized Microfluidic Device

Improving Lentiviral Transduction Efficiency with Microfluidic Systems

Engineering a Valve-Regulated Endothelialized Microfluidic Device As an " in Vitro " Bleeding Time for Assessing Global Hemostasis

Commonly Used Clinical Intravenous Fluid Formulations Differentially Affect Sickle Red Blood Cell Stiffness and Transit Time

Investigating Platelet Interactions in Sickle Cell Disease Using a Novel Multi-Shear "Endothelialized" Microfluidic System

“Self-Deposition” of Matrix Proteins from Platelet α-Granules Enable Extended Adhesion and Spreading on Micron/Submicron-Scale Fibrinogen and Collagen Substrates.

Platelet Mechanosensing of Collagen Matrices

Platelet Adhesion, Spreading and Activation Are Mediated By Mechanosensing of Matrix Stiffness

New Insights Into The Mechanisms Of Ferric Chloride-Induced Thrombosis: a Reductionist Microfluidic Approach

An “Endothelialized” Microfluidic System That Distinguishes Procoagulant Mechanisms in Arterial and Venous Thrombosis

Spatial Regulation of Platelet Aggregation and Physiology Under Flow

Platelet α-Granule Secretion and Cytoskeletal Rearrangements Are Spatially Regulated At the Micro/Nanoscale.

High-Throughput Nanomechanical Platelet Contraction Measurements Using Patterned Hydrogels.

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ASH Publications

American Society of Hematology

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ASH Publications

American Society of Hematology

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