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Journal Articles

HIF-1α Induces a Chemoresistance Phenotype in a Non-Hodgkin‘s Lymphoma Cell Line Via up-Regulation of Bcl- xL

Marco A Hernandez-Luna, M Sc, Leticia Rocha-Zavaleta, PhD, Mario I Vega, PhD, Sara Huerta-Yepez, PhD

Blood (2012) 120 (21): 5091.

https://doi.org/10.1182/blood.V120.21.5091.5091

Published: 2012

Journal Articles

Oxidative Stress Response and Cytotoxicity of Electrophilic Compounds in Primary Human Chronic Lymphocytic Leukemia.

Raymond P Wu, Ph.D., Tomoko Hayashi, M.D., Ph.D., Shiyin Yao, Christina C.N. Wu, Ph.D., Howard B Cottam, Ph.D., Michael Rosenbach, Richard B. Schwab, MD, Dennis A. Carson, MD

Blood (2009) 114 (22): 3444.

https://doi.org/10.1182/blood.V114.22.3444.3444

Published: 2009

Journal Articles

Identification of Core Gene Signature Associated with Synergism Between ABT-869, a FLT3 Inhibitor and SAHA, a HDAC Inhibitor in AML with FLT3-ITD Mutation.

Jianbiao Zhou, MD, MS, Chonglei Bi, Bsc, Shaw-Cheng Liu, Wee-Joo Chng, MD, Kian-Ghee Tay, Bsc, Hanry Yu, Ph.D., Keith Glaser, Ph.D., Daniel Albert, PhD, BSc, Steven K Davidsen, Ph.D., Chien-Shing Chen, MD, PhD

Blood (2008) 112 (11): 1618.

https://doi.org/10.1182/blood.V112.11.1618.1618

Published: 2008

Journal Articles

Mechanisms of 2-Methoxyestradiol-Induced Apoptosis on Myelodysplastic Syndrome MUTZ-1 Cell Lines.

Bao-An Chen, MD, PhD, Guo-Hua Xia, Hui-Xia Lu, Ze-Ye Shao, Chong Gao, Hua-Jia Ding, Ping-Pei Xiao, Ning-Na Chen, Gang Zhao, Feng Gao, Jian Chen, Jun Wang

Blood (2007) 110 (11): 4590.

https://doi.org/10.1182/blood.V110.11.4590.4590

Published: 2007

Journal Articles

ENMD-1198 in Combination with Vincristine Shows Synergistic Activity in Leukemia Cells and Prolonged Mouse Survival in Human Leukemia Xenografts.

Tracy T.Y.E. Liaw, BSci(Hons), Patricia P.A. Burke, PhD, X. Chen, PhD, Theresa T.M. LaVallee, PhD, Richard Lock, PhD, Maria Kavallaris, PhD

Blood (2007) 110 (11): 859.

https://doi.org/10.1182/blood.V110.11.859.859

Published: 2007

Journal Articles

Integrated molecular profiling of SOD2 expression in multiple myeloma

Elaine M. Hurt, Suneetha B. Thomas, Benjamin Peng, William L. Farrar

Blood (2006) 109 (9): 3953–3962.

https://doi.org/10.1182/blood-2006-07-035162

Published: 2006

Includes: Supplemental data

Journal Articles

2-Methoxyestradiol in Combination with Velcade® Results in an Augmentation of NFκB Inhibition, In Vitro Antiproliferative Activity and In Vivo Antitumor Efficacy in the RPMI-8226 Myeloma Model.

Patricia Burke, PhD, Glenn M. Swartz, B.S., Cassandra L. Waters, B.S., Xiaoru Chen, M.D., Theresa M. LaVallee, Ph.D., Anthony M. Treston, Ph.D., William E. Fogler, Ph.D., Carolyn F. Sidor, MD

Blood (2006) 108 (11): 3521.

https://doi.org/10.1182/blood.V108.11.3521.3521

Published: 2006

Journal Articles

2-Methoxyestradiol Sensitizes B-NHL Cells to TRAIL-Mediated Apoptosis Via Inhibition of HIF-1α, NF-κ B, YY1 and Induction of DR5 Expression.

Sara Huerta-Yepez, PhD, Mario I. Vega, Ph.D., Stavroula Baritaki, Ph.D., Eriko Suzuki, Theresa La Vallee, Ph.D., Benjamin Bonavida, Ph.D.

Blood (2006) 108 (11): 4642.

https://doi.org/10.1182/blood.V108.11.4642.4642

Published: 2006

Journal Articles

The Requirement of Reactive Oxygen Species Generation in the Apoptosis of Leukemia Cells Induced by 2-Methoxyestradiol.

Guo Kunyuan, MD, Miaorong She, MD, Haiyan Hu, MD, Xinqing Niu, MD, Sanfang Tu, MD, Xiaoxun Lu, MD

Blood (2006) 108 (11): 4370.

https://doi.org/10.1182/blood.V108.11.4370.4370

Published: 2006

Journal Articles

Polydeoxyribonucleotides Antagonize Nucleoside Analogues in Cancer Therapy.

Ting Yang, MD, Ingo Steinmann, MD, Simone Tank, Zhizhe Chen, Hans-Jochem Kolb, Raymund Buhmann, MD

Blood (2006) 108 (11): 4383.

https://doi.org/10.1182/blood.V108.11.4383.4383

Published: 2006

Journal Articles

Synergistic antileukemic interactions between 2-medroxyestradiol (2-ME) and histone deacetylase inhibitors involve Akt down-regulation and oxidative stress

Ning Gao, Mohamed Rahmani, Xianglin Shi, Paul Dent, Steven Grant

Blood (2006) 107 (1): 241–249.

https://doi.org/10.1182/blood-2005-06-2409

Published: 2006

Journal Articles

2-Methoxyestradiol Is Exclusively Effective on Both Retinoic Acid-Sensitive and -Resistant Acute Promyelocytic Leukemia through the Inhibition of NF-κB.

Ming-jer Huang, MD, Yunchi Cheng, MS, Shufan Lin, MS, Zhilone Chen, BS, Hsingjin E. Liu, MD, PhD

Blood (2005) 106 (11): 4434.

https://doi.org/10.1182/blood.V106.11.4434.4434

Published: 2005

Journal Articles

Role of HIF as a Growth and Survival Factor in Multiple Myeloma.

Rena Feinman, PhD, Billy Abungu, BSc, Dimitrios Barlos, MD

Blood (2005) 106 (11): 3419.

https://doi.org/10.1182/blood.V106.11.3419.3419

Published: 2005

Journal Articles

Chemosensitization of Drug-Resistant Ramos B-NHL to Drug-Induced Apoptosis: YY1 Expression Is Decreased in Response to Cytoskeletal-Interacting Drugs.

Mehran Neshat, PhD, Ali R. Jazirehi, PhD, Benjamin Bonavida, PhD

Blood (2005) 106 (11): 4806.

https://doi.org/10.1182/blood.V106.11.4806.4806

Published: 2005

Journal Articles

Apoptosis of Proliferating Endothelial Cells Induced by Cleaved High Molecular Weight Kininogen (HKa) Involves an Oxidation-Dependent Pathway.

Danyu Sun, Ph.D., Keith McCrae, M.D.

Blood (2004) 104 (11): 3926.

https://doi.org/10.1182/blood.V104.11.3926.3926

Published: 2004

Journal Articles

2-Methoxyestradiol alters cell motility, migration, and adhesion

Martin Sattler, Laura R. Quinnan, Yuri B. Pride, Jessica L. Gramlich, Stephanie C. Chu, Gaelle C. Even, Stine-Katherin Kraeft, Lan Bo Chen, Ravi Salgia

Blood (2003) 102 (1): 289–296.

https://doi.org/10.1182/blood-2002-03-0729

Published: 2003

Journal Articles

Free radical stress in chronic lymphocytic leukemia cells and its role in cellular sensitivity to ROS-generating anticancer agents

Yan Zhou, Elizabeth O. Hileman, William Plunkett, Michael J. Keating, Peng Huang

Blood (2003) 101 (10): 4098–4104.

https://doi.org/10.1182/blood-2002-08-2512

Published: 2003

Journal Articles

Identification of genes regulated by 2-methoxyestradiol (2ME2) in multiple myeloma cells using oligonucleotide arrays

Dharminder Chauhan, Guilan Li, Daniel Auclair, Teru Hideshima, Paul Richardson, Klaus Podar, Nicholas Mitsiades, Constantine Mitsiades, Cheng Li, Ryung Suk Kim, Nikhil Munshi, Lan Bo Chen, Wing Wong, Kenneth C. Anderson

Blood (2003) 101 (9): 3606–3614.

https://doi.org/10.1182/blood-2002-10-3146

Published: 2003

Journal Articles

2-Methoxyestradiol overcomes drug resistance in multiple myeloma cells

Dharminder Chauhan, Laurence Catley, Teru Hideshima, Guilan Li, Richard Leblanc, Deepak Gupta, Martin Sattler, Paul Richardson, Robert L. Schlossman, Klaus Podar, Edie Weller, Nikhil Munshi, Kenneth C. Anderson

Blood (2002) 100 (6): 2187–2194.

https://doi.org/10.1182/blood-2002-02-0376

Published: 2002

Journal Articles

Control of Cell Cycle Progression in Human Natural Killer Cells Through Redox Regulation of Expression and Phosphorylation of Retinoblastoma Gene Product Protein

Akira Yamauchi, Eda T. Bloom

Blood (1997) 89 (11): 4092–4099.

https://doi.org/10.1182/blood.V89.11.4092

Published: 1997

NARROW

HIF-1α Induces a Chemoresistance Phenotype in a Non-Hodgkin‘s Lymphoma Cell Line Via up-Regulation of Bcl- xL

Oxidative Stress Response and Cytotoxicity of Electrophilic Compounds in Primary Human Chronic Lymphocytic Leukemia.

Identification of Core Gene Signature Associated with Synergism Between ABT-869, a FLT3 Inhibitor and SAHA, a HDAC Inhibitor in AML with FLT3-ITD Mutation.

Mechanisms of 2-Methoxyestradiol-Induced Apoptosis on Myelodysplastic Syndrome MUTZ-1 Cell Lines.

ENMD-1198 in Combination with Vincristine Shows Synergistic Activity in Leukemia Cells and Prolonged Mouse Survival in Human Leukemia Xenografts.

Integrated molecular profiling of SOD2 expression in multiple myeloma

2-Methoxyestradiol in Combination with Velcade® Results in an Augmentation of NFκB Inhibition, In Vitro Antiproliferative Activity and In Vivo Antitumor Efficacy in the RPMI-8226 Myeloma Model.

2-Methoxyestradiol Sensitizes B-NHL Cells to TRAIL-Mediated Apoptosis Via Inhibition of HIF-1α, NF-κ B, YY1 and Induction of DR5 Expression.

The Requirement of Reactive Oxygen Species Generation in the Apoptosis of Leukemia Cells Induced by 2-Methoxyestradiol.

Polydeoxyribonucleotides Antagonize Nucleoside Analogues in Cancer Therapy.

Synergistic antileukemic interactions between 2-medroxyestradiol (2-ME) and histone deacetylase inhibitors involve Akt down-regulation and oxidative stress

2-Methoxyestradiol Is Exclusively Effective on Both Retinoic Acid-Sensitive and -Resistant Acute Promyelocytic Leukemia through the Inhibition of NF-κB.

Role of HIF as a Growth and Survival Factor in Multiple Myeloma.

Chemosensitization of Drug-Resistant Ramos B-NHL to Drug-Induced Apoptosis: YY1 Expression Is Decreased in Response to Cytoskeletal-Interacting Drugs.

Apoptosis of Proliferating Endothelial Cells Induced by Cleaved High Molecular Weight Kininogen (HKa) Involves an Oxidation-Dependent Pathway.

2-Methoxyestradiol alters cell motility, migration, and adhesion

Free radical stress in chronic lymphocytic leukemia cells and its role in cellular sensitivity to ROS-generating anticancer agents

Identification of genes regulated by 2-methoxyestradiol (2ME2) in multiple myeloma cells using oligonucleotide arrays

2-Methoxyestradiol overcomes drug resistance in multiple myeloma cells

Control of Cell Cycle Progression in Human Natural Killer Cells Through Redox Regulation of Expression and Phosphorylation of Retinoblastoma Gene Product Protein

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American Society of Hematology

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American Society of Hematology

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