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Journal Articles

Preclinical Evaluation of ALLO-819, an Allogeneic CAR T Cell Therapy Targeting FLT3 for the Treatment of Acute Myeloid Leukemia

Free
Cesar Sommer, PhD, Hsin-Yuan Cheng, PhD, Yik Andy Yeung, PhD, Duy Nguyen, Janette Sutton, Zea Melton, Julien Valton, PhD, Kris Poulsen, Ivana Djuretic, PhD, Thomas Van Blarcom, PhD, Javier Chaparro-Riggers, PhD, Barbra Sasu, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3921.
https://doi.org/10.1182/blood-2019-129025
Published: 2019
Journal Articles

Retrospective Review of Patients with Large Granular Lymphocyte (LGL) Leukemia in a Single Institution over a Period of 11 Years

Free
Kulsum Bano, MD, Manojna Konda, MD, Dinesh Atwal, MD, Richa Parikh, MD, Aneesha Ananthula, MD, Anusha Jillella, MD, Aasiya Matin, MD, Appalanaidu Sasapu, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 5279.
https://doi.org/10.1182/blood-2019-131352
Published: 2019
Journal Articles

A Case Report of the Benefit of Cannabidiol (Cannabidiol (CBD)-Predominant Medical Cannabis Preparation) in the Management of Refractory Skin Graft Vs Host Disease (GVHD)

Free
Tsiporah B. Shore, MD, Jessy B. Ryan, ANP, Michael B. Samuel, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 5687.
https://doi.org/10.1182/blood-2019-122715
Published: 2019
Journal Articles

Post Allograft Rituximab Responsive Cytopenia (RRC)

Free
Samar Kulkarni, MD, John Murray, RGN, MSc, David Kaye, MSc, Michael Dennis, FRCPath, Anna Castleton, FRCPath, Mohd K Mamat, MRCP, James Cavet, Daniel Wiseman, FRCPath, Tim Somervaille, FRCPath, Sven Sommerfeld, MRCP, Richard Chasty, FRCPath, Adrian Bloor, FRCPath
Journal: Blood
Blood (2019) 134 (Supplement_1): 5645.
https://doi.org/10.1182/blood-2019-132214
Published: 2019
Journal Articles

An Update of Australasian Trends in Allogeneic Stem Cell Transplantation for Myelofibrosis in the Molecular Era

Free
Yadanar Lwin, MBBS, MMed(InfnImm), FRACP, FRCPA, Simon Zhao-Xiong He, MBBS,FRACP,FRCPA, Andrew Spencer, MBBS, FRACP, FRCPA, DM, Duncan Purtill, MBBS,FRCPA,FRACP, Ashley Mcewan, MBBS, Peter Browett, BMedSci, MBChB, FRACP, FRCPA, Andrew Butler, MB ChB(Edin), MRCP, MRCPath, John Carter, BMedSc MBChB FRACP FRCPA, Peter G Bardy, MBBS, FRACP, FRCPA, FRCPath, Glen A Kennedy, MBBS FRACP FRCPA, Jeffrey Szer, MBBS, David Ritchie, MD PhD, Matthew Greenwood, MBBS, FRACP, FRCPA, Stephen R Larsen, MBBS, PhD FRACP, FRCPA, Sam Milliken, MBBS, FRACP, FRCPA, Hock Choong Lai, MBBS, FRACP, FRCPA, David Gottlieb, MBBS, MD FRACP, FRCPA, John Kwan, MBBS,FRACP,FRCPA, Donna Aarons, Steven Tran, Nada Hamad, MBBS,BSc,MSc,FRACP FRCPA
Journal: Blood
Blood (2019) 134 (Supplement_1): 5719.
https://doi.org/10.1182/blood-2019-126547
Published: 2019
Journal Articles

Oral Fludarabine and Intravenous Rituximab (FR) for Chronic Lymphocytic Leukemia (CLL): Long Term Outcomes and Secondary Malignancies in 673 Patients Treated in British Columbia (BC)

Free
Elysha Vanderveer, MD BSc, Steven J.T. Huang, BMLSc, Helene Bruyere, MD FCCMG, Tanya Gillan, PhD FCCMG, Charles H. Li, MDFRCPC, Khaled Ramadan, MBBCH, MRCP, FRCPath, Diego Villa, MD MPH, David W. Scott, MBChB, PhD, Kerry J Savage, BSc, MD MSc, Joseph M Connors, MD, Laurie H Sehn, MD, Cynthia L Toze, MD FRCPC, Alina S Gerrie, MD MPH
Journal: Blood
Blood (2019) 134 (Supplement_1): 4300.
https://doi.org/10.1182/blood-2019-125189
Published: 2019
Journal Articles

Phenotypic Characterization of Leukemia-Initiating Stem Cells in Chronic Myelomonocytic Leukemia (CMML)

Free
Gregor Eisenwort, MD PhD, Alexandra Keller, Michael Willmann, Irina Sadovnik, Greiner Georg, MD PhD, Karoline V. Gleixner, MD, Daniel Ivanov, MSc, Daniela Berger, Gabriele Stefanzl, Christiana Winding, DVM, Gregor Hoermann, Wolfgang R. Sperr, MD, Heinz Sill, MD, Peter Bettelheim, MD, Klaus Geissler, MD, Michael W. Deininger, Thomas Rülicke, Peter Valent, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 4223.
https://doi.org/10.1182/blood-2019-122530
Published: 2019
Journal Articles

Subcutaneous Alemtuzumab Has Activity in Treatment-Naïve Patients with Acquired Aplastic Anemia

Free
Ana Rita Da Fonseca, MD, Anita Hill, MD PhD, Patricia Eiko Yamakawa, MD, Iara Baldim Rabelo, MD PhD, Andre Domingues Pereira, MD, Vinicius Campos de Molla, MD, Matheus Vescovi Gonçalves, MD PhD, Morag Griffin, MD, Talha Munir, MD, Peter Hillmen, MD PhD, Louise Arnold, MD, Kathryn Riley, MD, Antonio M. Risitano, MD PhD, Phillip Scheinberg, MD, Celso Arrais-Rodrigues, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2503.
https://doi.org/10.1182/blood-2019-130719
Published: 2019
Journal Articles

Combination of Venetoclax and Ibrutinib Increases bcl2-Dependent Apoptotic Priming, Reduces ITK-Phosphorylation and Is Clinically Promising in Relapsed/Refractory T-Prolymphocytic Leukemia

Free
Christoph Kornauth, Charles Herbaux, MD MSc, Bernd Boidol, PhD, Chantal Guillemette, Patrick Caron, Stéphanie Poulain, MD PhD, Olivier Tournilhac, Marius E Mayerhoefer, Ulrich Jaeger, MD, Stefan Kubicek, Matthew S. Davids, MD, Philipp Bernhard Staber, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3965.
https://doi.org/10.1182/blood-2019-124392
Published: 2019
Journal Articles

Phase 2 Study of Alemtuzumab Added to Dose-Adjusted EPOCH-R in Relapsed and Refractory Aggressive B-Cell Lymphomas

Free
Sanjal Desai, MD, Christopher Melani, MD, Kieron Dunleavy, MD, Stefania Pittaluga, MD PhD, Mark A. Ahlman, MD, Andrea Nicole Lucas, RN, Seth M. Steinberg, PhD, Elaine S. Jaffe, MD, Mark Roschewski, MD, Wyndham Wilson, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 4102.
https://doi.org/10.1182/blood-2019-127481
Published: 2019
Journal Articles

Alemtuzumab as First Line Treatment in Children with Familial Lymphohistiocytosis

Free
Despina Moshous, MD PhD, Coralie Briand, MD, Martin Castelle, MD, Laurent Dupic, MD, Guillaume Morelle, MD, Wadih Abou Chahla, MD, Vincent Barlogis, MD PhD, Yves Bertrand, MD, Bénédicte Bruno, MD, Eric Jeziorski, MD PhD, Catherine Paillard, MD PhD, Pierre Simon Rohrlich, MD PhD, Jean Louis Stephan, MD PhD, Caroline Thomas, MD, Stéphanie Chhun, PharmD, PhD, Isabelle Pellier, MD PhD, Aude Marie-Cardine, MD, Mathieu Fusaro, Genevieve de Saint Basile, MD PhD, Capucine Picard, MD PhD, Caroline Elie, MD PhD, Benedicte Neven, MD PhD, Stephane Blanche, MD, Alain Fischer, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 80.
https://doi.org/10.1182/blood-2019-124477
Published: 2019
Journal Articles

First-in-Human CD4 CAR Clinical Trial on Peripheral T-Cell Lymphoma

Free
Hongyu Zhang, MD PhD, Jia Feng, MD PhD, Wenli Zhang, MD, Qi Chen, PhD, Yuanzhen Cao, Kevin Pinz, Fang Liu, MD PhD, Yu Ma, Masayuki Wada, PhD, Yupo Ma, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2881.
https://doi.org/10.1182/blood-2019-122789
Published: 2019
Journal Articles

Feasibility and Outcomes of T-Cell Depleted Hematopoietic Stem Cell Transplantation in Patients with Relapsed or Refractory AML and High Risk MDS

Free
Satyajit Kosuri, MD, Sang Mee Lee, PhD, Hongtao Liu, MD PhD, Mylove Mortel, MS, RN, Lucy A Godley, MD PhD, Richard A. Larson, MD, Olatoyosi Odenike, MD, Wendy Stock, MD, Justin Kline, MD, Peter A. Riedell, MD, Koen Van Besien, MD PhD, Michael R. Bishop, MD, Andrew S. Artz, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3324.
https://doi.org/10.1182/blood-2019-126211
Published: 2019
Journal Articles

Allogeneic Anti-CD19 CAR T Cells Manufactured from Healthy Donors Provide a Unique Cellular Product with Distinct Phenotypic Characteristics Compared to CAR T Cells Generated from Patients with Mature B Cell Malignancies

Free
Charlotte Graham, MRCP, BSc, MBBS, Agnieszka Jozwik, PhD, Ruby Quartey-Papafio, Nikolaos Ioannou, PhD MSc, BSc, Ana M Metelo, PhD, Carlo Scala, PhD, Glenda Dickson, PhD, Orla Stewart, Maria Almena-Carrasco, Elisa Peranzoni, Alan G. Ramsay, BSc,MSc,PhD, Sandra Dupouy, Pharm.D, PhD, Farzin Farzaneh, PhD, Piers E.M. Patten, BSc, MRCP, MRCPath, PhD, Andrea Pepper, PhD, Reuben Benjamin, FRCPath, MRCP, MBBS, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3228.
https://doi.org/10.1182/blood-2019-123018
Published: 2019
Journal Articles

Incorporation of Thiotepa in a Reduced Intensity Conditioning Regimen Leads to Improved Engraftment after Stem Cell Transplant for Patients with Hemophagocytic Lymphohistiocytosis

Free
Swati Naik, MBBS, Olive S. Eckstein, MD, Ghadir Sasa, MD, Robert A. Krance, MD, Carl E. Allen, MD PhD, Helen E. Heslop, MD DSc, Caridad A. Martinez, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3273.
https://doi.org/10.1182/blood-2019-132120
Published: 2019
Journal Articles

Role of Disease Mechanism in Hematopoietic Cell Transplantation Outcomes for Hemophagocytic Lymphohistiocytosis

Free
Aleksandra S. Dain, MD, Michelle L. Hermiston, MD PhD, Kristin A. Shimano, MD, Sandhya Kharbanda, MD, Alexis Melton, MD PhD, Jasmeen Dara, MD, James N Huang, MD, Christopher C. Dvorak, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3343.
https://doi.org/10.1182/blood-2019-127397
Published: 2019
Journal Articles

Universal' Fratricide-Resistant CAR T Cells Against T Cell Leukemia Generated By Coupled & Uncoupled Deamination Mediated Base Editing

Free
Christos Georgiadis, PhD, Jane Rasaiyaah, PhD, Soragia Athina Gkazi, PhD, Roland Preece, Annie Etuk, PhD, Abraham Christi, Waseem Qasim, MBBS, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3219.
https://doi.org/10.1182/blood-2019-130057
Published: 2019
Journal Articles

Antibody-Associated Autoimmune Disease (AAD) in Children with Cancer in Immune Recovery Phase Following Cessation of Chemotherapy

Free
Akihiro Iguchi, MD PhD, Kazuya Hara, MD, Yukayo Terashita, MD, Minako Sugiyama, MD, Yuko Cho, MD, Atsushi Manabe, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1052.
https://doi.org/10.1182/blood-2019-123015
Published: 2019
Journal Articles

Differential Alemtuzumab Dosage Effects in T-Cell Deplete Allogeneic Haematopoietic Stem Cell Transplants for Myeloid Malignancies- King's College Hospital London Experience

Free
Varun Mehra, MBBS,MRCP,FRCPath, Daniele Avenoso, MD, Ximena Cabrera Castellano, Adrian Choy, Stefani Widya, Mili Shah, FRCPath, Shafqat Inam, MD, Shreyans Gandhi, MBBS,MDDNB,MRCP,FRCPath,MPhil, Austin Kulasekararaj, MD MRCP, FRCPath, Francesco Dazzi, PhD, Ghulam J. Mufti, MBBS, FRCP, FRCPath, DM, Antonio Pagliuca, MBBS, MA, FRCP, FRCPath, Hugues De Lavallade, Victoria Potter, MBBS, BSc, FRACP, FRCPA
Journal: Blood
Blood (2019) 134 (Supplement_1): 4622.
https://doi.org/10.1182/blood-2019-131239
Published: 2019
Journal Articles

T-Cell Reconstitution after Unrelated Donor HSCT Using Immunotherapy with CD25/71 Allodepleted Donor T Cells: Results of the Randomised Icat Study

Free
Karl S Peggs, Sarah J Albon, MSc, Catherine Irving, BSc, Rachel Richardson, MSc, Joan Casanovas-Company, Rebecca Wallace, Aleks Guvenel, PhD, Sara Ghorashian, FRCPath, PhD, Angela Collura, Meera Subramaniyam, Barry Flutter, Bilyana Popova, Fernanda Castro, Andre Lopes, Kim Champion, Oliver Schofield, Laura Clifton-Hadley, PhDBSc, Thomas Taylor, Timothy Pulham, BSc, MPhil, Stuart Ings, Robert Herlihy, Maria Farrell, Rachael Wilding, Wendy Ogden, Stuart Adams, PhD, Gulrukh Ahsan, Kimberly C Gilmour, Stephen Mackinnon, MD, Eleni Tholouli, MD MRCPath, Persis J Amrolia, FRCP, FRCPath, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1995.
https://doi.org/10.1182/blood-2019-124404
Published: 2019