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Journal Articles

ROR1 Targeted Immunoliposomal Delivery of OSU-2S Show Selective Cytotoxicity in t(1;19) Translocated B-ALL

Swagata Goswami, MSc, Chi-Ling Chiang, PhD, Kevan Zapolnik, BS, Zhiliang Xie, James L. Lee, PhD, Sivasubramanian Baskar, Christoph Rader, PhD, John C. Byrd, MD, Mitch A. Phelps, PhD, Bhavana Bhatnagar, DO, Natarajan Muthusamy, DVM,PhD

Blood (2019) 134 (Supplement_1): 3798.

https://doi.org/10.1182/blood-2019-128828

Published: 2019

Journal Articles

High Mobility Group A1 Chromatin Regulators Function As Critical Drivers of Leukemogenesis in Preclinical Models of Relapsed, Pediatric B-Cell ALL

Liping Li, MD PhD, Katharina Hayer, Lingling Xian, MD PhD, Li Luo, PhD, Leslie Cope, Andrei Thomas-Tikhonenko, PhD, Linda Resar, MD

Blood (2019) 134 (Supplement_1): 3946.

https://doi.org/10.1182/blood-2019-130261

Published: 2019

Journal Articles

Targeting WNT10B-Driven Signalling through Induction of FZD6 By Porcupine Inhibition in T Cell Acute Lymphoblastic Leukemia

Adriana Cassaro, PhD, Francesca Lazzaroni, Dr, Giovanni Grillo, MD, Gianluigi Reda, MD, Roberto Cairoli, MD, Alessandro Beghini

Blood (2019) 134 (Supplement_1): 3956.

https://doi.org/10.1182/blood-2019-124871

Published: 2019

Journal Articles

Loss of Gpr68 Enhances Hematopoietic Stem Cell Function during Aging

Xiaofei He, B.S., Caleb Hawkins, B.S., Lauren Lawley, B.S., Yan Xu, PhD, Xiang-ming Zha, PhD, Jing Fang, MD PhD

Blood (2019) 134 (Supplement_1): 3719.

https://doi.org/10.1182/blood-2019-125168

Published: 2019

Journal Articles

Synergistic Targeting of BTK and E-Selectin/CXCR4 in the Microenvironment of Mantle Cell Lymphomas

Mahesh Basyal, Weiguo Zhang, MD PhD, Nalini B Patel, Sujan Piya, PhD, Hongying Zhang, MD PhD, William E. Fogler, PhD, William G Rice, PhD, John L. Magnani, PhD, Gautam M. Borthakur, MD, Michael Andreeff, MD PhD

Blood (2019) 134 (Supplement_1): 3802.

https://doi.org/10.1182/blood-2019-126030

Published: 2019

Journal Articles

Mn Porphyrin-Based Redox Active Drugs Improve Anemia and Reduce Organ Damage in a Murine Model of Sickle Cell Disease

Madhan Thamilarasan, PhD, Rodolfo Estupinan, Rahima Zennadi, PhD

Blood (2019) 134 (Supplement_1): 2255.

https://doi.org/10.1182/blood-2019-131140

Published: 2019

Journal Articles

Modeling the Behavior of Hematopoietic Compartments from Stem to Red Cells in Murine Steady State and Stress Hematopoiesis

Celine Bonnet, BSc, Panhong Gou, BSc, Vincent Bensaye, PhD Associate Professor, Catherine Lacout, Ingeneer, Karine Bailly, Ingeneer, Marie-helene Schlagetter, MD PhD, Evelyne Lauret, PhD, Sylvie Meleard, PhD Professor, Stephane Giraudier, MD PhD

Blood (2019) 134 (Supplement_1): 2224.

https://doi.org/10.1182/blood-2019-123704

Published: 2019

Journal Articles

Procoagulant Microparticles Derived from Myeloma Plasma Cells Have a Determinant Role in the Hypercoagulable State Associated with Multiple Myeloma. a Modelization in Vitro Study

Loula Papageorgiou, Patrick Van Dreden, PhD, Meletios A. Dimopoulos, MD, Annette Larsen, Mohamad Mohty, MD PhD, Ismail Elalamy, MD PhD, Grigorios T. Gerotziafas

Blood (2019) 134 (Supplement_1): 2425.

https://doi.org/10.1182/blood-2019-124650

Published: 2019

Journal Articles

Protein Cysteine Sulfenylation By CD36-Dependent Reactive Oxygen Species Signaling Promotes Platelet Activation

Moua Yang, PhD, Calvin Harberg, Wenjing Chen, Sarah L. Wynia-Smith, PhD, Kate S. Carroll, PhD, Jacek Zielonka, PhD, Roy L. Silverstein, MD, Brian C. Smith, PhD

Blood (2019) 134 (Supplement_1): 2338.

https://doi.org/10.1182/blood-2019-122465

Published: 2019

Journal Articles

Curcumin Enhances the Sensitivity of Bortezomib By Inhibiting NF-Κb in ABC Diffuse Large B-Cell Lymphoma Cells

Xiaolei Wei, PhD, Jialin Song, Yongqiang Wei, PhD, Hong Zeng, Weimin Huang, PhD, Jingxia Zheng, Ru Feng, MD

Blood (2019) 134 (Supplement_1): 5237.

https://doi.org/10.1182/blood-2019-127705

Published: 2019

Journal Articles

Combination of Tigecycline and Homoharringtonine Synergistically Enhances Anti-Leukemia and Anti-MDS Effect Followed By Inhibiting Mitochondrial Translation through AKT/Mtorpathway and Downregulation of Anti-Apoptotic Proteins

Jie Jin, MD PhD, Hongyan Tong, Yang Haiyang

Blood (2019) 134 (Supplement_1): 5387.

https://doi.org/10.1182/blood-2019-128171

Published: 2019

Journal Articles

MCL-1 Inhibition By the Selective MCL-1 Inhibitor AMG-176 Induces in Vitro Activity Against Burkitt Lymphoma Cell Lines and Synergistically Enhances the Cytotoxic Effect of Chemotherapy and BH3 Mimetics

Tara Daly, BS, Thomas Ippolito, MSc, Juan J. Gu, MD PhD, Cory Mavis, MSc, Pallawi Torka, MD, Francisco J. Hernandez-Ilizaliturri, MD, Matthew J. Barth, MD

Blood (2019) 134 (Supplement_1): 5303.

https://doi.org/10.1182/blood-2019-129052

Published: 2019

Journal Articles

SHC014748M, a Novel Selective Inhibitor of PI3Kδ, Demonstrates Promising Pre-Clinical Antitumor Activity in B Cell Lymphomas and CLL

Lei Fan, MD PhD, Chao Wang, Zhiqiang Wang, Xian Zhang, Lei Cao, Yi Miao, MD PhD, Xinyi Du, Wei Xu, MD PhD, Jianyong Li, MD

Blood (2019) 134 (Supplement_1): 5306.

https://doi.org/10.1182/blood-2019-129469

Published: 2019

Journal Articles

ROR1 Small Molecule Inhibitor (KAN0441571C) Induced Significant Apoptosis of Mantle Cell Lymphoma (MCL) Cells

Håkan Mellstedt, MD PhD Prof., Amineh Ghaderi, MSc, Johanna Aschan, MSc, Fariba Mozaffari, MSc,PhD, Ali Moshfegh, MSc,PhD, Birgitta Sander, MD PhD Prof., Johan Schultz, MSc,PhD, Martin Norin, MSc,PhD, Thomas Olin, MSc,PhD, Elias Drakos, MD PhD Prof., George Z. Rassidakis, MD PhD Prof., Anders Österborg, MD PhD, Mohammad Hojjat-Farsangi, MSc,PhD

Blood (2019) 134 (Supplement_1): 5312.

https://doi.org/10.1182/blood-2019-129773

Published: 2019

Journal Articles

C-Myc-Driven and PRMT5-Dependent Regulation of Multiple Myeloma Cell Proliferation through TNRC6B Gene

Peipei Xu, Guo Dan, Bing Chen, PhD, Quan Zhao, Rong-Fu Zhou, Prof., Jian Ouyang

Blood (2019) 134 (Supplement_1): 5520.

https://doi.org/10.1182/blood-2019-125027

Published: 2019

Journal Articles

Identification of Deubiquitinase OTUD1 As a Novel Player in Resistance of Multiple Myeloma to Bortezomib

Alexander Vdovin, Tomas Jelinek, MD, Matous Hrdinka, PhD, Juli R. Bago, PhD, Tereza Sevcikova, Roman Hajek, Prof, MD PhD, Michal Simicek, PhD

Blood (2019) 134 (Supplement_1): 5526.

https://doi.org/10.1182/blood-2019-127930

Published: 2019

Journal Articles

In Systemic Masocytosis, Midostaurin Targets Both Kit and Aurora Kinase a Reverting H3K36Me3 Deficiency and Synergizes with Second-Generation Tyrosine Kinase Inhibitors

Blood (2019) 134 (Supplement_1): 4204.

https://doi.org/10.1182/blood-2019-126538

Published: 2019

Journal Articles

S100A9 Contributes to T Cell Dysfunction through Its Interaction with RAGE in MDS

Wendy Kandell, BS, Thu Le Trinh, PhD, Xianghong Chen, PhD, Pingyan Cheng, MD, Danielle Gilvary, BS, Yin-Kai Chen, MD, Alexandra Calescibetta, Erika Adriana Eksioglu, MS PhD, Alan F. List, MD, Sheng Wei, MD

Blood (2019) 134 (Supplement_1): 4228.

https://doi.org/10.1182/blood-2019-128717

Published: 2019

Journal Articles

Dose-Dependent Iron Chelating Effects of Eltrombopag on in Vitro Human Megakaryopoiesis

Zhi-Jian Liu, PhD, Emoke Deschmann, MD, Haley E. Ramsey, PhDMSc, Henry Feldman, Bethan Psaila, MD PhD, Nichola Cooper, MD MRCP, Evangelia Vlachodimtropoulou Koumoutsea, MBBS,PhDBSc, John B. Porter, MA MDFRCP FRCPath, James B. Bussel, MD, Michael Georgieff, MD, Martha Sola-Visner, MD

Blood (2019) 134 (Supplement_1): 2475.

https://doi.org/10.1182/blood-2019-131895

Published: 2019

Journal Articles

DNA Cytosine-Demethylating Agent 5-Aza-2'-Deoxycytidine Targets Leukemia Cells through Reducing DNA N 6 -Methyladenine

Xiaochang Liu, PhD, Jiuxia Pang, Christopher Seiler, Ryan Kempen, Hao Liu, Aref Al-Kali, MD, Y. Natalia Tretyakova, Mark Litzow, MD, Shujun Liu

Blood (2019) 134 (Supplement_1): 2513.

https://doi.org/10.1182/blood-2019-130490

Published: 2019

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ROR1 Targeted Immunoliposomal Delivery of OSU-2S Show Selective Cytotoxicity in t(1;19) Translocated B-ALL

High Mobility Group A1 Chromatin Regulators Function As Critical Drivers of Leukemogenesis in Preclinical Models of Relapsed, Pediatric B-Cell ALL

Targeting WNT10B-Driven Signalling through Induction of FZD6 By Porcupine Inhibition in T Cell Acute Lymphoblastic Leukemia

Loss of Gpr68 Enhances Hematopoietic Stem Cell Function during Aging

Synergistic Targeting of BTK and E-Selectin/CXCR4 in the Microenvironment of Mantle Cell Lymphomas

Mn Porphyrin-Based Redox Active Drugs Improve Anemia and Reduce Organ Damage in a Murine Model of Sickle Cell Disease

Modeling the Behavior of Hematopoietic Compartments from Stem to Red Cells in Murine Steady State and Stress Hematopoiesis

Procoagulant Microparticles Derived from Myeloma Plasma Cells Have a Determinant Role in the Hypercoagulable State Associated with Multiple Myeloma. a Modelization in Vitro Study

Protein Cysteine Sulfenylation By CD36-Dependent Reactive Oxygen Species Signaling Promotes Platelet Activation

Curcumin Enhances the Sensitivity of Bortezomib By Inhibiting NF-Κb in ABC Diffuse Large B-Cell Lymphoma Cells

Combination of Tigecycline and Homoharringtonine Synergistically Enhances Anti-Leukemia and Anti-MDS Effect Followed By Inhibiting Mitochondrial Translation through AKT/Mtorpathway and Downregulation of Anti-Apoptotic Proteins

MCL-1 Inhibition By the Selective MCL-1 Inhibitor AMG-176 Induces in Vitro Activity Against Burkitt Lymphoma Cell Lines and Synergistically Enhances the Cytotoxic Effect of Chemotherapy and BH3 Mimetics

SHC014748M, a Novel Selective Inhibitor of PI3Kδ, Demonstrates Promising Pre-Clinical Antitumor Activity in B Cell Lymphomas and CLL

ROR1 Small Molecule Inhibitor (KAN0441571C) Induced Significant Apoptosis of Mantle Cell Lymphoma (MCL) Cells

C-Myc-Driven and PRMT5-Dependent Regulation of Multiple Myeloma Cell Proliferation through TNRC6B Gene

Identification of Deubiquitinase OTUD1 As a Novel Player in Resistance of Multiple Myeloma to Bortezomib

In Systemic Masocytosis, Midostaurin Targets Both Kit and Aurora Kinase a Reverting H3K36Me3 Deficiency and Synergizes with Second-Generation Tyrosine Kinase Inhibitors

S100A9 Contributes to T Cell Dysfunction through Its Interaction with RAGE in MDS

Dose-Dependent Iron Chelating Effects of Eltrombopag on in Vitro Human Megakaryopoiesis

DNA Cytosine-Demethylating Agent 5-Aza-2'-Deoxycytidine Targets Leukemia Cells through Reducing DNA N 6 -Methyladenine

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