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Journal Articles

The Anti-Factor XII Antibody AB052 Is Antithrombotic without Hemostatic Impairment in a Primate Model of Extracorporeal Membrane Oxygenation

Michael Wallisch, PhD, Erik I Tucker, PhD, Christina U Lorentz, PhD, Jennifer Johnson, RLATG, Marschelle R Carris, BA, Owen JT McCarty, PhD, Monica T Hinds, PhD, András Gruber, MD

Blood (2017) 130 (Supplement 1): 236.

https://doi.org/10.1182/blood.V130.Suppl_1.236.236

Published: 2017

Journal Articles

Novel Class of Direct Thrombin Inhibitors Prevent Thrombosis By Inhibiting Fibrinogen Cleavage While Preserving Platelet Function

Mohan Sivaraja, PhD, Sivan Sizikov, PhD, Nichole Sandoval, Kenneth Lin, PhD, Lev Igoudin, Subhadra Dash, MSc, Chengpei Xu, MD PhD, Daniel Clemens, PhD, Angels Estiarte, PhD, Timothy Shiau, PhD, Kevin Short, PhD, David Williams, PhD, Anirban Datta, PhD, David Kita, PhD

Blood (2016) 128 (22): 3834.

https://doi.org/10.1182/blood.V128.22.3834.3834

Published: 2016

Journal Articles

Case Series of Pediatric Sickle Retinopathy By Sensitive Clinical Imaging Technologies Suggests Frequent Early Pathology

Pahl A. Daniel, BS, Nancy S. Green, MD, Monica Bhatia, MD, Maureen Licursi, Courtney Briamonte, NP, Elana Smilow, NP, Jonathan S. Chang, MD, Margaret T. Lee, MD MS, Royce W.S. Chen, MD

Blood (2016) 128 (22): 3672.

https://doi.org/10.1182/blood.V128.22.3672.3672

Published: 2016

Journal Articles

Antisense Oligonucleotide Mediated Depletion of Factor XI Prevents Vascular Occlusion in An Experimental Thrombosis Model in Primates

Jeff R. Crosby, PhD, Ulla M Marzec, MS, Chenguang Zhao, Dacao Gao, Alexey S Revenko, PhD, Anton Matafonov, MD, David Gailani, MD, Robert MacLeod, Ph.D., Andras Gruber, MD, Stephen Hanson, PhD, Brett P. Monia, PhD

Blood (2011) 118 (21): 2250.

https://doi.org/10.1182/blood.V118.21.2250.2250

Published: 2011

Journal Articles

Apple Domain-Specific Anti-Factor XI Antibodies Inhibit Venous-Type Thrombosis with Improved Hemostatic Safety Profiles Compared to Enoxaparin in Primates

Erik I. Tucker, PhD, Ulla M Marzec, MS, Philberta Y Leung, PhD, Stephen R Hanson, PhD, Prof., Norah G Verbout, PhD, Sawan Hurst, MS, Owen J.T. McCarty, PhD, David Gailani, MD, Andras Gruber, MD

Blood (2011) 118 (21): 1173.

https://doi.org/10.1182/blood.V118.21.1173.1173

Published: 2011

Journal Articles

YM150, An Oral Direct Factor Xa Inhibitor: Combination with Aspirin or Clopidogrel In Arteriovenous Shunt Thrombosis In Rats

Yoshiyuki Iwatsuki, PhD, Chinatsu Sakata, Yumiko Moritani

Blood (2010) 116 (21): 3318.

https://doi.org/10.1182/blood.V116.21.3318.3318

Published: 2010

Journal Articles

Study on Physician Ordering Behavior on Hypercoaguable Screening Tests

Lucas Wong, MD, Kristen Wortman, MD, Lisa J Go, MD, Paul TIpton, H(ASCP), Juhee Song, PhD, Takeshi Wajima, MD, PhD

Blood (2010) 116 (21): 4745.

https://doi.org/10.1182/blood.V116.21.4745.4745

Published: 2010

Journal Articles

A role for factor XIIa–mediated factor XI activation in thrombus formation in vivo

Qiufang Cheng, Erik I. Tucker, Meghann S. Pine, India Sisler, Anton Matafonov, Mao-fu Sun, Tara C. White-Adams, Stephanie A. Smith, Stephen R. Hanson, Owen J. T. McCarty, Thomas Renné, András Gruber, David Gailani

Blood (2010) 116 (19): 3981–3989.

https://doi.org/10.1182/blood-2010-02-270918

Published: 2010

Includes: Supplemental data

Journal Articles

β 2 -Glycoprotein I Is a Cofactor for t-PA-Mediated Plasminogen Activation.

Chunya Bu, PhD, Lei Gao, PhD, Weidong Xie, Jianwei Zhang, MD, PhD, Yuhong He, Guoping Cai, PhD, Keith McCrae, MD

Blood (2007) 110 (11): 404.

https://doi.org/10.1182/blood.V110.11.404.404

Published: 2007

Journal Articles

Dose-Dependent Antithrombotic Effects of Apixaban, an Oral Direct Factor Xa Inhibitor, in Prevention and Treatment of Thrombosis in Rabbit Models of Arteriovenous-Shunt and Venous Thrombosis at Doses That Preserve Hemostasis.

Pancras C. Wong, Earl J. Crain, Donald J. Pinto, Carol A. Watson

Blood (2007) 110 (11): 933.

https://doi.org/10.1182/blood.V110.11.933.933

Published: 2007

Journal Articles

Inhibition of Factor XI Decreases Thrombin Production and Prevents Vascular Occlusion in Experimental Thrombosis in Primates.

Erik I. Tucker, BS, Ulla M. Marzec, MS, Andras Gruber, MD, Stephen R. Hanson, PhD

Blood (2007) 110 (11): 763.

https://doi.org/10.1182/blood.V110.11.763.763

Published: 2007

Journal Articles

Animal Models of Thrombosis Help Predict the Human Therapeutic Concentration of PRT54021, a Potent Oral Factor Xa Inhibitor.

Keith Abe, Gail Siu, Susan Edwards, Pei Hua Lin, Bing Yan Zhu, Ulla Marzec, Stephen Hanson, Yvonne Pak, Stanley Hollenbach, Uma Sinha

Blood (2006) 108 (11): 901.

https://doi.org/10.1182/blood.V108.11.901.901

Published: 2006

Journal Articles

Antithrombotic Activity of PRT54021, a Potent Oral Direct Factor Xa Inhibitor, Can Be Monitored Using a Novel Prothrombinase Inhibition Bioassay.

Uma Sinha, PhD, Susan T. Edwards, MS, Paul W. Wong, BS, Suzanne M. Delaney, PhD, Nisha Nanda, PhD, Ulla M. Marzec, MS, Yvonne Pak, PhD, Stanley J. Hollenbach, JD, Stephen R. Hanson, PhD

Blood (2006) 108 (11): 907.

https://doi.org/10.1182/blood.V108.11.907.907

Published: 2006

Journal Articles

Dual Inhibition of Blood Coagulation Factors Xa and Iia Synergize To Reduce Thrombus Weight and Thrombin Generation in a Rabbit Arteriovenous Shunt Model of Thrombosis.

Thomas B. McClanahan, MA, Sangita M. Baxi, BS, Liguo Chi, PhD, Tawny Dahring, BS, Weston R. Gould, PhD, Ted Johnson, PhD, Gary Hicks, Kathy Welch, BS, Robert J. Leadley, PhD

Blood (2005) 106 (11): 1866.

https://doi.org/10.1182/blood.V106.11.1866.1866

Published: 2005

Journal Articles

Comparison of Enoxaparin to the Thrombin Variant Protein C Activator, W215A/E217A, in a Primate Model of Thrombosis.

Ulla M. Marzec, Leslie Bush, MA, Andras Gruber, MD, Stephen R. Hanson, PhD, Enrico Di Cera, MD

Blood (2005) 106 (11): 1868.

https://doi.org/10.1182/blood.V106.11.1868.1868

Published: 2005

Journal Articles

Factor XI–dependence of surface- and tissue factor–initiated thrombus propagation in primates

András Gruber, Stephen R. Hanson

Blood (2003) 102 (3): 953–955.

https://doi.org/10.1182/blood-2003-01-0324

Published: 2003

NARROW

The Anti-Factor XII Antibody AB052 Is Antithrombotic without Hemostatic Impairment in a Primate Model of Extracorporeal Membrane Oxygenation

Novel Class of Direct Thrombin Inhibitors Prevent Thrombosis By Inhibiting Fibrinogen Cleavage While Preserving Platelet Function

Case Series of Pediatric Sickle Retinopathy By Sensitive Clinical Imaging Technologies Suggests Frequent Early Pathology

Antisense Oligonucleotide Mediated Depletion of Factor XI Prevents Vascular Occlusion in An Experimental Thrombosis Model in Primates

Apple Domain-Specific Anti-Factor XI Antibodies Inhibit Venous-Type Thrombosis with Improved Hemostatic Safety Profiles Compared to Enoxaparin in Primates

YM150, An Oral Direct Factor Xa Inhibitor: Combination with Aspirin or Clopidogrel In Arteriovenous Shunt Thrombosis In Rats

Study on Physician Ordering Behavior on Hypercoaguable Screening Tests

A role for factor XIIa–mediated factor XI activation in thrombus formation in vivo

β 2 -Glycoprotein I Is a Cofactor for t-PA-Mediated Plasminogen Activation.

Dose-Dependent Antithrombotic Effects of Apixaban, an Oral Direct Factor Xa Inhibitor, in Prevention and Treatment of Thrombosis in Rabbit Models of Arteriovenous-Shunt and Venous Thrombosis at Doses That Preserve Hemostasis.

Inhibition of Factor XI Decreases Thrombin Production and Prevents Vascular Occlusion in Experimental Thrombosis in Primates.

Animal Models of Thrombosis Help Predict the Human Therapeutic Concentration of PRT54021, a Potent Oral Factor Xa Inhibitor.

Antithrombotic Activity of PRT54021, a Potent Oral Direct Factor Xa Inhibitor, Can Be Monitored Using a Novel Prothrombinase Inhibition Bioassay.

Dual Inhibition of Blood Coagulation Factors Xa and Iia Synergize To Reduce Thrombus Weight and Thrombin Generation in a Rabbit Arteriovenous Shunt Model of Thrombosis.

Comparison of Enoxaparin to the Thrombin Variant Protein C Activator, W215A/E217A, in a Primate Model of Thrombosis.

Factor XI–dependence of surface- and tissue factor–initiated thrombus propagation in primates

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American Society of Hematology

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American Society of Hematology

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