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Journal Articles

Targeting the Cyclin D - CDK4/6 - Rb Axis in Mantle Cell Lymphoma with the Novel Translation Inhibitor Silvestrol,

Lapo Alinari, MD., Ph.D., Ryan B. Edwards, Courtney J. Prince, William H. Towns, Rajeswaran Mani, DVM, Amy Lehman, Xiaoli Zhang, PhD, MS, David Jarjoura, PhD, Li Pan, PhD, A. Douglas Kinghorn, PhD, DSc, Michael R. Grever, M.D., Robert A. Baiocchi, M.D., Ph.D., David M. Lucas, PhD
Journal: Blood
Blood (2011) 118 (21): 3498.
https://doi.org/10.1182/blood.V118.21.3498.3498
Published: 2011
Journal Articles

Silvestrol Modulates Direct Anti-Tumor Activity Against Epstein-Barr Virus (EBV)-Associated Lymphomas While Sparing Innate and Antigen Specific Adaptive Immunity

John T. Patton, Mark E Lustberg, MD, PhD, Sabrina L Garman, A Douglas Kinghorn, Ph.D., D.Sc, Li Pan, PhD, David M. Lucas, PhD, Michael R. Grever, M.D., Robert A. Baiocchi, M.D., Ph.D.
Journal: Blood
Blood (2011) 118 (21): 104.
https://doi.org/10.1182/blood.V118.21.104.104
Published: 2011
Journal Articles

Translational Research From the Tropical Forest: Silvestrol, a Natural Product From the Plant Aglaia Foveolata inhibits the Expression of Tyrosine Kinases and Shows a Significant In Vivo Activity in Acute Myeloid Leukemia (AML)

Houda Alachkar, PharmD, M.S, Ramasamy Santhanam, PhD, David M. Lucas, PhD, Sebastian Schwind, MD, Christopher Hickey, M.S, Jiuxia Pang, Danilo Perrotti, MD, PhD, Li Pan, PhD, A Douglas Kinghorn, Ph.D., D.Sc, Guido Marcucci, MD, Michael R Grever, MD
Journal: Blood
Blood (2011) 118 (21): 2616.
https://doi.org/10.1182/blood.V118.21.2616.2616
Published: 2011
Journal Articles

Methylprednisolone-Treatment Induces Dephosphorylation of Syk in B-CLL Cells In Vitro .

Jerina Boelens, MD, Sofie Lust, Mireille Van Gele, PhD, Lara Derycke, PhD, Ann Janssens, MD, Barbara Van Hoecke, PhD, Jan Philippé, MD PhD, Marc Bracke, MD PhD, Martine Poelman, MD, Fritz Offner, MD PhD
Journal: Blood
Blood (2007) 110 (11): 4693.
https://doi.org/10.1182/blood.V110.11.4693.4693
Published: 2007