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Journal Articles

Dynamic CTCF binding directly mediates interactions among cis -regulatory elements essential for hematopoiesis

Qian Qi, Li Cheng, Xing Tang, Yanghua He, Yichao Li, Tiffany Yee, Dewan Shrestha, Ruopeng Feng, Peng Xu, Xin Zhou, Shondra Pruett-Miller, Ross C. Hardison, Mitchell J. Weiss, Yong Cheng

Blood (2021) 137 (10): 1327–1339.

https://doi.org/10.1182/blood.2020005780

Published: 2021

Includes: Supplemental data

Journal Articles

B Cell Restricted Expression of Mutated IKZF3 modulates BCR Signaling and Homing Pathways in a Mouse Model of CLL

Gregory Lazarian, PharmD, Shanye Yin, PhD, Elisa Ten Hacken, PhD, Tomasz Sewastianik, MSc,PhD, Alba Font-tello, PhD, Heather Joyal, Elizabeth Witten, Mei Zheng, Christopher J. Ott, PhD, Donna S Neuberg, ScD, Lili Wang, MD PhD, Ruben D. Carrasco, MD PhD, Catherine J. Wu, MD

Blood (2019) 134 (Supplement_1): 848.

https://doi.org/10.1182/blood-2019-123963

Published: 2019

Journal Articles

Tropomyosin 1 Genetically Constrains in Vitro Megakaryopoiesis

Christopher Thom, MD PhD, Chintan Jobaliya, Kimberly Lorenz, PhD, Jean Ann Maguire, PhD, Alyssa Gagne, Paul Gadue, PhD, Deborah L French, PhD, Benjamin F Voight, PhD

Blood (2019) 134 (Supplement_1): 3612.

https://doi.org/10.1182/blood-2019-121538

Published: 2019

Journal Articles

Editing a γ-Globin Repressor Binding Site Restores Fetal Hemoglobin Synthesis and Corrects the Phenotype of Sickle Cell Disease Erythrocytes

Leslie Weber, Giacomo Frati, Tristan Felix, Clara Wollenschlaeger, Antonio Casini, Vasco Meneghini, Cecile Masson, Anne De Cian, Anne Chalumeau, Fulvio Mavilio, PhD, Mario Amendola, Isabelle André, PhD, Anna Cereseto, Wassim El Nemer, PhD, Jean-Paul Concordet, Carine Giovannangeli, Marina Cavazzana, Annarita Miccio, PhD

Blood (2019) 134 (Supplement_1): 4635.

https://doi.org/10.1182/blood-2019-123192

Published: 2019

Journal Articles

Nascent Transcript and Single Cell Rnaseq Analysis Defines the Mechanism of Action of the LSD1 Inhibitor INCB059872 in Myeloid Leukemia

Gretchen Johnston, Haley E. Ramsey, PhDMSc, Kristy Stengel, PhD, Shilpa Sampathi, PhD, Pankaj Acharya, PhD, Maria Arrate, MSc, Matthew C. Stubbs, PhD, Timothy Burn, PhD, Scott Hiebert, PhD, Michael R. Savona, MD

Blood (2019) 134 (Supplement_1): 2509.

https://doi.org/10.1182/blood-2019-130458

Published: 2019

Journal Articles

The Pathogenesis of Multiple Myeloma (MM) Is Preceded By Mutated Lymphopoiesis and B Cell Oligoclonality That Persist in Patients with Negative Minimal Residual Disease (MRD)

Blood (2019) 134 (Supplement_1): 509.

https://doi.org/10.1182/blood-2019-128049

Published: 2019

Journal Articles

Mechanistic Basis and Efficacy of Targeting β-Catenin-TCF7L2-JMJD6-MYC Axis to Overcome Resistance to BET Inhibitors

Christopher Peter Mill, PhD BA, Warren Fiskus, BSc,PhD, Dyana T. Saenz, PhD, Bernardo H Lara, Vrajesh Karkhanis, PhD, Taghi Manshouri, PhD, Isean Bhalla, Nancy Shao, James V Maher, Srdan Verstovsek, MD PhD, Kapil N. Bhalla, MD

Blood (2019) 134 (Supplement_1): 538.

https://doi.org/10.1182/blood-2019-125142

Published: 2019

Journal Articles

Stag2 Regulates Hematopoietic Differentiation and Self-Renewal through Alterations in Gene Expression and Topological Control

Blood (2019) 134 (Supplement_1): 279.

https://doi.org/10.1182/blood-2019-123464

Published: 2019

Journal Articles

Core Transcriptional Regulatory Circuitries in AML

Maxim Pimkin, MD PhD, Juliana Xavier Ferrucio, PhD, Neekesh Vijay Dharia, MD PhD, Taku Harada, Andrew Kossenkov, Selma Elsarrag, Jazmin Ewers, Charles Y Lin, PhD, Kimberly Stegmaier, MD, Stuart H. Orkin, MD

Blood (2019) 134 (Supplement_1): 280.

https://doi.org/10.1182/blood-2019-129297

Published: 2019

Journal Articles

A Gain of Function Mutation in the NSD2 Histone Methyltransferase Drives Glucocorticoid Resistance Via Blocking Receptor Auto-Induction and BIM/Bmf Expression in ALL

Blood (2019) 134 (Supplement_1): 3758.

https://doi.org/10.1182/blood-2019-126910

Published: 2019

Journal Articles

Flowct: A Semi-Automated Workflow for Deconvolution of Immunophenotypic Data and Objective Reporting on Large Datasets

Blood (2019) 134 (Supplement_1): 4355.

https://doi.org/10.1182/blood-2019-122088

Published: 2019

Journal Articles

Myc and Bet Proteins Orchestrate the Early Regulatory Genome Changes Required for Osteoclast Lineage Commitment

Valentina S Caputo, Nikolaos Trasanidis, Xiaolin Xiao, Mark E Robinson, Alexia Katsarou, Kanagaraju Ponnusamy, Aristeidis Chaidos, Holger W Auner, MD PhD, Irene Roberts, Anastasios Karadimitris

Blood (2019) 134 (Supplement_1): 4329.

https://doi.org/10.1182/blood-2019-125047

Published: 2019

Journal Articles

Cofactor and Cofactor Mimetics

Peter J. Lenting, PhD

Blood (2019) 134 (Supplement_1): SCI-17.

https://doi.org/10.1182/blood-2019-121059

Published: 2019

Journal Articles

Autism-Associated Chromatin Remodeler CHD8 Governs the Survival and Differentiation of Hematopoietic Stem/Progenitor Cells

Zhaowei Tu, PhD, Chen Wang, MSc, Chuntao Zhao, PhD, Lei Huang, PhD, Nathan Salomonis, PhD, Richard Q Lu, PhD, Yi Zheng, PhD

Blood (2019) 134 (Supplement_1): 1191.

https://doi.org/10.1182/blood-2019-127313

Published: 2019

Journal Articles

PRDM1 Binds an Extensive Network of Genes to Regulate Human Natural Killer Cell Homeostasis

Xuxiang Liu, PhD, Yunfei Shi, MD PhD, Yuping Li, PhD, Ru Chen, PhD, Sheng Pan, PhD, Gehong Dong, MD PhD, Qiang Gong, PhD, Javeed Iqbal, PhD, Haiqing Li, PhD, Jinhui Wang, PhD, Shuhua Yi, MD, Timothy McKeithan, MD PhD, Wing C. Chan, MD

Blood (2019) 134 (Supplement_1): 2536.

https://doi.org/10.1182/blood-2019-129270

Published: 2019

Journal Articles

Selective Pressure from Chemotherapy Drives Convergent Evolution in Relapsing and Refractory AML across Age Groups

Timothy Junius Triche, Jr., PhD, Benjamin K. Johnson, PhD, Lyong Heo, MS, Yizhou Peter Huang, BS, Rhonda E. Ries, MA, Hamid Bolouri, PhD, Jason E. Farrar, MD, Soheil Meshinchi, MD PhD

Blood (2018) 132 (Supplement 1): 2609.

https://doi.org/10.1182/blood-2018-99-119323

Published: 2018

Journal Articles

Homozygous Loss of a Critical CTCF Recognition Sequence in the HOXA gene Cluster Eliminates CTCF Binding but Does Not Appreciably Reduce HOXA9 expression in NPM1 Mutated AML Cells

Reza Ghasemi, PhD, Struthers B Heidi, David H Spencer, MD PhD

Blood (2018) 132 (Supplement 1): 2613.

https://doi.org/10.1182/blood-2018-99-119000

Published: 2018

Journal Articles

A Prognostic Human Splicing Signature That Precurses Leukemia

Meenakshi Venkatasubramanian, BS, Xiaoting Chen, PhD, Kashish Chetal, MS, Aishwarya Kulkarni, MS, Kasiani C. Myers, MD, Matthew T. Weirauch, PhD, H. Leighton Grimes, PhD, Nathan Salomonis, PhD

Blood (2018) 132 (Supplement 1): 877.

https://doi.org/10.1182/blood-2018-99-115000

Published: 2018

Journal Articles

KZF-L162R Mutation Affects Splenic Mature B Cell Development and Alters Expression of Aiolos Target Genes

Gregory Lazarian, Shanye Yin, PhD, Alba Font-tello, PhD, Elisa Ten Hacken, PhD, Tomasz Sevastianik, PhD, Daniel Tom, Fara Faye Regis, BS, Amy Gill, Mei Zheng, Katia Georgopoulos, PhD, Donna S Neuberg, ScD, Lili Wang, MDPhD, Ruben D. Carrasco, MD PhD, Catherine J. Wu, MD

Blood (2018) 132 (Supplement 1): 668.

https://doi.org/10.1182/blood-2018-99-115483

Published: 2018

Journal Articles

An Allosteric Mechanism for Epigenetic Activation of the V(D)J Recombinase

Meiling May, BA, Stephen Desiderio, MD PhD, John Thomas Bettridge, BA

Blood (2018) 132 (Supplement 1): 512.

https://doi.org/10.1182/blood-2018-99-116675

Published: 2018

NARROW

Dynamic CTCF binding directly mediates interactions among cis -regulatory elements essential for hematopoiesis

B Cell Restricted Expression of Mutated IKZF3 modulates BCR Signaling and Homing Pathways in a Mouse Model of CLL

Tropomyosin 1 Genetically Constrains in Vitro Megakaryopoiesis

Editing a γ-Globin Repressor Binding Site Restores Fetal Hemoglobin Synthesis and Corrects the Phenotype of Sickle Cell Disease Erythrocytes

Nascent Transcript and Single Cell Rnaseq Analysis Defines the Mechanism of Action of the LSD1 Inhibitor INCB059872 in Myeloid Leukemia

The Pathogenesis of Multiple Myeloma (MM) Is Preceded By Mutated Lymphopoiesis and B Cell Oligoclonality That Persist in Patients with Negative Minimal Residual Disease (MRD)

Mechanistic Basis and Efficacy of Targeting β-Catenin-TCF7L2-JMJD6-MYC Axis to Overcome Resistance to BET Inhibitors

Stag2 Regulates Hematopoietic Differentiation and Self-Renewal through Alterations in Gene Expression and Topological Control

Core Transcriptional Regulatory Circuitries in AML

A Gain of Function Mutation in the NSD2 Histone Methyltransferase Drives Glucocorticoid Resistance Via Blocking Receptor Auto-Induction and BIM/Bmf Expression in ALL

Flowct: A Semi-Automated Workflow for Deconvolution of Immunophenotypic Data and Objective Reporting on Large Datasets

Myc and Bet Proteins Orchestrate the Early Regulatory Genome Changes Required for Osteoclast Lineage Commitment

Cofactor and Cofactor Mimetics

Autism-Associated Chromatin Remodeler CHD8 Governs the Survival and Differentiation of Hematopoietic Stem/Progenitor Cells

PRDM1 Binds an Extensive Network of Genes to Regulate Human Natural Killer Cell Homeostasis

Selective Pressure from Chemotherapy Drives Convergent Evolution in Relapsing and Refractory AML across Age Groups

Homozygous Loss of a Critical CTCF Recognition Sequence in the HOXA gene Cluster Eliminates CTCF Binding but Does Not Appreciably Reduce HOXA9 expression in NPM1 Mutated AML Cells

A Prognostic Human Splicing Signature That Precurses Leukemia

KZF-L162R Mutation Affects Splenic Mature B Cell Development and Alters Expression of Aiolos Target Genes

An Allosteric Mechanism for Epigenetic Activation of the V(D)J Recombinase

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American Society of Hematology

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American Society of Hematology

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