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Journal Articles

Cereblon harnesses Myc-dependent bioenergetics and activity of CD8 + T lymphocytes

Free
Rebecca S. Hesterberg, Matthew S. Beatty, Ying Han, Mario R. Fernandez, Afua A. Akuffo, William E. Goodheart, Chunying Yang, Shiun Chang, Christelle M. Colin, Aileen Y. Alontaga, Jessica M. McDaniel, Adam W. Mailloux, Julia M. R. Billington, Lanzhu Yue, Shonagh Russell, Robert J. Gillies, Sang Y. Yun, Muhammad Ayaz, Nicholas J. Lawrence, Harshani R. Lawrence, Xue-Zhong Yu, Jianing Fu, Lancia N. Darville, John M. Koomen, Xiubao Ren, Jane Messina, Kun Jiang, Timothy J. Garrett, Anjali M. Rajadhyaksha, John L. Cleveland, Pearlie K. Epling-Burnette
Journal: Blood
Blood (2020) 136 (7): 857–870.
https://doi.org/10.1182/blood.2019003257
Published: 2020
Includes: Supplemental data
Journal Articles

Ibrutinib in Combination with Venetoclax Decreases Mitochondrial Bioenergetics through the Impaired BTK, AKT and AMPK/SIRT/PGC-1α Signaling Pathway in CLL

Free
Subir Roy Chowdhury, MD PhD, Amandeep Singh, MSc, Edwin Nguyen, Aaron Marshall, PhD, James B. Johnston, MD, Spencer Bruce Gibson, PhD, Versha Banerji, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1282.
https://doi.org/10.1182/blood-2019-127562
Published: 2019
Journal Articles

Effect of Extended Platelet Storage on Platelet Metabolism and Clot Retraction

Free
Prajeeda M Nair, PhD, Michael Adam Meledeo, PhD, Xiaowu Wu, MD MSc, Grantham Peltier, MS, Bin Liu, BS, Kristin M Reddoch-Cardenas, PhD, James Bynum, PhD, Andrew P. Cap, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2450.
https://doi.org/10.1182/blood-2019-131116
Published: 2019
Journal Articles

Tryptophan Deprivation Promotes an Adaptive Response and Contributes to Bioenergetics in Multiple Myeloma

Free
Alessandra Romano, MDPhD, Nunziatina Laura Parrinello, Katia Todoerti, PhD, Piera La Cava, Fabrizio Puglisi, Cesarina Giallongo, PhD, Daniele Tibullo, Giuseppina Camiolo, Giuseppe Sapienza, MD, Vittorio Del Fabro, MD, Concetta Conticello, Francesco Piazza, Marilena Carrino, PhD, Giuseppe A. Palumbo, MD, Simone Cenci, MD, Antonino Neri, MD, Francesco Di Raimondo, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 4511.
https://doi.org/10.1182/blood-2018-99-116447
Published: 2018
Journal Articles

Metabolic Reprogramming Overcomes T Cell Inhibition By AML Cells

Free
Franziska Maria Uhl, MSc, Sophia Chen, MD, David O'Sullivan, PhD, Michael Buck, PhD, Jörg Büscher, PhD, Dietmar Pfeifer, Jürgen Finke, MD, Justus Duyster, Prof., Hartmut Bertz, MD, Khalid Shoumariyeh, MD, Melanie Börries, PhD, Gesa Richter, MSc, Tobias Madl, PhD, Erika L. Pearce, PhD, Robert Zeiser, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 3328.
https://doi.org/10.1182/blood-2018-99-112897
Published: 2018
Journal Articles

Venetoclax in Combination with NAMPT Inhibitors Decreases Mitochondrial Bioenergetics through the Impaired AMPK/SIRT/PGC1α Signaling Pathway in CLL

Free
Subir Roy Chowdhury, MD PhD, Saleh Ryan, BSc, Cheryl Peltier, BSc, Mandy Squires, CCRP, HIT, Donna Hewitt, R.N., Paul Fernyhough, PhD, Spencer Bruce Gibson, PhD, Versha Banerji, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 1368.
https://doi.org/10.1182/blood-2018-99-112210
Published: 2018
Journal Articles

Hematopoietic-Specific CSNK2B Loss in Mice Causes Impaired Erythropoiesis

Free
Laura Quotti Tubi, PhD, Sara Canovas Nunes, PhD, Marilena Carrino, PhD, Ketty Gianesin, PhD, Sabrina Manni, PhD, Odile Filhol-Cochet, PhD, Brigitte Boldyreff, PhD, Livio Trentin, MD, Gianpietro Semenzato, MD, Francesco Piazza, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 82.
https://doi.org/10.1182/blood.V130.Suppl_1.82.82
Published: 2017
Journal Articles

Arginine Deprivation and Autophagy Sustain Bioenergetics in Multiple Myeloma

Free
Alessandra Romano, MDPhD, Laura Oliva, PhD, Jose Manuel Manteiga, Todoerti Katia, Lorenzo Canziani, Matteo Trudu, Francesca Fontana, Michela Ghizzinardi, Ugo Orfanelli, Magda Marcatti, MD, Fabio Ciceri, MD, Giovanni Tonon, MD PhD, Antonino Neri, MD, Claudio Cerichione, MD PhD, Francesco Di Raimondo, MD, Simone Cenci, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 3051.
https://doi.org/10.1182/blood.V130.Suppl_1.3051.3051
Published: 2017
Journal Articles

Targeting T Cell Bioenergetics By Modulating P-Glycoprotein Selectively Depletes Alloreactive T Cells to Prevent Graft-Versus-Host Disease While Maintaining Antitumor Immunity

Free
Zachariah McIver, DO, PhD, Rebecca Blevins, BS, Benjamin Coe, BS, Jason Grayson, PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 4456.
https://doi.org/10.1182/blood.V130.Suppl_1.4456.4456
Published: 2017
Journal Articles

Waldenstrom Macroglobulinemia Cells Modulate Mitochondrial Bioenergetics and Induce a Respiratory Hyper-Drive State upon Acquisition of Ibrutinib-Resistance

Free
Aneel Paulus, MD, Sharoon Akhtar, MPhil, Roman Hudec, Shumail M. Paulus, MBBS, Yamima Bashir, MBBS, Thomas E. Witzig, MD, Stephen Ansell, MD PhD, Stig Linder, PhD, Sikander Ailawadhi, MD, Asher A. Chanan-Khan, MD
Journal: Blood
Blood (2016) 128 (22): 2761.
https://doi.org/10.1182/blood.V128.22.2761.2761
Published: 2016
Journal Articles

Stromal cell–mediated glycolytic switch in CLL cells involves Notch-c-Myc signaling

Free
Brief Report
Regina Jitschin, Martina Braun, Mirjeta Qorraj, Domenica Saul, Katarina Le Blanc, Thorsten Zenz, Dimitrios Mougiakakos
Journal: Blood
Blood (2015) 125 (22): 3432–3436.
https://doi.org/10.1182/blood-2014-10-607036
Published: 2015
Includes: Supplemental data
Journal Articles

Lineage-Specific Metabolic Reprogramming Reveals LKB1 as Therapeutic Target in Acute Lymphoblastic Leukemia

Free
Lai N Chan, PhD, Daniel Braas, Christian Hurtz, PhD, Seyedmehdi Shojaee, PhD, Behzad Kharabi Masouleh, MD, Huimin Geng, PhD, Thomas Ernst, MD, Andreas Hochhaus, MD, Thomas Graeber, PhD, Markus Muschen, MDPhD
Journal: Blood
Blood (2014) 124 (21): 783.
https://doi.org/10.1182/blood.V124.21.783.783
Published: 2014
Journal Articles

L-Asparaginase Strongly Affects Bioenergetics in Leukemic Cells

Free
Ivana Hermanova, Karel Valis, PhD, Karel Fiser, PhD, Hana Nuskova, Jan Trka, MD, PhD, Julia Starkova, PhD
Journal: Blood
Blood (2012) 120 (21): 779.
https://doi.org/10.1182/blood.V120.21.779.779
Published: 2012
Journal Articles

Cellular Bioenergetics in Lymphoid Neoplasia

Free
Matthew Vander Heiden, MD, PhD
Journal: Blood
Blood (2011) 118 (21): SCI-25.
https://doi.org/10.1182/blood.V118.21.SCI-25.SCI-25
Published: 2011
Journal Articles

Mitochondrial Physiology in Health and Disease: Changes with Aging.

Free
Douglas C. Wallace, PHD
Journal: Blood
Blood (2009) 114 (22): SCI-1.
https://doi.org/10.1182/blood.V114.22.SCI-1.SCI-1
Published: 2009
Journal Articles

UCP2 Modulates Cell Proliferation through the MAPK/ERK Pathway during Erythropoiesis and Has No Effect on Heme Biosynthesis

Free
Alvaro A Elorza, PhD, Brigham B Hyde, Hanna Mikkola, MD, PhD, Sheila Collins, PhD, Orian S Shirihai, MD/PhD
Journal: Blood
Blood (2008) 112 (11): 5372.
https://doi.org/10.1182/blood.V112.11.5372.5372
Published: 2008
Journal Articles

Pre-Clincial Evaluation of a Novel Purine Analogue 8-NH 2 -Adenosine in Mantle Cell Lymphoma Indicates Efficacy Via Alterations in RNA/DNA Synthesis and Cellular Bioenergetics

Free
Mala Shanmugam, Ph.D., Jennifer Dennison, Ph.D., Jun Qian, M.D., Varsha Gandhi, PhD, Mary Ayres, Amareshwar Singh, PhD, Samuel McBrayer, Carter Neugarten, Priya Shanmugam, Karthik Singh, Leo I. Gordon, MD, Nancy Krett, PhD, Steven T. Rosen, MD
Journal: Blood
Blood (2008) 112 (11): 4987.
https://doi.org/10.1182/blood.V112.11.4987.4987
Published: 2008
Journal Articles

Overexpression of Apoptosis-Inducing Factor (AIF) and Pro-Survival Function in AML.

Free
Rui-Yu Wang, MD, PhD, Vivian R. Ruvolo, Teresa McQueen, Wendy D. Schober, Steven Kornblau, MD, Marina Konopleva, M.D., Ph.D., Michael Andreeff, M.D., PhD.
Journal: Blood
Blood (2006) 108 (11): 4395.
https://doi.org/10.1182/blood.V108.11.4395.4395
Published: 2006