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Journal Articles

Exploitation of a Newly Characterized Metabolic-Cytoskeletal Axis for Effective Combination Therapy of Iron Restricted Anemia

Adam N Goldfarb, MD, Katie Freeman, BA, Alejandro Ariel Gru, MD, Zollie White, III, MS, Lorrie L Delehanty, BS

Blood (2019) 134 (Supplement_1): 2233.

https://doi.org/10.1182/blood-2019-129172

Published: 2019

Journal Articles

Elucidating the Role of IL6 in Stress Erythropoiesis and in the Development of Anemia Under Inflammatory Conditions

Sayantani Sinha, PhD, Ritama Gupta, PhD, Jianbing Zhang, PhD, Amaliris Guerra, PhD, Ping La, Sara Gardenghi, PhD, Stefano Rivella, PhD

Blood (2019) 134 (Supplement_1): 940.

https://doi.org/10.1182/blood-2019-128826

Published: 2019

Journal Articles

TP-0184 Inhibits ALK2/ACVR1, Decreases Hepcidin Levels, and Demonstrates Activity in Preclinical Mouse Models of Functional Iron Deficiency

Peter Peterson, PhD, W K, Clifford Whatcott, PhD, Adam Siddiqui-Jain, PhD, Steven Weitman, MD PhD, Mark Kieran, MD PhD, David J. Bearss, PhD, Steven L. Warner, PhD

Blood (2017) 130 (Supplement 1): 937.

https://doi.org/10.1182/blood.V130.Suppl_1.937.937

Published: 2017

Journal Articles

Clinical Analysis of Gram-Negative Bacillisepticemia-Associated Hemophagocytic Lymphohistiocytosis

Meng Song, Hongxia Qiu, MD PhD

Blood (2017) 130 (Supplement 1): 2292.

https://doi.org/10.1182/blood.V130.Suppl_1.2292.2292

Published: 2017

Journal Articles

Absence of Interleukin-6 Protects Murine Bone Marrow Erythropoiesis Under Inflammation, in a Process Reversible By Iron Mediated Reactive Oxygen Species Upregulation

Ritama Gupta, PhD, Roberta Chessa, PhD, La Ping, PhD, Vania Lo Presti, Sara Gardenghi, PhD, Stefano Rivella, PhD

Blood (2017) 130 (Supplement 1): 2195.

https://doi.org/10.1182/blood.V130.Suppl_1.2195.2195

Published: 2017

Journal Articles

Absence of TNF-α Promotes Anemia of Inflammation and Inflammatory Bowel Disease

Ritama Gupta, PhD, Lo Presti Vania, Carla Casu, PhD, Rea Oikonomidou, MD, Emir OHara, Stefano Rivella, PhD

Blood (2017) 130 (Supplement 1): 3577.

https://doi.org/10.1182/blood.V130.Suppl_1.3577.3577

Published: 2017

Journal Articles

The ALK-2 Inhibitor, TP-0184, Demonstrates High Distribution to the Liver Contributing to Significant Preclinical Efficacy in Mouse Models of Anemia of Chronic Disease

Peter Peterson, PhD, Wontak Kim, Hillary Haws, Clifford J. Whatcott, PhD, Adam Siddiqui-Jain, PhD, David J. Bearss, PhD, Steven L. Warner, PhD

Blood (2016) 128 (22): 263.

https://doi.org/10.1182/blood.V128.22.263.263

Published: 2016

Journal Articles

ALK2 Inhibition Via TP-0184 Abrogates Inflammation-Induced Hepcidin Expression and Is a Potential Therapeutic for Anemia of Chronic Disease

Peter Peterson, PhD, Katherine K. Soh, Ye Sol Lee, Wontak Kim, Clifford J. Whatcott, PhD, Adam Siddiqui-Jain, PhD, David J. Bearss, PhD, Steven L. Warner, PhD

Blood (2015) 126 (23): 273.

https://doi.org/10.1182/blood.V126.23.273.273

Published: 2015

Journal Articles

A Double Knock out of Hepcidin and IL6 Demonstrates Independent Roles of the Two Genes in Anemia of Inflammation

Ritama Gupta, MSc, Sara Gardenghi, PhD, Lori Bystrom, PhD, Roberta Chessa, PhD, Stefano Rivella, PhD

Blood (2015) 126 (23): 2221.

https://doi.org/10.1182/blood.V126.23.2221.2221

Published: 2015

Journal Articles

Role of Erythroferrone in the Pathophysiology of Common Anemias

Leon Kautz, PhD, Grace Jung, MS, Elizabeta Nemeth, PhD, Tomas Ganz, MD PhD

Blood (2014) 124 (21): 213.

https://doi.org/10.1182/blood.V124.21.213.213

Published: 2014

Journal Articles

Isocitrate Reverses Anemia of Inflammation in a Mouse Model Treated with Heat-Killed Brucella Abortus

Sona Parikh, BS, Eileen Fung, PhD, Elizabeta Nemeth, PhD, Tomas Ganz, MD PhD, Airie Kim, MD

Blood (2014) 124 (21): 1349.

https://doi.org/10.1182/blood.V124.21.1349.1349

Published: 2014

Journal Articles

A mouse model of anemia of inflammation: complex pathogenesis with partial dependence on hepcidin

Airie Kim, Eileen Fung, Sona G. Parikh, Erika V. Valore, Victoria Gabayan, Elizabeta Nemeth, Tomas Ganz

Blood (2014) 123 (8): 1129–1136.

https://doi.org/10.1182/blood-2013-08-521419

Published: 2014

Includes: Supplemental data

Journal Articles

Distinct roles for hepcidin and interleukin-6 in the recovery from anemia in mice injected with heat-killed Brucella abortus

Sara Gardenghi, Tom M. Renaud, Alessandra Meloni, Carla Casu, Bart J. Crielaard, Laura M. Bystrom, Noa Greenberg-Kushnir, Barbra J. Sasu, Keegan S. Cooke, Stefano Rivella

Blood (2014) 123 (8): 1137–1145.

https://doi.org/10.1182/blood-2013-08-521625

Published: 2014

Includes: Supplemental data

Journal Articles

Distinct Roles For Hepcidin and Interleukin 6 In The Recovery From Anemia Following Administration Of Heat-Killed Brucella Abortus

Sara Gardenghi, PhD, Thomas M. Renaud, MD, Alessandra Meloni, PhD, Carla Casu, PhD, Bart J. Crielaard, PhD, Laura M. Bystrom, PhD, Noa Greenberg, MD, Barbra J. Sasu, PhD, Keegan S. Cooke, Stefano Rivella, PhD

Blood (2013) 122 (21): 430.

https://doi.org/10.1182/blood.V122.21.430.430

Published: 2013

Journal Articles

Investigating the Role of Cytokines and Hepcidin in Anemia of Inflammation

Sara Gardenghi, PhD, Thomas M. Renaud, MD, Alessandra Meloni, PhD, Pedro Ramos, PhD, Carla Casu, PhD, Keegan S Cooke, Barbra J Sasu, PhD, Patricia Giardina, MD, Robert W Grady, PhD, Stefano Rivella, PhD

Blood (2011) 118 (21): 1046.

https://doi.org/10.1182/blood.V118.21.1046.1046

Published: 2011

Journal Articles

The Role of Interleukin-6 and Bone-Marrow Derived Cell Production of Hepcidin In Anemia of Inflammation

Thomas M. Renaud, MD, Stefano Rivella, PhD

Blood (2010) 116 (21): 167.

https://doi.org/10.1182/blood.V116.21.167.167

Published: 2010

Journal Articles

Hepcidin Independent Anemia of Inflammation

Seth Rivera, M.D., Ph.D., Sophie Vaulont, Ph.D., Dana Shprung, Donald Limbrick, Tomas Ganz, MD, PhD

Blood (2010) 116 (21): 2050.

https://doi.org/10.1182/blood.V116.21.2050.2050

Published: 2010

Journal Articles

Fully Human Anti-Hepcidin Antibodies Mobilize Iron and Treat Inflammatory Anemia in a Mouse Model.

Keegan S Cooke, Adrienne Augustic, Jeanne Sloan, Linh Tran, Tara L Arvedson, Ph.D., Todd Juan, Barbra J Sasu, PhD

Blood (2009) 114 (22): 626.

https://doi.org/10.1182/blood.V114.22.626.626

Published: 2009

NARROW

Exploitation of a Newly Characterized Metabolic-Cytoskeletal Axis for Effective Combination Therapy of Iron Restricted Anemia

Elucidating the Role of IL6 in Stress Erythropoiesis and in the Development of Anemia Under Inflammatory Conditions

TP-0184 Inhibits ALK2/ACVR1, Decreases Hepcidin Levels, and Demonstrates Activity in Preclinical Mouse Models of Functional Iron Deficiency

Clinical Analysis of Gram-Negative Bacillisepticemia-Associated Hemophagocytic Lymphohistiocytosis

Absence of Interleukin-6 Protects Murine Bone Marrow Erythropoiesis Under Inflammation, in a Process Reversible By Iron Mediated Reactive Oxygen Species Upregulation

Absence of TNF-α Promotes Anemia of Inflammation and Inflammatory Bowel Disease

The ALK-2 Inhibitor, TP-0184, Demonstrates High Distribution to the Liver Contributing to Significant Preclinical Efficacy in Mouse Models of Anemia of Chronic Disease

ALK2 Inhibition Via TP-0184 Abrogates Inflammation-Induced Hepcidin Expression and Is a Potential Therapeutic for Anemia of Chronic Disease

A Double Knock out of Hepcidin and IL6 Demonstrates Independent Roles of the Two Genes in Anemia of Inflammation

Role of Erythroferrone in the Pathophysiology of Common Anemias

Isocitrate Reverses Anemia of Inflammation in a Mouse Model Treated with Heat-Killed Brucella Abortus

A mouse model of anemia of inflammation: complex pathogenesis with partial dependence on hepcidin

Distinct roles for hepcidin and interleukin-6 in the recovery from anemia in mice injected with heat-killed Brucella abortus

Distinct Roles For Hepcidin and Interleukin 6 In The Recovery From Anemia Following Administration Of Heat-Killed Brucella Abortus

Investigating the Role of Cytokines and Hepcidin in Anemia of Inflammation

The Role of Interleukin-6 and Bone-Marrow Derived Cell Production of Hepcidin In Anemia of Inflammation

Hepcidin Independent Anemia of Inflammation

Fully Human Anti-Hepcidin Antibodies Mobilize Iron and Treat Inflammatory Anemia in a Mouse Model.

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American Society of Hematology

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ASH Publications

American Society of Hematology

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